Conjunto de actividades físicas y acciones educativas para personas adultas obesas de edades comprendidas entre 50 y 55 años, pertenecientes al Consejo Popular no.1 del municipio Guane

Con el objetivo de proponer un conjunto de actividades físicas y acciones educativas encaminadas a que las personas obesas de edades comprendidas entre 50 y 55 años pertenecientes al consejo popular #1 del municipio Guane logren un mejor nivel de enfrentamiento sobre la obesidad, las que como elementos fundamentales después de un diagnóstico poseen un índice de masa corporal (peso expresado para talla) por encima de 30 kg/m² en una muestra de 15 personas del grupo etario antes mencionado para un 41,7 % de 36 obesos que conformaban la unidad de análisis, es así que, a largo plazo en los resultados esperados de nuestro trabajo y que consideramos estén centrados en la combinación de tratamiento no farmacológico basados en el ejercicio físico en combinación conjunta en la educación de sus patrones alimentarios estos producirán cambios significativos en el peso corporal además de crear las condiciones necesarias para influir en la formación de estilos de vida sanos y lograr que la población se incorpore a las transformaciones del medio social que los rodea y de esta forma se modifican ellos mismos e incorporan valores y conductas de vida mucho más sanas que harán posible los cambios futuros que se esperan en el país dentro del campo de la salud asumiendo que el abordaje terapéutico de la obesidad por su naturaleza multifactorial debe ser objeto de múltiples sectores o miembros de la sociedad y en correspondencia con la realidad toda la comunidad una sus esfuerzos con vistas a evitar el incremento progresivo de esta enfermeda

Ten years in the dump: An updated review of the Miocene primate-bearing localities from Abocador de Can Mata (NE Iberian Peninsula)

More than ten years of paleontological fieldwork during the enlargement of the Can Mata Landfill (Abocador de Can Mata [ACM]), in els Hostalets de Pierola (Vallès-Penedès Basin, NE Iberian Peninsula) led to the recovery of >60,000 Miocene vertebrate remains. The huge sampling effort (due to continuous surveillance of heavy machinery digging activity, coupled with manual excavation and screen-washing of sediments) enabled generally rare faunal elements such as pliopithecoid and hominoid primates to be found. Thanks to detailed litho-, bio- and magnetostratigraphic controls, accurate dating is possible for all the recovered primate remains from 19 of the 235 localities defined along the 234 m-thick composite stratigraphic sequence of the ACM. Here we report updated estimated (interpolated) ages for these paleontological localities and review the timing of the primate succession in this area. Our results indicate that the whole ACM sequence is late Aragonian in age (MN6 and MN7+8) and includes seven magnetozones that are correlated to subchrons C5Ar.1r to C5r.2r (ca. 12.6 to 11.4 Ma). Great apes (dryopithecines) are first recorded at 12.4-12.3 Ma, but most of the finds (Anoiapithecus, Pierolapithecus and Dryopithecus) cluster between 12.0 and 11.9 Ma, followed by some indeterminate dryopithecine remains between 11.7 and 11.6 Ma. Pliopithecoids first appear at 12.1 Ma, being subsequently represented by Pliopithecus between 11.9 and 11.7 Ma. The small-bodied hominoid Pliobates is the youngest ACM primate, with an estimated age of 11.6 Ma. Although these primates probably overlapped in time, their co-occurrence is recorded only twice, at 11.9 Ma (a dryopithecine with Pliopithecus) and at 11.6 Ma (a dryopithecine with Pliobates). The rare co-occurrence between great apes and small-bodied catarrhines might be attributable to sampling biases and/or to presumed diverging ecological preferences of these groups. In the future, more detailed analyses of the fauna recovered from the long and densely-sampled ACM sequence will hopefully throw new light on this long-standing, unresolved question

Instrumento para la evaluación del climaterio y la menopausia en el primer nivel de atención: Instrument for the evaluation of climacteric and menopause in the first level of care

