27 research outputs found
Propriedades fĂsicoquĂmicas e avaliação da toxicidade aguda do extrato etanĂłlico padronizado a 70% das folhas de Mikania glomerata (Asteraceae)
- Author
- AULTON M.E.
- BOTSARIS A.S.
- BREMER K.
- CARDOSO M.LC
- CELEGHINI M.S.
- CROWL D.A.
- CUNHA C.L.
- DO AMARAL R.R.
- FAILACE R.
- FALCĂO H.S.
- FIERRO I.M.
- FLECKNELL P.
- GRAĂA C
- GUO A.
- HEBERLĂ G.
- HOLETZ F.B.
- IATSYNO A.I.
- KOHN D.F.
- LEITE M.G.R.
- LUCAS V.
- MAIORANO A.V.
- MALONE M.H.
- OLIVEIRA F.
- OLIVEIRA F.
- OLIVEIRA F.
- PANIZZA S.
- PIO CORRĂA M.
- PRESCOTT J.K.
- RITTER M.R.
- SALGADO H.R.N.
- SANTOS S.C.
- SOARES M.R.
- STANIFORTH J.N.
- SĂ R.C.S.
- TALEB-CONTINI S.H.
- TESKE M.
- VENEZIANI R.C.S.
- WANCZINSKI B.J.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2013
- Field of study
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
- Author
- A. Abd El-Aziz
- A. Abdul
- A. Agakhanyan
- A. Aggarwala
- A. Agrawal
- A. Al Mulla
- A. Al Naeemi
- A. Alfieri
- A. Ali
- A. Altun
- A. Alvarez D'Amelio
- A. Andersson
- A. Argena
- A. Austria
- A. Aydinlar
- A. Babyesiza
- A. Barai
- A. Barreau
- A. Barszcz
- A. Bartes
- A. Bazzoni Ruiz
- A. Beattie
- A. Bianchi
- A. Biernacka
- A. Black
- A. Blenkhorn
- A. Branjovich Tijuan
- A. Bremmelgaard
- A. Brown
- A. Browne
- A. Capucci
- A. Caspar
- A. Catanchin
- A. Chmielowski
- A. Choi
- A. Cieszynska
- A. Conde Y Bolado
- A. Connelly
- A. Cortada Cabrera
- A. Davids
- A. De Blasio
- A. De Wolf
- A. Dickerson
- A. Domenech Borras
- A. Dumikyan
- A. Edin
- A. Egilsson
- A. El-Etreby
- A. Elbahry
- A. Elorriaga Madariaga
- A. Espallargas
- A. Ewert
- A. Fearon
- A. Fedorowsky
- A. Ferreira-Jardim
- A. Ferrer
- A. Filippi
- A. Fleck
- A. Flynn
- A. Forero
- A. Frankiewicz
- A. Fujisawa
- A. Gallagher
- A. Ganatra
- A. Gegenhuber
- A. Gieroba
- A. Gilliland
- A. Giombolini
- A. Gonzales Segovia
- A. Grande Ruiz
- A. Grau
- A. Grytzmann
- A. Gubanov
- A. Guerrero Molina
- A. Guinand
- A. Haideri
- A. Hajimirsadeghi
- A. HallarÄker
- A. Halpin
- A. Hay
- A. Heer
- A. Heyse
- A. Horak
- A. Hot-Bjelac
- A. Howitt
- A. Iglesias Garcia
- A. Ishihara
- A. Ivanov
- A. Iñiguez Romo
- A. Jackun-Podlesna
- A. Jaremczuk-Kaczmarczyk
- A. Jarzebowski
- A. Jefferies
- A. Jekthammer
- A. Jerzewski
- A. John Camm
- A. John Camm
- A. John Camm
- A. Jones
- A. Kaczmarzyk-Radka
- A. Karczmarczyk
- A. Katta
- A. Kemmel
- A. Khan
- A. Khokhlov
- A. Koch
- A. Kolesnikova
- A. Kolodzinska
- A. Komlo
- A. Konopka
- A. Kopf
- A. Krueger
- A. Krzesiak-Lodyga
- A. Lavoie
- A. Lawande
- A. Lee
- A. Lettenström
- A. Leyva RendĂłn
- A. Lindberg
- A. Lindh
- A. Lindourkova
- A. Lischka-Lindner
- A. Lo Buglio
- A. Lopes
- A. Lopez
- A. Lucassen
- A. Ludkova
- A. Lysek-Jozefowicz
- A. Mannermyr
- A. Manzanal Rey
- A. Mariani
- A. Markiewicz
- A. Marquand
- A. Martin Vila
- A. Martinelli
- A. Maselli
- A. Matoltsy
- A. Mauric
- A. Meirino
- A. Menezes Lorga Filho
- A. Merliss
- A. Metzgier-Gumiela
- A. Mielot
- A. Mirtl
- A. Miyashita
- A. Mizuno
- A. Mowafy
- A. Murray
- A. Naguib
- A. Nagy
- A. Nakagomi
- A. Nakata
- A. Navarro
- A. Negrete Palma
- A. Negri
- A. Niemirycz-Makurat
- A. Nowak
- A. Nygaard
- A. Ohanissian
- A. Ohlsson
- A. Olofsson
- A. Ortiz
- A. Osberg
- A. Ota
- A. Oto
- A. Ovsannikova
- A. Page
- A. Papp
- A. Parkhomenko
- A. Pawelska-Buczen
- A. Pedersen
- A. Phrommintikul
- A. Pinter
- A. Pizzini
- A. Plauskat
- A. Podczeck-Schweighofer
- A. Postolache
- A. Pronk
- A. Pustelnik
- A. Quick
- A. Quietzsch
- A. Quisi
- A. Raczynska
- A. Raisaro
- A. Ramdass
- A. Reda
- A. Rodrigues
- A. Ross
- A. Sabir
- A. Sage
- A. Said
- A. Salinas
- A. Sapatyi
- A. Sasaki
- A. Scaccianoce
- A. Seoane Blanco
- A. Sidor
- A. Singal
- A. Skein
- A. Soliman
- A. Soma
- A. Sossich
- A. Spyropoulos
- A. Srinivas
- A. Sriwichian
- A. Stallinga-de Vos
- A. Steffens
- A. Suissa
- A. Sulc
- A. Svilaas
- A. Sword
- A. Szczepanska
- A. Szilagyi
- A. Szulowska
- A. Taguchi
- A. Talkenberger
- A. Tangsirira
- A. Tetlak
- A. Thatcher
- A. Therkelsen
- A. Thomson
- A. Tomasello
- A. Ushakov
