Expected functions of an effective child justice system administration? A framework developed through a qualitative study in Turkey

Research problem / aim: Turkey initiated its first specialized child court in 1987, but the most visible improvements towards establishing child-specific judicial procedures were only achieved in 2005, when the Child Protection Law (CPL) became effective. This Law required the involvement of several agencies in both providing protection for children and adjudicating them when they were involved in delinquency. After this Law was enacted several comprehensive projects were carried out, different institutions were established, and different legal and policy changes took place to maintain the effective administration of child justice procedures. Yet, practical observations of these different stake holders indicated that a useful, productive, and cohesive system in coordinating these various agencies involved in the child justice system procedural processes was not fully achieved as of 2016. The primary objective of this study was to develop a framework on how an effective child justice administration system should be established and what kinds of functions it should carry out in Turkey.Method: This study, first of all, provides an analysis of the existing practices and procedures of the various agencies involved in administering child justice procedures through a series of systematic observations, as well as focus group and in-depth interviews with key informants.Findings: The findings of this study yielded propositions on the general principles, functions, and the bureaucratic nature of such system that can increase the overall effectiveness of the outcomes of the juvenile justice processes.Conclusion: This study concludes with a discussion of how the study findings should be utilized in both the Turkish and international contexts

Ridge Augmentation Techniques in Preprosthetic Implant Surgery

Rehabilitation of missing teeth with dental implant-supported restorations has become a predictable treatment option in dentistry. The stability of hard and soft tissues around the implant is fundamental for long-term success. However, due to factors such as trauma, oncologic diseases, and missing teeth, vertical and horizontal bone loss is expected, and the available bone may not be suitable for optimum implant placement. Ridge augmentation procedures are applied to increase in the volume of the deficient sites for implant treatment. Autogenous block bone augmentation and guided bone regeneration (GBR) are two surgical approaches for implant placement. Autogenous bone is widely used for augmentations because of its osteogenic potential. A myriad of biomaterials, including xenografts, allografts, alloplasts, and composite grafts, are available for GBR. The aim of this chapter is to provide a brief summary of these methods and to discuss the advantages and pitfalls of ridge augmentation techniques

Hard Tissue Regeneration Treatment Protocols in Contemporary Oral Surgery

Dental implant placement is one of the most reliable and predictable treatment choices in modern oral surgery. It requires available bone volume to resist the force during loading. There are many ways to regenerate the bone to place the implants with the desired dimensions. Guided bone regeneration, socket grafting, allograft bone block grafting, and intra- and extraoral autogenous bone block grafting are the most popular treatment approaches to reconstruct hard tissues. Autogenous bone graft is still considered the gold standard for the reconstruction of hard tissues. In addition, there are many scaffold biomaterials available that are used as templates for new bone formation. These biomaterials are helpful to not only eliminate the usage of autogenous bone grafts but also decrease patient morbidity. Another advantage of biomaterial usage in tissue regeneration is to reduce the learning curve of treatments by facilitating operative approaches. The aim of this chapter is to evaluate contemporary biomaterials that are used to reconstruct hard tissue defects in oral surgery

Platelet Rich Fibrin (PRF) Application in Oral Surgery

Platelet rich fibrin (PRF) is an autologous biological product which becomes popular day by day and available in a wide variety of fields in medicine. Platelet concentrates which are introduced at the early 90s have evolved over the years. The use such autologous materials have become trendy in recent years to encounter demanding expectations of patients, improve treatment success and maximize patient comfort. Despite its increasing use in dentistry and oral surgery, the most indications and effects are still being discussed. PRF is easily accepted by patients because of its low cost, easy to receive, low donor morbidity, low postoperative complication and infection rate. This biomaterial may be a solution for patients who have strong negative beliefs about the use of allografts and xenografts or who are afraid of complications during the grafting procedure. The objectives of these technologies are to use their synergistic effect to improve the hard and soft tissue regeneration. PRF in oral surgery are used for alveolar bone reconstruction, dental implant surgery, sinus augmentation, socket preservation, osteonecrosis, oroantral fistula closure, struggling with oral ulcers, preventing swelling and edema constitution. This chapter aims to review the clinical applications of platelets in oral surgery and the role of molecular components in tissue healing

Treatment of Oral Fistulas

The term “fistula” can be defined as an improper connection between different body compartments. It can occur in different parts of the body. Although, fistulae mostly develop due to untreated chronic infections, traumatic injuries and congenital deformities, specific infections or diseases, and post-surgical healing abnormalities can also cause fistula formation. Although, there is a general classification system made by the World Health Organization to identify fistulae, specifically, in this chapter oral fistulae are divided into four different categories, namely dentoalveolar, oroantral, oronasal and orocutaneous fistulae. The diagnosis and the treatment protocols for oral fistulas are described using this specific classification and with additional new techniques introduced for the correction of the lesions. Conventional surgical methods also are summarized. The importance of the radiological examination is emphasized and the practitioners are informed of possible complications

