15 research outputs found
Closure of a large lumbosacral myelomeningocele post operative defect with a human cadaveric split-thickness skin graft: a case report
- Author
- Publication venue
- 'Medip Academy'
- Publication date
- 25/11/2022
- Field of study
Spina bifida is the most common birth defect of the central nervous system that is compatible with life, and myelomeningocele represents its most frequent form. Congenital myelomeningocele (CMM) has a worldwide incidence of 0.5 to 0.8 per 1,000 live newborns. CMM is a complex condition resulting from incomplete closure of the neural tube, mainly in the lumbosacral region. The objective of the surgical repair of the CMM is the reconstruction of all the tissue layers of the defect, avoiding possible postoperative complications. The aim of this case review is to present a re-epithelialization closure in a patient with a large CMM defect in who primary hermetic closure was not possible because there was too much tension at the edges of the defect. Therefore, human cadaveric split-thickness skin grafts were placed over the dura mater and the aponeurotic layer, covering the entire defect and an adequate healing and completely closure of the defect were observed in eight weeks. The surgical management of large meningomyelocele defects represents a major challenge and no single protocol exists for its reconstruction. The repair of an MMC defect should be performed during the first 72 hours after birth. After neurosurgical closure of the neural tube and dura, the myelomeningocele defect requires good quality skin and subcutaneous tissue with minimal wound tension for stable coverage. Human cadaveric skin grafts are considered a useful technique for temporary wound coverage because they lead to a more natural healing environment, possess ideal properties, and provide a physiological barrier that reduces microbiological contamination, in addition, it acts as a bridge to adhere to and to seal wound beds
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre Windsor E.
- Akinwole Philips O.
- Alberti Marina
- Anderson Jill T.
- Anderson Joseph J.
- Ando Yoshino
- Andrew Nigel R.
- Angeoletto Fabio
- Anstett Daniel N.
- Anstett Julia
- Aoki-Gonçalves Felipe
- Arietta A. Z. Andis
- Arroyo Mary T. K.
- Austen Emily J.
- Baena-DĂaz Fernanda
- Barker Cory A.
- Baylis Howard A.
- Beliz Julia M.
- Benitez-Mora Alfonso
- Bickford David
- Biedebach Gabriela
- Blackburn Gwylim S.
- Boehm Mannfred M. A.
- Bonser Stephen P.
- Bonte Dries
- Bragger Jesse R.
- Branquinho Cristina
- Brans Kristien I.
- Bresciano Jorge C.
- Brom Peta D.
- Bucharova Anna
- Burt Briana
- Cahill James F.
- Campbell Katelyn D.
- Carlen Elizabeth J.
- Carmona Diego
- Castellanos Maria Clara
- Centenaro Giada
- Chalen Izan
- Chaves Jaime A.
- Chen Xiao-Yong
- Chilton Angela M.
- Chomiak Kristina M.
- ChĂĄvez-Pesqueira Mariana
- Cisneros-Heredia Diego F.
- Cisse Ibrahim K.
- Classen Aimée T.
- Cohan Beata
- Comerford Mattheau S.
- Corney Hannah
- Crawford Andrew J.
- Crawford Kerri M.
- Dahirel Maxime
- David Santiago
- De Haan Robert
- Deacon Nicholas J.
- Dean Clare
- del-Val Ek
- Deligiannis Eleftherios K.
- Denney Derek
- Dettlaff Margarete A.
- DiLeo Michelle F.
- Ding Yuan-Yuan
- Dominoni Davide M.
- DomĂnguez-LĂłpez MoisĂ©s E.
- Draud Savannah L.
- Dyson Karen
- Ellers Jacintha
- Espinosa Carlos I.
- Essi Liliana
- Falahati-Anbaran Mohsen
- FalcĂŁo JĂ©ssica C. F.
- Fargo Hayden T.
- Fellowes Mark D. E.
- Fitzpatrick Connor R.
- Fitzpatrick Raina M.
- Flaherty Leah E.
- Flood PĂĄdraic J.
- Flores MarĂa F.
- Fornoni Juan
- Foster Amy G.
- Fradinger Camila Cordoba
- Frost Christopher J.
- Fuentes Tracy L.
- Fulkerson Justin R.
- Gagnon Edeline
- Garbsch Frauke
- Garroway Colin J.
- Gerstein Aleeza C.
- Giasson Mischa M.
- Girdler E. Binney
- Gkelis Spyros
- Godsoe William
- Golemiec Anneke M.
- Golemiec Mireille
- GonzĂĄlez-Lagos CĂ©sar
- Gorton Amanda J.
- Gotanda Kiyoko M.
- Granath Gustaf
- Greiner Stephan
- Griffiths Joanna S.
- Grilo Filipa
- Gundel Pedro E.
- Hamilton Benjamin
- Hardin Joyce M.
- He Tianhua
- Heard Stephen B.
- Henriques André F.
- HernĂĄndez-Poveda Melissa
- Hetherington-Rauth Molly C.
- Hill Sarah J.
- Hochuli Dieter F.
- Hodgins Kathryn A.
- Hood Glen R.
- Hopkins Gareth R.
- Hovanes Katherine A.
- Howard Ava R.
- Hubbard Sierra C.
- Ibarra-Cerdeña Carlos N.
- Innes Simon G.
- Iñiguez-Armijos Carlos
- Jara-Arancio Paola
- Jarrett Benjamin J. M.
- Jeannot Manon
- Jiménez-Lobato Vania
- Johnson Mae
- Johnson Marc T. J.
- Johnson Oscar
- Johnson Philip P.
- Johnson Reagan
- Josephson Matthew P.
- Jung Meen Chel
- Just Michael G.
- Kahilainen Aapo
- Kailing Otto S.
- Kariñho-Betancourt Eunice
- Karousou Regina
- Kirn Lauren A.
- Kirschbaum Anna
- Koch Sophie
- Laine Anna-Liisa
- LaMontagne Jalene M.
- Lampei Christian
- Lara Carlos
- Larson Erica L.
- Le Jennifer H.
- Leandro Deleon S.
- Lee Christopher
- Lei Yunting
- Lequerica Tamara Manuel E.
- Levesque Danica C.
- LeĂłn Carolina A.
- Liao Wan-Jin
- Ljubotina Megan
- Locke Hannah
- Lockett Martin T.
- Longo Tiffany C.
- Lundholm Jeremy T.
- LĂĄzaro-Lobo AdriĂĄn
- MacGillavry Thomas
- Mackin Christopher R.
- Mahmoud Alex R.
- Manju Isaac A.
- Mariën Janine
- MartĂnez D. Nayeli
- MartĂnez-BartolomĂ© Marina
- Meineke Emily K.
- Mendoza-Arroyo Wendy
- Merritt Lila Elizabeth L.
- Merritt Thomas J. S.
- Migiani Giuditta
- Miles Lindsay S.
- Minor Emily S.
- Mitchell Nora
- Mohammadi Bazargani Mitra
- Moles Angela T.
- Monk Julia D.
- Moore Christopher M.
- Morales-Morales Paula A.
- Moyers Brook T.
- Munim Samreen
- Munshi-South Jason
- Murphy Shannon M.
- MurĂșa Maureen M.
- Muñoz-Rojas Miriam
- Neila Melisa
- Ness Rob W.
- Nikolaidis Ourania
- NjunjiÄ Iva
- Nosko Peter
- NĂșñez-FarfĂĄn Juan
- Ohgushi Takayuki
- Olsen Kenneth M.
- Opedal Ăystein H.
- Ornelas Cristina
- Parachnowitsch Amy L.
- Paratore Aaron S.
- Parody-Merino Angela M.
- Paule Juraj
- Paulo OctĂĄvio S.
- Pena JoĂŁo Carlos
- Peres-Neto Pedro R.
- Pfeiffer Vera W.
- Pinho Pedro
- Piot Anthony
- Porth Ilga M.
- Poulos Nicholas
- Prashad Cindy
- Puentes Adriana
- Qu Jiao
- Quintero-Vallejo Estela
- Raciti Steve M.
- Raeymaekers Joost A. M.
- Raveala Krista M.
- Rennison Diana J.
- Ribeiro Milton C.
- Richardson Jonathan L.
- Rivas-Torres Gonzalo
- Rivera Benjamin J.
- Roddy Adam B.
- Rodriguez-Muñoz Erika
- RomĂĄn JosĂ© RaĂșl
- Rossi Laura S.
- Rowntree Jennifer K.
- Ryan Travis J.
- Salinas Santiago
- Sanders Nathan J.
- Santangelo James S.
- Santiago-Rosario Luis Y.
- Savage Amy M.
- Scheepens J.F.
- Schilthuizen Menno
- Schneider Adam C.
- Scholier Tiffany
- Scott Jared L.
- Shaheed Summer A.
- Shefferson Richard P.
- Shepard Caralee A.
- Shykoff Jacqui A.
- Silveira Georgianna
- Smith Alexis D.
