199 research outputs found
L\u27Insitut Jacques Cartier Letter to Armand Dutil
Letter from members of L\u27Institut Jacques Cartier to Armand Dutil, President of Club Raquetteur Jacques Cartier.https://digitalcommons.usm.maine.edu/fac-le-club-jacques-cartier/1018/thumbnail.jp
Design of a 3D printer head for additive manufacturing of sugar glass for tissue engineering applications
Additive manufacturing is now considered as a new paradigm that is foreseen to improve progress in many fields. The field of tissue engineering has been facing the need for tissue vascularization when producing thick tissues. The use of sugar glass as a fugitive ink to produce vascular networks through rapid casting may offer the key to vascularization of thick tissues produced by tissue engineering. Here, a 3D printer head capable of producing complex structures out of sugar glass is presented. This printer head uses a motorized heated syringe fitted with a custom made nozzle. The printer head was adapted to be mounted on a commercially available 3D printer. A mathematical model was derived to predict the diameter of the filaments based on the printer head feed rate and extrusion rate. Using a 1 mm diameter nozzle, the printer accurately produced filaments ranging from 0.3 mm to 3.2 mm in diameter. One of the main advantages of this manufacturing method is the self-supporting behaviour of sugar glass that allows the production of long, horizontal, curved, as well as overhanging filaments needed to produce complex vascular networks. Finally, to establish a proof of concept, polydimethylsiloxane was used as the gel matrix during the rapid casting to produce various “vascularized” constructs that were successfully perfused, which suggests that this new fabrication method can be used in a number of tissue engineering applications, including the vascularization of thick tissues
Gas-Phase Oxygen Gradients in Strongly Interacting Galaxies: I. Early-Stage Interactions
A consensus is emerging that interacting galaxies show depressed nuclear gas
metallicities compared to isolated star-forming galaxies. Simulations suggest
that this nuclear underabundance is caused by interaction-induced inflow of
metal-poor gas, and that this inflow concurrently flattens the radial
metallicity gradients in strongly interacting galaxies. We present
metallicities of over 300 HII regions in a sample of 16 spirals that are
members of strongly interacting galaxy pairs with mass ratio near unity. The
deprojected radial gradients in these galaxies are about half of those in a
control sample of isolated, late-type spirals. Detailed comparison of the
gradients with simulations show remarkable agreement in gradient distributions,
the relationship between gradients and nuclear underabundances, and the shape
of profile deviations from a straight line. Taken together, this evidence
conclusively demonstrates that strongly interacting galaxies at the present day
undergo nuclear metal dilution due to gas inflow, as well as significant
flattening of their gas-phase metallicity gradients, and that current
simulations can robustly reproduce this behavior at a statistical level.Comment: Accepted for publication in Ap
Galactic Evolution along the Hubble Sequence
A generalization of the multiphase chemical evolution model applied to a wide
set of theoretical galaxies is shown. This set of models has been computed by
using the so-called Universal Rotation Curve from Persic, Salucci & Steel to
calculate the radial mass distributions of each theoretical galaxy. By assuming
that the molecular cloud and star formation efficiencies depend on the
morphological type of each galaxy, we construct a bi-parametric grid of models
whose results are valid in principle for any spiral galaxy, of given maximum
rotation velocity or total mass, and morphological type.Comment: Proceedings of the Euroconference "The Evolution of Galaxies. III..."
