50 research outputs found
Estudo do mercado de moda sustentável para a Austrália
Australia como continente insular, con más de 25 millones de habitantes y un PIB per cápita de USD56.420, en comparación con el número brasileño de USD14.140, demuestra un poder adquisitivo relativamente superior al del consumidor brasileño. Australia fue uno de los precursores en el consumo consciente de moda y moda sostenible, centrándose en piezas más duraderas. A pesar de que Australia proyecta una importación textil con un crecimiento del 34% para los próximos años, Brasil prácticamente no ocupa una posición significativa en el ranking de exportadores del producto. El análisis de mercado que se presenta busca en uno de los principales nichos de mercado del sector textil australiano, la ropa de playa, una oportunidad para ganar representación de Brasil en Australia.A Austrália como um continente-ilha, com mais de 25 milhões de habitantes e com um PIB per capita de USD56,420, face ao número brasileiro de USD14,140, demonstra um poder de compra relativamente superior ao do consumidor brasileiro. A Austrália foi uma das precursoras no consumo consciente da moda e também da moda sustentável, prezando por peças mais duráveis. Apesar da Austrália projetar uma importação de têxtil com um crescimento de 34% para os próximos anos, o Brasil praticamente não ocupa nenhuma posição significativa no ranking de exportadores do produto. A análise de mercado que se apresenta, busca em um dos principais nichos de mercado no setor têxtil australiano, a moda praia, uma oportunidade para ganhar representatividade do Brasil junto a Austrália
Estudo do mercado português para o setor de tecnologia
Brasil y Portugal comparten una relación privilegiada, como se evidencia en la cooperación y acciones coordinadas político-diplomáticas, económicas, sociales, culturales, legales, técnicas y científicas. Por tanto, para el mercado en estudio, la tecnología, existen grandes oportunidades no solo por la facilidad, sino también por el lenguaje común. Hay socios dispuestos a ayudar en los proyectos de expansión de empresas tecnológicas de Brasil a otros países, uno de los principales es Portugal. Es necesario tener en cuenta la probable necesidad de cambiar la herramienta para satisfacer el mercado objetivo, pero la proximidad cultural y lingüística hace que esta distancia sea menor. Existen varios mecanismos que fomentan este proceso.Brasil e Portugal compartilham de uma relação privilegiada, como evidenciado em cooperações e ações coordenadas político-diplomáticas, bem como econômicas, sociais, culturais, jurídicas, técnicas e científicas. Logo, para o mercado em estudo, tecnologia, se vê grandes oportunidades não somente pela facilidade, como também pelo idioma em comum. Existem parceiros dispostos a auxiliar os projetos de expansão de empresas de tecnologia do Brasil para outros países, um dos principais é Portugal. Necessário observar a provável necessidade de alteração na ferramenta para atender o mercado alvo, mas a proximidade cultural e de idioma torna esta distância menor. Existem diversos mecanismos incentivadores neste processo
Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and North America during the 1960s. Due to the lack of epidemiological and genomic data, the reasons for this emergence are unknown. Here we show by comparative genome analysis and phylogenetic reconstruction of 229 isolates that the rise of human GBS infections corresponds to the selection and worldwide dissemination of only a few clones. The parallel expansion of the clones is preceded by the insertion of integrative and conjugative elements conferring tetracycline resistance (TcR). Thus, we propose that the use of tetracycline from 1948 onwards led in humans to the complete replacement of a diverse GBS population by only few TcR clones particularly well adapted to their host, causing the observed emergence of GBS diseases in neonates. \ua9 2014 Macmillan Publishers Limited. All rights reserved
Time course of the hemodynamic responses to aortic depressor nerve stimulation in conscious spontaneously hypertensive rats
Using fish models to investigate the links between microbiome and social behaviour: the next step for translational microbiome research?
