646 research outputs found
Linear stability analysis of transverse dunes
Sand-moving winds blowing from a constant direction in an area of high sand
availability form transverse dunes, which have a fixed profile in the direction
orthogonal to the wind. Here we show, by means of a linear stability analysis,
that transverse dunes are intrinsically unstable. Any along-axis perturbation
on a transverse dune amplify in the course of dune migration due to the
combined effect of two main factors, namely: the lateral transport through
avalanches along the dune's slip-face, and the scaling of dune migration
velocity with the inverse of the dune height. Our calculations provide a
quantitative explanation for recent observations from experiments and numerical
simulations, which showed that transverse dunes moving on the bedrock cannot
exist in a stable form and decay into a chain of crescent-shaped barchans.Comment: 8 pages, 4 figure
Collapsing granular suspensions
A 2D contact dynamics model is proposed as a microscopic description of a
collapsing suspension/soil to capture the essential physical processes
underlying the dynamics of generation and collapse of the system. Our physical
model is compared with real data obtained from in situ measurements performed
with a natural collapsing/suspension soil. We show that the shear strength
behavior of our collapsing suspension/soil model is very similar to the
behavior of this collapsing suspension soil, for both the unperturbed and the
perturbed phases of the material.Comment: 7 pages, 5 figures, accepted for publication in EPJ
Attitudes of sperm donors towards offspring, identity release and extended genetic screening
Research question
What is sperm donors’ attitude towards offspring, anonymity and extended genetic screening?
Design
An online questionnaire for sperm donors was administered at Cryos International in the USA and Denmark between 9 and 30 September 2020. A total of 233 donors (37 in the USA and 196 in Denmark) completed the questionnaire. This study is unique because it was performed in a setting that allows donors to choose to be either ID-release or non-ID-release donors.
Results
Most donors had two motives to donate: helping childless people and/or financial compensation. ID-release donors differed significantly from non-ID-release donors in numerous aspects of the donation, including relationships with the offspring, information sharing with others and wanting information about offspring. In general, donors had a very positive attitude towards genetic testing and extended genetic screening.
Conclusions
Offering the possibility for donors to be either ID-release or non-ID-release allows more donors to be recruited than if only one option were available. The multiple differences between the two donor types suggests that these are groups with profoundly different attitudes towards donation. The general attitude of donors towards genetic testing and expanded genetic screening is very positive but further studies on the attitude of candidate donors are needed
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents
Academic achievement in adolescents is correlated with 1-carbon metabolism (1-CM), as folate intake is positively related and total plasma homocysteine (tHcy) negatively related to academic success. Because another 1-CM nutrient, choline is essential for fetal neurocognitive development, we hypothesized that choline and betaine could also be positively related to academic achievement in adolescents. In a sample of 15-yr-old children (n = 324), we measured plasma concentrations of homocysteine, choline, and betaine and genotyped them for 2 polymorphisms with effects on 1-CM, methylenetetrahydrofolate reductase (MTHFR) 677C>T, rs1801133, and phosphatidylethanolamine N-methyltransferase (PEMT), rs12325817 (G>C). The sum of school grades in 17 major subjects was used as an outcome measure for academic achievement. Lifestyle and family socioeconomic status (SES) data were obtained from questionnaires. Plasma choline was significantly and positively associated with academic achievement independent of SES factors (paternal education and income, maternal education and income, smoking, school) and of folate intake (P = 0.009, R2 = 0.285). With the addition of the PEMT rs12325817 polymorphism, the association value was only marginally changed. Plasma betaine concentration, tHcy, and the MTHFR 677C>T polymorphism did not affect academic achievement in any tested model involving choline. Dietary intake of choline is marginal in many adolescents and may be a public health concern
A Systematic Review of Patients’ Values, Preferences, and Expectations for the Diagnosis and Treatment of Male Lower Urinary Tract Symptoms
Context: Understanding men's values and preferences in the context of personal, physical, emotional, relational, and social factors is important in optimising patient counselling, facilitating treatment decision-making, and improving guideline recommendations. Objective: To systematically review the available evidence regarding the values, preferences, and expectations of men towards the investigation and treatment (conservative, pharmacological, and surgical) of male lower urinary tract symptoms (LUTS). Evidence acquisition: We searched electronic databases until August 31, 2020 for quantitative and qualitative studies that reported values and preferences regarding the investigation and treatment of LUTS in men. We assessed the quality of evidence and risk of bias using the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) and GRADE Confidence