Correction:Lipid nanoparticle-based formulations for high-performance dentistry applications

The authors regret that an error appears in the timeline of Fig. 1a. The corrected version of Fig. 1 is provided below. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers. (Figure Presented).</p

A note on comonotonicity and positivity of the control components of decoupled quadratic FBSDE

In this small note we are concerned with the solution of Forward-Backward Stochastic Differential Equations (FBSDE) with drivers that grow quadratically in the control component (quadratic growth FBSDE or qgFBSDE). The main theorem is a comparison result that allows comparing componentwise the signs of the control processes of two different qgFBSDE. As a byproduct one obtains conditions that allow establishing the positivity of the control process.Comment: accepted for publicatio

Post-implementation Review of the Himalaya Home Care Project for Home Isolated COVID-19 Patients in Nepal

Background: The emergence of coronavirus disease 2019 (COVID-19) has resulted in a pandemic that has significantly impacted healthcare systems at a global level. Health care facilities in Nepal, as in other low- and middle-income countries, have limited resources for the treatment and management of COVID-19 patients. Only critical cases are admitted to the hospital resulting in most patients in home isolation. Methods: Himalaya Home Care (HHC) was initiated to monitor and provide counseling to home isolated COVID-19 patients for disease prevention, control, and treatment. Counselors included one physician and four nurses. Lists of patients were obtained from district and municipal health facilities. HHC counselors called patients to provide basic counseling services. A follow-up check-in phone call was conducted 10 days later. During this second call, patients were asked about their perceptions of the HHC program. Project objects were: (1) To support treatment of home isolated persons with mild to moderate COVID-19, decrease burden of hospitalizations, and decrease risks for disease transmission; and, (2) To improve the health status of marginalized, remote, and vulnerable populations in Nepal during the COVID-19 pandemic. Results: Data from 5823 and 3988 patients from May 2021-February 2022 were entered in initial and follow-up forms on a REDCap database. The majority of patients who received counseling were satisfied. At follow-up, 98.4% of respondents reported that HHC prevented hospitalization, 76.5% reported they could manage their symptoms at home, and 69.5% reported that counseling helped to limit the spread of COVID-19 in their household. Conclusions: Telehealth can be an essential strategy for providing services while keeping patients and health providers safe during the COVID-19 pandemic

Skills Mismatch in the Labour Market: An Agent-Based Modelling Approach

This research analyses the skills mismatch dynamics in the labour market using an agent-based model which is grounded in economic theory. The findings show the persistence of skills mismatch due to cyclical and structural factors in the economy. The output analyses highlight the sensitivity of skills mismatch to the initial endowment or characteristics of skill demand and supply in the region. This result is further supported by assessing policy response of skills mismatch. Training and investment policies are studied and the findings suggest that if a policy suitable to the region is implemented it can result in a reduction of skills mismatch and an increase in social welfare of the economy. Sectoral analysis of skills mismatch for Essex care sector finds issues such as failure of wage adjustment and ability of wages to signal shortages causes the persistence of skills mismatch in the sector. The research further analyses the impact of peer effect on skills mismatch to find that peer effect does affect the matching process by changing the supply of skills in the economy. Causal effects of exogenous frictions are thus found to impact the job search process. Analysis of spatial frictions in a single region and two-region setting is also conducted. The key findings from the regional analysis suggest that a high growth neighbouring area can decrease total skills mismatch of the system and of the local labour market but it comes at the cost of migration of high skilled workers to the neighbouring region leaving the local area pre-dominantly low skilled. Spatial frictions measured by commuting cost does not significantly impact these dynamics. The importance of regional and sectoral disaggregation while assessing skills mismatch and the measure of skills mismatch are recognized as the key considerations while designing policies aimed at addressing the labour market skills mismatch