Introduction:The middle-aged female population will increase in the coming years and will require more medical care to relieve climacteric symptoms Objective: To validate an instrument for evaluating climacteric and menopause in primary care Methods: Prospective, cross-sectional, instrument-validation study. The sample was composed of women attending primary care centers. Our research consisted of three stages: initial review (literature review, translation), validation (content validity, pilot study) and psychometric properties (internal consistency and confirmatory factorial analysis). We analyzed the data using SPSS version 20. Results: 136 patients participated, with an average age of 48,6 years ± 5,3 and an average body mass index of 27,8 kg/m2 ± 4,4. In the first stage, we identified the most relevant symptoms: menstrual irregularities, hot flashes, vaginal problems, urinary incontinence, quality of sleep, and mood issues. The instrument was then translated by four professionals. For the second stage, we assessed content validity by expert judgment, obtaining an internal consistency of 0,77 and an initial reliability of 0,79. In the third stage, internal consistency was 0,69 and confirmatory factorial analysis was 0,7. The instrument consists of six questions; obtaining four or more positive answers warrants specialized care. Conclusion: We present a short instrument with adequate content validity and internal consistency, useful for managing climacteric symptoms at the primary care level.Introducción: La población de mujeres de mediana edad se incrementará en los próximos años y requerirá una mayor atención para aliviar los síntomas relacionados de atención con el climaterio. Objetivo: Validar un instrumento para la evaluación del climaterio y la menopausia en el primer nivel de atención. Métodos: Diseño de validación de instrumento, prospectivo y de corte transversal. Participaron mujeres que fueron atendidas en establecimientos de salud del primer nivel de atención. La investigación se realizó en tres fases, revisión inicial (revisión de literatura, traducción), ensayo (validez de contenido, prueba piloto) y propiedades psicométricas (análisis de consistencia interna, análisis factorial exploratorio). Para el análisis de datos se utilizó el programa SPSS versión 20. Resultados: Participaron 136 pacientes con una edad promedio de 48,6 años ± 5,3 y un promedio de índice de masa corporal 27,8 ± 4,4. En la primera fase se identificaron los síntomas más relevantes, irregularidades menstruales, sofocos, problemas vaginales, incontinencia urinaria, calidad de sueño y estado de ánimo. Se procedió a la traducción con la participación de cuatro profesionales. La segunda fase, de validez del contenido, fue mediante juicio de expertos, obteniendo una concordancia de 0,77 y una confiabilidad inicial 0,79. En la tercera fase, la consistencia interna fue 0,69 y 0,70 para análisis factorial exploratorio. El instrumento contiene seis preguntas, la obtención de ≥ 4 respuestas afirmativas justifican un manejo especializado. Conclusión: El instrumento es breve, tiene una adecuada validez de contenido y consistencia interna, útil para el manejo del climaterio en el primer nivel de atención

ERS International Congress, Madrid, 2019: highlights from the Sleep and Clinical Physiology Assembly

The 2019 European Respiratory Society (ERS) International Congress took place in Madrid, Spain, and served as a platform to find out the latest advances in respiratory diseases research. The research aims are to understand the physiology and consequences of those diseases, as well as the improvement in their diagnoses, treatments and patient care. In particular, the scientific sessions arranged by ERS Assembly 4 provided novel insights into sleep-disordered breathing and new knowledge in respiratory physiology. This article, divided by session, will summarise the most relevant studies presented at the ERS International Congress. Each section has been written by Early Career Members specialising in the different fields of this interdisciplinary assembly

Use of collective expertise as a tool to reinforce food safety management in Africa

The Erasmus+ project (2017-2020) entitled Societal Challenges and Governance of African Universities: the case of ALIments in Morocco, the Democratic Republic of the Congo and Senegal (DAfrAli) seeks to strengthen the governance capacity of African Higher Education Institutions to mobilize their resources in order to respond to major societal challenges in relation to external stakeholders. A work package consisted of organizing three workshops to use Collective Expertise as a tool for the identification of societal risks, in the area of food safety. These three workshops were conducted in Morocco, in Senegal and in Democratic Republic of Congo. The exercise was performed by country academics with the contribution of the European project partners. Collective Expertise gave results that demonstrated that, with a careful and diversified selection of experts, this methodology can have a deep importance to list the food hazards in a country. The results obtained can induce changes in university curricula, showed the social impacts of food safety, unveiled research needs and training needs for different agents in the food sector and above all the impact in food policy in a country. The collective expertise approach of the determination of hazards also permitted to discuss possible organization models for food risk management in the 3 countries

An updated biostratigraphy for the late Aragonian and the Vallesian of the Vallès-Penedès Basin (Catalonia)

The Vallès-Penedès Basin (Catalonia, Spain) is a classical area for the study of the Miocene land mammal faunas and includes one of the densest and most continuous records in Eurasia. Furthermore, it is the type area for the Vallesian European land mammal age. After decades of study a huge amount of bio- and magnetostratigraphic data have been collected, allowing an unprecedented dating accuracy. Here we provide an updated local biostratigraphy for the late Aragonian, Vallesian and Turolian of the Vallès-Penedès Basin. This new biostratigraphic scheme is almost exclusively based on fossil rodents, which are the most abundant and one of the best known mammal orders in the area. Our proposal represents a significant refinement compared to previous attempts and provides a formal diagnosis and description of each zone, as well as clear definition of boundaries and a reference locality and section. The chronology of zone boundaries and main bioevents is based on detailed magnetostratigraphic data. The defined biozones allow for the correlation of the sites without associated magnetostratigraphical data. Finally, the correlation of the Vallès-Penedès local zones with other detailed local biostratigraphies, such as those of the Calatayud-Montalbán and Teruel basins (east-central Spain) is discussed. The sequence and chronology of the main bioevents is roughly comparable, although the rodent succession and the structure of the assemblage show important differences between these areas

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes.