Leptomeningeal metastasis in primary uterine cervical cancer: a rare case and review of the literature

Objectives. Leptomeningeal metastasis (LM) of primary uterine cervical cancer is rare and treatment options are limited. In this case report and literature review, we aimed to present a patient with cervical cancer with LM and discuss previously reported cases in the literature.  Case presentation. Our case was a 58-year-old patient who was initially diagnosed with metastatic primary uterine cervical cancer and treated with chemotherapy and chemoradiotherapy. During follow-up, she developed neurological symptoms, and LM was detected in the craniospinal regions. Cerebrospinal fluid cytology examination has confirmed metastatic disease. The patient was treated with concurrent intrathecal methotrexate and whole-brain radiotherapy (WBRT). A good clinical and cytological response was obtained. However, while intrathecal methotrexate was being continued after WBRT, she succumbed to hematological toxicity before the radiological response could be evaluated. Conclusions. LM is an extremely rare and catastrophic distant spread pattern in patients with cervical cancer. In the literature, a total of 26 patients were reported up to date. Median survival after detection of LM was nine weeks, including our case. Multimodal treatment combinations such as systemic and intrathecal chemotherapy and radiotherapy (RT) were used. However, most of these reports did not have detailed information about toxicity. Despite the combined use of aggressive treatment modalities, patients have limited survival and very high risks of hematologic toxicity. Concurrent use of intrathecal chemotherapy and radiotherapy should be avoided due to increased risk of morbidity

Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children

Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or RNASEL in five unrelated children with MIS-C. The cytosolic double-stranded RNA (dsRNA)-sensing OAS1 and OAS2 generate 2'-5'-linked oligoadenylates (2-5A) that activate the single-stranded RNA-degrading ribonuclease L (RNase L). Monocytic cell lines and primary myeloid cells with OAS1, OAS2, or RNase L deficiencies produce excessive amounts of inflammatory cytokines upon dsRNA or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulation. Exogenous 2-5A suppresses cytokine production in OAS1-deficient but not RNase L-deficient cells. Cytokine production in RNase L-deficient cells is impaired by MDA5 or RIG-I deficiency and abolished by mitochondrial antiviral-signaling protein (MAVS) deficiency. Recessive OAS-RNase L deficiencies in these patients unleash the production of SARS-CoV-2-triggered, MAVS-mediated inflammatory cytokines by mononuclear phagocytes, thereby underlying MIS-C

East meets west: when the Islamic and Gregorian calendars coincide

Recent research has documented that at the time of religious celebrations in Muslim countries, such as Ramadan, there is a “festival” effect in share returns. In the Gregorian calendar, December is also a time of celebration and festivities which may be associated with patterns in the behaviour of security prices. Further, the first month of the year in the Islamic calendar, Muharram, is a time of sadness and mourning for some believers, and there may be an effect when the Islamic first month of the year overlaps with the first month of the Gregorian year - January. Over a 33-year cycle, each Islamic month falls in a Gregorian month for about 5–6 consecutive years; when this happens, an Islamic (Eastern) calendar effect may interact with a Gregorian (Western) calendar effect. The current paper addresses this issue by examining the behaviour of share returns and volatility for individual companies listed in Muslim countries’ stock exchanges when the two calendars coincide for: (i) religious festival effects; (ii) first-month-of-the-year effects; and (iii) the two most common effects reported in the Islamic and Gregorian calendars (Ramadan and January). The results show that the Western and Eastern effects interact more prominently in larger companies and in larger or more developed markets

Cement selection for implant-supported crowns fabricated with different luting space settings.

Purpose: To measure and compare the retentive strength of cements specifically formulated for luting restorations onto implant abutments and to investigate the effect of varying cement gap on retention strength of implant-supported crowns. Materials and Methods: Standard titanium abutments were scanned by means of a 3D digital laser scanner. One hundred and sixty standard metal copings were designed by a Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) system with two cement gap values (20 and 40 m). The copings were cemented to the abutments using the following eight cements with one being the control, zinc oxide temporary cement, while the other seven were specifically formulated implant cements (n = 10): Premier Implant Cement, ImProv, Multilink Implant, EsTemp Implant, Cem-Implant, ImplaTemp, MIS Crown Set, and TempBond NE. The specimens were placed in 100% humidity for 24 hours, and subjected to a pull-out test using a universal testing machine at a 0.5 mm/min crosshead speed. The test results were analyzed with two-way ANOVA, one-way ANOVA, post hoc Tamhane' s T2, and student's t-tests at a significance level of 0.05. Results: Statistical analysis revealed significant differences in retention strength across the cement groups (p 0.05). Conclusions: Resin cements specifically formulated for implant-supported restorations demonstrated significant differences in retention strength. The ranking of cements presented in the study is meant to be an arbitrary guide for the clinician in deciding the appropriate cement selection for CAD/CAM-fabricated metal copings onto implant abutments with different luting space settings