404 research outputs found
Collider signals from slow decays in supersymmetric models with an intermediate-scale solution to the mu problem
The problem of the origin of the mu parameter in the Minimal Supersymmetric
Standard Model can be solved by introducing singlet supermultiplets with
non-renormalizable couplings to the ordinary Higgs supermultiplets. The
Peccei-Quinn symmetry is broken at a scale which is the geometric mean between
the weak scale and the Planck scale, yielding a mu term of the right order of
magnitude and an invisible axion. These models also predict one or more singlet
fermions which have electroweak-scale masses and suppressed couplings to MSSM
states. I consider the case that such a singlet fermion, containing the axino
as an admixture, is the lightest supersymmetric particle. I work out the
relevant couplings in several of the simplest models of this type, and compute
the partial decay widths of the next-to-lightest supersymmetric particle
involving leptons or jets. Although these decays will have an average proper
decay length which is most likely much larger than a typical collider detector,
they can occasionally occur within the detector, providing a striking signal.
With a large sample of supersymmetric events, there will be an opportunity to
observe these decays, and so gain direct information about physics at very high
energy scales.Comment: 24 pages, LaTeX, 4 figure
The Neutralino Sector in the U(1)-Extended Supersymmetric Standard Model
Motivated by grand unified theories and string theories we analyze the
general structure of the neutralino sector in the USSM, an extension of the
Minimal Supersymmetric Standard Model that involves a broken extra U(1) gauge
symmetry. This supersymmetric U(1)-extended model includes an Abelian gauge
superfield and a Higgs singlet superfield in addition to the standard gauge and
Higgs superfields of the MSSM. The interactions between the MSSM fields and the
new fields are in general weak and the mixing is small, so that the coupling of
the two subsystems can be treated perturbatively. As a result, the mass
spectrum and mixing matrix in the neutralino sector can be analyzed
analytically and the structure of this 6-state system is under good theoretical
control. We describe the decay modes of the new states and the impact of this
extension on decays of the original MSSM neutralinos, including radiative
transitions in cross-over zones. Production channels in cascade decays at the
LHC and pair production at colliders are also discussed.Comment: 50 pages, 9 figures, equations.sty include
MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma
This study investigates the influence expression of the MYCN oncogene has on the DNA damage response, replication fork progression and sensitivity to PARP inhibition in neuroblastoma. In a panel of neuroblastoma cell lines, MYCN amplification or MYCN expression resulted in increased cell death in response to a range of PARP inhibitors (niraparib, veliparib, talazoparib and olaparib) compared to the response seen in non-expressing/amplified cells. MYCN expression slowed replication fork speed and increased replication fork stalling, an effect that was amplified by PARP inhibition or PARP1 depletion. Increased DNA damage seen was specifically induced in S-phase cells. Importantly, PARP inhibition caused a significant increase in the survival of mice bearing MYCN expressing tumours in a transgenic murine model of MYCN expressing neuroblastoma. Olaparib also sensitized MYCN expressing cells to camptothecin- and temozolomide-induced cell death to a greater degree than non-expressing cells. In summary, MYCN expression leads to increased replication stress in neuroblastoma cells. This effect is exaggerated by inhibition of PARP, resulting in S-phase specific DNA damage and ultimately increased tumour cell death. PARP inhibition alone or in combination with classical chemotherapeutics is therefore a potential therapeutic strategy for neuroblastoma and may be more effective in MYCN expressing tumours
Wedgebox analysis of four-lepton events from neutralino pair production at the LHC
`Wedgebox' plots constructed by plotting the di-electron invariant mass
versus the di-muon invariant mass from pp -> e^+e^- mu^+ mu^- + missing energy
signature LHC events. Data sets of such events are obtained across the MSSM
input parameter space in event-generator simulations, including cuts designed
to remove SM backgrounds. Their study reveals several general features:
(1)Regions in the MSSM input parameter space where a sufficient number of
events are expected so as to be able to construct a clear wedgebox plot are
delineated. (2)The presence of box shapes on a wedgebox plot either indicates
the presence of heavy Higgs bosons decays or restricts the location to a quite
small region of low \mu and M_2 values \lsim 200 GeV, a region denoted as the
`lower island'. In this region, wedgebox plots can be quite complicated and
change in pattern rather quickly as one moves around in the (\mu, M_2) plane.
