29 research outputs found
A Cross-Over in the Enstrophy Decay in Two-Dimensional Turbulence in a Finite Box
The numerical simulation of two-dimensional decaying turbulence in a large
but finite box presented in this paper uncovered two physically different
regimes of enstrophy decay. During the initial stage, the enstrophy, generated
by a random Gaussian initial condition, decays as t^{-gamma} with gamma
approximately 0.7-0.8. After that, the flow undergoes a transition to a gas or
fluid composed of distinct vortices. Simultaneously, the magnitude of the decay
exponent crosses over to gamma approximately 0.4. An exact relation for the
total number of vortices, N(t), in terms of the mean circulation of an
individual vortex is derived. A theory predicting that N(t) is proportional to
t^{-xi} and the magnitudes of exponents gamma=2/5 and xi=4/5 is presented and
the possibility of an additional very late-time cross-over to gamma=1/3 and
xi=2/3 is also discussed.Comment: 11 pages, 7 figure
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe
Status of the 25 T, 100 mm Bore HTS Solenoid for an Axion Dark Matter Search Experiment
This paper presents the design and test results of the pancake coils for the 25 T, 100 mm bore solenoid that Brookhaven National Laboratory (BNL) is building for the Insti-tute for Basic Science (IBS) in Korea for an Axion dark matter search. The design is based on second generation (2G) High Temperature Superconducting (HTS) tape with no-insulation winding. The major challenges in the high field, large aperture solenoid are the large stresses and the quench protection. Moreo-ver, the design should be robust for reliable operation in a user facility environment. The paper will also present the construction and test results of two ∼100 mm bore double pancake coils creat-ing a peak field of up to ∼17 T and similar hoop stresses as will be in the 25 T solenoid. The coils were subject to several severe tests, including the simulations of large defects and extended quench studies at ∼4 K. The most striking part of these studies was the demonstration of how fast (a few hundred milliseconds) these coils can turn from the superconducting state to the normal state (quench or thermal runaway). This removes the past concerns of protecting high field HTS coils because of the low quench propa-gation velocities. © 2019 IEEE
Recent Test Results of the Fast-Pulsed 4 T COS Dipole GSI 001
For the FAIR-project at GSI a model dipole was built at BNL with the nominal field of 4 T and a nominal ramp rate of 1 T/s. The magnet design was similar to the RHIC dipole with some changes for loss reduction and better cooling. The magnet was already successfully tested in a vertical cryostat with good training behaviour. Cryogenic losses were measured and first results of field harmonics were published. However, for a better understanding of the cooling process quench currents at several ramp rates were investigated. Detailed measurements of the field harmonics at different ramp rates and at several cycles were performed. To separate the effects of the coil and the iron yoke the magnet was disassembled and tested as collared coil only. Recent test results will be presented