154 research outputs found

    Toward an understanding of risk factors for binge-eating disorder in black and white women: A community-based case-control study

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    This study sought to identify in white women risk factors specific to binge-eating disorder (BED) and for psychiatric disorders in general, and to compare black and white women on risk factors for BED.

    Circumstellar Structure around Evolved Stars in the Cygnus-X Star Formation Region

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    We present observations of newly discovered 24 micron circumstellar structures detected with the Multiband Imaging Photometer for Spitzer (MIPS) around three evolved stars in the Cygnus-X star forming region. One of the objects, BD+43 3710, has a bipolar nebula, possibly due to an outflow or a torus of material. A second, HBHA 4202-22, a Wolf-Rayet candidate, shows a circular shell of 24 micron emission suggestive of either a limb-brightened shell or disk seen face-on. No diffuse emission was detected around either of these two objects in the Spitzer 3.6-8 micron Infrared Array Camera (IRAC) bands. The third object is the luminous blue variable candidate G79.29+0.46. We resolved the previously known inner ring in all four IRAC bands. The 24 micron emission from the inner ring extends ~1.2 arcmin beyond the shorter wavelength emission, well beyond what can be attributed to the difference in resolutions between MIPS and IRAC. Additionally, we have discovered an outer ring of 24 micron emission, possibly due to an earlier episode of mass loss. For the two shell stars, we present the results of radiative transfer models, constraining the stellar and dust shell parameters. The shells are composed of amorphous carbon grains, plus polycyclic aromatic hydrocarbons in the case of G79.29+0.46. Both G79.29+0.46 and HBHA 4202-22 lie behind the main Cygnus-X cloud. Although G79.29+0.46 may simply be on the far side of the cloud, HBHA 4202-22 is unrelated to the Cygnus-X star formation region.Comment: Accepted by A

    A Post-AGB Star in the Small Magellanic Cloud Observed with the Spitzer Infrared Spectrograph

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    We have observed an evolved star with a rare combination of spectral features, MSX SMC 029, in the Small Magellanic Cloud (SMC) using the low-resolution modules of the Infrared Spectrograph on the Spitzer Space Telescope. A cool dust continuum dominates the spectrum of MSX SMC 029. The spectrum also shows both emission from polycyclic aromatic hydrocarbons (PAHs) and absorption at 13.7 micron from C2H2, a juxtaposition seen in only two other sources, AFGL 2688 and IRAS 13416-6243, both post-asymptotic giant branch (AGB) objects. As in these sources, the PAH spectrum has the unusual trait that the peak emission in the 7-9 micron complex lies beyond 8.0 micron. In addition, the 8.6 micron feature has an intensity as strong as the C-C modes which normally peak between 7.7 and 7.9 micron. The relative flux of the feature at 11.3 micron to that at 8 micron suggests that the PAHs in MSX SMC 029 either have a low ionization fraction or are largely unprocessed. The 13-16 micron wavelength region shows strong absorption features similar to those observed in the post-AGB objects AFGL 618 and SMP LMC 11. This broad absorption may arise from the same molecules which have been identified in those sources: C2H2, C4H2, HC3N, and C6H6. The similarities between MSX SMC 029, AFGL 2688, and AFGL 618 lead us to conclude that MSX SMC 029 has evolved off the AGB in only the past few hundred years, making it the third post-AGB object identified in the SMC.Comment: 4 figures, Fig. 4 color; to appear in the 20 November 2006 Astrophysical Journal Letter

    R CrB Candidates in the Small Magellanic Cloud: Observations of Cold, Featureless Dust with the Spitzer Infrared Spectrograph