With defined culture protocol, human embryonic stem cells (hESCs) are able to generate cardiomyocytes in vitro, therefore providing a great model for human heart development, and holding great potential for cardiac disease therapies. In this study, we successfully generated a highly pure population of human cardiomyocytes (hCMs) (>95% cTnT(+)) from hESC line, which enabled us to identify and characterize an hCM-specific signature, at both the gene expression and DNA methylation levels. Gene functional association network and gene-disease network analyses of these hCM-enriched genes provide new insights into the mechanisms of hCM transcriptional regulation, and stand as an informative and rich resource for investigating cardiac gene functions and disease mechanisms. Moreover, we show that cardiac-structural genes and cardiac-transcription factors have distinct epigenetic mechanisms to regulate their gene expression, providing a better understanding of how the epigenetic machinery coordinates to regulate gene expression in different cell types

Bio- and magnetostratigraphic correlation of the Miocene primate bearing site of Castell de Barber a to the earliest Vallesian

Castell de Barberà, located in the Vallès-Penedès Basin (NE Iberian Peninsula), is one of the few European sites where pliopithecoids (Barberapithecus) and hominoids (cf. Dryopithecus) co-occur. The dating of this Miocene site has proven controversial. A latest Aragonian (MN7+8, ca. 11.88-11.18 Ma) age was long accepted by most authors, despite subsequent reports of hipparionin remains that signaled a Vallesian age. On the latter basis, Castell de Barberà was recently correlated to the early Vallesian (MN9, ca. 11.18-10.3 Ma) on tentative grounds. Uncertainties about the provenance of the Hippotherium material and the lack of magnetostratigraphic data precluded more accurate dating. After decades of inactivity, fieldwork was resumed in 2014-2015 at Castell de Barberà, including the original layer (CB-D) that in the past delivered most of the fossils. Here we report magnetostratigraphic results for the original outcrop and another nearby section. Our results indicate that CB-D is located in a normal polarity magnetozone at about midheight of a short (~20 m-thick) stratigraphic section. The composite magnetostratigraphic section (~50 m) has as many as four to six magnetozones. These multiple reversals, coupled with the in situ recovery of a Hippotherium humerus from CB-D in 2015, make it very unlikely the correlation of any of the sampled normal polarity magnetozones with the long normal polarity subchron C5n.2n (11.056-9.984 Ma), which is characteristic of the early Vallesian. Our results support instead a correlation of CB-D with C5r.1n (11.188-11.146 Ma), where the Aragonian/Vallesian boundary is situated, and therefore indicate an earliest Vallesian age of ~11.2 Ma for Castell de Barberà. Our results settle the longstanding debate about the Aragonian vs. Vallesian age of this site, which appears roughly coeval with the Creu de Conill 20 locality (11.18 Ma), where hipparionins are first recorded in the Vallès- Penedès Basi

Sistema de actividades para el desarrollo de la capacidad física de resistencia en las clases de Educación Física

The work that is presented gives an answer to the problem related with the development of the physical capacities, in particular, endurance, in the 8th grade Physical Education subject, for students girls. The objective is to design an activities system for the development of physical capacity of endurance during Physical Education lessons for the 8th grade girls of “Capitana Catalina Valdés” high school of Consolation del Sur municipality. There were used methods of the theoretical, empiric and statistical levels. The contribution to the theory is summed up in the systematizing of the theoretical foundations related with the formation and development of the physical capacities, with emphasis in endurance. Its practical significance resides in the implementation of the activities system that is proposed. The validation of it is carried out through the long duration run of 11 minutes, objective of the program that is applied as pedagogic tests before and after the implementation of the activities system, measuring the behavior of each one of the dimensions and more affected indicators, what demonstrates the effectiveness of it. The general theory of the system was approached, based on the components and didactic laws, principles where the developer teaching learning process is supported, which leads to the integral formation of the students girls and to the quality life improvement

A Benign Ovarian Tumour developing an Endometrial Cancer? Sertoliform Ovarian Cystoadenoma getting together with an Endometrioid Adenocarcinoma

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