- Solis-Gabriel Lizet
- Soro Antonella
- Spellman Katie V.
- Starke-Ottich Indra
- Stephan Jörg G.
- Stephens Jessica D.
- Szulc Justyna
- Szulkin Marta
- Tack Ayco J. M.
- Tamburrino Ătalo
- Tate Tayler D.
- Tergemina Emmanuel
- Theodorou Panagiotis
- Thompson Ken A.
- Threlfall Caragh G.
- Tinghitella Robin M.
- Toledo-Chelala Lilibeth
- Tong Alex T.
- Tong Xin
- Uroy LĂ©a
- Utsumi Shunsuke
- Vandegehuchte Martijn L.
- VanWallendael Acer
- Vidal Paula M.
- Wadgymar Susana M.
- Wang Ai-Ying
- Wang Nian
- Warbrick Montana L.
- Whitney Kaitlin Stack
- Whitney Kenneth D.
- Wiesmeier Miriam
- Wiles J. Tristian
- Wu Jianqiang
- Xirocostas Zoe A.
- Yan Zhaogui
- Yao Jiahe
- Yoder Jeremy B.
- Yoshida Owen
- Zhang Jingxiong
- Zhao Zhigang
- Ziter Carly D.
- Zuellig Matthew P.
- Zufall Rebecca A.
- Zurita Juan E.
- Zytynska Sharon E.
- Ălvarez Jackie
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2022
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study
- Author
- A A Essam
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled AbdRabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewer
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd El-Sameea
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Alkhatib
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Said Badr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat PektaĆ
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de LeĂłn
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alissa GĂŒbeli
- Alistair Rocke
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
- Aly Abd-Elrazek
- Aly Sanad
- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amgad Al Meligy
- Amina Abdelhamid
- Aminah Hanum Haji Abdul Majid
- Aminu Mohammad
- Amir Ait Kaci
- Amira Elsawy
- Amira Hassan Bekhet
- Amira Reda
- Amjad Abu Qumbos
- Amjad Elmashala
- Ammar Gado
- Amna Mamdouh Mohamed
- Amna Mohamed
- Amr Ahmed Saleh
- Amr Hassaan
- Amr Hossameldin
- Amreen Faruq
- Amro Aglan
- Ana Lucia Contreras-Vergara
- Ana Maria Sandoval Barrantes
- Anahita Mansuri
- Anan Rady Abdelazeam
- Anass Majbar
- Anastasios Stefanopoulos
- Anders Thorell
- Andre L Mihaljevic
- Andre Navarro
- Andrea Armellini
- Andrea Belli
- Andrea Bondurri
- Andrea Craus-Miguel
- Andrea Natili
- Andrea Ruzzenente
- Andrea Simioni
- Andreass Haloho
- Andrejus Subocius
- Andrew Kirby
- Andrey Litvin
- Andrius Burmistrovas
- Angel David PĂ©rez Rojas
- Angela Dell
- Angela Mazzella
- Angelica Genoveva Vergara Mejia
- Angeline Charles
- Angelo Antoniozzi
- Angelo Benevento
- Angelos Tselos
- Anil Kaul
- Anil Semiz
- Ankur Bhatnagar
- Anmar Homeida
- Anna Jeffery
- Anna Lasek
- Anna Maffioli
- Anna Rinaldi
- Anna Verbeek
- Annalisa Lo Conte
- Annamaria Bigaran
- Annisa Dewi Fitriana Mukin
- Antanas Gulbinas
- Antanas Zadoroznas
- Anthonius Santoso Rulie
- Anthony Ajiboye
- Anthony Avoka
- Anthony Chuk-Him Lai
- Anthony Davor
- Anthony Sander
- Antoinette Bediako-Bowan
- Antonella La Brocca
- Antonio Nocito
- Antonio Picardo
- Antonio Ramos-De la Medina
- Antonio Taddei
- Anwar Atiyeh
- Anyomih Theophilus Teddy Kojo
- April Camilla Roslani
- Aram Abdelhaq
- Arazzelly Del Pilar Paucar
- Arcangelo Picciariello
- Arestis Sokratous
- Arezo Kanani
- Ari LeppÀniemi
- Ariadne L'Heveder
- Arianna Birindelli
- Arij Ibrahim
- Arjun Paramasivan
- Arlindawati Suyadi
- Armando José Romån Velåsquez
- Arnav Agarwal
- Aroub Alkaaki
- Arturas Vaicius
- Arvin Khamajeet
- Arvo Reinsoo
- Arwa Abouzaid
- Arwa Elfarargy
- Arwa Ibrahim
- Arwa Mohamed
- Asad Choudhry
- Asaf Kedar
- Asdaq Ahmed
- Aseel Alnusairat
- Aseel Hamarshi
- Aseel Musleh
- Ashish Gupta
- Ashish Minocha
- Ashraf Maghrabi
- Ashrafun Nessa
- Ashrarur Rahman Mitul
- Ashwath Bandi
- Asmaa Rezq
- Asmaa Salah
- Asnel Dorismé
- Aspasia Papailia
- Astrid Leusink
- Ataa Ahmed
- Athanasia Bamicha
- Athar Abbas
- Athirah Zulkifli
- Athula Tennakoon
- Attia Attia
- Audrey Clarissa
- Audrius Dulskas
- Audrius Parseliunas
- Augusto Zani
- Aurel Mironescu
- Aurel Sandu Mironescu
- Aurelien Scalabre
- Aurora Mariani
- Aurore Haffreingue
- Aurore Thollot
- Awais Raza
- Aya Abdelfatah Ibraheem
- Aya Adel Elsharkawy
- Aya El-Sawy
- Aya Firwana
- Aya Hammad
- Aya Mohamed Fathy
- Aya Reda
- Aya Yehia Ata
- Ayah Hamdan
- Ayat Hassaan
- Ayman And Taher
- Ayman Salman
- Ayman Shwky
- Azher Herebat
- Babajide Adenekan
- Babatunde Odeyemi
- Badr Eldin Adel
- Badreldin Adel Tawfik
- Bahadir Emre Baki
- Bahar Busra Ozkan
- Bakeer Mohamed
- Basant Kumar
- Bashir Bello
- Basma Mahmoud
- Basmah Alhassan
- Bassant Mowafy
- Beatrice Brunoni
- Behrad Barmayehvar
- Belen Sanchez
- BenogreĂźt Parmentier
- Berk Baris Ozmen
- Berna Buse Kobal
- Bernard Limoges
- Bernhard Wolf
- Bertrand Dousset
- Besmir Grizhja
- Bettina Lieske
- Betty Maillot
- Bogdan Diaconescu
- Britta Dedekind
- Bruno Noukpozounkou
- Busra Murutoglu
- BĂĄrbara MĂĄlaga
- Calogero Iacono
- Calvin Eng
- Cameron Fairfield
- Camila Sanchez Samaniego
- Camilla Cona
- Can Adiyaman
- Carla Soldevila-Verdeguer
- Carlo Corbellini
- Carlos Nsengiyumva
- Carlos Paz Galvez
- Carly Bisset
- Carmen Capito
- Carmen FernĂĄndez
- Carmen GarcĂa Bernardo
- Carmina Diaz Zorrilla
- Carolina Guzmån Dueñas
- Caroluce K Musyoka
- Catherine A Shaw
- Catrin Jones
- Catrin Morgan
- Cecile Muller
- Cecilia Costa
- Cedar Andress
- Celeste Caliman
- Celeste Del Basso
- Cesar Miranda
- Cesar Razuri
- Cezar Ciubotaru
- Chali Chibuye
- Challine Alexandre
- Charlene Tan
- Charles Dally
- Chaymae Benyaiche
- Cheewei Gan
- Chelise Currow
- Chelsea Deane
- Chetan Khatri
- Chi Chung Foo
- Chi Ying Jacquelyn Fok
- Chia Kong
- Chimwemwe Kwatiwani
- Chingwan Yip
- Chloe Roy
- Choon Seng Chong
- Chouikh Taieb
- Choy Ling Tan
- Chris Bode
- Christel Leanne Almanon
- Christian Lari Coompson
- Christina Panteli
- Christine Mizzi
- Christoforos Ferousis
- Christopher Owen
- Christopher Smith
- Christos Agalianos
- Christos Anthoulakis
- Christos Barkolias
- Chu-Ann Chai
- Chui Yee Wong
- Cicilia Viany Evajelista
- Ciskje Zarb
- Citra Dewi Mohd Ali
- Claire Sharpin
- Clare Skerritt
- Claudia Reali
- Claudio Arcudi
- Claudio Gabriel Fermani
- Clement Onuoha
- Colombani Jean-Francois
- Cornelius Mukuzunga
- Corrado Bottini
- Cristina Fernandes
- Cristina Pineño-Flores
- Crystal Yern Nee Chow
- CĂ©line Grosos
- D C Grobler
- Damir Ljuhar
- Dana Jaradat
- Daniel Cox
- Daniel Frey
- Daniel Hamill
- Daniela Magri
- Daniele Angelieri
- Daniele Gui
- Danilo Herrera Cruz
- Danjuma Sale
- Dansou Gaspard Gbessi
- Dario Andreotti
- David Ambrona-Zafra
- David Bunting
- David Evans
- David Ewart Henshall
- David Merlini
- David Monterroso Cohen