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    We observed 36 evolved stars in the Small Magellanic Cloud (SMC) using the low-resolution mode of the Infrared Spectrograph (IRS) on the Spitzer Space Telescope. Two of these stars, MSX SMC 014 and 155, have nearly featureless spectral energy distributions over the IRS wavelength range (5.2-35 um) and F_nu peaking at ~8-9 um. The data can be fit by sets of amorphous carbon shells or by single 600-700 K blackbodies. The most similar spectra found in extant spectral databases are of R CrB, although the spectral structure seen in R CrB and similar stars is much weaker or absent in the SMC sources. Both SMC stars show variability in the near-infrared. Ground-based visual spectra confirm that MSX SMC 155 is carbon-rich, as expected for R CrB (RCB) stars, and coincides with an object previously identified as an RCB candidate. The temperature of the underlying star is lower for MSX SMC 155 than for typical RCB stars. The strength of the C_2 Swan bands and the low temperature suggest that it may be a rare DY Per-type star, only the fifth such identified. MSX SMC 014 represents a new RCB candidate in the SMC, bringing the number of RCB candidates in the SMC to six. It is the first RCB candidate discovered with Spitzer and the first identified by its infrared spectral characteristics rather than its visual variability.Comment: Accepted by ApJ Letters 25 August, 2005, 4 pages (emulateapj), 5 figure

    SMC-Last Extracted Photometry

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    We present point-source photometry from the Spitzer Space Telescope's final survey of the Small Magellanic Cloud (SMC). We mapped nearly 30 deg2 in two epochs in 2017, with the second extending to early 2018 at 3.6 and 4.5 μm using the Infrared Array Camera. This survey duplicates the footprint from the SAGE-SMC program in 2008. Together, these surveys cover a nearly 10 yr temporal baseline in the SMC. We performed aperture photometry on the mosaicked maps produced from the new data. We did not use any prior catalogs as inputs for the extractor in order to be sensitive to any moving objects (e.g., foreground brown dwarfs) and other transient phenomena (e.g., cataclysmic variables or FU Ori–type eruptions). We produced a point-source catalog with high-confidence sources for each epoch as well as a combined-epoch catalog. For each epoch and the combined-epoch data, we also produced a more complete archive with lower-confidence sources. All of these data products will be made available to the community at the Infrared Science Archive

    miTuner - a kit for microRNA based gene expression tuning in mammalian cells

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    The purpose of this RFC is to introduce a modular expression tuning kit for use in mammalian cells. The kit enables the regulation of the gene expression of any gene of interest (GOI) based on synthetic microRNAs, endogenous microRNAs or a combination of both

    Global yellow fever vaccination coverage from 1970 to 2016: an adjusted retrospective analysis.

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    BACKGROUND: Substantial outbreaks of yellow fever in Angola and Brazil in the past 2 years, combined with global shortages in vaccine stockpiles, highlight a pressing need to assess present control strategies. The aims of this study were to estimate global yellow fever vaccination coverage from 1970 through to 2016 at high spatial resolution and to calculate the number of individuals still requiring vaccination to reach population coverage thresholds for outbreak prevention. METHODS: For this adjusted retrospective analysis, we compiled data from a range of sources (eg, WHO reports and health-service-provider registeries) reporting on yellow fever vaccination activities between May 1, 1939, and Oct 29, 2016. To account for uncertainty in how vaccine campaigns were targeted, we calculated three population coverage values to encompass alternative scenarios. We combined these data with demographic information and tracked vaccination coverage through time to estimate the proportion of the population who had ever received a yellow fever vaccine for each second level administrative division across countries at risk of yellow fever virus transmission from 1970 to 2016. FINDINGS: Overall, substantial increases in vaccine coverage have occurred since 1970, but notable gaps still exist in contemporary coverage within yellow fever risk zones. We estimate that between 393·7 million and 472·9 million people still require vaccination in areas at risk of yellow fever virus transmission to achieve the 80% population coverage threshold recommended by WHO; this represents between 43% and 52% of the population within yellow fever risk zones, compared with between 66% and 76% of the population who would have required vaccination in 1970. INTERPRETATION: Our results highlight important gaps in yellow fever vaccination coverage, can contribute to improved quantification of outbreak risk, and help to guide planning of future vaccination efforts and emergency stockpiling. FUNDING: The Rhodes Trust, Bill & Melinda Gates Foundation, the Wellcome Trust, the National Library of Medicine of the National Institutes of Health, the European Union's Horizon 2020 research and innovation programme
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