- A. Vandorpe
- A. Vertes
- A. Vishnevsky
- A. Vonbank
- A. Wakeman
- A. Waldman
- A. Warke
- A. Wassef
- A. Wierzbicka
- A. Williams
- A. Wilson
- A. Wirdby
- A. Wutthimanop
- A. Yagensky
- A. Yoshimura
- A. Zateyshchikova
- A. Ăstrem
- A.-B. Ekstrand
- A.-K. Ascoop
- A.-M. Barbuto
- A.-M. Ohlin
- A.A. Damonte
- A.A. Fernandez
- A.B. Lensebraaten
- A.C. Billiaux
- A.C. Ingaramo
- A.C. Rothwell
- A.C. Tovar Castaneda
- A.C.P. Barretto
- A.D. Hrabar
- A.G. Ravi Shankar
- A.J. Kleiban
- A.J. McLeod
- A.L. Baek
- A.L. Cappi
- A.L. Tufare
- A.M. Jackson
- A.P. Drummond Wainstein
- A.P. Macagnan
- A.R. Kelsall
- A.R. Park
- A.S. Pandey
- Ajay K. Kakkar
- Ajay K. Kakkar
- Alex Parkhomenko
- Alex Spyropoulos
- Alexander G.G. Turpie
- Ali Oto
- Antonio Carlos Pereira Barretto
- B. Allasia
- B. Alzand
- B. Ayres
- B. Chatlaong
- B. Clarke
- B. Conway
- B. Coutu
- B. Crousillat
- B. Curyllo
- B. Deshpande
- B. Dolecka
- B. Doucet
- B. Dubois
- B. Dudzik-Richter
- B. Eriksson
- B. Fox
- B. Gaszner
- B. Ghezai
- B. Gosciniecka
- B. Hawkins
- B. Herrero Maeso
- B. Hoffmann
- B. Ikitimur
- B. Jacobson
- B. Jacobson
- B. Jansson
- B. Jimeno Besa
- B. Kurylo
- B. Kurylo
- B. Li
- B. Liu
- B. Lokesh
- B. Martinsson
- B. Mautner
- B. Merkely
- B. Mooso
- B. Naratreekoon
- B. Okopien
- B. Opielowska-Nowak
- B. Ostrowska-Pomian
- B. Racz
- B. Raghuraman
- B. Ramjattan
- B. Rzyczkowska
- B. Sarai
- B. Schaefer
- B. SchneeweiĂ
- B. Schweitzer
- B. Sievers
- B. Silaruks
- B. Singh
- B. Sinha
- B. Stephanie
- B. Strohmer
- B. Subbaraman
- B. Unterkircher
- B. Uppelschoten
- B. Vandrus
- B. Vanhauwaert
- B. Vishwanathan
- B. Vogel
- B. Voigts
- B. Ward
- B. Wollaert
- B. Wozakowska-Kaplon
- B. Zhou
- B.-T. Kellner
- B.A.J. Stockins Fernandez
- B.C. Jung
- B.E. Groenemeijer
- B.R. Park
- B.Y. Sayin
- Barry Jacobson
- Bernard J. Gersh
- C. A'Court
- C. Arabetti
- C. Astudillo
- C. Axthelm
- C. Batta
- C. Beltra
- C. Bergeron
- C. Bergeron
- C. Bester
- C. Boshoff
- C. Bothin
- C. Bouvy
- C. Bradshaw
- C. Brike
- C. Brotons Cuixart
- C. Bugueño Gutiérrez
- C. Buiks
- C. Bulla
- C. Buzzetti
- C. Cannon
- C. CantĂș Brito
- C. Chami
- C. Chigbo
- C. Ciabatta
- C. Conejeros
- C. Correa
- C. Corros Vicente
- C. Costantini Ortiz
- C. D'Arienzo
- C. Dias
- C. Dooldeniya
- C. DĂaz de la Vega
- C. Ellervik
- C. Femiano
- C. Fonseca
- C. Fritz
- C. Funosas
- C. Giles
- C. Gines Garcia
- C. Gomez
- C. GrÀssjö
- C. Guldener
- C. GĂłmez Pajuelo
- C. Hagn
- C. Hawkins
- C. HernĂĄndez Herrera
- C. Herrick
- C. Hines
- C. Houzvic
- C. Hutton
- C. Jacobs
- C. Jean
- C. Juergens
- C. Kongsin
- C. Lara
- C. Latella
- C. Lewis
- C. Liley
- C. Lodigiani
- C. Martinelli
- C. Mazzone
- C. McCarthy
- C. McIntosh
- C. Moncada
- C. Moro Serrano
- C. Mulholland
- C. Munhoz da Fontoura Tavares
- C. Mussap
- C. Nanzer Vital
- C. Nilsson
- C. Ogurusu
- C. Ormundo
- C. Orosco
- C. Ortiz Cortes
- C. Paul
- C. Pisani
- C. Queirantes
- C. Ramesh
- C. Ravenhorst
- C. Reichelt
- C. Reimer
- C. Rey
- C. Richard
- C. Ricotti
- C. Rivera Ramos
- C. Robertson
- C. Roca Saumell
- C. Rodrigo
- C. Santolaya
- C. Scarone
- C. Scheurwegs
- C. Schubert
- C. Schwencke
- C. Seamark
- C. Simon Valero
- C. Singh
- C. Singleton
- C. Smessaert
- C. Stoll
- C. Stöcklöcker
- C. Sugimoto
- C. Takanaka
- C. Thorsen
- C. Tondo
- C. Torres
- C. Treasure
- C. Vantomme
- C. Verdi
- C. Vicente
- C. Villan
- C. Wöhrer
- C. Yeo
- C. Zecca
- C.-J. Kim
- C.-J. Lindholm
- C.A. Almeida FernĂĄndez
- C.A. Neden
- C.C. Broilo França
- C.G. Foo
- C.H. Del Carlo
- C.H. Gimenez
- C.J. SĂĄnchez DĂaz
- C.K. Ching
- C.L. Bai
- C.L. Gonzalez Garcia
- C.M. Diaz Lopez
- C.P. Jones
- C.R. Costantini Frack
- C.R. Frack Costantini
- C.S. Lee
- Carlos Jerjes SĂĄnchez DĂaz
- Carmela Alonso
- Concepcion Alonso
- D. Adak
- D. Alpay
- D. Alvarez
- D. Amstutz
- D. Andrzejewski
- D. Aras
- D. Armaganijan
- D. Atar
- D. Belenky
- D. Bertolim Precoma
- D. Blaszczyk
- D. Buckert
- D. Cassidy
- D. Castro Fernandez
- D. Chemello
- D. Cholsaringkarl
- D. Colquhoun
- D. Conde
- D. Coulshed
- D. Cresp