- Davide De Boni
- Davide Rossi
- Dayang Nita Abdul Aziz
- Dayson Kumwenda
- Debkumar Chowdhury
- Deborah Chiesa
- Deborah Saraste
- Deimante Mikuckyte
- Deividas Dragatas
- Demi Gray
- Deniz Mutlu
- Dennis Oswald
- Dharminder Dhillon
- Diaaaldin Zahran
- Diana Sanchez
- Dickson Bandoh
- Diego Antezana
- Diego Coletta
- Diego Romani
- Diego Sasia
- Dieudonne Duhoranenayo
- Dima Nassif
- Dimitri Aristotle Raptis
- Dimitrios Balalis
- Dimitrios K Manatakis
- Dimitrios Korkolis
- Dimitrios Kyziridis
- Dimitrios Lytras
- Dimitrios Papageorgiou
- Dimitrios Sfougaris
- Dina Al-Marakby
- Dina Faizatur Rahmah
- Dina Fouad
- Dina Gamal
- Dina Tarek
- Dion Morton
- Djifid Morel Seto
- Dmitri Nepogodiev
- Dmitri Raptis
- Doaa Gamil
- Doaa Hasan
- Doaa Hasanain
- Doaa Maher Abdelrouf
- Domenica Pata
- Dominic Townsend
- Donal B O'Connor
- Donatas Danys
- Donatas Venskutonis
- Dorota Radkowiak
- Dorothy Kufeji
- DovilÚ Majauskyté
- Durvesh Lacthman Jethwani
- Dush Iyer
- Dushyant Iyer
- Dzianis Khokha
- Dzmitry Paulouski
- Ebenezer Takyi Atkins
- Echaieb Anis
- Edgar Domini
- Edvard Grisin
- Edvinas Dainius
- Eimear Monaghan
- Eirik Kjus Aahlin
- Ekin Arslan
- Ekow Mensah
- Elaine Borg
- Elena Goldin
- Elena Muzio
- Elena Vendramin
- Elena Zdanyte Sruogiene
- Eleonora Ciccioli
- Eliana Kalakouti
- Elio Jovine
- Elisa Contreras
- Elisa Francone
- Elisabeth Hall
- Elisabeth Jensen
- Elissa Rifhan Mohd Basir
- Elizabeth Evans
- Elke Reunis
- Ella Teasdale
- Elliot Akoto
- Elodie Haraux
- Eloy Espin-Basany
- Elsa Robert
- Elsayed Ali
- Emad Abdallah
- Emad Al-Dakka
- Eman Abd Al Raouf
- Eman Abdelmageed
- Eman Abuqwaider
- Eman Elwy
- Eman Emara
- Eman Hashad
- Eman Ibrahim
- Eman Magdy
- Eman Magdy Hegazy
- Eman Mahmoud Abdulhakeem
- Eman Mohamed Ibrahim
- Eman Mohamed Morshedy
- Eman Rashad
- Eman Yahya Mansor
- Emeka Nwabuoku
- Emilia de Luca
- Emilio Dijan
- Emin Kose
- Emmanuel Acquah
- Emmanuel Akatibo
- Emmanuel Barrios
- Enas Alaloul
- Enisburak GĂŒl
- Enkhbat Dashnyam
- Enoch Dagoe
- Enoch Tackie
- Enrique Esteban
- Eric Ackom
- Eric Etchill
- Eric Kofi Appiah
- Erick Samuel Florez Farfan
- Erik Hervieux
- Erik Schadde
- Erika Vicario
- Erikas Laugzemys
- Ernest Yemalin Stephane Ahounou
- Eslam Ezzat
- Esraa Abd Elkhalek
- Esraa Abdalmageed Kasem
- Esraa Alm Eldeen
- Esraa El Halawany
- Esraa El-Gizawy
- Esraa El-Taher
- Esraa Gamal
- Esraa Samir Elbanby
- Esraay Zakaria
- Esther Ferrero
- Esther Hg Park
- Ethar Hany
- Etienne Courboin
- Eu Xian Lee
- Eugenio Morandi
- Eunice Zuling Ter
- Evangelos Voulgaris
- Evelina Slapelyte
- Ewen Griffiths
- Ewen M Harrison
- Eyad Khalifah
- Fabrizio Aquilino
- Fahd Abdel Sabour
- Faisal Idris
- Faith Qi Hui Leong
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- Sarah Rayne
- Sarah Sahel
- Saraibrahim Ahmed
- Saulius Bradulskis
- Saulius Mikalauskas
- Savino Occhionorelli
- Savva Pronin
- Sawsan Adel Awad
- Sayeda Nazmum Nahar
- Sayeeda Aktar Tori
- Scott D'Amours
- Sean Mizzi
- Sebastian King
- Sebastian Shu
- Sebastian Sierra
- Sebastien Gaujoux
- Sebestian Shu
- Seehui Chiu
- Sefa Bayram
- Selim Bodur
- Serena Manfreda
- Serge Kapenda Tshisola
- Sergio Ribaldi
- Servet Rustu Karahan
- Servio Tulio Torres Rodriguez
- Shadid Al Amin
- Shadid Alamin
- Shady Elhadry
- Shady Mahmoud
- Shahadatul Shaharuddin
- Shahinaz Alaa El-Din
- Shahinaz Alaael-Dein
- Shahrukh Mirza
- Shalon Guevara Torres
- Shamsudeen Aliyu
- Sharad Karandikar
- Shareef Mahdi
- Sharon Koh
- Shaun Oram
- Shayanthan Nanthakumaran
- Shaza Rabie Mohamed
- Sherif Tariq
- Shimaa Gamal
- Shimaa Said Elkholy
- Shireen Gaafar
- Shiva Dindyal
- Shivanchan Rajmohan
- Shivun Khosla
- Shpetim Ymeri
- Shu Ning Kong
- Shuang Yi Teo
- Shujing Jane Lim
- Shyang Yee Lim
- Sibongile Ruth Ndlovu
- Silje Holte
- Silke Mahanty
- Silvia BasilicĂČ
- Silvia Boni
- Silvia De Franciscis
- Simon Cole
- Simon Paterson-Brown
- Simon Stock
- Simona Kasputyte
- Simone Conci
- Simone Sandler
- Simone Targa
- Sinem Yolcu
- Sir Young Yam
- Siti Mohd Desa Asilah
- Siti Nur Alia Kamarulzamil
- Sivesh K Kamarajah
- Sobhana Iftekhar Tani
- Soha Abushamleh
- Sohaila Elmihy
- Sondos Turkustani
- Sophian Hmila
- Spb Thalgaspitiya
- Stavros Parasyris
- Stefan Zammit
- Stefano Berti
- Stefano Giuliani
- Stefano Mm Basso
- Sten Saar
- Stephanie Hiu-Wai Kwok
- Stephanie Van Straten
- Stephen Kache
- Stephen Knight
- Stephen O'Neill
- Stephen Tabiri
- Steponas Petrikenas
- Stuart J Fergusson
- Styliani Parpoudi
- Stylianos Germanos
- Suhhuey Yap
- Sukrit Suresh
- Sule Burger
- Suleiman Baba
- Sunil Kumar
- Suraj Kadiwar
- Suraya Bahar
- Susan Aviles
- Susan McGarvie
- Susan Wndy Mathew
- Suzanne Kershaw
- Svetlana Doris Brincat
- Swapnil Roy
- Syed Abdul Wahhab Eusoffee Wan Ali
- Syed Asaat Ul Razi
- Sylvia Kamya
- Sylvie Mochet
- Syrine Rekhis
- T Ariani Widiastini
- Taha Yusufali
- Taher Al-Taher
- Taiwo Lawal
- Talar Vartanoglu
- Tamara Diaz Vico
- Tanzeela Gala
- Tara Grima
- Tarek Ezzat
- Tariq Alhammali
- Tasneem Idress
- Tasnia Hamid Kanta
- Tatsiana Shachykava
- Tebian Hassanein Ahmed Ali
- Tewodros Worku
- Thamer Nouh
- Thandinkosi Madiba
- Tharindra Dissanayake
- Thays Brunelli Pugliesi
- Thea Dimech
- Thelma Tembo
- Theodore Pezas
- Theodosios Theodosopoulos
- Therese Duane
- Thierry Alihonou
- Thomas Feidantsis
- Thomas Kidd
- Thomas M Drake
- Thomas Mann
- Thomas Olagboyega Olajide
- Thomas Pinkney
- Thomas Prudhomme
- Thomas Tetens Moe
- Tien Seng Bryan Lee
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Abbott
- Tom Arthur
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poskus
- Tomas PoĆĄkus
- Tomas Urbonas
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Toqa Khafagy
- Torhild Veen
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tunde Sholadoye
- Turgut Bora Cengiz
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uttaran Datta
- Vahit Mutlu
- Valdemaras Jotautas
- Valeria Andriola
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Vedatcan IĆler
- Veeranna Shatkar
- Venerand Barendegere
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Nwinee
- Vijaid Upadhyaya
- Viktorija Nevieraite
- Ville Sallinen
- Vincas Jonas Banaitis
- Virginia Jiménez Carneros
- Virginia Ramos PĂ©rez
- Viviana Sollazzo
- Vladimir Khokha
- Volkan Ozben
- Vu Thanh Hien Le
- Vytautas GaiĆŸauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos BermĂșdez
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas UrnieĆŸius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ămer Faruk Toto
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.Peer reviewe
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre Windsor E.
