117 research outputs found
Skills for Learning Network of High School Students in Galicia
El objetivo del presente trabajo radica en identificar las necesidades formativas para el trabajo en red de
los alumnos de secundaria de Galicia. Se presenta un análisis exploratorio de sus niveles de competencia
en esta materia valorados autopercibidos por los propios alumnos y percibidos por sus profesores. Los
resultados muestran niveles de preparación superiores en competencias instrumentales, e insuficientes en
otras mas directamente relacionadas con el aprendizaje autónomo y orientado a la creación de
conocimiento, sugiriendo la necesidad de propuestas de formación que mejoren la explotación y el uso de
las TIC para la optimización de los procesos de aprendizaje.The aim of the present study is to identify the training needs for educational network of secondary
education students in Galicia. An exploratory analysis of the competence levels in educational network
assessed by the own students and by their teachers. The results show higher levels in instrumental
competences, and insufficient in those competences related to autonomous learning and knowledge
development. Therefore, these data suggest the need of curricular and systematic training to improve the
exploitation and management of the ICT in order to optimize the learning process
Competences for dealing with cyberbullying in secondary schools: an approach to the needs of school principals and teachers
El ciberacoso es un fenómeno con una alta prevalencia en la Educación Secundaria Obligatoria. Esta situación implica un nuevo desafío para los centros educativos, especialmente, para directores y docentes. Este trabajo presenta la percepción que directores/as y profesorado de centros educativos de Educación Secundaria de Galicia tienen con relación al ciberacoso, su competencia para afrontarlo y sus propuestas de actuación para facilitar la intervención ante este fenómeno. La muestra estuvo compuesta por un total de 314 directores y docentes. Se usan análisis descriptivos para describir la muestra y las variables analizadas, un análisis de componentes principales para comprobar las propiedades psicométricas de la escala utilizada y análisis no paramétricos para contrastes estadísticos. Los participantes informan de una baja percepción del ciberacoso en los centros educativos. Los docentes profesores con cargos de gestión académica (directores, y jefes de estudio) así como los orientadores, consideran que son más competentes que los docentes para abordar o gestionar situaciones de ciberacoso. Desarrollar políticas contra el ciberacoso y utilizar días para formar al profesorado en ciberacoso a través de actividades organizadas por el equipo de orientación es fundamentalCyberbullying is a phenomenon with a high prevalence in secondary school. This situation implies a new challenge for schools, especially for head teachers and teachers. This paper presents the perception of school principals and teachers at secondary schools in Galicia in relation to cyberbullying, their competence to deal with it and their proposals for action to facilitate intervention against this phenomenon. The sample consisted of a total of 314 school principals and teachers. Descriptive analyses are used to describe the sample and the variables analyzed, a principal components analysis to test the psychometric properties of the scale used and non-parametric analyses for statistical contrasts. Participants report a low perception of cyberbullying in schools. Teachers in academic management positions (principals, and heads of studies) as well as guidance counsellors consider themselves more competent than teachers to deal with or manage cyberbullying situations. Developing anti-cyberbullying policies and using days to train teachers on cyberbullying through activities organized by the guidance team is essentialS
Neurons of the Dentate Molecular Layer in the Rabbit Hippocampus
The molecular layer of the dentate gyrus appears as the main entrance gate for information into the hippocampus, i.e., where the perforant path axons from the entorhinal cortex synapse onto the spines and dendrites of granule cells. A few dispersed neuronal somata appear intermingled in between and probably control the flow of information in this area. In rabbits, the number of neurons in the molecular layer increases in the first week of postnatal life and then stabilizes to appear permanent and heterogeneous over the individuals’ life span, including old animals. By means of Golgi impregnations, NADPH histochemistry, immunocytochemical stainings and intracellular labelings (lucifer yellow and biocytin injections), eight neuronal morphological types have been detected in the molecular layer of developing adult and old rabbits. Six of them appear as interneurons displaying smooth dendrites and GABA immunoreactivity: those here called as globoid, vertical, small horizontal, large horizontal, inverted pyramidal and polymorphic. Additionally there are two GABA negative types: the sarmentous and ectopic granular neurons. The distribution of the somata and dendritic trees of these neurons shows preferences for a definite sublayer of the molecular layer: small horizontal, sarmentous and inverted pyramidal neurons are preferably found in the outer third of the molecular layer; vertical, globoid and polymorph neurons locate the intermediate third, while large horizontal and ectopic granular neurons occupy the inner third or the juxtagranular molecular layer. Our results reveal substantial differences in the morphology and electrophysiological behaviour between each neuronal archetype in the dentate molecular layer, allowing us to propose a new classification for this neural population
A method for automatically extracting infectious disease-related primers and probes from the literature
Interrelación de laboratorios de control y laboratorios de investigación en España para la armonización de metodologías de determinación de toxinas paralizantes
XII Congreso Nacional de Agricultura, Madrid 24-26 de noviembre de 2009Marketing of cultured and harvested shellfish is linked to monitoring programs for granting food safety. Its complexity requires constant cooperation between research and monitoring laboratories in order to improve sampling and analysing performances, achieve legal requirements, etc. for increasing consumer’s health protection but not reducing producer’s benefits. The JACUMAR project «Comparison of methodologies for the evaluation of Paralytic Shellfish Poisoning (PSP) toxins in bivalves. Application for aquaculture in Spain» groups research and monitoring laboratories from Galicia, Andalucía and Cataluña. Efforts are focused on detection and quantification of PSP toxins, searching an analytical method able to fulfil technical and management requirementsEste proyecto está financiado por la Junta Asesora de Cultivos Marinos (JACUMAR), y los programas de control por los gobiernos autónomos de Galicia, Andalucía y CataluñaN