- D. Crimmins
- D. Davies
- D. De Cleen
- D. Denie
- D. Diercks
- D. Eccleston
- D. Edwards
- D. Faes
- D. Farquhar
- D. Fielder
- D. Fitzmaurice
- D. Fitzpatrick
- D. Flores MartĂnez
- D. Fournier
- D. Galley
- D. Geatch
- D. Genc
- D. Glatzel
- D. Goodwin
- D. Gray
- D. Greyling
- D. Guanaes
- D. Guedj-Meynier
- D. Gulyas
- D. Ikeda
- D. Jackson
- D. Jain
- D. Kernick
- D. Kettles
- D. Kociolek
- D. Komar
- D. Konyushenko
- D. Kroll
- D. Kruczyk
- D. Kusiak
- D. Kustrzycka-Kratochwil
- D. Lesniewska-Krynska
- D. Leung
- D. Lopes
- D. LĂłpez Villezca
- D. Martinez Vasquez
- D. Merritt
- D. Michalik
- D. Montes
- D. Moreira
- D. Naik
- D. Nicolaus
- D. Nishijima
- D. O'Donnell
- D. Obadia
- D. Otero Tomera
- D. Platonov
- D. Plevak
- D. Poli
- D. Redpath
- D. Reimer
- D. Roy
- D. Rozewska-Furmanek
- D. Russell
- D. Sanchez
- D. Santos
- D. Seamark
- D. Shah
- D. Shah
- D. Shepherd
- D. Theodoro
- D. Tragen
- D. Uzun Alkan
- D. Van Lier
- D. Vandenbroeck
- D. Wright
- D. Zanolin
- D. Zateyshchikov
- D.-G. Shin
- D.-K. Kim
- D.B. Kim
- D.C. Esteves
- D.C. Sobral Filho
- D.D. Chen
- D.F. Cumberlidge
- D.H. Kim
- D.J. Choi
- D.R. Ryu
- D.W. Wang
- D.Y. Hu
- Dan Atar
- David A. Fitzmaurice
- David Fitzmaurice
- Dayi Hu
- E. Ahbeck
- E. Alborough
- E. Aleksandrova
- E. Banfi
- E. Barraquer Feu
- E. Bearez
- E. Bekieszczuk
- E. Belisario Falchetto
- E. Berge
- E. Blumberg
- E. Broton
- E. Buckley
- E. Burke
- E. Calvo Martinez
- E. Cardona Muñoz
- E. Chuquiure Valenzuela
- E. Corrihons
- E. Daros
- E. Davies
- E. Deweerd
- E. Domanska
- E. Ducasse
- E. EiĂfeller
- E. Ellie
- E. Eriksen
- E. EscrivĂĄ Montserrat
- E. Fernandes
- E. Fernandez Escobar
- E. Fernandez Mas
- E. Feys
- E. Fisher
- E. Fulop
- E. Gasior
- E. Gjertsen
- E. Gorbunova
- E. Hartranft
- E. Hettwer Magedanz
- E. Hevia Rodriguez
- E. Jaskulska-Niedziela
- E. Kamenska
- E. Kiralyhazine Gyorke
- E. Kis
- E. Kochanska
- E. Korczowska
- E. Kowal
- E. Krcova
- E. Kremis
- E. Kropacheva
- E. Lanna Figueiredo
- E. Lewicka
- E. Lichota
- E. Lileeva
- E. Loyd
- E. Lustosa
- E. LĂłpez Rosas
- E. Malone
- E. Mazur
- E. Mesolella
- E. Miedlar
- E. Molina
- E. Mollica Poeta
- E. MĂĄrquez Contreras
- E. Nagata
- E. Noori
- E. Novikova
- E. Okuyan
- E. Otaki
- E. Ozcelik
- E. Palmegiani
- E. Panchenko
- E. Pawlik-Rak
- E. Pena Garcia
- E. Polkanova
- E. Prochazkova
- E. Raymenants
- E. Rodriguez
- E. Saga
- E. Salomone
- E. Schaflinger
- E. Serralvo
- E. Shutemova
- E. Staniszewska
- E. Strieder
- E. Stuart
- E. Szuchnik
- E. Tiraferri
- E. Vanhalst
- E. Villeda Espinosa
- E. Watson
- E. Wilford
- E. Yakupov
- E. Yeter
- E. Yildirim
- E. Zaatout
- E. Zhuravleva
- E. Zidkova
- E. Zinka
- E.A. Choi
- E.B. Karaayvaz
- E.D. Alaguibe
- E.G. Lino
- E.H. Choi
- E.H. Lee
- E.J. Gonzalez Felix
- E.J. Yoon
- E.M. Esheiba
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- E.P. Gurfinkel
- E.R. Fernandes Manenti
- E.S. Heo
- Elizaveta Panchenko
- F. Ahmed
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- F. Yilmaz
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- F.E. Camazzola
- F.J. Bermudez Jimenez
- F.J. Zurbrigk
- F.R. Jaufeerally
- F.Z. Wang
- Frank Cools
- Frank Misselwitz
- Freek W.A. Verheugt
- G. Agnelli
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- G. Angel
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- G. Königer
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- G. Rehling
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- G. Starmer
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- G. SvÀrd
- G. Szalai
- G. Szantai
- G. Szumczyk-Muszytowska
- G. Tanabe
- G. Tarr
- G. Taylor
- G. Tian
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- G. Tobajas
- G. Trzcinski
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- G. Van Zon
- G. Vervoort
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- G. Yousef
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- G. Zubeeva
- G.-B. Eriksson
- G.-B. Nam
- G.-S. Hwang
- G.-U. Heinz
- G.A. Sambadaro
- G.B. Aranha Rosito
- G.H. Lee
- G.R. AraĂșjo