Recent research has revealed surprisingly important connections between animals’ microbiome and social behaviour. Social interactions can affect the composition and function of the microbiome; conversely, the microbiome affects social communication by influencing the hosts’ central nervous system and peripheral chemical communication. These discoveries set the stage for novel research focusing on the evolution and physiology of animal social behaviour in relation to microbial transmission strategies. Here, we discuss the emerging roles of teleost fish models and their potential for advancing research fields, linked to sociality and microbial regulation. We argue that fish models, such as the zebrafish (Danio rerio, Cyprinidae), sticklebacks (Gasterosteidae), guppies (Poeciliidae) and cleaner–client dyads (e.g., obligate cleaner fish from the Labridae and Gobiidae families and their visiting clientele), will provide valuable insights into the roles of microbiome in shaping social behaviour and vice versa, while also being of direct relevance to the food and ornamental fish trades. The diversity of fish behaviour warrants more interdisciplinary research, including microbiome studies, which should have a strong ecological (field‐derived) approach, together with laboratory‐based cognitive and neurobiological experimentation. The implications of such integrated approaches may be of translational relevance, opening new avenues for future investigation using fish models
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
Meeting abstrac
The role of cinnamon as a modulator of the expression of genes related to antioxidant activity and lipid metabolism of laying quails
Since cinnamon has vitamins and minerals in addition to antioxidants compounds in its chemical composition studies have shown the potential of cinnamon supplementation on some important characteristics in the performance of birds. Thus, this study was conducted under the hypothesis that the inclusion of cinnamon in the laying quail diet could influence the performance of the birds through the expression of genes related to antioxidant activity and lipid metabolism. To test this hypothesis, 144 Japanese quail (Coturnix japonica) with an initial age of 18 weeks and average weight of 133g were distributed in a completely randomized design with two treatments: no cinnamon supplementation (NCS—control group) and with supplementation of 9g/kg of cinnamon powder (CPS). The experiment lasted for 84 days. At the end of the experimental period, six animals from each treatment were euthanized by cervical dislocation, blood was collected and organs weighed. Liver tissue was collected for gene expression and biochemical analyses. We observed a significant effect of cinnamon inclusion on the weight of the pancreas (P = 0.0418), intestine (P = 0.0209) and ovary (P = 0.0389). Lower weights of the pancreas and intestine, and a higher ovary weight was observed in birds receiving the CPS diet. Quails fed with cinnamon supplementation also had better feed conversion per egg mass (2.426 g /g, P = 0.0126), and higher triglyceride (1516.60 mg/dL, P = 0.0207), uric acid (7.40 mg/dL, P = 0.0003) and VLDL (300.40 mg/dL, P = 0.0252) contents. A decreased content of thiobarbituric acid reactive substances (TBARS) and lower catalase activity was observed in the liver of quails from the CPS diet (0.086 nmoles/mg PTN, and 2.304 H2O2/min/mg PTN, respectively). Quails from the CPS group presented significantly greater expression of FAS (fatty acid synthase, 36,03 AU), ACC (Acetyl-CoA Carboxylase, 31.33 AU), APOAI (apolipoprotein A-I, 803,9 AU), ESR2 (estrogen receptor 2, 0.73 AU) SOD (superoxide dismutase, 4,933.9 AU) and GPx7 (glutathione peroxidase 7, 9.756 AU) than quails from the control group. These results allow us to suggest that cinnamon powder supplementation in the diet of laying quails can promote balance in the metabolism and better performance through the modulation of antioxidant activity and the expression of genes related to lipid metabolism
25th annual computational neuroscience meeting: CNS-2016
The same neuron may play different functional roles in the neural circuits to which it belongs. For example, neurons in the Tritonia pedal ganglia may participate in variable phases of the swim motor rhythms [1]. While such neuronal functional variability is likely to play a major role the delivery of the functionality of neural systems, it is difficult to study it in most nervous systems. We work on the pyloric rhythm network of the crustacean stomatogastric ganglion (STG) [2]. Typically network models of the STG treat neurons of the same functional type as a single model neuron (e.g. PD neurons), assuming the same conductance parameters for these neurons and implying their synchronous firing [3, 4]. However, simultaneous recording of PD neurons shows differences between the timings of spikes of these neurons. This may indicate functional variability of these neurons. Here we modelled separately the two PD neurons of the STG in a multi-neuron model of the pyloric network. Our neuron models comply with known correlations between conductance parameters of ionic currents. Our results reproduce the experimental finding of increasing spike time distance between spikes originating from the two model PD neurons during their synchronised burst phase. The PD neuron with the larger calcium conductance generates its spikes before the other PD neuron. Larger potassium conductance values in the follower neuron imply longer delays between spikes, see Fig. 17.Neuromodulators change the conductance parameters of neurons and maintain the ratios of these parameters [5]. Our results show that such changes may shift the individual contribution of two PD neurons to the PD-phase of the pyloric rhythm altering their functionality within this rhythm. Our work paves the way towards an accessible experimental and computational framework for the analysis of the mechanisms and impact of functional variability of neurons within the neural circuits to which they belong