8,774 research outputs found
Junior Recital, Mason Klein, trumpet
Junior RecitalMason Klein, trumpetRussell Wilson, pianoTuesday, December 3, 2019 at 7pmRecital HallJames W. Black Music Center1015 Grove AvenueRichmond, Va.The presentation of this junior recital will fulfill in part the requirements for the Bachelor of Music Degree in Music Education. Mason Klein studies trumpet with Rex Richardso
The influence of a DDGS diet on the development and oviposition rate of Tribolium castaneum (Herbst)
Dried Distillers Grains with Solubles (DDGS) is used in livestock feeds and finishing diets to replace maize or other grains. As more of this product is available to the feed industry, the effect it might have on the vulnerability of animal feed to insect infestation is unknown. This research focused on the influence of old generation DDGS as food and oviposition resource of red flour beetle Tribolium castaneum in contrast with a traditional a flour (90%)/yeast (10%) diet. Larval development was significantly fasterKeywords: DDGS, Red flour beetle, Tribolium castaneum, Oviposition, Developmen
Flow around a cube in a turbulent boundary layer: LES and experiment
We present a numerical simulation of flow around a surface mounted cube placed in a turbulent boundary layer which, although representing a typical wind environment, has been specifically tailored to match a series of wind tunnel observations. The simulations were carried out at a Reynolds number, based on the velocity U at the cube height h, of 20,000—large enough that many aspects of the flow are effectively Reynolds number independent. The turbulence intensity was about 18% at the cube height, and the integral length scale was about 0.8 times the cube height h. The Jenson number Je=h/z0, based on the approach flow roughness length z0, was 600, to match the wind tunnel situation. The computational mesh was uniform with a spacing of h/32, aiding rapid convergence of the multigrid solver, and the governing equations were discretised using second-order finite differences within a parallel multiblock environment. The results presented include detailed comparison between measurements and LES computations of both the inflow boundary layer and the flow field around the cube including mean and fluctuating surface pressures. It is concluded that provided properly formulated inflow and surface boundary conditions are used, LES is now a viable tool for use in wind engineering problems concerning flow over isolated bodies. In particular, both mean and fluctuating surface pressures can be obtained with a similar degree of uncertainty as usually associated with wind tunnel modelling
Two Alternating Motor Programs Drive Navigation in Drosophila Larva
When placed on a temperature gradient, a Drosophila larva navigates away from excessive cold or heat by regulating the size, frequency, and direction of reorientation maneuvers between successive periods of forward movement. Forward movement is driven by peristalsis waves that travel from tail to head. During each reorientation maneuver, the larva pauses and sweeps its head from side to side until it picks a new direction for forward movement. Here, we characterized the motor programs that underlie the initiation, execution, and completion of reorientation maneuvers by measuring body segment dynamics of freely moving larvae with fluorescent muscle fibers as they were exposed to temporal changes in temperature. We find that reorientation maneuvers are characterized by highly stereotyped spatiotemporal patterns of segment dynamics. Reorientation maneuvers are initiated with head sweeping movement driven by asymmetric contraction of a portion of anterior body segments. The larva attains a new direction for forward movement after head sweeping movement by using peristalsis waves that gradually push posterior body segments out of alignment with the tail (i.e., the previous direction of forward movement) into alignment with the head. Thus, reorientation maneuvers during thermotaxis are carried out by two alternating motor programs: (1) peristalsis for driving forward movement and (2) asymmetric contraction of anterior body segments for driving head sweeping movement
Optimizing stored light efficiency in vapor cells
ABSTRACT We present a preliminary experimental study of slow and stored light in Rb vapor cells under the conditions of electromagnetically induced transparency (EIT). We study the efficiency of light storage as a function of pulse duration, storage time, retrieval field intensity, etc. We demonstrate that atomic diffusion in-and-out of the laser beam plays an important role not well described by previous analysis
"It never rains in California": constructions of drought as a natural and social phenomenon
In response to suggestions that, in the West, inaction on climate change is due to climate change’s perceived temporal and spatial distance, we examine how people in California responded to the local influence of climate change in relation to the California drought in 2015. Between 2012 and 2016 California experienced an exceptionally severe drought resulting in a variety of social impacts. In this paper, we focus on how people experienced and understood drought (rather than on their views on the connection between anthropogenic climate change and drought). Seventy-one interviews were conducted during ten weeks of fieldwork in late 2015 with people in urban and rural areas of California. Five emerging themes are discussed: (i) conceptions of normality, (ii) location (inside versus outside urban areas), (iii) emotional responses, (iv) understanding the drought as a social and political phenomenon, and (v) marginalised experiences of the drought. Examining perceptions of drought can enhance our understanding of how people react to climate change and the construction of proximity and personal relevance
