344 research outputs found
In My View
Every successful officer considers his career path as that most appropriate and useful. So it is—for him or her. Certainly the successes of Admiral Stavridis and Captain Hagerott testify to the worth of their credentials to make the arguments in their article [see James Stavridis and Mark Hagerott, “The Heart of an Officer: Joint, Interagency, and International Operations and Navy Career Develop- ment,” in the Spring 2009 issue, pp. 27–41]
In My View
The central thesis of the article entitled “U.S. Policy on Small Arms and Light Weapons,” by Loretta Bondì, which appeared in the Winter 2006 edition of the Naval War College Review, is that the U.S. system of export controls on small arms is as good as any, and better than most other countries, but that American moral authority in this area is undermined by its permitting widespread civilian ownership of firearms
Survey of major trauma centre preparedness for mass casualty incidents in Australia, Canada, England and New Zealand
Background: Mass casualty incidents (MCIs) are increasing. Trauma centres play a key role in MCIs due to their readiness and expansive multidisciplinary expertise for injury management. Previous studies have shown deficiencies in trauma centre disaster preparedness. The aim of this study was to describe the current disaster preparedness of Major Trauma Centres (MTCs) in Australia, Canada, England and New Zealand. Methods: A cross-sectional survey of all (n = 82) MTCs was undertaken. The anonymous survey collected data about disaster preparedness in nine key areas. Respondents were encouraged to consult appropriately at their centre to provide an accurate representation of their centre’s preparedness. Findings: Responses were received from 69 (84%) centres; 61 completed all questions. 91% had a disaster preparedness committee and 80% had an all-hazards emergency plan. 79% had held an MCI drill in the past 2 years. 54% reported a system in place to calculate maximum capacity, but testing of surge capacity was uncommon. 55% reported the presence of stored resources for an MCI and 58% had a database of staff trained in Emergency Management. 74% had a training and education plan available for staff involved in an MCI and a plan for professional debriefing of staff post-MCI, while 62% had a post-disaster employee assistance programme. Most centres had appropriate back-up communication, safety and security plans. Interpretation: The disaster preparedness of MTCs was high for communication, safety and security but there was clear need for improvement in other areas including surge capacity, human resources and post-disaster recovery
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CMOS image sensors for x-ray interferometry
X-ray interferometry (XRI) was first demonstrated in the early 2000’s, and many early mission concepts followed which exploited the significant improvement in spatial resolution that XRI offered. Unfortunately, optical technology was not mature enough to meet the requirements, and the idea remained dormant. ESA’s voyage 2050 programme, in combination with optical and pointing accuracy technology developments, has reignited interest in the concept, but large technological challenges still remain to realise such a groundbreaking telescope. Given the spectral and now spatial requirements of a XRI, the next generation of detector technologies must be developed which can meet those requirements to enable such a telescope. For the proposed ESA THESEUS x-ray astronomy mission, strict requirements on instrument operating temperature (-40°C) have necessitated developments of new detectors technologies, namely CMOS image sensors (CIS). The CEI, in collaboration with Te2v, have designed, manufactured, and characterised a monolithic fully depleted CIS specifically optimised for soft x-ray astronomy. The prototype detector currently meets the THESEUS soft x-ray imager requirements and boasts a near Fano-limited energy resolution of 130eV (@5.9keV) at -40°C. Although the new technology can perform well, the specific detector requirements of XRI need to balance opposing parameters of spatial and energy resolution. This paper will outline the current performance of the CIS221-X for soft x-ray astronomy (as well as other competing technologies) and describe future plans for developing CIS to meet the challenging requirements of XRI
The Kuiper Belt and Other Debris Disks
We discuss the current knowledge of the Solar system, focusing on bodies in
the outer regions, on the information they provide concerning Solar system
formation, and on the possible relationships that may exist between our system
and the debris disks of other stars. Beyond the domains of the Terrestrial and
giant planets, the comets in the Kuiper belt and the Oort cloud preserve some
of our most pristine materials. The Kuiper belt, in particular, is a
collisional dust source and a scientific bridge to the dusty "debris disks"
observed around many nearby main-sequence stars. Study of the Solar system
provides a level of detail that we cannot discern in the distant disks while
observations of the disks may help to set the Solar system in proper context.Comment: 50 pages, 25 Figures. To appear in conference proceedings book
"Astrophysics in the Next Decade
Patient journey mapping to investigate quality and cultural safety in burn care for Aboriginal and Torres Strait Islander children and families - development, application and implications.