- Akinwole Philips O.
- Alberti Marina
- Anderson Jill T.
- Anderson Joseph J.
- Ando Yoshino
- Andrew Nigel R.
- Angeoletto Fabio
- Anstett Daniel N.
- Anstett Julia
- Aoki-Gonçalves Felipe
- Arietta A. Z.Andis
- Arroyo Mary T.K.
- Austen Emily J.
- Baena-DĂaz Fernanda
- Barker Cory A.
- Baylis Howard A.
- Beliz Julia M.
- Benitez-Mora Alfonso
- Bickford David
- Biedebach Gabriela
- Blackburn Gwylim S.
- Boehm Mannfred M.A.
- Bonser Stephen P.
- Bonte Dries
- Bragger Jesse R.
- Branquinho Cristina
- Brans Kristien I.
- Bresciano Jorge C.
- Brom Peta D.
- Bucharova Anna
- Burt Briana
- Cahill James F.
- Campbell Katelyn D.
- Carlen Elizabeth J.
- Carmona Diego
- Castellanos Maria Clara
- Centenaro Giada
- Chalen Izan
- Chaves Jaime A.
- Chen Xiao Yong
- Chilton Angela M.
- Chomiak Kristina M.
- ChĂĄvez-Pesqueira Mariana
- Cisneros-Heredia Diego F.
- Cisse Ibrahim K.
- Classen Aimée T.
- Cohan Beata
- Comerford Mattheau S.
- Corney Hannah
- Crawford Andrew J.
- Crawford Kerri M.
- Dahirel Maxime
- David Santiago
- De Haan Robert
- Deacon Nicholas J.
- Dean Clare
- Del-Val Ek
- Deligiannis Eleftherios K.
- Denney Derek
- Dettlaff Margarete A.
- DiLeo Michelle F.
- Ding Yuan Yuan
- Dominoni Davide M.
- DomĂnguez-LĂłpez MoisĂ©s E.
- Draud Savannah L.
- Dyson Karen
- Ellers Jacintha
- Espinosa Carlos I.
- Essi Liliana
- Falahati-Anbaran Mohsen
- FalcĂŁo JĂ©ssica C.F.
- Fargo Hayden T.
- Fellowes Mark D.E.
- Fitzpatrick Connor R.
- Fitzpatrick Raina M.
- Flaherty Leah E.
- Flood PĂĄdraic J.
- Flores MarĂa F.
- Fornoni Juan
- Foster Amy G.
- Fradinger Camila Cordoba
- Frost Christopher J.
- Fuentes Tracy L.
- Fulkerson Justin R.
- Gagnon Edeline
- Garbsch Frauke
- Garroway Colin J.
- Gerstein Aleeza C.
- Giasson Mischa M.
- Girdler E. Binney
- Gkelis Spyros
- Godsoe William
- Golemiec Anneke M.
- Golemiec Mireille
- GonzĂĄlez-Lagos CĂ©sar
- Gorton Amanda J.
- Gotanda Kiyoko M.
- Granath Gustaf
- Greiner Stephan
- Griffiths Joanna S.
- Grilo Filipa
- Gundel Pedro E.
- Hamilton Benjamin
- Hardin Joyce M.
- He Tianhua
- Heard Stephen B.
- Henriques André F.
- HernĂĄndez-Poveda Melissa
- Hetherington-Rauth Molly C.
- Hill Sarah J.
- Hochuli Dieter F.
- Hodgins Kathryn A.
- Hood Glen R.
- Hopkins Gareth R.
- Hovanes Katherine A.
- Howard Ava R.
- Hubbard Sierra C.
- Ibarra-Cerdeña Carlos N.
- Innes Simon G.
- Iñiguez-Armijos Carlos
- Jara-Arancio Paola
- Jarrett Benjamin J.M.
- Jeannot Manon
- Jiménez-Lobato Vania
- Johnson Mae
- Johnson Marc T.J.
- Johnson Oscar
- Johnson Philip P.
- Johnson Reagan
- Josephson Matthew P.
- Jung Meen Chel
- Just Michael G.
- Kahilainen Aapo
- Kailing Otto S.
- Kariñho-Betancourt Eunice
- Karousou Regina
- Kirn Lauren A.
- Kirschbaum Anna
- Koch Sophie
- Laine Anna Liisa
- LaMontagne Jalene M.
- Lampei Christian
- Lara Carlos
- Larson Erica L.
- Le Jennifer H.
- Leandro Deleon S.
- Lee Christopher
- Lei Yunting
- Lequerica Tamara Manuel E.
- Levesque Danica C.
- LeĂłn Carolina A.
- Liao Wan Jin
- Ljubotina Megan
- Locke Hannah
- Lockett Martin T.
- Longo Tiffany C.
- Lundholm Jeremy T.
- LĂĄzaro-Lobo AdriĂĄn
- MacGillavry Thomas
- Mackin Christopher R.
- Mahmoud Alex R.
- Manju Isaac A.
- Mariën Janine
- MartĂnez D. Nayeli
- MartĂnez-BartolomĂ© Marina
- Meineke Emily K.
- Mendoza-Arroyo Wendy
- Merritt Lila Elizabeth L.
- Merritt Thomas J.S.
- Migiani Giuditta
- Miles Lindsay S.
- Minor Emily S.
- Mitchell Nora
- Mohammadi Bazargani Mitra
- Moles Angela T.
- Monk Julia D.
- Moore Christopher M.
- Morales-Morales Paula A.
- Moyers Brook T.
- Munim Samreen
- Munshi-South Jason
- Murphy Shannon M.
- MurĂșa Maureen M.
- Muñoz-Rojas Miriam
- Neila Melisa
- Ness Rob W.
- Nikolaidis Ourania
- NjunjiÄ Iva
- Nosko Peter
- NĂșñez-FarfĂĄn Juan
- Ohgushi Takayuki
- Olsen Kenneth M.
- Opedal Ăystein H.
- Ornelas Cristina
- Parachnowitsch Amy L.
- Paratore Aaron S.
- Parody-Merino Angela M.
- Paule Juraj
- Paulo OctĂĄvio S.
- Pena JoĂŁo Carlos
- Peres-Neto Pedro R.
- Pfeiffer Vera W.
- Pinho Pedro
- Piot Anthony
- Porth Ilga M.
- Poulos Nicholas
- Prashad Cindy
- Puentes Adriana
- Qu Jiao
- Quintero-Vallejo Estela
- Raciti Steve M.
- Raeymaekers Joost A.M.
- Raveala Krista M.
- Rennison Diana J.
- Ribeiro Milton C.
- Richardson Jonathan L.
- Rivas-Torres Gonzalo
- Rivera Benjamin J.
- Roddy Adam B.
- Rodriguez-Muñoz Erika
- RomĂĄn JosĂ© RaĂșl
- Rossi Laura S.
- Rowntree Jennifer K.
- Ryan Travis J.
- Salinas Santiago
- Sanders Nathan J.
- Santangelo James S.
- Santiago-Rosario Luis Y.
- Savage Amy M.
- Scheepens J. F.
- Schilthuizen Menno
- Schneider Adam C.
- Scholier Tiffany
- Scott Jared L.
- Shaheed Summer A.
- Shefferson Richard P.
- Shepard Caralee A.
- Shykoff Jacqui A.
- Silveira Georgianna
- Smith Alexis D.
- Solis-Gabriel Lizet
- Soro Antonella
- Spellman Katie V.
- Starke-Ottich Indra
- Stephan Jörg G.
- Stephens Jessica D.
- Szulc Justyna
- Szulkin Marta
- Tack Ayco J.M.
- Tamburrino Ătalo
- Tate Tayler D.
- Tergemina Emmanuel
- Theodorou Panagiotis
- Thompson Ken A.
- Threlfall Caragh G.
- Tinghitella Robin M.
- Toledo-Chelala Lilibeth
- Tong Alex T.
- Tong Xin
- Uroy LĂ©a
- Utsumi Shunsuke
- Vandegehuchte Martijn L.
- VanWallendael Acer
- Vidal Paula M.
- Wadgymar Susana M.