- G.R. de AraĂșjo
- G.S. Fu
- G.S. Zhang
- G.Z. Tao
- Giancarlo Agnelli
- Giuseppe Ambrosio
- Gloria Kayani
- Govindan Vijayaraghavan
- H. Aaröe
- H. Abdelrahman
- H. Adriaansen
- H. Ahlmark
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- H. Bae
- H. Begum
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- H. Burianova
- H. Capiau
- H. Chibana
- H. Choi
- H. Claussen
- H. Darius
- H. Date
- H. Dimitri
- H. Doi
- H. DomĂnguez
- H. Drexel
- H. Floegel
- H. Gibbs
- H. Handel
- H. Hey
- H. Hirayama
- H. Hohensee
- H. Hosokawa
- H. Ibsen
- H. Ikeda
- H. Inaba
- H. Jones
- H. Kakuda
- H. Kanai
- H. Kanda
- H. Kano
- H. Kato
- H. Kiat
- H. Kihara
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- Y. Maruyama
- Y. Matsuura
- Y. Mizuno
- Y. Moiseeva
- Y. Mostovoy
- Y. Niijima
- Y. Nishida
- Y. Nishihata
- Y. Oba
- Y. Onuki Pearce
- Y. Orlov
- Y. Osmolovskaya
- Y. Park
- Y. Saito
- Y. Sakamoto
- Y. Samejima
- Y. Santanakorn
- Y. Sasagawa
- Y. Sekine
- Y. Seta
- Y. Shapovalova
- Y. Shiina
- Y. Shimoyama
- Y. Shozawa
- Y. Stipp
- Y. Suzuki
- Y. Svyshchenko
- Y. Takagi
- Y. Tsuchiya
- Y. Ueyama
- Y. Vandekerckhove
- Y. Vorasettakarnkij
- Y. Wakasa
- Y. Ye
- Y. Yokoyama
- Y. Zhang
- Y.-I. Kim
- Y.H. Li
- Y.H. Sun
- Y.H. Yin
- Y.J. Yang
- Y.J. Yang
- Y.K. On
- Y.M. Chen
- Y.M. Lee
- Y.M. Sohn
- Y.R. Jeon
- Y.S. Oh
- Y.S. Son
- Y.S. Zhao
- Y.Y. Liu
- Ying Wang
- Yoichi Nakamura
- Yong Wang
- Yoshihisa Fujiura
- Yoshitake Fujiura
- Yuhei Shiga
- Yuichiro Nakamura
- Yukihiro Koretsune
- Yukio Shiga
- Z. Babjakova
- Z. Boda
- Z. Djaidani
- Z. Lajkowski
- Z. Laszlo
- Z. May
- Z. Monhart
- Z. Ongen
- Z. Radics
- Z.C. Lu
- Z.H. Zhou
- Z.M. Yang
- Publication venue
- Indian Heart J
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins
- Author
- Bandeira-Melo C
- Bandeira-Melo C
- Beckman BS
- Brezinski DA
- C.N. Serhan
- Chavis C
- Chiang N
- Chiang N
- Chiang N
- Christie PE
- Claria J
- Claria J
- Clish CB
- Clish CB
- Colgan SP
- Cotran RS
- Dahlen S-E
- Edenius C
- Feng Z
- Filep JG
- Fiore S
- Fiore S
- Fiore S
- Gewirtz AT
- Godson C
- Grandordy BM
- Gronert K
- Hachicha M
- I.M. Fierro
- Katoh T
- Lee TH
- Lee TH
- Leszczynski D
- Levy BD
- Levy BD
- Levy BD
- Maddox JF
- Maddox JF
- McMahon B
- Munger KA
- Papayianni A
- Pettitt TR
- Qiu FH
- Ramstedt U
- Sanak M
- Scalia R
- Schaldach CM
- Serhan CN
- Serhan CN
- Serhan CN
- Serhan CN
- Serhan CN
- Serhan CN
- Serhan CN
- Simchowitz L
- Sodin-Semrl S
- Stenke L
- Stenke L
- Takano T
- Tamaoki J
- Thomas E
- Wikstrosm Jonsson E
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins
- Author
- Publication venue
- Associação Brasileira de Divulgação CientĂfica
- Publication date
- 01/01/2001
- Field of study
Multicellular host responses to infection, injury or inflammatory stimuli lead to the formation of a broad range of chemical mediators by the host. The integrated response of the host is essential to health and disease; thus it is important to achieve a more complete understanding of the molecular and cellular events governing the formation and actions of endogenous mediators of resolution that appear to control the duration of inflammation. Lipoxins are trihydroxytetraene-containing lipid mediators that can be formed during cell-cell interactions and are predominantly counterregulators of some well-known mediators of inflammation. Since this circuit of lipoxin formation and action appears to be of physiological relevance for the resolution of inflammation, therapeutic modalities targeted at this system are likely to have fewer unwanted side effects than other candidates and current anti-inflammatory therapies. Here, we present an overview of the recent knowledge about the biosynthesis and bioactions of these anti-inflammatory lipid mediators
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins
- Author
- Publication venue
- Associação Brasileira de Divulgação CientĂfica
- Publication date
- Field of study