(Kiel 2002
Oxygen and nitrogen abundances of HII regions in six spiral galaxies
Spectroscopic observations of 63 HII regions in six spiral galaxies (NGC 628,
NGC 783, NGC 2336, NGC 6217, NGC 7331, and NGC 7678) were carried out with the
6-meter telescope (BTA) of Russian Special Astrophysical Observatory with the
Spectral Camera attached to the focal reducer SCORPIO in the multislit mode
with a dispersion of 2.1A/pixel and a spectral resolution of 10A. These
observations were used to estimate the oxygen and nitrogen abundances and the
electron temperatures in HII regions through the recent variant of the strong
line method (NS calibration). The parameters of the radial distribution (the
extrapolated central intercept value and the gradient) of the oxygen and
nitrogen abundances in the disks of spiral galaxies NGC 628, NGC 783, NGC 2336,
NGC 7331, and NGC 7678 have been determined. The abundances in the NGC 783, NGC
2336, NGC 6217, and NGC 7678 are measured for the first time. Galaxies from our
sample follow well the general trend in the luminosity - central metallicity
diagram for spiral and irregular galaxies.Comment: 11 pages, 7 figures, 6 tables. Accepted for publication in MNRA
Evidence for Intrinsic Redshifts in Normal Spiral Galaxies
The Tully-Fisher Relationship (TFR) is utilized to identify anomalous
redshifts in normal spiral galaxies. Three redshift anomalies are identified in
this analysis: (1) Several clusters of galaxies are examined in which late type
spirals have significant excess redshifts relative to early type spirals in the
same clusters, (2) Galaxies of morphology similar to ScI galaxies are found to
have a systematic excess redshift relative to the redshifts expected if the
Hubble Constant is 72 km s-1 Mpc-1, (3) individual galaxies, pairs, and groups
are identified which strongly deviate from the predictions of a smooth Hubble
flow. These redshift deviations are significantly larger than can be explained
by peculiar motions and TFR errors. It is concluded that the redshift anomalies
identified in this analysis are consistent with previous claims for large
non-cosmological (intrinsic) redshifts.Comment: Accepted for publication at Astrophysics&Space Science. 36 pages
including 8 tables and 7 figure
An Aromatic Inventory of the Local Volume
Using infrared photometry from the Spitzer Space Telescope, we perform the
first inventory of aromatic feature emission (AFE, but also commonly referred
to as PAH emission) for a statistically complete sample of star-forming
galaxies in the local volume. The photometric methodology involved is
calibrated and demonstrated to recover the aromatic fraction of the IRAC 8
micron flux with a standard deviation of 6% for a training set of 40 SINGS
galaxies (ranging from stellar to dust dominated) with both suitable
mid-infrared Spitzer IRS spectra and equivalent photometry. A potential factor
of two improvement could be realized with suitable 5.5 and 10 micron
photometry, such as what may be provided in the future by JWST. The resulting
technique is then applied to mid-infrared photometry for the 258 galaxies from
the Local Volume Legacy (LVL) survey, a large sample dominated in number by
low-luminosity dwarf galaxies for which obtaining comparable mid-infrared
spectroscopy is not feasible. We find the total LVL luminosity due to five
strong aromatic features in the 8 micron complex to be 2.47E10 solar
luminosities with a mean volume density of 8.8E6 solar luminosities per cubic
Megaparsec. Twenty-four of the LVL galaxies, corresponding to a luminosity cut
at M = -18.22 in the B band, account for 90% of the aromatic luminosity. Using
oxygen abundances compiled from the literature for 129 of the 258 LVL galaxies,
we find a correlation between metallicity and the aromatic to total infrared
emission ratio but not the aromatic to total 8 micron dust emission ratio. A
possible explanation is that metallicity plays a role in the abundance of
aromatic molecules relative to the total dust content, but other factors such
as star formation and/or the local radiation field affect the excitation of
those molecules.Comment: ApJ in press; 29 pages, 14 figures, 3 tables; emulateapj forma
Reconstructing native American migrations from whole-genome and whole-exome data.