- Wang Ai Ying
- Wang Nian
- Warbrick Montana L.
- Whitney Kaitlin Stack
- Whitney Kenneth D.
- Wiesmeier Miriam
- Wiles J. Tristian
- Wu Jianqiang
- Xirocostas Zoe A.
- Yan Zhaogui
- Yao Jiahe
- Yoder Jeremy B.
- Yoshida Owen
- Zhang Jingxiong
- Zhao Zhigang
- Ziter Carly D.
- Zuellig Matthew P.
- Zufall Rebecca A.
- Zurita Juan E.
- Zytynska Sharon E.
- Ălvarez Jackie
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 18/03/2022
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre Windsor E.
- Akinwole Philips O.
- Alberti Marina
- Anderson Jill T.
- Anderson Joseph J.
- Ando Yoshino
- Andrew Nigel R.
- Angeoletto Fabio
- Anstett Daniel N.
- Anstett Julia
- Aoki-Gonçalves Felipe
- Arietta A. Z.Andis
- Arroyo Mary T.K.
- Austen Emily J.
- Baena-DĂaz Fernanda
- Barker Cory A.
- Baylis Howard A.
- Beliz Julia M.
- Benitez-Mora Alfonso
- Bickford David
- Biedebach Gabriela
- Blackburn Gwylim S.
- Boehm Mannfred M.A.
- Bonser Stephen P.
- Bonte Dries
- Bragger Jesse R.
- Branquinho Cristina
- Brans Kristien I.
- Bresciano Jorge C.
- Brom Peta D.
- Bucharova Anna
- Burt Briana
- Cahill James F.
- Campbell Katelyn D.
- Carlen Elizabeth J.
- Carmona Diego
- Castellanos Maria Clara
- Centenaro Giada
- Chalen Izan
- Chaves Jaime A.
- Chen Xiao Yong
- Chilton Angela M.
- Chomiak Kristina M.
- ChĂĄvez-Pesqueira Mariana
- Cisneros-Heredia Diego F.
- Cisse Ibrahim K.
- Classen Aimée T.
- Cohan Beata
- Comerford Mattheau S.
- Corney Hannah
- Crawford Andrew J.
- Crawford Kerri M.
- Dahirel Maxime
- David Santiago
- De Haan Robert
- Deacon Nicholas J.
- Dean Clare
- Del-Val Ek
- Deligiannis Eleftherios K.
- Denney Derek
- Dettlaff Margarete A.
- DiLeo Michelle F.
- Ding Yuan Yuan
- Dominoni Davide M.
- DomĂnguez-LĂłpez MoisĂ©s E.
- Draud Savannah L.
- Dyson Karen
- Ellers Jacintha
- Espinosa Carlos I.
- Essi Liliana
- Falahati-Anbaran Mohsen
- FalcĂŁo JĂ©ssica C.F.
- Fargo Hayden T.
- Fellowes Mark D.E.
- Fitzpatrick Connor R.
- Fitzpatrick Raina M.
- Flaherty Leah E.
- Flood PĂĄdraic J.
- Flores MarĂa F.
- Fornoni Juan
- Foster Amy G.
- Fradinger Camila Cordoba
- Frost Christopher J.
- Fuentes Tracy L.
- Fulkerson Justin R.
- Gagnon Edeline
- Garbsch Frauke
- Garroway Colin J.
- Gerstein Aleeza C.
- Giasson Mischa M.
- Girdler E. Binney
- Gkelis Spyros
- Godsoe William
- Golemiec Anneke M.
- Golemiec Mireille
- GonzĂĄlez-Lagos CĂ©sar
- Gorton Amanda J.
- Gotanda Kiyoko M.
- Granath Gustaf
- Greiner Stephan
- Griffiths Joanna S.
- Grilo Filipa
- Gundel Pedro E.
- Hamilton Benjamin
- Hardin Joyce M.
- He Tianhua
- Heard Stephen B.
- Henriques André F.
- HernĂĄndez-Poveda Melissa
- Hetherington-Rauth Molly C.
- Hill Sarah J.
- Hochuli Dieter F.
- Hodgins Kathryn A.
- Hood Glen R.
- Hopkins Gareth R.
- Hovanes Katherine A.
- Howard Ava R.
- Hubbard Sierra C.
- Ibarra-Cerdeña Carlos N.
- Innes Simon G.
- Iñiguez-Armijos Carlos
- Jara-Arancio Paola
- Jarrett Benjamin J.M.
- Jeannot Manon
- Jiménez-Lobato Vania
- Johnson Mae
- Johnson Marc T.J.
- Johnson Oscar
- Johnson Philip P.
- Johnson Reagan
- Josephson Matthew P.
- Jung Meen Chel
- Just Michael G.
- Kahilainen Aapo
- Kailing Otto S.
- Kariñho-Betancourt Eunice
- Karousou Regina
- Kirn Lauren A.
- Kirschbaum Anna
- Koch Sophie
- Laine Anna Liisa
- LaMontagne Jalene M.
- Lampei Christian
- Lara Carlos
- Larson Erica L.
- Le Jennifer H.
- Leandro Deleon S.
- Lee Christopher
- Lei Yunting
- Lequerica Tamara Manuel E.
- Levesque Danica C.
- LeĂłn Carolina A.
- Liao Wan Jin
- Ljubotina Megan
- Locke Hannah
- Lockett Martin T.
- Longo Tiffany C.
- Lundholm Jeremy T.
- LĂĄzaro-Lobo AdriĂĄn
- MacGillavry Thomas
- Mackin Christopher R.
- Mahmoud Alex R.
- Manju Isaac A.
- Mariën Janine
- MartĂnez D. Nayeli
- MartĂnez-BartolomĂ© Marina
- Meineke Emily K.
- Mendoza-Arroyo Wendy
- Merritt Lila Elizabeth L.
- Merritt Thomas J.S.
- Migiani Giuditta
- Miles Lindsay S.
- Minor Emily S.
- Mitchell Nora
- Mohammadi Bazargani Mitra
- Moles Angela T.
- Monk Julia D.
- Moore Christopher M.
- Morales-Morales Paula A.
- Moyers Brook T.
- Munim Samreen
- Munshi-South Jason
- Murphy Shannon M.
- MurĂșa Maureen M.
- Muñoz-Rojas Miriam
- Neila Melisa
- Ness Rob W.
- Nikolaidis Ourania
- NjunjiÄ Iva
- Nosko Peter
- NĂșñez-FarfĂĄn Juan
- Ohgushi Takayuki
- Olsen Kenneth M.
- Opedal Ăystein H.
- Ornelas Cristina
- Parachnowitsch Amy L.
- Paratore Aaron S.
- Parody-Merino Angela M.
- Paule Juraj
- Paulo OctĂĄvio S.
- Pena JoĂŁo Carlos
- Peres-Neto Pedro R.
- Pfeiffer Vera W.
- Pinho Pedro
- Piot Anthony
- Porth Ilga M.
- Poulos Nicholas
- Prashad Cindy
- Puentes Adriana
- Qu Jiao
- Quintero-Vallejo Estela
- Raciti Steve M.
- Raeymaekers Joost A.M.
- Raveala Krista M.
- Rennison Diana J.
- Ribeiro Milton C.
- Richardson Jonathan L.
- Rivas-Torres Gonzalo
- Rivera Benjamin J.
- Roddy Adam B.
- Rodriguez-Muñoz Erika
- RomĂĄn JosĂ© RaĂșl
- Rossi Laura S.
- Rowntree Jennifer K.
- Ryan Travis J.
- Salinas Santiago
- Sanders Nathan J.
- Santangelo James S.
- Santiago-Rosario Luis Y.
- Savage Amy M.
- Scheepens J. F.
- Schilthuizen Menno
- Schneider Adam C.
- Scholier Tiffany
- Scott Jared L.
- Shaheed Summer A.
- Shefferson Richard P.
- Shepard Caralee A.
- Shykoff Jacqui A.
- Silveira Georgianna
- Smith Alexis D.
- Solis-Gabriel Lizet
- Soro Antonella
- Spellman Katie V.
- Starke-Ottich Indra
- Stephan Jörg G.
- Stephens Jessica D.
- Szulc Justyna
- Szulkin Marta
- Tack Ayco J.M.
- Tamburrino Ătalo
- Tate Tayler D.
- Tergemina Emmanuel
- Theodorou Panagiotis
- Thompson Ken A.
- Threlfall Caragh G.
- Tinghitella Robin M.
- Toledo-Chelala Lilibeth
- Tong Alex T.
- Tong Xin
- Uroy LĂ©a
- Utsumi Shunsuke
- Vandegehuchte Martijn L.
- VanWallendael Acer
- Vidal Paula M.
- Wadgymar Susana M.
- Wang Ai Ying
- Wang Nian
- Warbrick Montana L.
- Whitney Kaitlin Stack
- Whitney Kenneth D.