Multicellular host responses to infection, injury or inflammatory stimuli lead to the formation of a broad range of chemical mediators by the host. The integrated response of the host is essential to health and disease; thus it is important to achieve a more complete understanding of the molecular and cellular events governing the formation and actions of endogenous mediators of resolution that appear to control the duration of inflammation. Lipoxins are trihydroxytetraene-containing lipid mediators that can be formed during cell-cell interactions and are predominantly counterregulators of some well-known mediators of inflammation. Since this circuit of lipoxin formation and action appears to be of physiological relevance for the resolution of inflammation, therapeutic modalities targeted at this system are likely to have fewer unwanted side effects than other candidates and current anti-inflammatory therapies. Here, we present an overview of the recent knowledge about the biosynthesis and bioactions of these anti-inflammatory lipid mediators
ATL-1, a synthetic analog of lipoxin, modulates endothelial permeability and interaction with tumor cells through a VEGF-dependent mechanism
- Author
- A.M. Vieira
- Adam
- Addison
- Ades
- Alexander
- Arias-Pulido
- Baker
- Bissell
- C. Barja Fidalgo
- C.C. Figueiredo
- Cezar-de-Mello
- Cezar-de-Mello
- Chen
- Chiang
- Claffey
- ClĂ ria
- Dejana
- Dejana
- Dejana
- E.H. Neto
- Easwaran
- Eger
- Eliceiri
- Esser
- Ferrara
- Fierro
- Fierro
- Folkman
- Fong
- Franses
- GarcĂa-RomĂĄn
- Gavard
- Gavard
- Gavert
- Hanahan
- Hanahan
- Hartsock
- Hiratsuka
- Hoschuetzky
- I.M. Fierro
- Jaffe
- Jean
- Koch
- KĂŒsters
- Liu
- Mantovani
- McLachlan
- Michiels
- Nagy
- Nawroth
- Orsenigo
- Palmer
- Polyak
- Potter
- Rhee
- Schnittler
- Senger
- Serhan
- Shtivelband
- SimÔes
- Tinsley
- Ukropec
- V. Morandi
- van Beijnum
- van Muijen
- Vane
- Wang
- Weis
- Weis
- Yamaoka-Tojo
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Effect of GnRH or hCG administration on Day 4 post insemination on reproductive performance in Merino sheep of North Patagonia
- Author
- A.E. Gibbons
- A.T. Soto
- Bartolome
- Bartolome
- Bazer
- Beck
- Bolet
- Cam
- Cam
- Catalano
- Cavalcanti
- Chenoweth
- Cueto
- De Kruif
- Diskin
- Farin
- Fernandez
- Fierro
- Fierro
- Fukui
- GarcĂa-Pintos
- Garrett
- Gibbons
- Hashem
- I.M. Lacau- Mengido
- Ishida
- J. Fernandez
- Kenyon
- Khan
- Khan
- Khan
- Kittok
- Kleemann
- Lankford
- Lashari
- Lashari
- LĂłpez-Gatius
- M.I. Cueto
- M.M. Bruno- Galarraga
- Mirzaei
- Moeini
- Moeini
- Nancarrow
- Nephew
- Newcombe
- Olfati
- R Core Team
- R.L. de la Sota
- Rostami
- Russel
- Santos
- Satterfield
- Schmitt
- Sirjani
- Wilmut
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Dynamics of Ca2+ and Na+ in the dendrites of mouse cerebellar Purkinje cells evoked by parallel fibre stimulation
- Author
- Burnashev N.
- Callaway J.C.
- Callaway J.C.
- Carter T.D.
- Denk W.
- Eccles J.C.
- Eilers J.
- Farrant M.
- Fierro L.
- Fierro L.
- Ghosh A.
- Hausser M.
- Hille B.
- Hollmann M.
- Inoue T.
- Ito M.
- Jacoby S.
- Keinanen K.
- Kohda K.
- Konishi M.
- Konnerth A.
- Konnerth A.
- Kuwajima G.
- Lev-Ram V.
- Llinas R.
- Maruyama T.
- Merrill E.G.
- Miyakawa H.
- Nakanishi S.
- Nohmi M.
- Ogden D.
- Perkel D.J.
- Raman I.M.
- Reynolds T.
- Ross W.N.
- Sakurai M.
- Sommer B.
- Tempia F.
- Yuzaki M.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Immunocompromised patients with acute respiratory distress syndrome : Secondary analysis of the LUNG SAFE database
- Author
- Abad R.D.
- Abe Toshikazu
- Abroug Fekri
- Adams J.C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguirre Janet S
- Aguirre-Bermeo Hernan
- Aisa T.M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi H.M.
- Al Jabbary A.S.
- Albaiceta G.M.
- Albarrak M.M.
- Albiero Daniela
- Alda R.S.
- Alejandro Risso V.
- Alexander P.
- Alfonso Alec A.Tallet
- Algaba Ă.
- Aliaga Felipe A.
- Alisasis A.U.
- Allan R.M.
- Allue R.M.
- Almekhlafi G.
- Alonso J.G.
- Altaf Wahid
- Alvarez A.M.
- Alvarez Javier
- Amin P.
- Amir Fahd
- Amor M.
- An Youzhong
- Andersen F.H.
- Andoh Kohkichi
- Andruszkiewicz P.
