Black-glazed ware in ancient Caura

En este artículo presentamos el primer estudio realizado sobre cerámica fina de barniz negro procedente de la antigua Caura (Coria del Río, Sevilla, España). La cronología de los materiales abarca un período comprendido entre la segunda mitad del siglo V y el siglo I a.C. Se estudian tanto las importaciones procedentes de Grecia (Ática) e Italia (Campania, Toscana, entorno de Nápoles y Sicilia) como los productos del Mediterráneo occidental.We present in this paper the very first study on black-glazed fine ware from the ancient Caura (Coria Del Río, Seville, Spain). The research object materials chronology goes from the second half of the Vth century to Ist century BC. We analyze the imported wares from Greece (Attica) and Italy (Campania, Tuscany, Naples hinterland and Sicily), and also the western Mediterranean ones

Development and preliminary results of a mobile application to perform pre-inspection of sprayer equipment

Por todos es conocido que el presente y futuro de las aplicaciones de productos agroquímicos pasa por una buena regulación, calibración y mantenimiento de los equipos que se utilizan. Tanto Europa como los países miembros y sus comunidades autónomas, en el caso de España, a través de sus instituciones (Universidades, Consejerías, etc.), están trabajando concienzudamente en el protocolo de inspección. Es de prever que en muchos equipos la primera inspección será desfavorable, y además supondrá un coste económico alto para el propietario, independientemente de que el equipo pase la inspección de forma favorable o no. Este hecho hace que el agricultor no conciba este control con la “percepción beneficiosa” que pueda tener la administración. Por todo ello, el Laboratorio de Agricultura de Precisión de la Universidad de Sevilla ha decidido centrarse en el término “pre-inspección” y desarrollar una aplicación gratuita de autocontrol para dispositivos móviles que permita al propietario o su técnico agrícola conocer el estado de su equipo de aplicación antes de acudir a una inspección “oficial” y de esta forma solventar los posibles problemas detectados. En los primeros equipos que han formado parte de este estudio se ha conseguido, por una parte poner en conocimiento y mostrar los elementos y aspectos a controlar y por otra, generar de forma gratuita y fácil un informe donde se indica los elementos y aspectos a solventar antes de ir a una inspección. Esta aplicación de pre-inspección ha sido una herramienta muy valorada por los usuarios como mantenimiento preventivo.It is widely acknowledged that the present and future practice of pesticide applications requires good regulation, calibration and maintenance of the equipment used. European countries and their regional governments, in the case of Spain, through its institutions (Universities, Councils, etc.), are working conscientiously towards inspection protocol. It is expected that many sprayers will not pass the first inspection, and there will be a significant cost to the owner, whether the equipment passes the inspection or not. This fact makes this inspection protocol is not conceived with the “beneficial perception” as the administration may have. Therefore, the Precision Agriculture Laboratory at University of Sevilla has decided to focus on the term “pre-inspection” and develop a free mobile application for self-assessment that allows the owner or agricultural technician check the status of the sprayer before inspection. This would address the possible problem idenfified. For the first spayers considered in this study there have been several achievements: firstly informing about and showing those elements and aspects of the sprayer which need to be controlled and secondly, generating simply and without cost a report describing those elements and aspects which must be resolved before going for an inspection. This approach to pre-inspection has proved to be highly very valued by users as a tool for preventive maintenance

FÍMOSIS. REVISIÓN BIBLIOGRÁFICA. 2008.

La fimosis es bastante frecuente, sobre todo en niños, antes de la adolescencia. Se estima que sólo menos del 2% de los adolescentes de 17 años padecen fimosis. En el 95% de los recién nacidos es difícil la retracción prepucial. A los 6 meses sólo el 20% de los prepucios son retráctiles, al año el 50% son retráctiles y a los 3 años el 90% son retráctiles.La fimosis es bastante frecuente, sobre todo en niños, antes de la adolescencia. Se estima que sólo menos del 2% de los adolescentes de 17 años padecen fimosis. En el 95% de los recién nacidos es difícil la retracción prepucial. A los 6 meses sólo el 20% de los prepucios son retráctiles, al año el 50% son retráctiles y a los 3 años el 90% son retráctiles

Residuos de productos lácteos y de grasa de carne en dos recipientes cerámicos de la Edad del Bronce del Valle Medio del Duero

