386 research outputs found
Coupled superconducting qudit-resonator system: Energy spectrum, state population, and state transition under microwave drive
Superconducting quantum multilevel systems coupled to resonators have recently been considered in some
applications such as microwave lasing and high-fidelity quantum logical gates. In this work, using an rf-SQUID
type phase qudit coupled to a microwave coplanar waveguide resonator, we study both theoretically and
experimentally the energy spectrum of the system when the qudit level spacings are varied around the resonator
frequency by changing the magnetic flux applied to the qudit loop. We show that the experimental result can
be well described by a theoretical model that extends from the usual two-level Jaynes-Cummings system to the
present four-level system. It is also shown that due to the small anharmonicity of the phase device a simplified
model capturing the leading state interactions fits the experimental spectra very well. Furthermore we use the
Lindblad master equation containing various relaxation and dephasing processes to calculate the level populations
in the simpler qutrit-resonator system, which allows a clear understanding of the dynamics of the system under
the microwave drive. Our results help to better understand and perform the experiments of coupled multilevel
and resonator systems and can be applied in the case of transmon or Xmon qudits having similar anharmonicity
to the present phase device.This work was supported by the Ministry of Science and Technology of China (Grants No. 2014CB921202, No. 2015CB921104, and No. 2016YFA0300601),the National Natural Science Foundation of China (Grants No. 91321208 and No. 11674380)the Key Research Program of the Chinese Academy of Sciences (Grant No. XDPB08-3)S.H. acknowledges support by the US NSF (PHY-1314861)
Is traditional Chinese medicine recommended in Western medicine clinical practice guidelines in China? A systematic analysis
BackgroundEvidence-based medicine promotes and relies on the use of evidence in developing clinical practice guidelines (CPGs). The Chinese healthcare system includes both traditional Chinese medicine (TCM) and Western medicine, which are expected to be equally reflected in Chinese CPGs.ObjectiveTo evaluate the inclusion of TCM-related information in Western medicine CPGs developed in China and the adoption of high level evidence.MethodsAll CPGs were identified from the China Guideline Clearinghouse (CGC), which is the main Chinese organisation maintaining the guidelines issued by the Ministry of Health of China, the Chinese Medical Association and the Chinese Medical Doctors’ Association.TCM-related contents were extracted from all the CPGs identified. Extracted information comprised the institution issuing the guideline, date of issue, disease, recommendations relating to TCM, evidence level of the recommended content and references supporting the recommendations.ResultsA total of 604 CPGs were identified, only a small number of which (74/604; 12%) recommended TCM therapy and only five guidelines (7%) had applied evidence grading. The 74 CPGs involved 13 disease systems according to the International Classification of Diseases 10th edition. TCM was mainly recommended in the treatment part of the guidelines (73/74, 99%), and more than half of the recommendations (43/74, 58%) were related to Chinese herbal medicine (single herbs or herbal treatment based on syndrome differentiation).ConclusionsFew Chinese Western medicine CPGs recommend TCM therapies and very few provide evidence grading for the TCM recommendation. We suggest that future guideline development should be based on systematic searches for evidence to support CPG recommendations and involve a multidisciplinary approach including TCM expertise
Generalized holonomy of M-theory vacua
The number of M-theory vacuum supersymmetries, 0 <= n <= 32, is given by the
number of singlets appearing in the decomposition of the 32 of SL(32,R) under H
\subset SL(32,R) where H is the holonomy group of the generalized connection
which incorporates non-vanishing 4-form. Here we compute this generalized
holonomy for the n=16 examples of the M2-brane, M5-brane, M-wave, M-monopole,
for a variety of their n=8 intersections and also for the n>16 pp waves.Comment: 24 pages, LaTe
Examining the Higgs boson potential at lepton and hadron colliders: a comparative analysis
We investigate inclusive Standard Model Higgs boson pair production at lepton
and hadron colliders for Higgs boson masses in the range 120 GeV < m_H < 200
GeV. For m_H < 140 GeV we find that hadron colliders have a very limited
capability to determine the Higgs boson self-coupling, \lambda, due to an
overwhelming background. We also find that, in this mass range, supersymmetric
Higgs boson pairs may be observable at the LHC, but a measurement of the self
coupling will not be possible. For m_H > 140 GeV we examine ZHH and HH nu