- Aneman Anders
- Antonelli Massimo
- AntĂŽnio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Y.M.
- Araujo A.M.
- Arizmendi A.
- Arnal Jean-Michel
- Artiga M.J.D.
- Artigas A.
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo L.C.
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey M.B.
- Bajwa E.
- Balkhi H.
- Baltus Thomas
- Banner-Goodspeed V.M.
- Barberet Guillaume
- Baron Rebecca M
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros F.M.
- Barros N.C.
- Batra H.
- Battle C.E.
- Bauer P.R.
- Beck Eduardo
- Beck O.
- Bedreag O.H.
- Beegle S.H.
- Beitler J.R.
- Bellani Giacomo
- Beloncle François
- Benslama A.
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz.
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Binti Pengiran Haji Ismail Dayangku Hajah Maizatul Aiman
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman T.C.
- Blanco J.
- Bolon S.
- Borello Silvana A.
- Borotto Erika E.
- Botteri Marco
- Bouchoucha Slaheddiine
- Boukhazna Messabi
- Bouw M.J.
- Boyd O.
- Bramall J.
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito V.A.
- Brizuela Matias
- Broman Lars M.
- Brown S.M.
- Browne T.S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns M.M.
- Buensuseso J.A.
- Bugedo G.
- Buise M.P.
- Bulpa Pierre Alain
- Bumbasierevic V.
- Bumbasirevic Vesna
- Burtenshaw A.J.
- Burtin Philippe
- Buzancais Gautier
- BĂ©duneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz C.
- Cardonnet Luis P.
- Careless J.P.
- Carpentier Dorothée
- Carreño Nicolås G.
- Carteaux Guillaume
- Casalena Paolo
- Casement J.
- Castro A.G.
- Castro S.
- Catorze N.T.
- Cazorla-Barranquero F.G.
- Ceniceros-Barros A.
- Cereijo E.
- Cerny V.
- Cerrato Valeria I.
- Cervantes M.R.
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman R.
- Chau S.K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng M.P.
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry S.
- Christiansen Aage
- Cimic N.
- Cinnella Gilda
- Cirone Rob
- CitalĂĄn Johanna E.
- Claraco-Vega L.M.
- Clarkson Kevin P.
- Claverias Laura
- Cohen J.E.
- Cole J.M.
- Collins Daniel V.
- Collyer T.
- Colombo Ricardo
- Combaux Daniele M.
- Combes Alain
- Conti S.
- Cooper R.
- Coppadoro Andrea
- Corneci D.E.
- Cortegiani Andrea
- Cortez Cesar A.
- Coxo C.M.
- Cracchiolo Andrea N.
- Cranshaw J.H.
- Crapelli Giulia
- Crouch D.R.
- Crova Philippe J.
- Csabi P.
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric.
- Daubin CĂ©dric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson H.
- de Cima-Iglesias S.
- de Gordoa L.O.R.
- de Haro C.
- de Pablo R.
- de Prost Nicolas
- Dean M.N.
- Declercq Pierre-Louis M.
- Dector D.
- Dector D.M.
- Deicas A.
- Dellamonica Jean
- Dellera Christian
- Delsing A.
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane T.
- Depuydt Pieter
- Derman Suleyman S.
- Di Tomasso Nora N.
- Di Yu D.
- Diaz-Rodriguez Esther
- Dive Alain M.
- Dixit Subhal B.
- do Vale Fernandes A.
- Dolva M.S.
- Donnelly A.
- Dowling A.T.
- Doyen Denis
- Dres Martin
- Dreyer K.R.
- Dunne Eimhin S.
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- DĂ©mpair G.
- Ebeid A.
- Elatrous Souheil
- Elisabet Garcia M.
- Elkhayari M.
- Ellis Helen E.
- Elmasri M.
- Erbabacan Emre
- Eriksson Karin E.
- Estenssoro Elisa
- Esteve F.
- Estilita J.M.
- Estrella C.R.
- Ezzouine Hanane
- Fan E.
- Fartoukh Muriel
- FarĂas Pamela A.
- Fawkes Danielle A.
- Ferguson Andrew
- Ferguson Niall D.
- Fernandez Adriana M.
- Fernandez Ruben O.
- Fierro J.M.
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C.
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franco N.
- Francois Guy M.
- França A.G.
- Frati Elena
- Frendl Gyorgy
- Frigyik A.D.
- Fusari Maurizio
- Futami Satoru
- Gally Josette
- Ganesan Deeban
- Gao Yuan N.
- Gao Yuan N.
- Garcia Patricio H.
- Gazenkampf A.A.
- Gelée Bruno
- George F.G.
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis S.
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C.
- Gomaa D.
- Gomes R.M.
- Gomez Pablo E.
- Gomez-Flores S.S.
- Gonzalez D.R.
- Gonzalez M.
- GonzĂĄlez R.M.
- GonzĂĄlez-Salamanca Ăngela
- Gonçalves Claudio H.
- Goodson Jennifer C
- Gordo F.
- Gosselin R.J.
- Goubaux Bernard
- Grasselli Giacomo
- Graziani Romano
- Gregoretti Cesare
- Grelon Fabien
- Griffin Ruth
- Grigoriev E.
- Grijalba C.Q.
- Grissom C.K.
- Gritsan A.I.
- Grubissich Nicolas
- Gueret R.M.
- Gurjar Mohan
- Guttormsen A.B.
- Guérin Claude
- GĂłmez P.R.A.
- Hacking D.J.
- Haddad Youssef
- Hadfield Dan
- Hagan S.J.
- Han Hui
- Han Yi
- Hang Ai Y.
- Hanlon Gabrielle C.
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian Seyed Mohammadreza
- Hashida Tomoaki
- He Z.
- Hedlund Lars
- Heidari Farshad
- Heines S.J.
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne.
- Hermosa C.
- Hessell R.J.
- Heunks L.M.
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia T.
- Hopf Hans-Bernd F.
