Adhesion of Different Resin Cements to Zirconia: Effect of Incremental versus Bulk Build Up, Use of Mould and Ageing.

Bonding to zirconia presents a great challenge, as the clinical guidelines for predictable adhesion are not sufficiently validated. The aim of this study was to assess the influence of various bonding methodologies of various resin cements on zirconia, using different aging protocols. Manufactured zirconia specimens (N = 300 and n = 20 per group) were randomly assigned to three luting protocols: 1-in mould incremental build up; 2-in mould incremental build up with mould removal; 3-in mould non-incremental bulk build up. Five dual, photo- and chemical-cure resin cements were used, namely, Variolink Esthetic (Ivoclar), Tetric (Ivoclar), Panavia (Kuraray), TheraCem (Bisco), and RelyX UniCem (3M ESPE), and were applied on primed zirconia using photopolymerization protocols. Thereafter, the specimens were subjected to the following three ageing methods: 1-dry; 2-thermocycling (×5000; 5-55 °C); 3-3-6 months of water storage. Using a universal testing machine, the specimens were loaded under shear, at 1 mm/min crosshead speed. An analysis of the data was performed using three-way ANOVA and the Bonferroni method. The moulding type, ageing and luting cement significantly affected the results (p < 0.05). Among all the protocols under dry conditions, TheraCem (16 ± 3; 11 ± 1; 16 ± 3) showed the best bond strength, while, after thermocycling, TheraCem (7 ± 2) and Tetric (7 ± 2) performed the best with Protocol 1. In Protocol 2, RelyX (7 ± 3) presented the highest result, followed by TheraCem (5 ± 3) and Tetric (5 ± 1) (p < 0.05). Using Protocol 3, RelyX (10 ± 6) showed the highest result, followed by TheraCem (7 ± 2) and Panavia21 (7 ± 2) (p < 0.05). Six months after water storage, TheraCem presented the highest result (10 ± 2) in Protocol 1, while, in Protocols 2 and 3, Tetric (10 ± 2; 15 ± 5) presented the highest result, followed by TheraCem (6 ± 2; 8 ± 3). Adhesion tests using the incremental or bulk method, using moulds, showed the highest results, but removing the mould, and the subsequent ageing, caused a decrease in the adhesion of the resin cements tested on zirconia, probably due to water absorption, with the exclusion of Tetric

Assessing masticatory performance with a colour-mixing ability test using smartphone camera images

BACKGROUND Colour-mixing ability tests are frequently used to assess masticatory performance, but the image acquisition process may be cumbersome and technique sensitive. OBJECTIVES To evaluate the reliability of smartphone camera images in assessing masticatory performance using a colour-mixing ability test. METHODS Participants were recruited into three groups of dental state (n = 20 each): fully dentate, removable partial denture wearers and complete denture wearers. After performing a colour-mixing ability test, images of the gum specimens (Hue-Check Gum©) were captured with two smartphones and compared with the images obtained from a flatbed scanner by two examiners. The images were analysed with a subjective- (SA) and an opto-electronical assessment (VoH). Inter- and intra-rater reliability were tested. ANOVA models with repeated measures were used for statistical analysis (⍺ = .05). RESULTS All three image acquisition techniques were able to distinguish masticatory performance between different dental states. For SA, inter-rater reliability was fair to substantial and intra-rater reliability was substantial to almost perfect. For VoH, inter-rater reliability with the smartphones was at times different between two examiners, but the intra-rater assessment was reliable. The opto-electronic analysis with smartphone images underestimated the masticatory performance significantly when compared to the flatbed scanner analysis. Seven-day ageing of the specimens did not significantly affect the results. CONCLUSIONS The assessment of masticatory performance with the Hue-Check Gum© is a reliable method. The use of smartphones may occasionally underestimate masticatory performance; image acquisition with a flatbed scanner remains the gold standard. A centralised analysis of the photographed wafer may foster the reliability of the diagnosis

Nordic Concrete Research workshop: “Accelerated freeze- thaw testing of concrete”, Lyngby, 20th April 2022

A one-day Nordic Concrete Research workshop on "Accelerated freeze-thaw testing of concrete" attracted approx. 30 participants. The workshop included presentations on various aspects, such as observed frost damage in the field and the importance of the temperature curve during testing as well as other interactions with the surroundings of the concrete. The workshop also included examples of recent research, which can improve our knowledge about the frost damage mechanism and therefore provide input to improving the standardised test methods. The present paper is a summary of the nine presentations and the discussion arising from the presentations

A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis.

New regenerative materials and approaches need to be assessed through reliable and comparable methods for rapid translation to the clinic. There is a considerable need for proven in vitro assays that are able to reduce the burden on animal testing, by allowing assessment of biomaterial utility predictive of the results currently obtained through in vivo studies. The purpose of this multicentre review was to investigate the correlation between existing in vitro results with in vivo outcomes observed for a range of biomaterials. Members from the European consortium BioDesign, comprising 8 universities in a European multicentre study, provided data from 36 in vivo studies and 47 in vitro assays testing 93 different biomaterials. The outcomes of the in vitro and in vivo experiments were scored according to commonly recognised measures of success relevant to each experiment. The correlation of in vitro with in vivo scores for each assay alone and in combination was assessed. A surprisingly poor correlation between in vitro and in vivo assessments of biomaterials was revealed indicating a clear need for further development of relevant in vitro assays. There was no significant overall correlation between in vitro and in vivo outcome. The mean in vitro scores revealed a trend of covariance to in vivo score with 58 %. The inadequacies of the current in vitro assessments highlighted here further stress the need for the development of novel approaches to in vitro biomaterial testing and validated pre-clinical pipelines

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE