8 research outputs found

    High Brain Tissue Oxygen Tension during Ventilation with 100% Oxygen after Fetal Asphyxia in Newborn Sheep.

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    The optimal FiO2 for newborn resuscitation is still not settled. We hypothesized that short-lasting oxygen ventilation after intrauterine asphyxia would not cause arterial or cerebral hyperoxia, and therefore be innocuous. The umbilical cord of fetal sheep was clamped and 10 min later, after delivery, ventilation with air (n=7) or with 100% oxygen for 3 (n=6) or 30 min (n=5), followed by air, was started. Among the eleven lambs given 100% O2, oxygen tension (PO2) was 10.7 (1.8 - 56) kPa [median (range)] in arterial samples taken after 2.5 min of ventilation. In those ventilated with 100% oxygen for 30 min, brain tissue PO2 (PbtO2) increased from less than 0.1 kPa in each lamb to individual maxima of 56 (30-61) kPa, while in those given oxygenfor just 3 min, PbtO2peaked at 4.2 (2.9 - 46) kPa. The maximal PbtO2 in air-ventilated lambs was 2.9 (0.8-5.4) kPa. Heart rate and blood pressure increased equally fast in the three groups. Thus, prolonged ventilation with 100% oxygen caused an increase in PbtO2of a magnitude previously only reported under hyperbaric conditions. Reducing the time of 100% oxygen ventilation to 3 min did not consistently avert systemic hyperoxia

    Open questions in astrophysically triggered gravitational wave searches

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    Sources of gravitational waves are often expected to also be observable through several other messengers, such as gamma rays, X-rays, optical, radio, and/or neutrino emission. Some of these channels are already being used in searches for gravitational waves with the LIGO-GEO600-Virgo interferometer network, and others are currently being incorporated into new searches. Astrophysical targets include gamma-ray bursts, soft-gamma repeaters, supernovae, and glitching pulsars. The simultaneous observation of electromagnetic or neutrino emission could be a crucial aspect for the first direct detection of gravitational waves. Information on the progenitor, such as trigger time, direction and expected frequency range, can enhance our ability to identify gravitational wave signatures with amplitudes close to the noise floor of the detector. Furthermore, combining gravitational waves with electromagnetic and neutrino observations will enable the extraction of scientific insight that was hidden from us before. The paper discusses the status of transient multimessenger detection efforts as well as intriguing questions that might be resolved in the future by advanced and third generation gravitational wave detector

    Search for gravitational waves from compact binary coalescence in LIGO and Virgo data from S5 and VSR1

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    We report the results of the first search for gravitational waves from compact binary coalescence using data from the LIGO and Virgo detectors. Five months of data were collected during the concurrent S5 (LIGO) and VSR1 (Virgo) science runs. The search focused on signals from binary mergers with a total mass between 2 and 35 Msun. No gravitational waves are identified. The cumulative 90%-confidence upper limits on the rate of compact binary coalescence are calculated for non-spinning binary neutron stars, black hole-neutron star systems, and binary black holes to be 8.7x10^-3, 2.2x10^-3 and 4.4x10^-4 yr^-1 L_10^-1 respectively, where L_10 is 10^10 times the blue solar luminosity. These upper limits are compared with astrophysical expectations

    Observation of the exclusive reaction e(+)e(-)->phi eta at root s=10.58 GeV

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    We report the observation of e(+)e(-)->phi eta near root s=10.58 GeV with 6.5 sigma significance in the K+K-gamma gamma final state in a data sample of 224 fb(-1) collected by the BABAR experiment at the PEP-II e(+)e(-) storage rings. We measure the restricted radiation-corrected cross section to be sigma(e(+)e(-)->phi eta)=2.1 +/- 0.4(stat)+/- 0.1(syst) fb within the range vertical bar cos theta(*)vertical bar < 0.8, where theta(*) is the center-of-mass polar angle of the phi meson. The phi meson is required to be in the invariant mass range of 1.008 < m(phi)< 1.035 GeV/c(2). The radiation-corrected cross section in the full cos theta(*) range is extrapolated to be 2.9 +/- 0.5(stat)+/- 0.1(syst) fb

    Observation of a new D-s meson decaying to DK at a mass of 2.86 GeV/c(2) RID C-2728-2008 RID C-5223-2009 RID C-5719-2008 RID D-1055-2009 RID A-2675-2009

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    We observe a new D-s meson with mass (2856.6 +/- 1.5(stat)+/- 5.0(syst)) MeV/c(2) and width (48 +/- 7(stat)+/- 10(syst)) MeV/c(2) decaying into (DK+)-K-0 and (D+KS0). In the same mass distributions, we also observe a broad structure with mass (2688 +/- 4(stat)+/- 3(syst)) MeV/c(2) and width (112 +/- 7(stat)+/- 36(syst)) MeV/c(2). To obtain this result, we use 240 fb(-1) of data recorded by the BABAR detector at the PEP-II asymmetric-energy e(+)e(-) storage rings at the Stanford Linear Accelerator Center running at center-of-mass energies near 10.6 GeV

    Study of resonances in exclusive B decays to (D)over-bar((*))D((*))K

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    We present a study of resonances in exclusive decays of B mesons to (D) over bar (DK)-D-(*)-K-(*). We report the observation of the decays B ->(D) over bar D-(*)(s1)+(2536) where the D-s1(+)(2536) is reconstructed in the (DK+)-K-*0 and (D*+KS0) decay channels. We report also the observation of the decays B ->psi(3770)K where the psi(3770) decays to (D) over bar D-0(0) and D-D+. In addition, we present the observation of an enhancement for the (D) over bar D-*0(0) invariant mass in the decays B ->(D) over bar (DK)-D-*0-K-0, at a mass of (3875.1(-0.5)(+0.7)+/- 0.5) MeV/c(2) with a width of (3.0(-1.4)(+1.9)+/- 0.9) MeV (the first errors are statistical and the second are systematic). Branching fractions and spin studies are shown for the three resonances. The results are based on 347 fb(-1) of data collected with the BABAR detector at the PEP-II B factory
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