There is great scientific and popular interest in understanding the genetic history of populations in the Americas. We wish to understand when different regions of the continent were inhabited, where settlers came from, and how current inhabitants relate genetically to earlier populations. Recent studies unraveled parts of the genetic history of the continent using genotyping arrays and uniparental markers. The 1000 Genomes Project provides a unique opportunity for improving our understanding of population genetic history by providing over a hundred sequenced low coverage genomes and exomes from Colombian (CLM), Mexican-American (MXL), and Puerto Rican (PUR) populations. Here, we explore the genomic contributions of African, European, and especially Native American ancestry to these populations. Estimated Native American ancestry is 48% in MXL, 25% in CLM, and 13% in PUR. Native American ancestry in PUR is most closely related to populations surrounding the Orinoco River basin, confirming the Southern American ancestry of the Taíno people of the Caribbean. We present new methods to estimate the allele frequencies in the Native American fraction of the populations, and model their distribution using a demographic model for three ancestral Native American populations. These ancestral populations likely split in close succession: the most likely scenario, based on a peopling of the Americas 16 thousand years ago (kya), supports that the MXL Ancestors split 12.2kya, with a subsequent split of the ancestors to CLM and PUR 11.7kya. The model also features effective populations of 62,000 in Mexico, 8,700 in Colombia, and 1,900 in Puerto Rico. Modeling Identity-by-descent (IBD) and ancestry tract length, we show that post-contact populations also differ markedly in their effective sizes and migration patterns, with Puerto Rico showing the smallest effective size and the earlier migration from Europe. Finally, we compare IBD and ancestry assignments to find evidence for relatedness among European founders to the three populations
Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data
There is great scientific and popular interest in understanding the genetic history of populations in the Americas. We wish to understand when different regions of the continent were inhabited, where settlers came from, and how current inhabitants relate genetically to earlier populations. Recent studies unraveled parts of the genetic history of the continent using genotyping arrays and uniparental markers. The 1000 Genomes Project provides a unique opportunity for improving our understanding of population genetic history by providing over a hundred sequenced low coverage genomes and exomes from Colombian (CLM), Mexican-American (MXL), and Puerto Rican (PUR) populations. Here, we explore the genomic contributions of African, European, and especially Native American ancestry to these populations. Estimated Native American ancestry is 48% in MXL, 25% in CLM, and 13% in PUR. Native American ancestry in PUR is most closely related to populations surrounding the Orinoco River basin, confirming the Southern America ancestry of the Taíno people of the Caribbean. We present new methods to estimate the allele frequencies in the Native American fraction of the populations, and model their distribution using a demographic model for three ancestral Native American populations. These ancestral populations likely split in close succession: the most likely scenario, based on a peopling of the Americas 16 thousand years ago (kya), supports that the MXL Ancestors split 12.2kya, with a subsequent split of the ancestors to CLM and PUR 11.7kya. The model also features effective populations of 62,000 in Mexico, 8,700 in Colombia, and 1,900 in Puerto Rico. Modeling Identity-by-descent (IBD) and ancestry tract length, we show that post-contact populations also differ markedly in their effective sizes and migration patterns, with Puerto Rico showing the smallest effective size and the earlier migration from Europe. Finally, we compare IBD and ancestry assignments to find evidence for relatedness among European founders to the three populations.Facultad de Ciencias Naturales y MuseoInstituto Multidisciplinario de Biología Celula
Heterogeneity in Genetic Admixture across Different Regions of Argentina
The population of Argentina is the result of the intermixing between several groups, including Indigenous American, European and African populations. Despite the commonly held idea that the population of Argentina is of mostly European origin, multiple studies have shown that this process of admixture had an impact in the entire Argentine population. In the present study we characterized the distribution of Indigenous American, European and African ancestry among individuals from different regions of Argentina and evaluated the level of discrepancy between self-reported grandparental origin and genetic ancestry estimates. A set of 99 autosomal ancestry informative markers (AIMs) was genotyped in a sample of 441 Argentine individuals to estimate genetic ancestry. We used non-parametric tests to evaluate statistical significance. The average ancestry for the Argentine sample overall was 65% European (95%CI: 63–68%), 31% Indigenous American (28–33%) and 4% African (3–4%). We observed statistically significant differences in European ancestry across Argentine regions [Buenos Aires province (BA) 76%, 95%CI: 73–79%; Northeast (NEA) 54%, 95%CI: 49–58%; Northwest (NWA) 33%, 95%CI: 21–41%; South 54%, 95%CI: 49–59%; p<0.0001] as well as between the capital and immediate suburbs of Buenos Aires city compared to more distant suburbs [80% (95%CI: 75–86%) versus 68% (95%CI: 58–77%), p = 0.01]. European ancestry among individuals that declared all grandparents born in Europe was 91% (95%CI: 88–94%) compared to 54% (95%CI: 51–57%) among those with no European grandparents (p<0.001). Our results demonstrate the range of variation in genetic ancestry among Argentine individuals from different regions in the country, highlighting the importance of taking this variation into account in genetic association and admixture mapping studies in this population
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