96 research outputs found

    Uncertainties in climate change projections and regional downscaling: implications for water resources management

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    Climate change is expected to have a large impact on water resources worldwide. A major problem in assessing the potential impact of a changing climate on these resources is the difference in spatial scale between available climate change projections and water resources management. Regional climate models (RCMs) are often used for the spatial disaggregation of the outputs of global circulation models. However, RCMs are time-intensive to run and typically only a small number of model runs is available for a certain region of interest. This paper investigates the value of the improved representation of local climate processes by a regional climate model for water resources management in the tropical Andes of Ecuador. This region has a complex hydrology and its water resources are under pressure. Compared to the IPCC AR4 model ensemble, the regional climate model PRECIS does indeed capture local gradients better than global models, but locally the model is prone to large discrepancies between observed and modelled precipitation. It is concluded that a further increase in resolution is necessary to represent local gradients properly. Furthermore, to assess the uncertainty in downscaling, an ensemble of regional climate models should be implemented. Finally, translating the climate variables to streamflow using a hydrological model constitutes a smaller but not negligible source of uncertainty

    Treatment of Polarographic Data by the Method of Least-squares. II. Simultaneous Estimation of the Diffusion Current and the Half-wave Potential

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    By applying the method of least squares it is possible to estimate simultaneously the diffusion current and the half-wave potential with precision which exceeds that of the usual graphical methods. The method described in this paper is particularly suitable for analysing composite current-voltage curves. An example is given of the analysis of the composite curve obtained with a solution containing thallous and lead ions in 0.1 N KC

    Daily Patterns of River Herring (\u3cem\u3eAlosa\u3c/em\u3e spp.) Spawning Migrations: Environmental Drivers and Variation among Coastal Streams in Massachusetts

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    The timing of life history events in many plants and animals depends on the seasonal fluctuations of specific environmental conditions. Climate change is altering environmental regimes and disrupting natural cycles and patterns across communities. Anadromous fishes that migrate between marine and freshwater habitats to spawn are particularly sensitive to shifting environmental conditions and thus are vulnerable to the effects of climate change. However, for many anadromous fish species the specific environmental mechanisms driving migration and spawning patterns are not well understood. In this study, we investigated the upstream spawning migrations of river herring Alosa spp. in 12 coastal Massachusetts streams. By analyzing long-term data sets (8–28 years) of daily fish counts, we determined the local influence of environmental factors on daily migration patterns and compared seasonal run dynamics and environmental regimes among streams. Our results suggest that water temperature was the most consistent predictor of both daily river herring presence–absence and abundance during migration. We found inconsistent effects of streamflow and lunar phase, likely due to the anthropogenic manipulation of flow and connectivity in different systems. Geographic patterns in run dynamics and thermal regimes suggest that the more northerly runs in this region are relatively vulnerable to climate change due to migration occurring later in the spring season, at warmer water temperatures that approach thermal maxima, and during a narrower temporal window compared to southern runs. The phenology of river herring and their reliance on seasonal temperature patterns indicate that populations of these species may benefit from management practices that reduce within-stream anthropogenic water temperature manipulations and maintain coolwater thermal refugia

    A call to action for climate change research on Caribbean dry forests

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    The final publication is available at Springer via https://doi.org/10.1007/s10113-018-1334-6Tropical dry forest (TDF) is globally one of the most threatened forest types. In the insular Caribbean, limited land area and high population pressure have resulted in the loss of over 60% of TDF, yet local people’s reliance on these systems for ecosystem services is high. Given the sensitivity of TDF to shifts in precipitation regimes and the vulnerability of the Caribbean to climate change, this study examined what is currently known about the impacts of climate change on TDF in the region. A systematic review (n = 89) revealed that only two studies addressed the ecological response of TDF to climate change. Compared to the rapidly increasing knowledge of the effects of climate change on other Caribbean systems and on TDF in the wider neotropics, this paucity is alarming given the value of these forests. We stress the need for long-term monitoring of climate change responses of these critical ecosystems, including phenological and hotspot analyses as priorities

    Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

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    Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline

    Large-scale climatic phenomena drive fluctuations in macroinvertebrate assemblages in lowland tropical streams, Costa Rica: The importance of ENSO events in determining long-term (15y) patterns

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    Understanding how environmental variables influence the distribution and density of organisms over relatively long temporal scales is a central question in ecology given increased climatic variability (e.g., precipitation, ENSO events). The primary goal of our study was to evaluate long-term (15y time span) patterns of climate, as well as environmental parameters in two Neotropical streams in lowland Costa Rica, to assess potential effects on aquatic macroinvertebrates. We also examined the relative effects of an 8y whole-stream P-enrichment experiment on macroinvertebrate assemblages against the backdrop of this long-term study. Climate, environmental variables and macroinvertebrate samples were measured monthly for 7y and then quarterly for an additional 8y in each stream. Temporal patterns in climatic and environmental variables showed high variability over time, without clear inter-annual or intra-annual patterns. Macroinvertebrate richness and abundance decreased with increasing discharge and was positively related to the number of days since the last high discharge event. Findings show that fluctuations in stream physicochemistry and macroinvertebrate assemblage structure are ultimately the result of large-scale climatic phenomena, such as ENSO events, while the 8y P-enrichment did not appear to affect macroinvertebrates. Our study demonstrates that Neotropical lowland streams are highly dynamic and not as stable as is commonly presumed, with high intra- and inter-annual variability in environmental parameters that change the structure and composition of freshwater macroinvertebrate assemblages.This study was financed by National Science Foundation (DEB 1122389) to Catherine M. Pringle. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Ciencias del Mar y Limnología (CIMAR

    Dynamical downscaling of historical climate over CORDEX Central America domain with a regionally coupled atmosphere–ocean model

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    The climate in Mexico and Central America is influenced by the Pacific and the Atlantic oceanic basins and atmospheric conditions over continental North and South America. These factors and important ocean–atmosphere coupled processes make the region’s climate a great challenge for global and regional climate modeling. We explore the benefits that coupled regional climate models may introduce in the representation of the regional climate with a set of coupled and uncoupled simulations forced by reanalysis and global model data. Uncoupled simulations tend to stay close to the large-scale patterns of the driving fields, particularly over the ocean, while over land they are modified by the regional atmospheric model physics and the improved orography representation. The regional coupled model adds to the reanalysis forcing the air–sea interaction, which is also better resolved than in the global model. Simulated fields are modified over the ocean, improving the representation of the key regional structures such as the Intertropical Convergence Zone and the Caribbean Low Level Jet. Higher resolution leads to improvements over land and in regions of intense air–sea interaction, e.g., off the coast of California. The coupled downscaling improves the representation of the Mid Summer Drought and the meridional rainfall distribution in southernmost Central America. Over the regions of humid climate, the coupling corrects the wet bias of the uncoupled runs and alleviates the dry bias of the driving model, yielding a rainfall seasonal cycle similar to that in the reanalysis-driven experiments.Universidad de Costa Rca/[805-B7-507]/UCR/Costa RicaCRYOPERU/[144-2015]//PerúUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones Geofísicas (CIGEFI
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