638 research outputs found
Water use and yields of no-till managed dryland grasspea and yellow pea under different planting configurations
Grasspea (GP) (Lathyrus sativus) is a drought-tolerant legume that can be grown for forage and grain. It has potential value to be used as a nitrogen-fixing crop in dryland rotations with non-legume grain crops. However, the agronomy of GP for the Central Great Plains region have not been investigated. The objective of this research was to compare the grain and biomass yield, as well as N accumulation of GP relative to field pea (FP) in two planting configurations. We carried out a 3-year field experiment to compare dryland GP with Admiral yellow field pea (Pisum sativum) in two configurations: (1) a wide row spacing with lower population (WL) with 76-cm rows with 75 kg seeds planted per ha, and (2) a narrower row spacing with a higher population (NH) with 19-cm rows with 136 kg seeds planted per ha. We measured the biomass, grain yield, N content, and soil water use. Our results show that the NH treatment out-yielded the WL treatment in both pea species. The GP had higher yield than FP on the lowest yielding year, while FP yielded better when overall yields were higher. Biomass production was also higher for the NH configuration, and GP was a higher biomass producer than FP over the 3-year study. The GP had higher N concentration in shoots and seed compared to FP, indicating higher N-fixing capacity. The FP matured faster than GP, and had marginally higher grain water use efficiency than GP. Our results show that GP is a viable alternative legume for the Central Great Plains, with comparable yields in low precipitation years. However, the longer growing season required by GP to mature has water use implications in years with reduced water availability in mid to late summer
Microtubule cross-linking triggers the directional motility of kinesin-5
Although assembly of the mitotic spindle is known to be a precisely controlled process, regulation of the key motor proteins involved remains poorly understood. In eukaryotes, homotetrameric kinesin-5 motors are required for bipolar spindle formation. Eg5, the vertebrate kinesin-5, has two modes of motion: an adenosine triphosphate (ATP)–dependent directional mode and a diffusive mode that does not require ATP hydrolysis. We use single-molecule experiments to examine how the switching between these modes is controlled. We find that Eg5 diffuses along individual microtubules without detectable directional bias at close to physiological ionic strength. Eg5's motility becomes directional when bound between two microtubules. Such activation through binding cargo, which, for Eg5, is a second microtubule, is analogous to known mechanisms for other kinesins. In the spindle, this might allow Eg5 to diffuse on single microtubules without hydrolyzing ATP until the motor is activated by binding to another microtubule. This mechanism would increase energy and filament cross-linking efficiency
Baseline Thymopoietic Function and Post-Transplant Immune Recovery after Adult Cord Blood Transplantation
Efficient Bayesian calibration of aerodynamic wind turbine models using surrogate modeling
This paper presents an efficient strategy for the Bayesian calibration of parameters of aerodynamic wind turbine models. The strategy relies on constructing a surrogate model (based on adaptive polynomial chaos expansions), which is used to perform both parameter selection using global sensitivity analysis and parameter calibration with Bayesian inference. The effectiveness of this approach is shown in two test cases: calibration of airfoil polars based on the measurements from the DanAero MW experiments, and calibration of five yaw model parameters based on measurements on the New MEXICO turbine in yawed conditions. In both cases, the calibrated models yield results much closer to the measurement data, and in addition they are equipped with an estimate of the uncertainty in the predictions
Efficient Bayesian calibration of aerodynamic wind turbine models using surrogate modeling
This paper presents an efficient strategy for the Bayesian calibration of parameters of aerodynamic wind turbine models. The strategy relies on constructing a surrogate model (based on adaptive polynomial chaos expansions), which is used to perform both parameter selection using global sensitivity analysis and parameter calibration with Bayesian inference. The effectiveness of this approach is shown in two test cases: calibration of airfoil polars based on the measurements from the DANAERO MW experiments and calibration of five yaw model parameters based on measurements on the New MEXICO turbine in yawed conditions. In both cases, the calibrated models yield results much closer to the measurement data, and in addition they are equipped with an estimate of the uncertainty in the predictions
Cosmic microwave background anisotropy power spectrum statistics for high precision cosmology
As the era of high precision cosmology approaches, the empirically determined
power spectrum of the microwave background anisotropy, , will provide a
crucial test for cosmological theories. We present a unified semi-analytic
framework for the study of the statistical properties of the coefficients
computed from the results of balloon, ground based, and satellite experiments.
An illustrative application shows that commonly used approximations {\it bias}
the estimation of the baryon parameter at the 1% level even for a
satellite capturing as much as % of the sky.Comment: 4 pages, 3 figures. Also available at
http://www.tac.dk/~wandelt/downloads.htm
Aerostructural design optimization of a 100-passenger regional jet with surrogate-based mission analysis
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106481/1/AIAA2013-4372.pd
Monte Carlo Methods for Estimating Interfacial Free Energies and Line Tensions
Excess contributions to the free energy due to interfaces occur for many
problems encountered in the statistical physics of condensed matter when
coexistence between different phases is possible (e.g. wetting phenomena,
nucleation, crystal growth, etc.). This article reviews two methods to estimate
both interfacial free energies and line tensions by Monte Carlo simulations of
simple models, (e.g. the Ising model, a symmetrical binary Lennard-Jones fluid
exhibiting a miscibility gap, and a simple Lennard-Jones fluid). One method is
based on thermodynamic integration. This method is useful to study flat and
inclined interfaces for Ising lattices, allowing also the estimation of line
tensions of three-phase contact lines, when the interfaces meet walls (where
"surface fields" may act). A generalization to off-lattice systems is described
as well.
The second method is based on the sampling of the order parameter
distribution of the system throughout the two-phase coexistence region of the
model. Both the interface free energies of flat interfaces and of (spherical or
cylindrical) droplets (or bubbles) can be estimated, including also systems
with walls, where sphere-cap shaped wall-attached droplets occur. The
curvature-dependence of the interfacial free energy is discussed, and estimates
for the line tensions are compared to results from the thermodynamic
integration method. Basic limitations of all these methods are critically
discussed, and an outlook on other approaches is given
Burden of Rare Sarcomere Gene Variants in the Framingham and Jackson Heart Study Cohorts
Rare sarcomere protein variants cause dominant hypertrophic and dilated cardiomyopathies. To evaluate whether allelic variants in eight sarcomere genes are associated with cardiac morphology and function in the community, we sequenced 3,600 individuals from the Framingham Heart Study (FHS) and Jackson Heart Study (JHS) cohorts. Out of the total, 11.2% of individuals had one or more rare nonsynonymous sarcomere variants. The prevalence of likely pathogenic sarcomere variants was 0.6%, twice the previous estimates; however, only four of the 22 individuals had clinical manifestations of hypertrophic cardiomyopathy. Rare sarcomere variants were associated with an increased risk for adverse cardiovascular events (hazard ratio: 2.3) in the FHS cohort, suggesting that cardiovascular risk assessment in the general population can benefit from rare variant analysis
The state of the Martian climate
60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
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