Evaluation of the relationship between effervescent paracetamol and blood pressure: clinical trial
Dietary animal and plant protein intakes and their associations with obesity and cardio-metabolic indicators in European adolescents: The HELENA cross-sectional study
Background: Previous studies suggest that dietary protein might play a beneficial role in combating obesity and its related chronic diseases. Total, animal and plant protein intakes and their associations with anthropometry and serum biomarkers in European adolescents using one standardised methodology across European countries are not well documented. Objectives: To evaluate total, animal and plant protein intakes in European adolescents stratified by gender and age, and to investigate their associations with cardio-metabolic indicators (anthropometry and biomarkers). Methods: The current analysis included 1804 randomly selected adolescents participating in the HELENA study (conducted in 2006-2007) aged 12.5-17.5 y (47% males) who completed two non-consecutive computerised 24-h dietary recalls. Associations between animal and plant protein intakes, and anthropometry and serum biomarkers were examined with General linear Model multivariate analysis. Results: Average total protein intake exceeded the recommendations of World Health Organization and European Food Safety Authority. Mean total protein intake was 96 g/d (59% derived from animal protein). Total, animal and plant protein intakes (g/d) were significantly lower in females than in males and total and plant protein intakes were lower in younger participants (12.5-14.9 y). Protein intake was significantly lower in underweight subjects and higher in obese ones; the direction of the relationship was reversed after adjustments for body weight (g/(kg.d)). The inverse association of plant protein intakes was stronger with BMI z-score and body fat percentage (BF%) compared to animal protein intakes. Additionally, BMI and BF% were positively associated with energy percentage of animal protein. Conclusions: This sample of European adolescents appeared to have adequate total protein intake. Our findings suggest that plant protein intakes may play a role in preventing obesity among European adolescents. Further longitudinal studies are needed to investigate the potential beneficial effects observed in this study in the prevention of obesity and related chronic diseases
Evaluation of iron status in European adolescents through biochemical iron indicators: the HELENA Study
BACKGROUND/OBJECTIVES: To assess the iron status among European adolescents through selected biochemical parameters in a cross-sectional study performed in 10 European cities. SUBJECTS/METHODS: Iron status was defined utilising biochemical indicators. Iron depletion was defined as low serum ferritin (SF8.5 mg/l) plus iron depletion. Iron deficiency anaemia (IDA) was defined as ID with haemoglobin (Hb) below the WHO cutoff for age and sex: 12.0 g/dl for girls and for boys aged 12.5-14.99 years and 13.0 g/dl for boys aged ≥15 years. Enzyme linked immunosorbent assay was used as analytical method for SF, sTfR and C-reactive protein (CRP). Subjects with indication of inflammation (CRP >5 mg/l) were excluded from the analyses. A total of 940 adolescents aged 12.5-17.49 years (438 boys and 502 girls) were involved. RESULTS: The percentage of iron depletion was 17.6%, significantly higher in girls (21.0%) compared with boys (13.8%). The overall percentage of ID and IDA was 4.7 and 1.3%, respectively, with no significant differences between boys and girls. A correlation was observed between log (SF) and Hb (r = 0.36, P < 0.01), and between log (sTfR) and mean corpuscular haemoglobin (r = -0.30, P < 0.01). Iron body stores were estimated on the basis of log (sTfR/SF). A higher percentage of negative values of body iron was recorded in girls (16.5%) with respect to boys (8.3%), and body iron values tended to increase with age in boys, whereas the values remained stable in girls. CONCLUSIONS: To ensure adequate iron stores, specific attention should be given to girls at European level to ensure that their dietary intake of iron is adequate.status: publishe
RICORS2040 : The need for collaborative research in chronic kidney disease
Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true
CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3
ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain.MethodsIn total, 71 hospitals, representing all 50 Spanish provinces, collected the first 10 isolates per hospital (February to May 2019); CPE isolates were first identified according to EUCAST (meropenem MIC > 0.12 mg/L with immunochromatography, colorimetric tests, carbapenem inactivation, or carbapenem hydrolysis with MALDI-TOF). Prevalence and incidence were calculated according to population denominators. Antibiotic susceptibility testing was performed using the microdilution method (EUCAST). All 403 isolates collected were sequenced for high-resolution single-nucleotide polymorphism (SNP) typing, core genome multilocus sequence typing (cgMLST), and resistome analysis.ResultsIn total, 377 (93.5%) CP-Kpn and 26 (6.5%) CP-Eco isolates were collected from 62 (87.3%) hospitals in 46 (92%) provinces. CP-Kpn was more prevalent in the blood (5.8%, 50/853) than in the urine (1.4%, 201/14,464). The cumulative incidence for both CP-Kpn and CP-Eco was 0.05 per 100 admitted patients. The main carbapenemase genes identified in CP-Kpn were blaOXA–48 (263/377), blaKPC–3 (62/377), blaVIM–1 (28/377), and blaNDM–1 (12/377). All isolates were susceptible to at least two antibiotics. Interregional dissemination of eight high-risk CP-Kpn clones was detected, mainly ST307/OXA-48 (16.4%), ST11/OXA-48 (16.4%), and ST512-ST258/KPC (13.8%). ST512/KPC and ST15/OXA-48 were the most frequent bacteremia-causative clones. The average number of acquired resistance genes was higher in CP-Kpn (7.9) than in CP-Eco (5.5).ConclusionThis study serves as a first step toward WGS integration in the surveillance of carbapenemase-producing Enterobacterales in Spain. We detected important epidemiological changes, including increased CP-Kpn and CP-Eco prevalence and incidence compared to previous studies, wide interregional dissemination, and increased dissemination of high-risk clones, such as ST307/OXA-48 and ST512/KPC-3
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