131 research outputs found
Search for the exotic resonance in the NOMAD experiment
A search for exotic Theta baryon via Theta -> proton +Ks decay mode in the
NOMAD muon neutrino DIS data is reported. The special background generation
procedure was developed. The proton identification criteria are tuned to
maximize the sensitivity to the Theta signal as a function of xF which allows
to study the Theta production mechanism. We do not observe any evidence for the
Theta state in the NOMAD data. We provide an upper limit on Theta production
rate at 90% CL as 2.13 per 1000 of neutrino interactions.Comment: Accepted to European Physics Journal
Search for nu(mu)-->nu(e) Oscillations in the NOMAD Experiment
We present the results of a search for nu(mu)-->nu(e) oscillations in the
NOMAD experiment at CERN. The experiment looked for the appearance of nu(e) in
a predominantly nu(mu) wide-band neutrino beam at the CERN SPS. No evidence for
oscillations was found. The 90% confidence limits obtained are delta m^2 < 0.4
eV^2 for maximal mixing and sin^2(2theta) < 1.4x10^{-3} for large delta m^2.
This result excludes the LSND allowed region of oscillation parameters with
delta m^2 > 10 eV^2.Comment: 19 pages, 8 figures. Submitted to Phys. Lett.
A Precise Measurement of the Muon Neutrino-Nucleon Inclusive Charged Current Cross-Section off an Isoscalar Target in the Energy Range 2.5 < E_\nu < 40 GeV by NOMAD
We present a measurement of the muon neutrino-nucleon inclusive charged
current cross-section, off an isoscalar target, in the neutrino energy range
GeV. The significance of this measurement is its
precision, % in GeV, and % in GeV regions, where significant uncertainties in previous
experiments still exist, and its importance to the current and proposed long
baseline neutrino oscillation experiments.Comment: 14 pages, 3 figures, submitted to Phys.Lett.
A Study of Strange Particles Produced in Neutrino Neutral Current Interactions in the NOMAD Experiment
Results of a detailed study of strange particle production in neutrino
neutral current interactions are presented using the data from the NOMAD
experiment. Integral yields of neutral strange particles (K0s, Lambda,
Lambda-bar) have been measured. Decays of resonances and heavy hyperons with an
identified K0s or Lambda in the final state have been analyzed. Clear signals
corresponding to K* and Sigma(1385) have been observed. First results on the
measurements of the Lambda polarization in neutral current interactions have
been obtained.Comment: Accepted for publication in Nuclear Physics B as a rapid
communicatio
A Measurement of Coherent Neutral Pion Production in Neutrino Neutral Current Interactions in NOMAD
We present a study of exclusive neutral pion production in neutrino-nucleus
Neutral Current interactions using data from the NOMAD experiment at the CERN
SPS. The data correspond to muon-neutrino Charged Current
interactions in the energy range GeV. Neutrino
events with only one visible in the final state are expected to result
from two Neutral Current processes: coherent production, {\boldmath
} and single production in
neutrino-nucleon scattering. The signature of coherent production is an
emergent almost collinear with the incident neutrino while 's
produced in neutrino-nucleon deep inelastic scattering have larger transverse
momenta. In this analysis all relevant backgrounds to the coherent
production signal are measured using data themselves. Having determined the
backgrounds, and using the Rein-Sehgal model for the coherent
production to compute the detection efficiency, we obtain {\boldmath } corrected coherent- events with GeV. We measure {\boldmath }.
This is the most precise measurement of the coherent production to
date.Comment: 23 pages, 9 figures, accepted for publication in Phys. Lett.
Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: A pharmacogenomics study from the CHARGE consortium
Background Hypertension is a major risk factor for a spectrum of cardiovascular diseases (CVD), including myocardial infarction, sudden death, and stroke. In the US, over 65 million people have high blood pressure and a large proportion of these individuals are prescribed antihypertensive medications. Although large long-term clinical trials conducted in the last several decades have identified a number of effective antihypertensive treatments that reduce the risk of future clinical complications, responses to therapy and protection from cardiovascular events vary among individuals. Methods Using a genome-wide association study among 21,267 participants with pharmaceutically treated hypertension, we explored the hypothesis that genetic variants might influence or modify the effectiveness of common antihypertensive therapies on the risk ofmajor cardiovascular outcomes. The classes of drug treatments included angiotensin-converting enzyme inhibitors, beta-blockers, calcium channel blockers, and diuretics. In the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, each study performed array-based genome-wide genotyping, imputed to HapMap Phase II reference panels, and used additive genetic models in proportional hazards or logistic regressionmodels to evaluate drug-gene interactions for each of four therapeutic drug classes. We used meta-analysis to combine study-specific interaction estimates for approximately 2 million single nucleotide polymorphisms (SNPs) in a discovery analysis among 15,375 European Ancestry participants (3,527 CVD cases) with targeted follow-up in a case-only study of 1,751 European Ancestry GenHAT participants as well as among 4,141 African-Americans (1,267 CVD cases). Results Although drug-SNP interactions were biologically plausible, exposures and outcomes were well measured, and power was sufficient to detect modest interactions, we did not identify any statistically significant interactions from the four antihypertensive therapy meta-analyses (Pinteraction > 5.0×10-8). Similarly, findings were null for meta-analyses restricted to 66 SNPs with significant main effects on coronary artery disease or blood pressure from large published genom
The ‘mosaic habitat’ concept in human evolution: past and present
The habitats preferred by hominins and other species are an important theme in palaeoanthropology, and the ‘mosaic habitat’ (also referred to as habitat heterogeneity) has been a central concept in this regard for the last four decades. Here we explore the development of this concept – loosely defined as a range of different habitat types, such as woodlands, riverine forest and savannah within a limited spatial area– in studies of human evolution in the last sixty years or so. We outline the key developments that took place before and around the time when the term ‘mosaic’ came to wider palaeoanthropological attention. To achieve this we used an analysis of the published literature, a study of illustrations of hominin evolution from 1925 onwards and an email survey of senior researchers in palaeoanthropology and related fields. We found that the term mosaic starts to be applied in palaeoanthropological thinking during the 1970’s due to the work of a number of researchers, including Karl Butzer and Glynn Isaac , with the earliest usage we have found of ‘mosaic’ in specific reference to hominin habitats being by Adriaan Kortlandt (1972). While we observe a steady increase in the numbers of publications reporting mosaic palaeohabitats, in keeping with the growing interest and specialisation in various methods of palaeoenvironmental reconstruction, we also note that there is a lack of critical studies that define this habitat, or examine the temporal and spatial scales associated with it. The general consensus within the field is that the concept now requires more detailed definition and study to evaluate its role in human evolution
Bose-Einstein correlations in charged current muon-neutrino interactions in the NOMAD experiment at CERN
Bose-Einstein correlations in one and two dimensions have been studied, with high statistics, in charged current muon-neutrino interaction events collected with the NOMAD detector at CERN. In one dimension the Bose-Einstein effect has been analyzed with the Goldhaber and the Kopylov-Podgoretskii phenomenological parametrizations. The Goldhaber parametrization gives the radius of the pion emission region R-G = 1.01 +/- 0.05(stat)(-0.06)(+0,09)(sys) fm and for the chaoticity parameter the value lambda = 0.40 +/- 0.03(stat)(-0.06)(+0.01) (sys). Using the Kopylov-Podgoretskii parametrization yields R-KP = 2.07 +/- 0.04(stat)(-0.14)(+0.01) (sys) fm and lambda(KP) = 0.29 +/- 0.06(stat)(-0.04)(+0,01) (sys) Different parametrizations of the long-range correlations have been also studied. The two-dimensional shape of the source has been investigated in the longitudinal comoving frame. A significant difference between the transverse and the longitudinal dimensions is observed. The high statistics of the collected sample allowed the study of the Bose-Einstein correlations as a function of rapidity, charged particle multiplicity and hadronic energy. A weak dependence of both radius and chaoticity on multiplicity and hadronic energy is found
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