103 research outputs found
Inflation Reduction Act impacts on the economics of clean hydrogen and liquid fuels
The Inflation Reduction Act (IRA) in the United States provides unprecedented
incentives for deploying low-carbon hydrogen and liquid fuels, among other low
greenhouse gas (GHG) emissions technologies. To better understand the
prospective competitiveness of low-carbon or negative-carbon hydrogen and
liquid fuels under the IRA in the early 2030s, we examine the impacts of IRA
provisions on costs of producing hydrogen and synthetic liquid fuel made from
natural gas, electricity, short-cycle biomass (agricultural residues), and
corn-ethanol. With IRA credits (45V or 45Q), but excluding incentives provided
by other national or state policies, hydrogen produced by electrolysis using
carbon-free electricity (green H2) and natural gas reforming with carbon
capture and storage (CCS) (blue H2) are cost-competitive with the
carbon-intensive benchmark gray H2 from steam methane reforming.
Biomass-derived H2 with or without CCS is not cost-completive under current IRA
provisions. However, if IRA allowed biomass gasification with CCS to claim a
45V credit for carbon-neutral H2 and a 45Q credit for negative biogenic-CO2
emissions, this pathway would be less costly than gray H2. The IRA credit for
clean fuels (45Z), currently stipulated to end in 2027, would need to be
extended, or similar policy support provided by other national or state
policies, for clean synthetic liquid fuel to be cost-competitive with
petroleum-derived liquid fuels. Levelized IRA subsidies per unit of CO2
mitigated for all hydrogen and synthetic liquid fuel production pathways,
except electricity-derived synthetic liquid fuel, range from 65 to 384 $/t CO2,
which is within or below the range in U.S. federal government estimates of the
Social Cost of Carbon (SCC) in the 2030 to 2040 timeframe
A First Comparison of Kepler Planet Candidates in Single and Multiple Systems
In this letter we present an overview of the rich population of systems with
multiple candidate transiting planets found in the first four months of Kepler
data. The census of multiples includes 115 targets that show 2 candidate
planets, 45 with 3, 8 with 4, and 1 each with 5 and 6, for a total of 170
systems with 408 candidates. When compared to the 827 systems with only one
candidate, the multiples account for 17 percent of the total number of systems,
and a third of all the planet candidates. We compare the characteristics of
candidates found in multiples with those found in singles. False positives due
to eclipsing binaries are much less common for the multiples, as expected.
Singles and multiples are both dominated by planets smaller than Neptune; 69
+2/-3 percent for singles and 86 +2/-5 percent for multiples. This result, that
systems with multiple transiting planets are less likely to include a
transiting giant planet, suggests that close-in giant planets tend to disrupt
the orbital inclinations of small planets in flat systems, or maybe even to
prevent the formation of such systems in the first place.Comment: 13 pages, 13 figures, submitted to ApJ Letter
Inherited germline TP53 mutation encodes a protein with an aberrant C-terminal motif in a case of pediatric adrenocortical tumor
Childhood adrenocortical tumor (ACT), a very rare malignancy, has an annual worldwide incidence of about 0.3 per million children younger than 15Â years. The association between inherited germline mutations of the TP53 gene and an increased predisposition to ACT was described in the context of the Li-Fraumeni syndrome. In fact, about two-thirds of children with ACT have a TP53 mutation. However, less than 10% of pediatric ACT cases occur in Li-Fraumeni syndrome, suggesting that inherited low-penetrance TP53 mutations play an important role in pediatric adrenal cortex tumorigenesis. We identified a novel inherited germline TP53 mutation affecting the acceptor splice site at intron 10 in a child with an ACT and no family history of cancer. The lack of family history of cancer and previous information about the carcinogenic potential of the mutation led us to further characterize it. Bioinformatics analysis showed that the non-natural and highly hydrophobic C-terminal segment of the frame-shifted mutant p53 protein may disrupt its tumor suppressor function by causing misfolding and aggregation. Our findings highlight the clinical and genetic counseling dilemmas that arise when an inherited TP53 mutation is found in a child with ACT without relatives with Li-Fraumeni-component tumors
The Kepler Science Data Processing Pipeline Source Code Road Map