Analysis of Serum Levels of Anti-Müllerian Hormone, Inhibin B, Insulin-Like Growth Factor-I, Insulin-Like Growth Factor Binding Protein-3, and Follicle-Stimulating Hormone with Respect to Age and Menopausal Status
This study was undertaken to investigate age-dependent and postmenopausal changes in the serum levels of anti-Müllerian hormone (AMH), inhibin B, insulin-like growth factor (IGF)-I, IGF-binding protein-3 (IGFBP-3), and follicle-stimulating hormone (FSH), and to determine which of these markers best reflects the aging process in women. A total of 144 women aged 20-59 yr were enrolled in this cross-sectional study. Blood samples were obtained on cycle day 3 of regularly menstruating women (n=111), or at random in postmenopausal women (n=33). Data were analyzed with respect to premenopausal women age groups and compared in pre- and postmenopausal women. Area under the receiver operating characteristic curve (ROCAUC) analyses were performed to assess the ability of each marker to discriminate between the pre- and postmenopausal status. Serum levels of AMH, IGF-I, and IGFBP-3 decreased and serum levels of FSH increased significantly with age in premenopausal women. Serum luteinizing hormone (LH) was higher and inhibin B was lower in women in their 20-30's than in 40's. Serum levels of AMH and IGF-I showed a consistent decrease with all age groups. ROCAUC analysis showed that the diagnostic accuracy of AMH for menopausal status was similar to those of FSH, LH, and inhibin B, and was better than that of IGF-I. In conclusion, the serum AMH level appears to be the best marker of the aging process in premenopausal women
Humans:the missing link in manufacturing simulation?
Computer based discrete event simulation (DES) is one of the most commonly used aids for the design of automotive manufacturing systems. However, DES tools represent machines in extensive detail, while only representing workers as simple resources. This presents a problem when modelling systems with a highly manual work content, such as an assembly line. This paper describes research at Cranfield University, in collaboration with the Ford Motor Company, founded on the assumption that human variation is the cause of a large percentage of the disparity between simulation predictions and real world performance. The research aims to improve the accuracy and reliability of simulation prediction by including models of human factors
Sprouty2 mediated tuning of signalling is essential for somite myogenesis
Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development. Sprouty2 (Spry2) negatively regulates receptor tyrosine kinases (RTK) and FGF signalling and is important in differentiation, cell migration and proliferation. In vertebrate embryos, Spry2 is expressed in paraxial mesoderm and in forming somites. Expression is maintained in the myotome until late stages of somite differentiation. However, its role and mode of action during somite myogenesis is still unclear. Results: Here, we analysed chick Spry2 expression and showed that it overlaps with that of myogenic regulatory factors MyoD and Mgn. Targeted mis-expression of Spry2 led to inhibition of myogenesis, whilst its C-terminal domain led to an increased number of myogenic cells by stimulating cell proliferation. Conclusions: Spry2 is expressed in somite myotomes and its expression overlaps with myogenic regulatory factors. Overexpression and dominant-negative interference showed that Spry2 plays a crucial role in regulating chick myogenesis by fine tuning of FGF signaling through a negative feedback loop. We also propose that mir-23, mir-27 and mir-128 could be part of the negative feedback loop mechanism. Our analysis is the first to shed some light on in vivo Spry2 function during chick somite myogenesis
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Synchronous and opponent thermosensors use flexible cross-inhibition to orchestrate thermal homeostasis.
Body temperature homeostasis is essential and reliant upon the integration of outputs from multiple classes of cooling- and warming-responsive cells. The computations that integrate these outputs are not understood. Here, we discover a set of warming cells (WCs) and show that the outputs of these WCs combine with previously described cooling cells (CCs) in a cross-inhibition computation to drive thermal homeostasis in larval Drosophila WCs and CCs detect temperature changes using overlapping combinations of ionotropic receptors: Ir68a, Ir93a, and Ir25a for WCs and Ir21a, Ir93a, and Ir25a for CCs. WCs mediate avoidance to warming while cross-inhibiting avoidance to cooling, and CCs mediate avoidance to cooling while cross-inhibiting avoidance to warming. Ambient temperature-dependent regulation of the strength of WC- and CC-mediated cross-inhibition keeps larvae near their homeostatic set point. Using neurophysiology, quantitative behavioral analysis, and connectomics, we demonstrate how flexible integration between warming and cooling pathways can orchestrate homeostatic thermoregulation
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