642 research outputs found
Spinor dynamics in an antiferromagnetic spin-1 thermal Bose gas
We present experimental observations of coherent spin-population oscillations
in a cold thermal, Bose gas of spin-1 sodium-23 atoms. The population
oscillations in a multi-spatial-mode thermal gas have the same behavior as
those observed in a single-spatial-mode antiferromagnetic spinor Bose Einstein
condensate. We demonstrate this by showing that the two situations are
described by the same dynamical equations, with a factor of two change in the
spin-dependent interaction coefficient, which results from the change to
particles with distinguishable momentum states in the thermal gas. We compare
this theory to the measured spin population evolution after times up to a few
hundreds of ms, finding quantitative agreement with the amplitude and period.
We also measure the damping time of the oscillations as a function of magnetic
field.Comment: 5 pages, 3 figure
In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation
Drug release from mesoporous silica systems has been widely investigated in vitro using USP Type II (paddle) dissolution apparatus. However, it is not clear if the observed enhanced in vitro dissolution can forecast drug bioavailability in vivo. In this study, the ability of different in vitro dissolution models to predict in vivo oral bioavailability in a pig model was examined. The fenofibrate-loaded mesoporous silica formulation was compared directly to a commercial reference product, Lipantil Supra®. Three in vitro dissolution methods were considered; USP Type II (paddle) apparatus, USP Type IV (flow-through cell) apparatus and a USP IV Transfer model (incorporating a SGF to FaSSIF-V2 media transfer). In silico modelling, using a physiologically based pharmacokinetic modelling and simulation software package (Gastroplus™), to generate in vitro/in vivo relationships was also investigated. The study demonstrates that the in vitro dissolution performance of a mesoporous silica formulation varies depending on the dissolution apparatus utilised and experimental design. The findings show that the USP IV transfer model was the best predictor of in vivo bioavailability. The USP Type II (paddle) apparatus was not effective at forecasting in vivo behaviour. This observation is likely due to hydrodynamic differences between the two apparatus and the ability of the transfer model to better simulate gastrointestinal transit. The transfer model is advantageous in forecasting in vivo behaviour for formulations which promote drug supersaturation and as a result are prone to precipitation to a more energetically favourable, less soluble form. The USP IV transfer model could prove useful in future mesoporous silica formulation development. In silico modelling has the potential to assist in this process. However, further investigation is required to overcome the limitations of the model for solubility enhancing formulations
Patient information leaflets (PILs) for UK randomised controlled trials : a feasibility study exploring whether they contain information to support decision making about trial participation
Peer reviewedPublisher PD
The Most Metal-Poor Stars. II. Chemical Abundances of 190 Metal-Poor Stars Including 10 New Stars With [Fe/H] < -3.5
We present a homogeneous chemical abundance analysis of 16 elements in 190
metal-poor Galactic halo stars (38 program and 152 literature objects). The
sample includes 171 stars with [Fe/H] < -2.5, of which 86 are extremely metal
poor, [Fe/H] < -3.0. Our program stars include ten new objects with [Fe/H] <
-3.5. We identify a sample of "normal" metal-poor stars and measure the trends
between [X/Fe] and [Fe/H], as well as the dispersion about the mean trend for
this sample. Using this mean trend, we identify objects that are chemically
peculiar relative to "normal" stars at the same metallicity. These chemically
unusual stars include CEMP-no objects, one star with high [Si/Fe], another with
high [Ba/Sr], and one with unusually low [X/Fe] for all elements heavier than
Na. The Sr and Ba abundances indicate that there may be two nucleosynthetic
processes at lowest metallicity that are distinct from the main r-process.