- Hopkins Phil
- Hormis Anil P.
- Hou Peter C.
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X.
- Huang Qing Q.
- Huang Xiao B.
- Huerta Francisco P.
- Huff N.G.
- Humphreys Sally K.
- Hunt A.
- Hurtado J.
- Hutchison R.A.
- Hutton Paula J.
- Ibañez-Santacruz M.
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P.
- Imperio M.C.
- Insaurralde Carolina S.
- Inskip Deborah M.
- Ioannou N.
- Iotti Giorgio A.
- Irvine Donald A
- Ismail D.
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F.
- Jakubowska K.
- Jamaati Hamidreza
- Jarquin-Badiola Y.D.
- Jassal Mandeep
- Javeed Areej
- Jha Rajeev R.
- Jiang Liangyan
- Jibaja M.
- Jimenez Antonio G.
- Jochmans SĂ©basien
- Jog Sameer A.
- Jovanovic Bojan
- Judy C.
- Jurado M.T.
- Kadaba Varsha
- Kajtor I.
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff M.
- Kamel G.
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana G.
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir F.
- Kheir F.M.
- Kimura Hiroyasu
- Kiourtzieva Ellada V.
- Kitch B.T.
- Knapman Karl M.
- Knoll Jenny
- Knowles Serena
- Kol Mark R.
- Kong Jing
- Koyama Kansuke
- Krabler Jens
- Krstevski Amanda
- Kulkarni S.
- Kumar Alek
- Kurahashi K.
- Kusumoto Kohei
- Laake Jon Henrik
- Labarca Eduardo F.
- Laffey John G.
- Lamb K.D.
- Lanspa M.J.
- Larsson A.
- Larsson Niklas
- Lebbinck Herve
- Lee J.
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus J.S.
- Leon Yoshido H.H.
- Li Bin
- Li Qingdong
- Li Qiong J.
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan Y.
- Li-Xin Zhou
- Liew Kong Y.
- Ling Long L.
- Liu Haitao
- Liu Jian
- Liu Jing L.
- Liu Ling
- Llano Miguel
- Llinares Moya David D.
- Lohner Ralph
- Loiacono Flavia A.
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado J.C.
- Lora F.S.
- Lora Pilar
- Lorente J.A.
- Lorente M.d.C.
- Losada E.P.
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Palazon Sanchez Eugenio
- Luo Xiaoming
- Lynch Joan M.
- LĂłpez-Messa J.B.
- Maazouzi W.
- Macfadyen R.
- MacFie C.C.
- Madotto Fabiana
- Maeyama Hiroki N.
- Maghrabi K.A.
- Magret Monica
- Mahto Heera L.
- Mancebo Jordi
- Manoharan Venika
- Marcos D.P.
- Marcu A.
- Marin Julien
- Marin M.C.
- Martinez Felipe T.
- Marum S.M.
- Massa Eleni V.
- Mataloun Sergio
- Matamis D.
- Matsumoto Shunei
- Mattei Alessia
- May M.M.
- Mcarthur C.
- McAuley Danny
- Mccalman K.H.
- Mckechnie Stuart
- Mckee Raymond
- Mckenna Toni E.
- Mcleod A.
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- Meaney Edel A.
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia F.J.F.
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar T.
- Messias A.M.
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T.
- Miller Jennene J.
- Miller R.R.
- Mirabella Lucia
- Mizuguchi Ichiko
- Moal Charlene Le
- Mochizuki Katsunori
- Mohr N.M.
- Mojoli Francesco
- Moles S.I.
- Molin A.lexandre
- Montanha G.M.
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- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K.
- Mukkera S.R.
- Mustafa G.M.
- Muthuchellappan Radhakrishnan
- MĂĄca Jan
- Nagy Eva O.
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Antonio P.
- Nasu Michitaka
- Navalpotro M.A.B.
- Navarra L.
- Navarro G.
- Neal John
- Negoita S.I.
- Newby L.
- Nichol Alistair
- Nielsen Jonas
- Niimi Daisuke
- Nin N.
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark K.A.
- Nunci Lordian
- Nunes Silvia L.
- Nunomiya Shin
- Nutt Christopher
- Nuñez E.
- Nygren Ingela
- O'Croinin Donall
- O'Muircheartaigh Aogan C.
- Occhipinti Giovanna
- Oetting T.W.
- Ogino Yasuaki
- Oikonomou Marina A.
- Okane S.C.
- Okuda Nao
- Oldroyd M.G.
- Olga M.F.
- Oliveira B.S.
- Oneill Orla
- Ortiz Claudia A.
- Oscanoa F.A.M.
- Osman Emilio M.
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L.
- Ozcelik Meneske
- Palaniswamy Vijayanand
- Palma Daniela M.
- Palmese Salvatore
- Palo J.E.
- Panarello Giovanna
- Papanikolaou Metaxia N.
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- Papazian Laurent
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- Para L.H.
- Parhar Ken
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- Patroniti NicolĂČ
- Pattarino Pierpaolo Terragni Ilaria
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- Pellegrini CarlosA.
- Pelletier Nicolas
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- Persson Linnea
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- Pham Tai
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- Pittini G.
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- Pozo Norberto C.
- Pozzi Matteo
- Preez P.D.
- Prieto-GonzĂĄlez M.
- Pronovost Antoine
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H.
- Qin Tie H.
- Qiu Haibo
- Raaijmakers M.
- Rabboni Francesca
- Rafael Sanchez I.
- Raimondi Ferdinando
- Raj Ashok S.
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J.
- Ramirez-Alfaro Christian M.
- Ramirez-Gutierrez A.
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- Ranero J.L.
- Raponi Francesco
- Recio Noelia N.
- Reschreiter Henrik
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- Reynolds Claire.
- Rhayakar Rachana V.
- Rialp G.
- Richecoeur Jack R.
- Ricome Sylvie
- Rigaud Jean-Philippe.