A través de análisis por cromatografía de gases-espectrometría de masas y del estudio de las reacciones inmunoquímicas de la caseína, se ha logrado identificar el residuo de sendos vasos cerámicos del horizonte inicial de Cogotas I de la provincia de Valladolid: un preparado de leche con cereales y grasa de carne. A partir de ahí, se insiste en la importancia de la actividad ganadera entre las comunidades del Bronce Medio de la Meseta y se considera, asimismo, la posibilidad de que el contenido de tales vasijas "completas" representara una ofrenda entre tantas otras atestiguadas en los "campos de hoyos" cogotianos.Through the application of Gas Chromatography-Mass Spectrometry and the determination of casein based on its immunochemical reactions, residues of animal fats and dairy products have been detected in two Bronze Age (Early Cogotas I culture) pottery vessels from Valladolid. The importance of cattle raising activities among the Middle Bronze Age societies of the Spanish Meseta is assessed here. It is argued that the original contents deposited in these vessels may have been offerings, as is the case with other materials that are found in the Cogotas I pit fields

Ecological quality assessement of marinas: An integrative approach combining biological and environmental data

The importance of marinas as infrastructures for recreational boating is increasing substantially. However, information on their soft-bottom benthic communities, a key tool for managing programmes, is still scarce. We combined environment features with macro- and meiofaunal soft-bottom community information for assessing the ecological status of marinas with an integrative approach. To address this issue, we focused on eight marinas of the Southern Iberian Peninsula. Macro- and meiofauna data revealed high benthic heterogeneity at a spatial scale. The environmental variables which correlated best with macrofauna were mainly phosphorus, granulometry, and total organic carbon, and secondarily important variables were faecal coliforms, the biocide Irgarol, and heavy metals; total hydrocarbon concentration was also significant for meiofauna. Annelida was the dominant phylum in terms of number of species (37%) and abundance (66%) and were better descriptors of the environmental conditions than Arthropoda and Mollusca. Although identification to the species level is desirable and mandatory for assessing biological pollution, significant differences among marinas and correlations between fauna and abiotic variables were already detected at the level of family and order. This implies that biota assessment at higher levels may still be useful in monitoring programmes limited by time and budget constraints. The major novelty of this study lies in the development of an integrative assessment method based on the following selected ecological indicators: Marinas Environmental Pollution Index (MEPI), Biocontamination Index (BCI), macrofaunal biotic indices (AMBI, M-AMBI, BENTIX, MEDOCC and BENFES), macrofaunal taxa richness and Shannon-Wiener's diversity, and nematode:copepod index. This approach was able to discriminate marinas of the Southern Iberian Peninsula based on their ecological status, which ranged from poor to good. The method can be useful to design standards for assigning “sustainable quality seals” to those marinas with better values of ecological indicators.Financial support for this study was provided by the Ministerio de Ciencia, Innovación y Universidades (Project CGL 2017-82739-P co-financed by the Agencia Estatal de Investigación -AEI- and Fondo Europeo de Desarrollo Regional - FEDER-)

Efecto del manejo del pastoreo racional en la capacidad de carga de Brachiaria humidicola en secano sin fertilización