in the Evidence from Reviews of Qualitative Research (CERQual) approaches. Evidence synthesis: We included 25 quantitative studies, three qualitative studies, and one mixed-methods study recruiting 9235 patients. Most men reported urodynamic testing to be acceptable, despite discomfort or embarrassment, as it significantly informs treatment decisions (low certainty evidence). Men preferred conservative and less risky treatment options, but the preference varied depending on baseline symptom severity and the risk/benefit characteristics of the treatment (moderate certainty). Men preferred pharmacological treatments with a low risk of erectile dysfunction and those especially improving urgency incontinence (moderate certainty). Other important preference considerations included reducing the risk of acute urinary retention or surgery (moderate certainty). Conclusions: Men prefer lower-risk management options that have fewer sexual side effects and are primarily effective at improving urgency incontinence and nocturia. Overall, the evidence was rated to be of low to moderate certainty. This review can facilitate the treatment decision-making process and improve the trustworthiness of guideline recommendations. Patient summary: We thoroughly reviewed the evidence addressing men's values and preferences regarding the management of urinary symptoms and found that minimising adverse effects is particularly important. Further research to understand other factors that matter to men is required. (C) 2020 European Association of Urology. Published by Elsevier B.V. All rights reserved.Peer reviewe
Measurement of Pion Enhancement at Low Transverse Momentum and of the Delta-Resonance Abundance in Si-Nucleus Collisions at AGS Energy
We present measurements of the pion transverse momentum (p_t) spectra in
central Si-nucleus collisions in the rapidity range 2.0<y<5.0 for p_t down to
and including p_t=0. The data exhibit an enhanced pion yield at low p_t
compared to what is expected for a purely thermal spectral shape. This
enhancement is used to determine the Delta-resonance abundance at freeze-out.
The results are consistent with a direct measurement of the Delta-resonance
yield by reconstruction of proton-pion pairs and imply a temperature of the
system at freeze-out close to 140 MeV.Comment: 12 pages + 4 figures (uuencoded at end-of-file
Hadron yields and spectra in Au+Au collisions at the AGS
Inclusive double differential multiplicities and rapidity density
distributions of hadrons are presented for 10.8 A GeV/c Au+Au collisions as
measured at the AGS by the E877 collaboration. The results indicate that large
amounts of stopping and collective transverse flow effects are present. The
data are also compared to the results from the lighter Si+Al system.Comment: 12 pages, latex, 10 figures, submitted to Nuclear Physics A (Quark
Matter 1996 Proceedings
Chiral Symmetry and light resonances in hot and dense matter
We present a study of the scattering amplitude in the and
channels at finite temperature and nuclear density within a chiral
unitary framework. Meson resonances are dynamically generated in our approach,
which allows us to analyze the behavior of their associated scattering poles
when the system is driven towards chiral symmetry restoration. Medium effects
are incorporated in three ways: (a) by thermal corrections of the unitarized
scattering amplitudes, (b) by finite nuclear density effects associated to a
renormalization of the pion decay constant, and complementarily (c) by
extending our calculation of the scalar-isoscalar channel to account for finite
nuclear density and temperature effects in a microscopic many-body
implementation of pion dynamics. Our results are discussed in connection with
several phenomenological aspects relevant for nuclear matter and Heavy-Ion
Collision experiments, such as mass scaling vs broadening from dilepton
spectra and chiral restoration signals in the channel. We also
elaborate on the molecular nature of resonances.Comment: 14 pages, 14 figures. Contribution to Hard Probes 2008, Illa de A
Toxa, Spain, June 8th-14th 200
Prevalence and spatial analysis of antileptospiral agglutinins in dairy cattle - Microregion of Sete Lagoas, Minas Gerais, 2009/2010
Model for a dune field with exposed water table
Aeolian transport in coastal areas can be significantly affected by the
presence of an exposed water table. In some dune fields, such as in
Len\c{c}\'ois Maranhenses, northeastern Brazil, the water table oscillates in
response to seasonal changes of rainfall and rates of evapotranspiration,
rising above the ground during the wet season and sinking below in the dry
period. A quantitative understanding of dune mobility in an environment with
varying groundwater level is essential for coastal management as well as for
the study of long-term evolution of many dune fields. Here we apply a model for
aeolian dunes to study the genesis of coastal dune fields in presence of an
oscillating water table. We find that the morphology of the field depends on
the time cycle, , of the water table and the maximum height,
, of its oscillation. Our calculations show that long chains of
barchanoids alternating with interdune ponds such as found at Len\c{c}\'ois
Maranhenses arise when is of the order of the dune turnover
time, whereas dictates the growth rate of dune height with
distance downwind. We reproduce quantitatively the morphology and size of dunes
at Len\c{c}\'ois Maranhenses, as well as the total relative area between dunes.Comment: 12 pages, 12 figure
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