Hawaiʻi’s College of Tropical Agriculture and Human Resources : celebrating the first 100 years

These histories are taken from the 2008 publication entitled Hawai‘i’s College of Tropical Agriculture and Human Resources -- Celebrating the First 100 Years

Rents and entitlements: reassessing Africa’s urban pasts and futures

This article considers recent literature on contemporary urbanization in Africa that is united in its 'post-normative' orientation, firmly discarding the 'expectations' of modernization that so deeply shaped twentieth-century research on African cities. Best typified by the work of urban anthropologists such as Abdoumaliq Simone, this scholarship instead focuses on the 'vernacularization' of urban structures and strategies in Africa. While such work has developed a host of new insights into the idiosyncratic nature of African urbanization, it has largely eschewed comparative analysis of enduring economic strategies that lie at the heart of the massive growth of African cities. By focusing on the longer-term historical role of such processes – namely urban rents and urban price regulations – this article suggests a more comparative framework for the study of urban Africa that still accounts for the otherwise seemingly hyper-local and idiosyncratic forms of urban livelihoods and strategies. Key words: urban history, urbanization, consumption, rent, price control

The Open Navigation Surface Project

Many hydrographic and oceanographic agencies have moved or are moving towards gridded bathymetric products. However, there is no accepted format to allow these grids to be exchanged while maintaining data and metadata integrity. This paper describes the Open Navigation Surface (ONS) Project, which aims to fill this gap. The ONS Project is an open-source software project designed to provide a freely available, portable source-code library to encapsulate gridded bathymetric surfaces with associated uncertainty values. The data file format is called a Bathymetric Attributed Grid (BAG). The BAG is developed and maintained by the ONS Working Group (ONSWG), and the source code is available via the ONS websit

Voluntary wheel running augments aortic L-arginine transport and endothelial function in rats with chronic kidney disease

Reduced nitric oxide (NO) synthesis contributes to risk for cardiovascular disease in chronic kidney disease (CKD). Vascular uptake of the NO precursor L-arginine (ARG) is attenuated in rodents with CKD, resulting in reduced substrate availability for NO synthesis and impaired vascular function. We tested the effect of 4 wk of voluntary wheel running (RUN) and/or ARG supplementation on endothelium-dependent relaxation (EDR) in rats with CKD. Twelve-week-old male Sprague-Dawley rats underwent 5/6 ablation infarction surgery to induce CKD, or SHAM surgery as a control. Beginning 4 wk following surgery, CKD animals either remained sedentary (SED) or received one of the following interventions: supplemental ARG, RUN, or combined RUN + ARG. Animals were euthanized 8 wk after surgery, and EDR was assessed. EDR was significantly impaired in SED vs. SHAM animals after 8 wk, in response to ACh (10(-9)-10(-5) M) as indicated by a reduced area under the curve (AUC; 44.56 +/- 9.01 vs 100 +/- 4.58, P \u3c 0.05) and reduced maximal response (E-max; 59.9 +/- 9.67 vs. 94.31 +/- 1.27%, P \u3c 0.05). AUC was not improved by ARG treatment but was significantly improved above SED animals in both RUN and RUN + ARG-treated animals. Maximal relaxation was elevated above SED in RUN + ARG animals only. L-[H-3] arginine uptake was impaired in both SED and ARG animals and was improved in RUN and RUN + ARG animals. The results suggest that voluntary wheel running is an effective therapy to improve vascular function in CKD and may be more beneficial when combined with L-arginine

A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic.