The effect of Voisin restricted grazing and  portion grazing upon indexes determining load capacity of Brachiaria  humidicola cv. CIAT 679 without watering and fertilizing was evaluated for 4 years on a Vertisol soil in Cauto valley. 40 cows 5/8 Holstein- 3/8 Zebu were sampled by a completely randomized design. Grazing was done “in line” using cattle yards with the same size for Voisin restricted grazing, and grazing strips for  portion grazing in which each herd fed daily out of a strip according to its avail- ability in order to increase maximum grazing consumption. Strip management in  portion grazing significantly increased grazing efficiency during both seasons compared to Voisin restricted grazing, and had a much better impact upon grazing consumption as well. Neither yield indexes nor rest time were affected; they changed according to season with a marked depletion during dry season. Annual yield average was 11,7 t dry matter ha-1, out of which only a 23% was obtained during dry season. A higher graz- ing consumption index in  portion grazing showed a 24 UGM ha-1 increase in load capacity due to rotation during rainy season compared to Voisin restricted grazing (242 vs. 218). Results clearly showed a marked effect of season and grazing consumption upon  portion grazing.Se evaluó durante 4 años el efecto de los métodos de Pastoreo Racional Voisin (PRV) y Pastoreo Porcionado en los indicadores que determinan la capacidad de carga del pasto Brachiaria humidicola cv. CIAT 679 sin riego y fertilización en un suelo Vertisol del valle del Cauto. Se utilizaron 40 vacas 5/8 Holstein-3/8 Cebú en un diseño completamente aleatorio. El pastoreo se condujo “en línea”, con cuartones de tamaño fijo en el PRV y con franjas en el Porcionado, en el que se le asignó al rebaño una porción diaria de la franja de pastoreo según disponibilidad del pasto, para incrementar su aprovechamiento. El manejo de la oferta en el Pastoreo Porcionado incrementó significativamente la intensidad de pastoreo (IP) en ambas épocas del año con respecto al PRV y ejerció un efecto favorable en el aprovechamiento del pasto (AP) al encontrarse similar tendencia. Este hecho no afectó los indi- cadores de rendimiento y tiempo de reposo, que variaron con la época del año con una marcada depresión en la seca. El promedio de rendimiento anual fue 11,7 t MS ha-1 del cual solo el 23 % se obtuvo en seca. El mayor AP en el Pastoreo Porcionado incre- mentó en 24 UGM ha-1 la capacidad de carga por rotación en la lluvia con respecto al PRV (242 vs. 218). Los resultados demuestran el efecto marcado de la época del año y del aumento del AP en el Pastoreo Porcionado durante la época de lluvia

Combined therapy in diabetic macular edema

Purpose: To determine the effectiveness of three different combinations for the ‘‘loading phase’’ in the treatment of diabetic macular edema (DME), using bevacizumab (BVZ), triamcinolone (TCL) and subthreshold macular photocoagulation (SMPC). Methods: Experimental, longitudinal, prospective, comparative and blind. Patients were randomly assigned to three treatment branches: Group 1: BVZ + SMPC (12 eyes), Group 2: SMPC + BVZ + TCL (7 eyes), Group 3: BVZ + TCL (11 eyes). Treatment with BVZ and TCL was given every 4 weeks for 3 months, SMPC was applied once at the beginning of treatment. Initial and final measurements of best corrected visual acuity (BCVA), central macular thickness (CMT) and intraocular pressure (IOP) were tested. Results: The improvement in BCVA and the reduction in CMT was statistically superior in group of BVZ + SMPCwhen compared to the other groups. There were no differences in IOP. Conclusions: Combined therapies in the ‘‘loading phase’’are a good option when treating DME. Although the group with BVZ + SMPC obtained the best results, further studies with longer followup and a higher number of participants to establish this combined therapy as the first treatment option are required

A comparison of the taphonomic attributes of quarries VM3 and VM4 of the Early Pleistocene site of Venta Micena (Baza Basin, SE Spain)

The site of Venta Micena (Guadix-Baza Depression, SE Spain), a rich Fossil-Lagerstätten of late Early Pleistocene age (1.6-1.5 Ma), preserves a diverse assemblage of large mammals. Up to date, >24,000 skeletal remains have been unearthed from the surface excavated (~400 m2) in the two main quarries of the site, VM3 and VM4, which represents a density of fossils of >60/m2. Although this density is not homogeneously recorded across the 80-120 cm thick VM stratum, which outcrops over ~2.5 km, it suggests that tens of millions of fossils were preserved in the micritic limestones of this lithological unit. VM3 has been interpreted as a den of the giant hyena Pachycrocuta brevirostris in the plain that surrounded the Baza paleolake. Taphonomic analyses showed that the hyenas: (i) scavenged the prey hunted by the hypercarnivores, sabertoothed felids and wild dogs; (ii) transported the remains to their communal den as whole carcasses or selected anatomical parts; and (iii) fractured the skeletal parts according to their marrow contents and mineral density, which resulted in well-defined consumption sequences. In the case of VM4, an excavation quarry ~350 m distant from VM3, preliminary taphonomic analyses of the assemblage showed several differences, including: (i) a higher frequency of elements in anatomical connection than in VM3; (ii) a lower proportion of bones tooth-marked by carnivores (5.5%) compared with their frequency in VM3 (29.4%); (iii) a lower proportion of remains with salivary and gastric alterations (0.06% in both cases) than in VM3 (0.34% and 0.15%, respectively); and (iv) a less advanced degree of weathering (90.8% of bones show weathering stage 0 in VM4 compared to 75.9% in VM3).ICAZ Taphonomy Working Group, CSIC, MNCN Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Renal Function Impact in the Prognostic Value of Galectin-3 in Acute Heart Failure