Background Quality and safety in Australian healthcare is inequitably distributed, highlighted by gaps in the provision of quality care for Aboriginal and Torres Strait Islander children. Burns have potential for long-term adverse outcomes, and quality care, including culturally safe care, is critical to recovery. This study aimed to develop and apply an Aboriginal Patient Journey Mapping (APJM) tool to investigate the quality of healthcare systems for burn care with Aboriginal and Torres Strait Islander children. Study design Interface research methodology, using biomedical and cultural evidence, informed the modification of an existing APJM tool. The tool was then applied to the journey of one family accessing a paediatric tertiary burn care site. Data were collected through yarning with the family, case note review and clinician interviews. Data were analysed using Emden's core story and thematic analysis methods. Reflexivity informed consideration of the implications of the APJM tool, including its effectiveness and efficiency in eliciting information about quality and cultural safety. Results Through application of a modified APJM tool, gaps in quality care for Aboriginal and Torres Strait Islander children and families were identified at the individual, service and system levels. Engagement in innovative methodology incorporating more than biomedical standards of care, uncovered critical information about the experiences of culturally safe care in complex patient journeys. Conclusion Based on our application of the tool, APJM can identify and evaluate specific aspects of culturally safe care as experienced by Aboriginal and Torres Strait Islander peoples and be used for quality improvement.Sarah Fraser, Tamara Mackean, Julian Grant, Kate Hunter, Courtney Ryder, Janet Kelly, Andrew J. A. Holland, Bronwyn Griffin, Kathleen Clapham, Warwick J. Teague, Anne Darton, and Rebecca Q. Iver
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus (MRSA) is a major hospital- and communityacquired pathogen, but the mechanisms underlying host-defense to MRSA remain poorly
understood. Here, we investigated the role of IL-21 in this process. When administered intratracheally into wild-type mice, IL-21 induced granzymes and augmented clearance of pulmonary
MRSA but not when neutrophils were depleted or a granzyme B inhibitor was added.
Correspondingly, IL-21 induced MRSA killing by human peripheral blood neutrophils.
Unexpectedly, however, basal MRSA clearance was also enhanced when IL-21 signaling was
blocked, both in Il21r KO mice and in wild-type mice injected with IL-21R-Fc fusion-protein. This
correlated with increased type I interferon and an IFN-related gene signature, and indeed antiIFNAR1 treatment diminished MRSA clearance in these animals. Moreover, we found that IFNb
induced granzyme B and promoted MRSA clearance in a granzyme B-dependent fashion. These
results reveal an interplay between IL-21 and type I IFN in the innate immune response to MRS
Interferometry with independent Bose-Einstein ondensates: parity as an EPR/Bell quantum variable
When independent Bose-Einstein condensates (BEC), described quantum
mechanically by Fock (number) states, are sent into interferometers, the
measurement of the output port at which the particles are detected provides a
binary measurement, with two possible results . With two interferometers
and two BEC's, the parity (product of all results obtained at each
interferometer) has all the features of an Einstein-Podolsky-Rosen quantity,
with perfect correlations predicted by quantum mechanics when the settings
(phase shifts of the interferometers) are the same. When they are different,
significant violations of Bell inequalities are obtained. These violations do
not tend to zero when the number of particles increases, and can therefore
be obtained with arbitrarily large systems, but a condition is that all
particles should be detected. We discuss the general experimental requirements
for observing such effects, the necessary detection of all particles in
correlation, the role of the pixels of the CCD detectors, and that of the
alignments of the interferometers in terms of matching of the wave fronts of
the sources in the detection regions. Another scheme involving three
interferometers and three BEC's is discussed; it leads to Greenberger Horne