Finally, for many elements, we find a significant trend between [X/Fe] versus
Teff which likely reflects non-LTE and/or 3D effects. Such trends demonstrate
that care must be exercised when using abundance measurements in metal-poor
stars to constrain chemical evolution and/or nucleosynthesis predictions.Comment: Accepted for publication in Ap
Photometric Classification of 2315 Pan-STARRS1 Supernovae with Superphot
The classification of supernovae (SNe) and its impact on our understanding of explosion physics and progenitors have traditionally been based on the presence or absence of certain spectral features. However, current and upcoming wide-field time-domain surveys have increased the transient discovery rate far beyond our capacity to obtain even a single spectrum of each new event. We must therefore rely heavily on photometric classification— connecting SN light curves back to their spectroscopically defined classes. Here, we present Superphot, an opensource Python implementation of the machine-learning classification algorithm of Villar et al., and apply it to 2315 previously unclassified transients from the Pan-STARRS1 Medium Deep Survey for which we obtained spectroscopic host-galaxy redshifts. Our classifier achieves an overall accuracy of 82%, with completenesses and purities of >80% for the best classes (SNe Ia and superluminous SNe). For the worst performing SN class (SNe Ibc), the completeness and purity fall to 37% and 21%, respectively. Our classifier provides 1257 newly classified SNe Ia, 521 SNe II, 298 SNe Ibc, 181 SNe IIn, and 58 SLSNe. These are among the largest uniformly observed samples of SNe available in the literature and will enable a wide range of statistical studies of each class
Discovery and Follow-up Observations of the Young Type Ia Supernova 2016coj
The Type~Ia supernova (SN~Ia) 2016coj in NGC 4125 (redshift ) was
discovered by the Lick Observatory Supernova Search 4.9 days after the fitted
first-light time (FFLT; 11.1 days before -band maximum). Our first detection
(pre-discovery) is merely day after the FFLT, making SN 2016coj one
of the earliest known detections of a SN Ia. A spectrum was taken only 3.7 hr
after discovery (5.0 days after the FFLT) and classified as a normal SN Ia. We
performed high-quality photometry, low- and high-resolution spectroscopy, and
spectropolarimetry, finding that SN 2016coj is a spectroscopically normal SN
Ia, but with a high velocity of \ion{Si}{2} 6355 (\,\kms\
around peak brightness). The \ion{Si}{2} 6355 velocity evolution can
be well fit by a broken-power-law function for up to a month after the FFLT. SN
2016coj has a normal peak luminosity ( mag), and it
reaches a -band maximum \about16.0~d after the FFLT. We estimate there to be
low host-galaxy extinction based on the absence of Na~I~D absorption lines in
our low- and high-resolution spectra. The spectropolarimetric data exhibit weak
polarization in the continuum, but the \ion{Si}{2} line polarization is quite
strong () at peak brightness.Comment: Submitte
The Vehicle, Fall 1997
Vol 39, No. 1
Table of Contents
dancingDavid Moutraypage 1
UntitledMaria Nelsonpage 2
Braver Shades of FireEric Footepage 3
A CoverAmanda Davispage 4
Soup KitchenBlanca Delgadopage 5
Shades of TruthChad P. Elliotpage 5
UntitledNicole Guzaldopage 6
The FogJoe Howardpage 7
Horse-spitMichael Kawapage 8
A Red Coffee MugJoe Howardpage 9
Morning AfterRafael Gomezpage 10
Watching BoysKim Hunterpage 11
UntitledNatalie Macellaiopage 12
Synesthesia in Mood of JulyDoug Strahanpage 13
picasso heartRyan Reevespage 14
Spanish ClassBlanca Delgadopage 15
UntitledElizabeth Hollandpage 16
ApocalypseBlanca Delgadopage 17
CHRISTIANITY IN CALIFORNIAMichael H. Lakepage 18
To Love a MannequinSylvia L. Whippopage 19
UntitledGwen Griffinpage 20
cardboard wolverinesRyan Reevespage 21
NeilKelly Flohrpage 22-25https://thekeep.eiu.edu/vehicle/1068/thumbnail.jp
Herschel-ATLAS: VISTA VIKING near-IR counterparts in the Phase 1 GAMA 9h data
We identify near-infrared Ks band counterparts to Herschel-ATLAS sub-mm
sources, using a preliminary object catalogue from the VISTA VIKING survey. The
sub-mm sources are selected from the H-ATLAS Phase 1 catalogue of the GAMA 9h
field, which includes all objects detected at 250, 350 or 500 um with the SPIRE
instrument. We apply and discuss a likelihood ratio (LR) method for VIKING
candidates within a search radius of 10" of the 22,000 SPIRE sources with a 5
sigma detection at 250 um. We find that 11,294(51%) of the SPIRE sources have a
best VIKING counterpart with a reliability , and the false
identification rate of these is estimated to be 4.2%. We expect to miss ~5% of
true VIKING counterparts. There is evidence from Z-J and J-Ks colours that the
reliable counterparts to SPIRE galaxies are marginally redder than the field
population. We obtain photometric redshifts for ~68% of all (non-stellar)
VIKING candidates with a median redshift of 0.405. Comparing to the results of
the optical identifications supplied with the Phase I catalogue, we find that
the use of medium-deep near-infrared data improves the identification rate of
reliable counterparts from 36% to 51%.Comment: 20 pages, 20 figures, 3 tables, accepted by MNRA
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