[Abstract] Introduction: Galectin-3 (Gal-3) is an inflammatory marker associated with the development and progression of heart failure (HF). A close relationship between Gal-3 levels and renal function has been observed, but data on their interaction in patients with acute HF (AHF) are scarce. We aim to assess the prognostic relationship between renal function and Gal-3 during an AHF episode. Materials and methods: This is an observational, prospective, multicenter registry of patients hospitalized for AHF. Patients were divided into two groups according to estimated glomerular filtration rate (eGFR): preserved renal function (eGFR ≥ 60 mL/min/1.73 m2) and renal dysfunction (eGFR <60 mL/min/1.73 m2). Cox regression analysis was performed to evaluate the association between Gal-3 and 12-month mortality. Results: We included 1,201 patients in whom Gal-3 values were assessed at admission. The median value of Gal-3 in our population was 23.2 ng/mL (17.3-32.1). Gal-3 showed a negative correlation with eGFR (rho = -0.51; p < 0.001). Gal-3 concentrations were associated with higher mortality risk in the multivariate analysis after adjusting for eGFR and other prognostic variables [HR = 1.010 (95%-CI: 1.001-1.018); p = 0.038]. However, the prognostic value of Gal-3 was restricted to patients with renal dysfunction [HR = 1.010 (95%-CI: 1.001-1.019), p = 0.033] with optimal cutoff point of 31.5 ng/mL, with no prognostic value in the group with preserved renal function [HR = 0.990 (95%-CI: 0.964-1.017); p = 0.472]. Conclusions: Gal-3 is a marker of high mortality in patients with acute HF and renal dysfunction. Renal function influences the prognostic value of Gal-3 levels, which should be adjusted by eGFR for a correct interpretation.Grant No. RD06-0003-0000 Grant No. RD12/0042/000

Déjà vu: on the use of meat resources by sabretooth cats, hominins, and hyaenas in the Early Pleistocene site of Fuente Nueva 3 (Guadix‑Baza Depression, SE Spain)

The late Early Pleistocene archaeological site of Fuente Nueva 3 (Orce, Guadix-Baza Depression, SE Spain), dated to ~1.4 Ma, provides evidence on the subsistence strategies of the first hominin population that dispersed in Western Europe. The site preserves Oldowan tool assemblages associated with abundant remains of large mammals. A small proportion of these remains show cut marks and percussion marks resulting from defleshing and bone fracturing, and a small proportion of bones also show tooth marks. Previous taphonomic studies of FN3 suggested that the hominins had secondary access to the prey leftovers abandoned by sabretooth cats and other primary predators. However, a recent analysis by Yravedra et al. (2021) of the frequency of anthropogenic marks and tooth marks has concluded that the hominins had primary access to the carcasses of a wide variety of ungulate prey, even though the frequency of evisceration marks is strikingly low. In this rebuttal, we analyse the patterns of bone preservation in FN3, which show that the exploitation of bone marrow by the hominins after hammerstone breakage was a usual activity at the site. Our study also reviews the evidence available on the lesser abilities of sabretooth cats for carcass processing compared to pantherine felids. This reinforces the hypothesis that primary predators provided the hominins the opportunity to scavenge sizeable chunks of meat and bone marrow of their prey carcasses before the arrival of hyaenas. Finally, we also provide new inferences on resource availability and competition intensity among the members of the carnivore guild in FN3, which reinforce our interpretation that a secondary access by the Oldowan hominins to the prey leftovers of sabretooth cats was an optimal foraging strategy in the Guadix-Baza Depression.Funding for open access publishing: Universidad Málaga/CBUA This work has been granted by projects CGL-2016-78577-P, CGL-2016-80975-P, and PID2019-111185GB-I00 of the Spanish Ministry of Science, Innovation and University, “Junta de Andalucía” (FEDER) project UMA18-FEDERJA-188, “Generalitat de Catalunya” grant GENCAT 2017SGR 859, and by Research Group RNM-146 from “Junta de Andalucía.” Funding for open access charge: Universidad de Málaga / CBU