- Wiesmeier Miriam
- Wiles J. Tristian
- Wu Jianqiang
- Xirocostas Zoe A.
- Yan Zhaogui
- Yao Jiahe
- Yoder Jeremy B.
- Yoshida Owen
- Zhang Jingxiong
- Zhao Zhigang
- Ziter Carly D.
- Zuellig Matthew P.
- Zufall Rebecca A.
- Zurita Juan E.
- Zytynska Sharon E.
- Ălvarez Jackie
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 18/03/2022
- Field of study
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre Windsor E
- Akinwole , Philips O
- Alberti Marina
- Anderson Jill T
- Anderson Joseph J
- Andis Arietta A Z
- Ando Yoshino
- Andrew Nigel R
- Angeoletto Fabio
- Anstett Daniel N
- Anstett Julia
- Aoki-Gonçalves Felipe
- Arroyo Mary T K
- Austen Emily J
- Baena-DĂaz Fernanda
- Barker Cory A
- Baylis Howard A
- Bazargani Mitra Mohammadi
- Beliz Julia M
- Benitez-Mora Alfonso
- Bickford David
- Biedebach Gabriela
- Blackburn Gwylim S
- Boehm Mannfred M A
- Bonser Stephen P
- Bonte Dries
- Bragger Jesse R
- Branquinho Cristina
- Brans Kristien I
- Bresciano Jorge C
- Brom Peta D
- Bucharova Anna
- Burt Briana
- Cahill James F
- Campbell Katelyn D
- Carlen Elizabeth J
- Carmona Diego
- Castellanos Maria C
- Centenaro Giada
- Chalen Izan
- Chaves Jaime A
- Chen Xiao-Yong
- Chilton Angela M
- Chomiak Kristina M
- ChĂĄvez-Pesqueira Mariana
- Cisneros-Heredia Diego F
- Cisse Ibrahim K
- Classen Aimée T
- Cohan Beata
- Comerford Mattheau S
- Corney Hannah
- Crawford Kerri M
- Crawford Andrew J
- Dahirel Maxime
- David Santiago
- De Haan Robert
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- Dean Clare
- del-Val Ek
- Deligiannis Eleftherios K
- Denney Derek
- Dettlaff Margarete A
- DiLeo Michelle F
- Ding Yuan-Yuan
- Dominoni Davide M
- DomĂnguez-LĂłpez MoisĂ©s E
- Draud Savannah L
- Dyson Karen
- Ellers Jacintha
- Espinosa Carlos I
- Essi Liliana
- Falahati-Anbaran Mohsen
- FalcĂŁo JĂ©ssica C F
- Fargo Hayden T
- Fellowes Mark D E
- Fitzpatrick Connor R
- Fitzpatrick Raina M
- Flaherty Leah E
- Flood PĂĄdraic J
- Flores MarĂa F
- Fornoni Juan
- Foster Amy G
- Fradinger Camila Cordoba
- Frost Christopher J
- Fuentes Tracy L
- Fulkerson Justin R
- Gagnon Edeline
- Garbsch Frauke
- Garroway Colin J
- Gerstein Aleeza C
- Giasson Mischa M
- Girdler E Binney
- Gkelis Spyros
- Godsoe William
- Golemiec Anneke M
- Golemiec Mireille
- GonzĂĄlez-Lagos CĂ©sar
- Gorton Amanda J
- Gotanda Kiyoko M
- Granath Gustaf
- Greiner Stephan
- Griffiths Joanna S
- Grilo Filipa
- Gundel Pedro E
- Hamilton Benjamin
- Hardin Joyce M
- He Tianhua
- Heard Stephen B
- Henriques André F
- HernĂĄndez-Poveda Melissa
- Hetherington-Rauth Molly C
- Hill Sarah J
- Hochuli Dieter F
- Hodgins Kathryn A
- Hood Glen R
- Hopkins Gareth R
- Hovanes Katherine A
- Howard Ava R
- Hubbard Sierra C
- Ibarra-Cerdeña Carlos N
- Innes Simon G
- Iñiguez-Armijos Carlos
- Jara-Arancio Paola
- Jarrett Benjamin J M
- Jeannot Manon
- Jiménez-Lobato Vania
- Johnson Mae
- Johnson Marc T J
- Johnson Oscar
- Johnson Philip P
- Johnson Reagan
- Josephson Matthew P
- Jung Meen Chel
- Just Michael G
- Kahilainen Aapo
- Kailing Otto S
- Kariñho-Betancourt Eunice
- Karousou Regina
- Kirn Lauren A
- Kirschbaum Anna
- Koch Sophie
- Laine Anna-Liisa
- LaMontagne Jalene M
- Lampei Christian
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- Le Jennifer H
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- Levesque Danica C
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- Ljubotina Megan
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- Lundholm Jeremy T
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- Mahmoud Alex R
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- Mendoza-Arroyo Wendy
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- Merritt Thomas J S
- Migiani Giuditta
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- Mitchell Nora
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- Monk Julia D
- Moore Christopher M
- Morales-Morales Paula A
- Moyers Brook T
- Munim Samreen
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- MurĂșa Maureen M
- Muñoz-Rojas Miriam
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- Neila Melisa
- Ness Rob W
- Nikolaidis Ourania
- Njunji Iva
- Nosko Peter
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- Ohgushi Takayuki
- Olsen Kenneth M
- Opedal Ăystein H
- Ornelas Cristina
- Parachnowitsch Amy L
- Paratore Aaron S
- Parody-Merino Angela M
- Paule Juraj
- Paulo OctĂĄvio S
- Pena JoĂŁo Carlos
- Peres-Neto Pedro R
- Pfeiffer Vera W
- Pinho Pedro
- Piot Anthony
- Porth Ilga M
- Poulos Nicholas
- Prashad Cindy
- Puentes Adriana
- Qu Jiao
- Quintero-Vallejo Estela
- Raciti Steve M
- Raeymaekers Joost A M
- Raveala Krista M
- Rennison Diana J
- Ribeiro Milton C
- Richardson Jonathan L
- Rivas-Torres Gonzalo
- Rivera Benjamin J
- Roddy Adam B
- Rodriguez-Muñoz Erika
- RomĂĄn JosĂ© RaĂșl
- Rossi Laura S
- Rowntree Jennifer K
- Ryan Travis J
- Salinas Santiago
- Sanders Nathan J
- Santangelo James S
- Santiago-Rosario Luis Y
- Savage Amy M
- Scheepens J F
- Schilthuizen Menno
- Schneider Adam C
- Scholier Tiffany
- Scott Jared L
- Shaheed Summer A
- Shefferson Richard P
- Shepard Caralee A
- Shykoff Jacqui A
- Silveira Georgianna
- Smith Alexis D
- Solis-Gabriel Lizet
- Soro Antonella
- Spellman Katie V
- Starke-Ottich Indra
- Stephan Jörg G
- Stephens Jessica D
- Szulc Justyna
- Szulkin Marta
- Tack Ayco J M
- Tamburrino Ătalo
- Tate Tayler D
- Tergemina Emmanuel
- Theodorou Panagiotis
- Thompson Ken A
- Threlfall Caragh G
- Tinghitella Robin M
- Toledo-Chelala Lilibeth
- Tong Alex T
- Tong Xin
- Tristian Wiles J
- Uroy LĂ©a
- Utsumi Shunsuke
- Vandegehuchte Martijn L
- VanWallendael Acer
- Vidal Paula M
- Wadgymar Susana M
- Wang Ai-Ying
- Wang Nian
- Warbrick Montana L
- Whitney Kaitlin Stack
- Whitney Kenneth D
- Wiesmeier Miriam
- Wu Jianqiang
- Xirocostas Zoe A
- Yan Zhaogui
- Yao Jiahe
- Yoder Jeremy B
- Yoshida Owen
- Zhang ingxiong
- Zhao Zhigang
- Ziter Carly D
- Zuellig Matthew P
- Zufall Rebecca A
- Zurita Juan E
- Zytynska Sharon E
- Ălvarez Jackie
- Publication venue
- American Association for the Advancement of Science (AAAS)
- Publication date
- 25/10/2023
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Reduction of cardiac imaging tests during the COVID-19 pandemic: The case of Italy. Findings from the IAEA Non-invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)
- Author
- Abdelkader Medjahedi
- Adam Bernheim
- Adel Allam
- Adelina Sanches
- Aditya Sood
- Adna Lima
- Adolfo Facello
- Adriana Puente Barragan
- Adwait Trivedi
- Afonso Shiozaki
- Agha Haider
- AgnĂšs Pasquet
- Ahmad Mansy
- Ahmad Ozair
- Ahmad Slim
- Ahmed Asfour
- Ahmed Ibrahim
- Ahmed Kandeel
- Ahmed Tawakol
- Aikaterini Archontaki
- Alan Goldberg
- Alastair Moss
- Alberico Del Torto
- Albert Flotats
- Albert T
- Alberto Cadena
- Alberto Cossu
- Alberto Cuocolo
- Aldo Carnevale
- Alejandra Marquez
- Alejandro Becerril GonzĂĄlez-Montecinos
- Alejandro Canderoli
- Alejandro De La Vega
- Alejandro Deviggiano
- Alejandro Horacio Meretta
- Alejandro Radzinschi
- Alejandro Zuluaga Costa Rica: Isabel Berrocal Gamboa
- Alessia Gimelli
- Alex Frenkel
- Alexander Kokov
- Alexander Pitman
- Alexander Sasse
- Alexandra Smith
- Alexia Farrugia
- Alfonso Waller
- Alfredo Astesiano
- Alfredo Rodrigues
- Alia Hassan
- Alicia Camarero
- Alistair Gummow
- Alix Juillet de Saint Lager Lucas
- Allan Johansen
- Alvin Quinon
- Amalia Peix
- Amanda Marn
- Ambedhkar Shantaram Naojee Mexico: Erick Alexanderson-Rosas
- Amelia Jimenez-Heffernan
- Ami Iskandrian
- Amit Patel
- Amit Pursnani
- Ana Sevilla
- Anand Gaikwad
- Anastasia Oikonomou
- Anatoly Karalkin
- Anda Bularga
- Anders Thomassen
- Anders Tjellaug BrÄten Oman: Humoud Al Dhuhli
- Andor Glaudemans
- Andrea Astesiano
- Andrea Bruno
- Andrea De Lorenzo
- Andres Vasquez
- Andressa Borges
- Andrew Choi
- Andrew Kelion
- Andrew Taylor
- Andrew To
- Andrés Preciado-Anaya
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- Croatia: Ana Baric
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- Djibrillou Moussa Issoufou Nigeria: Tolulope Ayodele
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- Dominique Dabreo
- Donald Chang
- Donatas Vajauskas Luxembourg: Christian Picard Malaysia: Noor Khairiah A. Karim Malta: Luise Reichmuth
- Dondi M.