(3)Direct neutralino pair production from an intermediate Z^{0*} may only
produce a wedge-shape since only \widetilde{\chi}_2^0\widetilde{\chi}_3^0
decays can contribute significantly. (4)A double-wedge or
wedge-protruding-from-a-box pattern on a wedgebox plot, which results from
combining a variety of MSSM production processes, yields three distinct
observed endpoints, almost always attributable to \widetilde{\chi}_{2,3,4}^0
\to \widetilde{\chi}_1^0 \ell^+\ell^- decays, which can be utilized to
determine a great deal of information about the neutralino and slepton mass
spectra and related MSSM input parameters. Wedge and double-wedge patterns are
seen in wedgebox plots in another region of higher \mu and M_2 values, denoted
as the`upper island.' Here the pattern is simpler and more stable as one moves
across the (\mu, M_2) input parameter space.Comment: 28 pages (LaTeX), 8 figures (encapsulated postscript
What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey
Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving the quality of life of older adults. The ageing in place literature suggests that policies in other functions of local authorities may have a significant role to play. This study aims to examine the associations between social care-related quality of life (SCRQoL) in older adults and three potential policy targets for local authorities: (i) accessibility of information and advice, (ii) design of the home and (iii) accessibility of the local area. We used cross-sectional data from the English national Adult Social Care Survey (ASCS) 2010/2011 on service users aged 65 years and older and living at home (N=29,935). To examine the association between SCRQoL, as measured by the ASCOT, and three single-item questions about accessibility of information, design of the home and accessibility of the local area, we estimate linear and quantile regression models. After adjusting for physical and mental health factors and other confounders our findings indicate that SCRQoL is significantly lower for older adults who find it more difficult to find information and advice, for those who report that their home design is inappropriate for their needs and for those who find it more difficult to get around their local area. In addition, these three variables are as strongly associated with SCRQoL as physical and mental health factors. We conclude that in seeking to find ways to maintain and improve the quality of life of social care users living at home, local authorities could look more broadly across their responsibilities. Further research is required to explore the cost-effectiveness of these options compared to standard social care services
Higgs Scalars in the Minimal Non-minimal Supersymmetric Standard Model
We consider the simplest and most economic version among the proposed
non-minimal supersymmetric models, in which the -parameter is promoted to
a singlet superfield, whose all self-couplings are absent from the
renormalizable superpotential. Such a particularly simple form of the
renormalizable superpotential may be enforced by discrete -symmetries which
are extended to the gravity-induced non-renormalizable operators as well. We
show explicitly that within the supergravity-mediated supersymmetry-breaking
scenario, the potentially dangerous divergent tadpoles associated with the
presence of the gauge singlet first appear at loop levels higher than 5 and
therefore do not destabilize the gauge hierarchy. The model provides a natural
explanation for the origin of the -term, without suffering from the
visible axion or the cosmological domain-wall problem. Focusing on the Higgs
sector of this minimal non-minimal supersymmetric standard model, we calculate
its effective Higgs potential by integrating out the dominant quantum effects
due to stop squarks. We then discuss the phenomenological implications of the
Higgs scalars predicted by the theory for the present and future high-energy
colliders. In particular, we find that our new minimal non-minimal
supersymmetric model can naturally accommodate a relatively light charged Higgs
boson, with a mass close to the present experimental lower bound.Comment: 63 pages (12 figures), extended versio
Implications of a Massless Neutralino for Neutrino Physics
We consider the phenomenological implications of a soft SUSY breaking term BN
at the TeV scale (here B is the U(1)_Y gaugino and N is the right-handed
neutrino field). In models with a massless (or nearly massless) neutralino,
such a term will give rise through the see-saw mechanism to new contributions
to the mass matrix of the light neutrinos.
We treat the massless neutralino as an (almost) sterile neutrino and find
that its mass depends on the square of the soft SUSY breaking scale, with
interesting consequences for neutrino physics. We also show that, although it
requires fine-tuning, a massless neutralino in the MSSM or NMSSM is not
experimentally excluded. The implications of this scenario for neutrino physics
are discussed.Comment: 14 pages, latex, no figure
Dynamic nuclear polarization and spin-diffusion in non-conducting solids
There has been much renewed interest in dynamic nuclear polarization (DNP),
particularly in the context of solid state biomolecular NMR and more recently
dissolution DNP techniques for liquids. This paper reviews the role of spin
diffusion in polarizing nuclear spins and discusses the role of the spin
diffusion barrier, before going on to discuss some recent results.Comment: submitted to Applied Magnetic Resonance. The article should appear in
a special issue that is being published in connection with the DNP Symposium
help in Nottingham in August 200
Non-Minimal Supersymmetric Higgs Bosons at LEP2
We discuss the discovery reach of LEP2 for the Higgs sector of a general
extension of the MSSM including a single gauge singlet field. This change
introduces a new quartic Higgs boson self-coupling which can increase the
masses of the CP-even states, and also allows mixing between singlet and
non-singlet states which can reduce the couplings of the mass eigenstates to
the . The lightest CP-even Higgs boson is bounded by a parameter
which takes a maximum value GeV for top mass
GeV. We generalise the discussion of the bound to include the entire
CP-even spectrum and show how experiment may exclude values of
smaller than some . CP-even Higgs boson searches at LEP2 will be
able to exclude GeV, depending on the machine
parameters. We also present exclusion plots in the plane, based
on an analysis of CP-even, CP-odd and charged Higgs production processes at
LEP2.Comment: Plain LaTeX, 33 pages, figures uuencoded and gzipped. Trivial changes
and typos corrected for publication in Rhys Rev
Charged lepton Flavor Violation in Supersymmetry with Bilinear R-Parity Violation
The simplest unified extension of the Minimal Supersymmetric Standard Model
with bi-linear R-parity violation naturally predicts a hierarchical neutrino
mass spectrum, suitable to explain atmospheric and solar neutrino fluxes. We
study whether the individual violation of the lepton numbers L_{e,mu,tau} in
the charged sector can lead to measurable rates for BR(mu->e gamma)and
$BR(tau-> mu gamma). We find that some of the R-parity violating terms that are
compatible with the observed atmospheric neutrino oscillations could lead to
rates for mu->e gamma measurable in projected experiments. However, the Delta
m^2_{12} obtained for those parameters is too high to be compatible with the
solar neutrino data, excluding therefore the possibility of having measurable
rates for mu->e gamma in the model.Comment: 29 pages, 8 figures. Constraint from solar neutrino data included,
conclusions changed respect v
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