We give an overview of the operational concepts and architecture of the Kepler Science Processing Pipeline. Designed, developed, operated, and maintained by the Kepler Science Operations Center (SOC) at NASA Ames Research Center, the Science Processing Pipeline is a central element of the Kepler Ground Data System. The SOC consists of an office at Ames Research Center, software development and operations departments, and a data center which hosts the computers required to perform data analysis. The SOC's charter is to analyze stellar photometric data from the Kepler spacecraft and report results to the Kepler Science Office for further analysis. We describe how this is accomplished via the Kepler Science Processing Pipeline, including, the software algorithms. We present the high-performance, parallel computing software modules of the pipeline that perform transit photometry, pixel-level calibration, systematic error correction, attitude determination, stellar target management, and instrument characterization
Range-wide sources of variation in reproductive rates of northern spotted owls
We conducted a range-wide investigation of the dynamics of site-level reproductive rate of northern spotted owls using survey data from 11 study areas across the subspecies geographic range collected during 1993â2018. Our analytical approach accounted for imperfect detection of owl pairs and misclassification of successful reproduction (i.e., at least one young fledged) and contributed further insights into northern spotted owl population ecology and dynamics. Both nondetection and state misclassification were important, especially because factors affecting these sources of error also affected focal ecological parameters. Annual probabilities of site occupancy were greatest at sites with successful reproduction in the previous year and lowest for sites not occupied by a pair in the previous year. Site-specific occupancy transition probabilities declined over time and were negatively affected by barred owl presence. Overall, the site-specific probability of successful reproduction showed substantial year-to-year fluctuations and was similar for occupied sites that did or did not experience successful reproduction the previous year. Site-specific probabilities for successful reproduction were very small for sites that were unoccupied the previous year. Barred owl presence negatively affected the probability of successful reproduction by northern spotted owls in Washington and California, as predicted, but the effect in Oregon was mixed. The proportions of sites occupied by northern spotted owl pairs showed steep, near-monotonic declines over the study period, with all study areas showing the lowest observed levels of occupancy to date. If trends continue it is likely that northern spotted owls will become extirpated throughout large portions of their range in the coming decades
The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism
Crassulacean acid metabolism (CAM) is a water-use efficient adaptation of photosynthesis that has evolved independently many times in diverse lineages of flowering plants. We hypothesize that convergent evolution of protein sequence and temporal gene expression underpins the independent emergences of CAM from C3 photosynthesis. To test this hypothesis, we generate a de novo genome assembly and genome-wide transcript expression data for KalanchoĂ« fedtschenkoi, an obligate CAM species within the core eudicots with a relatively small genome (~260âMb). Our comparative analyses identify signatures of convergence in protein sequence and re-scheduling of diel transcript expression of genes involved in nocturnal CO2 fixation, stomatal movement, heat tolerance, circadian clock, and carbohydrate metabolism in K. fedtschenkoi and other CAM species in comparison with non-CAM species. These findings provide new insights into molecular convergence and building blocks of CAM and will facilitate CAM-into-C3 photosynthesis engineering to enhance water-use efficiency in crops
A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome
Citation: Chapman, J. A., Mascher, M., Buluç, A., Barry, K., Georganas, E., Session, A., . . . Rokhsar, D. S. (2015). A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome. Genome Biology, 16(1). doi:10.1186/s13059-015-0582-8Polyploid species have long been thought to be recalcitrant to whole-genome assembly. By combining high-throughput sequencing, recent developments in parallel computing, and genetic mapping, we derive, de novo, a sequence assembly representing 9.1 Gbp of the highly repetitive 16 Gbp genome of hexaploid wheat, Triticum aestivum, and assign 7.1 Gb of this assembly to chromosomal locations. The genome representation and accuracy of our assembly is comparable or even exceeds that of a chromosome-by-chromosome shotgun assembly. Our assembly and mapping strategy uses only short read sequencing technology and is applicable to any species where it is possible to construct a mapping population. © 2015 Chapman et al. licensee BioMed Central.Additional Authors: Muehlbauer, G. J.;Stein, N.;Rokhsar, D. S
Digestion of fatty acids in ruminants: a meta-analysis of flows and variation factors. 1. Total fatty acids
TRY plant trait database â enhanced coverage and open access
Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of traitâbased plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for âplant growth formâ. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and traitâenvironmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
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