- Rinia M.
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- Rodriguez Lucia L.
- Rodriguez R.
- Rojas Manuel A.GonzĂĄlez
- Rosa JonasI.
- Roser T.P.
- Rossi Anna
- Roux Damien
- Rugonfalvi Szabolcs
- Ruiz S.R.
- Ruiz-Aguilar A.L.
- Rylander ChristianC.
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D.
- Saenz MarĂa G.
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- Sagar Sudha V.
- Saito Koji
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- Samkaoui N.
- Sanchez R.J.
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- Sanchez-Medina J.R.
- Sandesc D.
- Santoli Francesco L.
- Santos C.
- Sauvadet Elise P.
- Savioli Monica
- Scafetti Sergio
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schiöler Fredrik
- Schlichting A.B.
- Schneider Francis
- Schomer Ashley
- Schouten J.A.
- Schuetz Michael
- Schultz M. J.
- SchÀfer Susanne
- Scott Christopher J.
- Seasman Colette
- Seethala Raghu
- Sellors G.P.
- Seoane-Quiroga L.
- Serra Aurelia I.M.
- Serra C.
- Setten Mariano G.
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn J.O.
- Shiozaki Kyoko
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- Silesky J.
- Sim M.
- Simon Philipp
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- Sivashanmugavel M.
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- Sottiaux T.
- Souissi Asma Ben
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E.
- Staudinger Thomas
- Stephenson L.
- Stewart R.
- Stigler W.
- Strauch U.
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds S.
- Szakmany T.
- SĂĄnchez Rocio Manzano
- SĂĄnchez-Ballesteros JesĂșs
- SĂžreide E.
- Tabhan E.
- Tabhan E.E.
- Tainter C.
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tan B.C.
- Tanaka Hroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano S.
- Terzi Nicolas
- Thibault Sandrine
- Thomas Matthew
- Thompson Marlus M.
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu D.R.
- Toribio D.P.
- Toth-Tarsoly P.
- Treanor Nuala
- Trinder T.J.
- Trinidad O.A.
- Tulaimat A.
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Universitat AutĂČnoma de Barcelona
- Unnikrishnan Rammesh
- Uppalapati A.
- Van Haren Frank
- Van Wezel H.M.
- Vargas Monica P.
- Vascotto Ettore R.
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez A.
- Villagomez A.J.
- Villamagua Boris G.
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
- Warren J.
- Watanabe Eizo
- Watt Philip
- Welters I.D.
- Wenham T.
- Wessbergh Joanna
- Whitehead Christina
- Willett E.L.
- Williams A.J.
- Williams K.E.
- Wise M.P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall D.W.
- Wrigge H.
- Wu Ya Q.
- Xin-Hua Qiang
- Xu Yinghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts D.J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste L.J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua K.S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao H.
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie
- Zumaran Aguilar Ronald
- Ăamendys-Silva S.A.
- ĂŒnal Necmettin
- Publication venue
- Publication date
- 01/01/2018
- Field of study
The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
The Neutrophil
- Author
- A. Ashkenazi
- A. Casadevall
- A. Chuntharapai
- A. Lee
- A. Ludwig
- A. Meier
- A. Roeder
- A. Schaffner
- A.B. Spriel van
- A.B. Spriel van
- A.B. Spriel van
- A.D. Luster
- A.I. Medeiros
- A.M. Condliffe
- A.R. Waldorf
- B. Mehrad
- B. Mehrad
- B. Zhong
- B.-A. Au
- C. Du
- C. Gil-Lamaignere
- C. Haslett
- C. Martin
- C. Monari
- C. Monari
- C. Monari
- C. Palma
- C.A. Lyman
- C.L. Frey
- C.L. Ivey
- D.E. Morgenstern
- D.L. Danley
- D.R. Green
- E. Balish
- E. Kitchen
- E. Lukasser-Vogl
- E. Roilides
- E.A. Kurt-Jones
- E.D. Tomhave
- E.F. Foxman
- E.H. Smail
- F. Colotta
- F. Hayashi
- F.E. Coenjaerts
- G.D. Brown
- G.E. Morris
- G.M. Fuhler
- H. Ali
- H.A. Edens
- H.U. Simon
- I. Sabroe
- I. Sabroe
- I. Sabroe
- I. Sabroe
- I. Sabroe
- I. Sabroe
- I. Sabroe
- I.M. Fierro
- J. Geiger
- J. Savill
- J. Sturtevant
- J.A. Lovchik
- J.E. Pease
- J.E. Wang
- J.L. Gao
- J.M. Adams
- J.N. Galgiani
- J.N. Galgiani
- J.N. Galgiani
- J.R. White
- K. Kawakami
- K. Matsushima
- K.A. Cadwallader
- L. Allen
- L. Christin
- L. Del Rio
- L. Romani
- L.A. Jackson
- L.R. Hall
- L.R. Usher
- M. Hachicha
- M. Wellington
- M.D. Richardson
- M.G. Netea
- M.G. Netea
- M.G. Netea
- M.M. Lipovsky
- N. Kurita
- N.A. Thornberry
- P. Cohen
- P.C. Burdon
- P.J. Tacken
- P.L. Podolin
- P.M. Ellerbroek
- R. Bonecchi
- R.A. Schnur
- R.D. Diamond
- R.M. Richardson
- S. Akira
- S. Bellocchio
- S. Bellocchio
- S. Shoham
- S.A. Jones
- S.I. Simon
- S.L. Newman
- S.M. Levitz
- S.S. Mambula
- T. Doroshenko
- T. Jouault
- T. Kawai
- T. Madan
- T. Murayama
- T. Valerius
- T. Yoshimura
- T. Yoshimura
- T. Yoshimura
- T.J. Schall
- U.E. Hopken
- V.A. Fadok
- W. Fu
- W. Huang
- W.C. Liles
- Y. Aratani
- Z.M. Dong
- Z.M. Dong
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study