bar-nu production at a future e+e- linear collider with center of mass energy
in the range of sqrt{s}=0.5 - 1 TeV, and find that this is likely to be equally
difficult. Combining our results with those of previous literature, which has
demonstrated the capability of hadron and lepton machines to determine \lambda
in either the high or the low mass regions, we establish a very strong
complementarity of these machines.Comment: Revtex, 25 pages, 2 tables, 10 figure
Cardiac involvement in patients recovered from COVID-2019 identified using magnetic resonance imaging
OBJECTIVES This study evaluated cardiac involvement in patients recovered from coronavirus disease-2019 (COVID-19) using cardiac magnetic resonance (CMR).BACKGROUND Myocardial injury caused by COVID-19 was previously reported in hospitalized patients. It is unknown if there is sustained cardiac involvement after patients' recovery from COVID-19.METHODS Twenty-six patients recovered from COVID-19 who reported cardiac symptoms and underwent CMR examinations were retrospectively included. CMR protocols consisted of conventional sequences (cine, T2-weighted imaging, and late gadolinium enhancement [LGE]) and quantitative mapping sequences (T1, T2, and extracellular volume [ECV] mapping). Edema ratio and LGE were assessed in post-COVID-19 patients. Cardiac function, native T1/T2, and ECV were quantitatively evaluated and compared with controls.RESULTS Fifteen patients (58%) had abnormal CMR findings on conventional CMR sequences: myocardial edema was found in 14 (54%) patients and LGE was found in 8 (31%) patients. Decreased right ventricle functional parameters including ejection fraction, cardiac index, and stroke volume/body surface area were found in patients with positive conventional CMR findings. Using quantitative mapping, global native T1, T2, and ECV were all found to be significantly elevated in patients with positive conventional CMR findings, compared with patients without positive findings and controls (median [interquartile range]: native T1 1,271 ms [1,243 to 1,298 ms] vs. 1,237 ms [1,216 to 1,262 ms] vs. 1,224 ms [1,217 to 1,245 ms]; mean +/- SD: T2 42.7 +/- 3.1 ms vs. 38.1 ms +/- 2.4 vs. 39.1 ms +/- 3.1; median [interquartile range]: 28.2% [24.8% to 36.2%] vs. 24.8% [23.1% to 25.4%] vs. 23.7% [22.2% to 25.2%]; p = 0.002; p < 0.001, and p =0.002, respectively).CONCLUSIONS Cardiac involvement was found in a proportion of patients recovered from COVID-19. CMR manifestation included myocardial edema, fibrosis, and impaired right ventricle function. Attention should be paid to the possible myocardial involvement in patients recovered from COVID-19 with cardiac symptoms. (C) 2020 by the American College of Cardiology Foundation.Cardiovascular Aspects of Radiolog
Determining the Higgs Boson Self Coupling at Hadron Colliders
Inclusive Standard Model Higgs boson pair production at hadron colliders has
the capability to determine the Higgs boson self-coupling, lambda. We present a
detailed analysis of the gg\to HH\to (W^+W^-)(W^+W^-)\to
(jjl^\pm\nu)(jj{l'}^\pm\nu) and gg\to HH\to (W^+W^-)(W^+W^-)\to
(jjl^\pm\nu)({l'}^\pm\nu {l''}^\mp\nu) (l, {l'}, {l''}=e, \mu) signal channels,
and the relevant background processes, for the CERN Large Hadron Collider, and
a future Very Large Hadron Collider operating at a center-of-mass energy of 200
TeV. We also derive quantitative sensitivity limits for lambda. We find that it
should be possible at the LHC with design luminosity to establish that the
Standard Model Higgs boson has a non-zero self-coupling and that lambda /
lambda_{SM} can be restricted to a range of 0-3.8 at 95% confidence level (CL)
if its mass is between 150 and 200 GeV. At a 200 TeV collider with an
integrated luminosity of 300 fb^{-1}, lambda can be determined with an accuracy
of 8 - 25% at 95% CL in the same mass range.Comment: 28 pages, Revtex3, 9 figures, 3 table
The Yuan-Tseh Lee Array for Microwave Background Anisotropy
The Yuan-Tseh Lee Array for Microwave Background Anisotropy (AMiBA) is the
first interferometer dedicated to studying the cosmic microwave background
(CMB) radiation at 3mm wavelength. The choice of 3mm was made to minimize the
contributions from foreground synchrotron radiation and Galactic dust emission.
The initial configuration of seven 0.6m telescopes mounted on a 6-m hexapod
platform was dedicated in October 2006 on Mauna Loa, Hawaii. Scientific
operations began with the detection of a number of clusters of galaxies via the
thermal Sunyaev-Zel'dovich effect. We compare our data with Subaru weak lensing
data in order to study the structure of dark matter. We also compare our data
with X-ray data in order to derive the Hubble constant.Comment: accepted for publication in ApJ (13 pages, 7 figures); a version with
high resolution figures available at
http://www.asiaa.sinica.edu.tw/~keiichi/upfiles/AMiBA7/pho_highreso.pd
Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
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