- Dong Li
- Dorbala S.
- Duane Chambers
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- Edison Edison
- Edit VĂĄrady India: Nilesh Banthia
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- Felix Nunura Japan: Hiroshi Asano
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- Fernando de Amorim Fernandes
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- Fernando Kay
- Fernando Mendoza
- Fernando Mut Uzbekistan: Omoa Djuraev
- Filiberto Cortés
- Filip Homans
- Filipe Penna De Carvalho
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- Florence Rich
- Floyd W. Burke
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- Gabriel Blacher Grossman
- Gabriel Castro
- Gabriel Castro Muñoz
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- Galit Knafo
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- Gary Small
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- George Bennie
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- Gerrit Engelbrecht
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- Giampiero Longo
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- Giedre Kviecinskiene
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- Guilhermina Cantinho
- Guillermo Arroñada
- Gulnora Rozikhodjaeva Vietnam: Ha Le Ngoc
- Gustavo Raimondi
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- Habusari Hapkido
- Haluk Sayman Uganda: Mugisha Julius Sebikali
- Hamid Salehi
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- Harlem Gongxeka
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- Hector Bladimir Roque Vanegas Niger: Idrissa Adamou Soli
- Henry Bom
- Hideki Otsuka
- Hilman Syawaluddin Iraq: Amjed Albadr Islamic Republic of Iran: Majid Assadi
- Hiram Rivera Luna
- Hiroki Teragawa
- Hirotaka Maruno
- Hiroyuki Mataki
- Hirschfeld C. B.
- Hoosen Lakhi
- Horacio Del Riego
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- Hui Liu
- Husam Farah
- Ian Swainson
- Ibraim Pinto
- Idan Roifman
- Ilan Gottlieb
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- Imre Benedek
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- Ioannis Petrou Czech Republic: Vaclav Engelmann
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- Irina Itskovich
- Irina Shurupova
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- Isabel Carvajal-Juarez
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- Italy: Domenico Albano
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- Jamshid Shirani
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- Jay Layer
- Jean Engela
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- Jeffrey Askew
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- Jennifer Calcott
- Jennifer Chen
- Jeremy Markowitz
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- Jerry Obaldo
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- Jessica Brothers
- Ji-Young Kim
- Jia Hao Jason See
- Jian Wang
- Jiang Wu
- Jiangxi Xiao
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- Jinendra Kumar Bhagat
- Jinkang Liu
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- Johan Verjans
- Johanne Neill
- John Dougan
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- John Murray
- John O. Prior
- John Rumberger
- John Younger Austria: Gudrun Feuchtner
- John-Paul Carpenter
- Jolanta Kunikowska Portugal: Nuno Bettencourt
- Jon Martin
- Jonathan Carl Luis Rodrigues
- Jonathan Shulman
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- Jonathon Leipsic
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- José Claudio Meneghetti
- José Ortellado People's Republic of Bangladesh: Afroza Akhter People's Republic of China: Dianbo Cao
- José Soares Junior
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Background: In early 2020, COVID-19 massively hit Italy, earlier and harder than any other European country. This caused a series of strict containment measures, aimed at blocking the spread of the pandemic. Healthcare delivery was also affected when resources were diverted towards care of COVID-19 patients, including intensive care wards. Aim of the study: The aim is assessing the impact of COVID-19 on cardiac imaging in Italy, compare to the Rest of Europe (RoE) and the World (RoW). Methods: A global survey was conducted in MayâJune 2020 worldwide, through a questionnaire distributed online. The survey covered three periods: March and April 2020, and March 2019. Data from 52 Italian centres, a subset of the 909 participating centres from 108 countries, were analyzed. Results: In Italy, volumes decreased by 67% in March 2020, compared to March 2019, as opposed to a significantly lower decrease (p < 0.001) in RoE and RoW (41% and 40%, respectively). A further decrease from March 2020 to April 2020 summed up to 76% for the North, 77% for the Centre and 86% for the South. When compared to the RoE and RoW, this further decrease from March 2020 to April 2020 in Italy was significantly less (p = 0.005), most likely reflecting the earlier effects of the containment measures in Italy, taken earlier than anywhere else in the West. Conclusions: The COVID-19 pandemic massively hit Italy and caused a disruption of healthcare services, including cardiac imaging studies. This raises concern about the medium- and long-term consequences for the high number of patients who were denied timely diagnoses and the subsequent lifesaving therapies and procedures
Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
- Author
- A.A. Essam
- A.B. Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman K.Z. Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B. Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adewale Adeniyi
- Adewale O. Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M. Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
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- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
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- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yakubu Momohsani Adinoyi
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos BermĂșdez
- Yucel Cengiz
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas UrnieĆŸius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ămer Faruk Toto
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/09/2023
- Field of study
Background: This study assessed the potential cost-effectiveness of high (80â100%) vs low (21â35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods: Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing the effectiveness of high FiO2, published literature, and a cost survey in Nigeria, India, and South Africa. Effectiveness was measured as percentage of SSIs at 30 days after surgery, a healthcare perspective was adopted, and costs were reported in US dollars ().Results:HighFiO2maybecostâeffective(cheaperandeffective).InNigeria,theaveragecostforhighFiO2was216 compared with 222forlowFiO2leadingtoa â6 (95% confidence interval [CI]: â13to â1) difference in costs. In India, the average cost for high FiO2 was 184comparedwith195 for low FiO2 leading to a â11(9515 to â6)differenceincosts.InSouthAfrica,theaveragecostforhighFiO2was1164 compared with 1257forlowFiO2leadingtoa â93 (95% CI: â132to â65) difference in costs. The high FiO2 arm had few SSIs, 7.33% compared with 8.38% for low FiO2, leading to a â1.05 (95% CI: â1.14 to â0.90) percentage point reduction in SSIs. Conclusion: High FiO2 could be cost-effective at preventing SSIs in the three countries but further data from large clinical trials are required to confirm this
Use of Telemedicine for Post-discharge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review with Meta-analysis
- Author
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji Ademuyiwa
- Adesoji O Ademuyiwa
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale Adisa
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat PektaĆ
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de LeĂłn
- Alberto PeĂłn
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alisha Bhatt
- Alissa GĂŒbeli
- Alistair Rocke
- Aliyu Ndajiwo
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
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- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amar Kourdouli
- Amgad Al Meligy
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- Aminu Mohammad Samson Olori
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- Andre Navarro
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- Antoinette Bediako-Bowan
- Antonella La Brocca
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- Arturas Vaicius
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- Arvo Reinsoo
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- Ashraf Maghrabi
- Ashrafun Nessa
- Ashrarur Rahman Mitul
- Ashwath Bandi
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- Asnel Dorismé
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- Astrid Leusink
- Ataa Ahmed
- Athanasia Bamicha
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- Athula Tennakoon
- Attia Attia
- Audrey Clarissa
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- Beatrice Brunoni
- Behrad Barmayehvar
- Belen Sanchez
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- Bernard Limoges
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- Bertrand Dousset
- Besmir Grizhja
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- Bettina Lieske
