41 research outputs found
Libration driven elliptical instability
The elliptical instability is a generic instability which takes place in any
rotating flow whose streamlines are elliptically deformed. Up to now, it has
been widely studied in the case of a constant, non-zero differential rotation
between the fluid and the elliptical distortion with applications in
turbulence, aeronautics, planetology and astrophysics. In this letter, we
extend previous analytical studies and report the first numerical and
experimental evidence that elliptical instability can also be driven by
libration, i.e. periodic oscillations of the differential rotation between the
fluid and the elliptical distortion, with a zero mean value. Our results
suggest that intermittent, space-filling turbulence due to this instability can
exist in the liquid cores and sub-surface oceans of so-called synchronized
planets and moons
Experimental study of libration-driven zonal flows in non-axisymmetric containers
International audienceOrbital dynamics that lead to longitudinal libration of celestial bodies also result in an elliptically deformed equatorial core-mantle boundary. The non-axisymmetry of the boundary leads to a topographic coupling between the assumed rigidmantle and the underlying low viscosity fluid.The present experimental study investigates theeffect of non axisymmetric boundaries on the zonal flow driven by longitudinal libration. For large enough equatorial ellipticity, we report intermittent space-filling turbulence in particular bands of resonant frequency correlated with larger amplitude zonal flow. The mechanism underlying the intermittent turbulence has yet to be unambiguously determined. Nevertheless, recent numerical simulations in triaxial and biaxial ellipsoids suggest that it may be associated with the growth and collapse of an elliptical instability (Cebron et al., 2012). Outside of the band of resonance, we find that the background flow is laminar and the zonal flow becomes independent of the geometry at first order, in agreement with a non linear mechanism in the Ekman boundary layer (e.g. Calkins et al.; 2010, Sauret and Le Dizes, 2012b)
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis
Background
A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous. To bridge this gap in knowledge, we synthesized the existing epidemiologic evidence on the relation between occupational exposure to benzene and the risk of leukemia, including all types combined and the four main subgroups acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML).
Methods
A systematic literature review was carried out using two databases 'Medline' and 'Embase' from 1950 through to July 2009. We selected articles which provided information that can be used to estimate the relation between benzene exposure and cancer risk (effect size).
Results
In total 15 studies were identified in the search, providing 16 effect estimates for the main analysis. The summary effect size for any leukemia from the fixed-effects model was 1.40 (95% CI, 1.23-1.57), but the study-specific estimates were strongly heterogeneous (I2 = 56.5%, Q stat = 34.47, p = 0.003). The random-effects model yielded a summary- effect size estimate of 1.72 (95% CI, 1.37-2.17). Effect estimates from 9 studies were based on cumulative exposures. In these studies the risk of leukemia increased with a dose-response pattern with a summary-effect estimate of 1.64 (95% CI, 1.13-2.39) for low (< 40 ppm-years), 1.90 (95% CI, 1.26-2.89) for medium (40-99.9 ppm-years), and 2.62 (95% CI, 1.57-4.39) for high exposure category (> 100 ppm-years). In a meta-regression, the trend was statistically significant (P = 0.015). Use of cumulative exposure eliminated heterogeneity. The risk of AML also increased from low (1.94, 95% CI, 0.95-3.95), medium (2.32, 95% CI, 0.91-5.94) to high exposure category (3.20, 95% CI, 1.09-9.45), but the trend was not statistically significant.
Conclusions
Our study provides consistent evidence that exposure to benzene at work increases the risk of leukemia with a dose-response pattern. There was some evidence of an increased risk of AML and CLL. The meta-analysis indicated a lack of association between benzene exposure and the risk of CML
Carbon-cryogel hierarchical composites as effective and scalable filters for removal of trace organic pollutants from water
Effective technologies are required to remove organic micropollutants from large fluid volumes to overcome present and future challenges in water and effluent treatment. A novel hierarchical composite filter material for rapid and effective removal of polar organic contaminants from water was developed. The composite is fabricated from phenolic resin-derived carbon microbeads with controllable porous structure and specific surface area embedded in a monolithic, flow permeable, poly(vinyl alcohol) cryogel. The bead-embedded monolithic composite filter retains the bulk of the high adsorptive capacity of the carbon microbeads while improving pore diffusion rates of organic pollutants. Water spiked with organic contaminants, both at environmentally relevant concentrations and at high levels of contamination, was used to determine the purification limits of the filter. Flow through tests using water spiked with the pesticides atrazine (32 mg/L) and malathion (16 mg/L) indicated maximum adsorptive capacities of 641 and 591 mg pollutant/g carbon, respectively. Over 400 bed volumes of water contaminated with 32 mg atrazine/L, and over 27,400 bed volumes of water contaminated with 2 μg atrazine/L, were treated before pesticide guideline values of 0.1 μg/L were exceeded. High adsorptive capacity was maintained when using water with high total organic carbon (TOC) levels and high salinity. The toxicity of water filtrates was tested in vitro with human epithelial cells with no evidence of cytotoxicity after initial washing
Supramolecular recognition of estrogens via molecularly imprinted polymers
The isolation and preconcentration of estrogens from new types of biological samples (acellular and protein-free simulated body fluid) by molecularly imprinted solid-phase extraction has been described. In this technique, supramolecular receptors, namely molecularly imprinted polymers (MIPs) are used as a sorbent material. The recognition sites of MIPs were prepared by non-covalent multiple interactions and formed with the target 17β-estradiol as a template molecule. High-performance liquid chromatography with spectroscopic UV, selective, and a sensitive electrochemical CoulArray detector was used for the determination of 17β-estradiol, estrone, and estriol in simulated body fluid which mimicked human plasma
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Libration driven elliptical instability
The elliptical instability is a generic instability which takes place in any rotating flow whose streamlines are elliptically deformed. Up to now, it has been widely studied in the case of a constant, non-zero differential rotation between the fluid and the elliptical distortion with applications in turbulence, aeronautics, planetology, and astrophysics. In this letter, we extend previous analytical studies and report the first numerical and experimental evidence that elliptical instability can also be driven by libration, i.e., periodic oscillations of the differential rotation between the fluid and the elliptical distortion, with a zero mean value. Our results suggest that intermittent, space-filling turbulence due to this instability can exist in the liquid cores and subsurface oceans of so-called synchronized planets and moons. © 2012 American Institute of Physics
Libration driven elliptical instability (vol 24, 061703, 2012)
International audienc