Zeilinger (GHZ) sign contradictions, as in the usual GHZ case with three
particles, but for an arbitrarily large number of them. Finally,
generalizations of the Hardy impossibilities to an arbitrarily large number of
particles are introduced. BEC's provide a large versality for observing
violations of local realism in a variety of experimental arrangements.Comment: appendix adde
Comparison of the physical and geotechnical properties of gas-hydrate-bearing sediments from offshore India and other gas-hydrate-reservoir systems
This paper is not subject to U.S. copyright. The definitive version was published in Marine and Petroleum Geology 58A (2014): 139-167, doi:10.1016/j.marpetgeo.2014.07.024.The sediment characteristics of hydrate-bearing reservoirs profoundly affect the formation, distribution, and morphology of gas hydrate. The presence and type of gas, porewater chemistry, fluid migration, and subbottom temperature may govern the hydrate formation process, but it is the host sediment that commonly dictates final hydrate habit, and whether hydrate may be economically developed.
In this paper, the physical properties of hydrate-bearing regions offshore eastern India (Krishna-Godavari and Mahanadi Basins) and the Andaman Islands, determined from Expedition NGHP-01 cores, are compared to each other, well logs, and published results of other hydrate reservoirs. Properties from the hydrate-free Kerala-Konkan basin off the west coast of India are also presented. Coarser-grained reservoirs (permafrost-related and marine) may contain high gas-hydrate-pore saturations, while finer-grained reservoirs may contain low-saturation disseminated or more complex gas-hydrates, including nodules, layers, and high-angle planar and rotational veins. However, even in these fine-grained sediments, gas hydrate preferentially forms in coarser sediment or fractures, when present. The presence of hydrate in conjunction with other geologic processes may be responsible for sediment porosity being nearly uniform for almost 500 m off the Andaman Islands.
Properties of individual NGHP-01 wells and regional trends are discussed in detail. However, comparison of marine and permafrost-related Arctic reservoirs provides insight into the inter-relationships and common traits between physical properties and the morphology of gas-hydrate reservoirs regardless of location. Extrapolation of properties from one location to another also enhances our understanding of gas-hydrate reservoir systems. Grain size and porosity effects on permeability are critical, both locally to trap gas and regionally to provide fluid flow to hydrate reservoirs. Index properties corroborate more advanced consolidation and triaxial strength test results and can be used for predicting behavior in other NGHP-01 regions. Pseudo-overconsolidation is present near the seafloor and is underlain by underconsolidation at depth at some NGHP-01 locations.This work was supported by the Coastal and Marine Geology, and Energy Programs of the U.S. Geological Survey. Partial support for this research was provided by Interagency Agreement DE-FE0002911 between the USGS Gas Hydrates Project and the U.S. Department of Energy's Methane Hydrates R&D Program
E-retailing ethics in Egypt and its effect on customer repurchase intention
The theoretical understanding of online shopping behaviour has received much attention. Less focus has been given to the formation of the ethical issues that result from online shopper interactions with e-retailers. The vast majority of earlier research on this area is conceptual in nature and limited in scope by focusing on consumers’ privacy issues. Therefore, the purpose of this paper is to propose a theoretical model explaining what factors contribute to online retailing ethics and its effect on customer repurchase intention. The data were analysed using variance-based structural equation modelling, employing partial least squares regression. Findings indicate that the five factors of the online retailing ethics (security, privacy, non- deception, fulfilment/reliability, and corporate social responsibility) are strongly predictive of online consumers’ repurchase intention. The results offer important implications for e-retailers and are likely to stimulate further research in the area of e-ethics from the consumers’ perspective
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