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- Bryar Kadir
- Busra Murutoglu
- BĂĄrbara MĂĄlaga
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- Choon Seng Chong
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- Choy Ling Tan
- Chris Bode
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- Christine Mizzi
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- Rupert Pearse
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- S P B Thalgaspitiya
- Saban Celik
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- Sabine Irtan
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- Safia Ali
- Saged Elsherbiney
- Sahar Jaber
- Saiba Abdul-Latif
- Said Alyacoubi
- Sakhaa Hanoun
- Saleh Alqahtani
- Salma Magdy
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- Salwa Khallaf
- Sam Debrah
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- Samah Afana
- Samantha Corro-Diaz
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- Samar Soliman
- Sameer Kushwaha
- Sameh Emile
- Sameh Farag
- Samuel Essoun
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- Samuel S Y Sii
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- Sandra Ahlqvist
- Sandra Ahlqvist
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- Sara Mamdouh Matter
- Sara Mohammed
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- Sophian Hmila
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- Stefano Giuliani
- Stefano M M Basso
- Sten Saar
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- Stephen Knight
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- Stephen Tabiri
- Stephen Tabiri
- Stephen Tabiri
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- Sunil Kumar
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- Syed Abdul Wahhab Eusoffee Wan Ali
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- Sylvia Kamya
- Sylvie Mochet
- Syrine Rekhis
- T Ariani Widiastini
- Taha Yusufali
- Taher Al-Taher
- Taiwo Lawal
- Talar Vartanoglu
- Tamara Diaz Vico
- Tanzeela Gala
- Tanzeela Gala
- Tara Grima
- Tarek Ezzat
- Tariq Alhammali
- Tasnia Hamid Kanta
- Tatsiana Shachykava
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- Tewodros Worku
- Thamer Nouh
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- Thelma Tembo
- Theodore Pezas
- Theodosios Theodosopoulos
- Therese Duane
- Thierry Alihonou
- Thomas Feidantsis
- Thomas Kidd
- Thomas M Drake
- Thomas Mann
- Thomas Olagboyega Olajide
- Thomas Pinkney
- Thomas Pinkney
- Thomas Prudhomme
- Thomas Tetens Moe
- Tien Seng Bryan Lee
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Abbott
- Tom Arthur
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poskus
- Tomas Poskus
- Tomas PoĆĄkus
- Tomas Urbonas
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Toqa Khafagy
- Torhild Veen
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tubasiime Ronald
- Tunde Sholadoye
- Turgut Bora Cengiz
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uttaran Datta
- Vahit Mutlu
- Valdemaras Jotautas
- Valeria Andriola
- Vanessa Msosa
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Kalles
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Vedatcan IĆler
- Veeranna Shatkar
- Venerand Barendegere
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Nwinee
- Victoria Adeyeye
- Vijaid Upadhyaya
- Viktorija Nevieraite
- Ville Sallinen
- Vincas Jonas Banaitis
- Virginia Jiménez Carneros
- Virginia Ramos PĂ©rez
- Viviana Sollazzo
- Vladimir Khokha
- Volkan Ozben
- Vu Thanh Hien Le
- Vytautas GaiĆŸauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong Kuhaendran Gunaseelan
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda Tasneem Idress
- Ysabel Esthefany Alejos BermĂșdez
- Yucel Cengiz
- Yucel Cengiz Dmitri Raptis
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas UrnieĆŸius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ămer Faruk Toto
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2022
- Field of study
Objective: This study aimed to determine whether remote wound reviews using telemedicine can be safely upscaled, and if standardised assessment tools are needed. Summary background data: Surgical site infection is the most common complication of surgery worldwide, and frequently occurs after hospital discharge. Evidence to support implementation of telemedicine during postoperative recovery will be an essential component of pandemic recovery. Methods: The primary outcome of this study was surgical site infection reported up to 30-days after surgery (SSI), comparing rates reported using telemedicine (telephone and/or video assessment) to those with in-person review. The first part of this study analysed primary data from an international cohort study of adult patients undergoing abdominal surgery who were discharged from hospital before 30-days after surgery. The second part combined this data with the results of a systematic review to perform a meta-analysis of all available data conducted in accordance with PRIMSA guidelines (PROSPERO:192596). Results: The cohort study included 15,358 patients from 66 countries (8069 high, 4448 middle, 1744 low income). Of these, 6907 (45.0%) were followed up using telemedicine. The SSI rate reported using telemedicine was slightly lower than with in-person follow-up (13.4% vs. 11.1%, P<0.001), which persisted after risk adjustment in a mixed-effects model (adjusted odds ratio: 0.73, 95% confidence interval 0.63-0.84, P<0.001). This association was consistent across sensitivity and subgroup analyses, including a propensity-score matched model. In nine eligible non-randomised studies identified, a pooled mean of 64% of patients underwent telemedicine follow-up. Upon meta-analysis, the SSI rate reported was lower with telemedicine (odds ratio: 0.67, 0.47-0.94) than in-person (reference) follow-up (I2=0.45, P=0.12), although there a high risk of bias in included studies. Conclusions: Use of telemedicine to assess the surgical wound post-discharge is feasible, but risks underreporting of SSI. Standardised tools for remote assessment of SSI must be evaluated and adopted as telemedicine is upscaled globally
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- AbellĂĄn Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Ăzlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia GonzĂĄlez
- Aleem Muhammad
- Alegre InĂȘs
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz AmorĂłs
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-DĂez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado FabĂola
- Amador Cristina GarcĂa
- Amanullah Nazli
- Amaral HĂ©lida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- AndrĂ©s Beatriz DĂaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- AĆkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia FernĂĄndez
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel SĂĄnchez
- Bayhan ZĂŒlfĂŒ
- Bayo José Manuel Muros
- BayĂłn Raquel Ălvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- BeltrĂĄn de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
- Benkabbou Amine
- Bennett James
- Bensafir Salim
- Bergamini Carlo
- Bernotaite Vlada
- Beron Reinaldo Isaacs
- Bethune Robert
- Bezede Cosmin
- Beznosenko Andriy
- Bhangu Aneel
- Bhargava Aman
- Bhat Rama Rani Krishna
- Bianchi Romina
- Bianco Francesco
- Bigoni Irene
- Binetti Margherita
- Bintintan Vasile
- Biondi Alberto
- Biondo Santino Antonio
- Bisgin Tayfun
- Bisheet George
- Bissett Ian
- Biswas Jyotirmoy
- Blackwell Sue
- Blanco Pablo
- Blanco Raquel RĂos
- Blanco-Colino Ruth
- Blasco Laura Fraile
- Blazquez-Martin Alma
- Bobadilla Billy Jimenez
- Bocancia Raluca
- Boccia Giuseppe
- Bogatikov Alexander
- Bolanle Olajide Edward
- Bomfa-Barbosa Alysson
- Bompou Effrosyni
- Bonardello Michela
- Bonci Eduard-Alexandru
- Bordom Daniel Osei
- Borges Filipe
- Borghi Felice
- Boschiero Matheus Negri
- Bose Bodhisattva
- Bouchagier Konstantinos
- Boudjenan-Serradj Nabil
- Boudoux Sabrina
- Bourazani Maria
- Boyce Stephen
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bradulskis Saulius
- Brainsa Eneida
- Brandström Gustav
- Braumille Markus
- Bravo Ana Minaya
- Bravo Raquel
- Bredikhin Mikhail
- Brito Noelia
- Bruni Andrea
- Buccianti Piero
- Buchs Nicolas
- Buchwald Pamela
- Budnikova Ina
- BudrikienÄ Rima
- Buey Lourdes
- Buijs Louis
- Buleje Jorge Alejandro Benavides
- Burlov Nikita
- Butt Anam
- Byshetty Rajendar
- Bywater Edward
- Bzikha Ilham
- BĂĄnky BalĂĄzs
- BĂŠlum Jens Kristian
- Caballero-Delgado Javier
- Cabrera Claudia
- Cafranga EstĂbaliz GutiĂ©rrez
- Cagnazzo Federica
- Calabria Mariangela
- Calabro' Marcello
- Caliendo Domenico
- Calin Camelia
- Caliskan Cemil
- Callan Rory
- Callari Cosimo
- Caltea Mihaela
- Calvo Almudena Castro
- Camacho Amparo
- Cammarata Francesco
- Campanati Renato
- Campanelli Michela
- Campbell Marion
- Canals LucĂa Otazu
- Canda Aras Emre
- Cano-Matias Auxiliadora
- Cao Victor Hugo Bruno
- Capolupo Gabriella Teresa
- Cappiello Antonio
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- Yew Chor Kuan
- Yılmaz GĂŒlseren
- Yilmazlar Tuncay
- YiÄit Direnç
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- ZadroĆŒna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah KaÄan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Ălvarez-Llano Laura
- Ăngelo Miguel Duarte
- ĂSullivan Sara Nuñez
- Ăzçelik Mehmet Faik
- Äoza Ivo
- Ćanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)