BACKGROUND: The coronavirus pandemic (Covid-19) presents a variety of challenges for ongoing clinical trials, including an inevitably higher rate of missing outcome data, with new and non-standard reasons for missingness. International drug trial guidelines recommend trialists review plans for handling missing data in the conduct and statistical analysis, but clear recommendations are lacking. METHODS: We present a four-step strategy for handling missing outcome data in the analysis of randomised trials that are ongoing during a pandemic. We consider handling missing data arising due to (i) participant infection, (ii) treatment disruptions and (iii) loss to follow-up. We consider both settings where treatment effects for a 'pandemic-free world' and 'world including a pandemic' are of interest. RESULTS: In any trial, investigators should; (1) Clarify the treatment estimand of interest with respect to the occurrence of the pandemic; (2) Establish what data are missing for the chosen estimand; (3) Perform primary analysis under the most plausible missing data assumptions followed by; (4) Sensitivity analysis under alternative plausible assumptions. To obtain an estimate of the treatment effect in a 'pandemic-free world', participant data that are clinically affected by the pandemic (directly due to infection or indirectly via treatment disruptions) are not relevant and can be set to missing. For primary analysis, a missing-at-random assumption that conditions on all observed data that are expected to be associated with both the outcome and missingness may be most plausible. For the treatment effect in the 'world including a pandemic', all participant data is relevant and should be included in the analysis. For primary analysis, a missing-at-random assumption - potentially incorporating a pandemic time-period indicator and participant infection status - or a missing-not-at-random assumption with a poorer response may be most relevant, depending on the setting. In all scenarios, sensitivity analysis under credible missing-not-at-random assumptions should be used to evaluate the robustness of results. We highlight controlled multiple imputation as an accessible tool for conducting sensitivity analyses. CONCLUSIONS: Missing data problems will be exacerbated for trials active during the Covid-19 pandemic. This four-step strategy will facilitate clear thinking about the appropriate analysis for relevant questions of interest

A discursive psychology analysis of emotional support for men with colorectal cancer

Recent research into both masculinity and health, and the provision of social support for people with cancer has focussed upon the variations that may underlie broad assumptions about masculine health behaviour. The research reported here pursues this interest in variation by addressing the discursive properties of talk about emotional support, by men with colorectal cancer - an understudied group in the social support and cancer literature. Semi-structured interviews were conducted with eight men with colorectal cancer, and the transcripts analysed using an intensive discursive psychology approach. From this analysis two contrasting approaches to this group of men’s framing of emotional support in the context of cancer are described. First, talk about cancer was positioned as incompatible with preferred masculine identities. Second, social contact that affirms personal relationships was given value, subject to constraints arising from discourses concerning appropriate emotional expression. These results are discussed with reference to both the extant research literature on masculinity and health, and their clinical implications, particularly the advice on social support given to older male cancer patients, their families and friends

Analysis of Peer Intersection Data for Arterial Traffic Signal Coordination Decisions

This is the author-accepted manuscript version of Day, C.M., T.M. Brennan, H. Premachandra, J.R. Sturdevant, and D.M. Bullock, “Analysis of Peer Data on Intersections for Decisions About Coordination of Arterial Traffic Signal,”Transportation Research Record: Journal of the Transportation Research Board, No. 2259, Transportation Research Board of the National Academies, Washington, D.C., pp. 23–36, 2011, copyright National Academy of Sciences.http://dx.doi.org/10.3141/2259-03 Its corresponding poster can be found here:http://docs.lib.purdue.edu/atspmw/2016/Posters/3

“A slippery slope”: a scoping review of the self- injection of unlicensed oils and fillers as body enhancement.

Self-injection of a range of oils and fillers for body enhancement dates back to 1899, but due to significant associated harms and fatalities this practice has been largely linked to distinct cultural groups in recent times. This scoping review gathers what is currently known on the self injection of body fillers for aesthetic purposes, using Arksey and O’Malley’s (2005) five stage iterative process scoping review methodology. Thematic manual coding then organised the data into themes through identified patterns: indicative profiling of individuals who self inject body fillers; motivation for use across types of oil injection; sourcing routes and documented harms. It was found that the majority of people who inject body fillers are male and do so to grossly increase muscle size. Injection of oils and other materials in the male genitalia was also described, in addition to female self-injection in the breast, hand and leg areas for augmentation. A range of health consequences were reviewed. Recommendations are made for further research into this unique phenomenon, which although is relatively rare warrant future research attention considering the documented increase in DIY facial fillers and contemporary body image culture