53 research outputs found
Structural Geology and the Seismotectonics of the 2004 Great Sumatran Earthquake
The paper sets out a method for structural analysis of seismotectonic data using centroid moment tensors and associated hypocenters from the Global Centroid Moment Tensor project, here illustrated for aftershocks from the 2004 great Sumatran earthquake. We show that the Sumatran segments of the megathrust were subject to compression in a direction near to orthogonal with the margin trend, consistent with the effect of relative movement of the adjacent tectonic plates. In contrast, the crust above the Andaman Sea segments was subject to margin-orthogonal extension, consistent with motion toward the gravitational potential well accumulated due to prior lateral (westward) rollback of the subducting edge of the northward moving Indian plate. Since this potential well is largely defined by topography, this episode of margin-orthogonal extension is at least in part “gravity driven.” It did not last long. Within 15 months, an earthquake cluster across an Andaman Sea spreading segment showed a return to kinematics driven by relative plate motion. The transition can be explained if fluid activity temporarily reduced basal friction (or effective stress) but then led to healing so that the megathrust once again began to develop friction-locked segments. The influence of slab rollback is in developing a gravitational potential well facing the megathrust, hence drawing the overriding crust toward it in the immediate postrupture phase while the megathrust is in a weakened state. Plate tectonics dominates during interseismic gaps, once the megathrust heals, and regains frictional resistance.y. The
authors acknowledge funding support
from the Australian Research Council:
Discovery Project DP120103554 “A unified
model for the closure dynamics of
ancient Tethys constrained by geodesy,
structural geology, argon geochronology
and tectonic reconstruction” and
Linkage Project LP130100134 “Where to
find giant porphyry and epithermal gold
and copper deposits.” The research was
also supported by the “Satellites,
Seismometers and Mass Spectrometers”
initiative within the Research School of
Earth Sciences at ANU. Bob Engdahl is
thanked for his support during earlier
versions and for providing data
40Ar/39Ar thermochronology in the ios basement terrane resolves the tectonic significance of the south cyclades shear zone
We conducted 39Ar diffusion experiments using potassium feldspar from the South Cyclades Shear
Zone on Ios, in the Cyclades, Aegean Sea, Greece. Irradiated samples were step-heated in an ultra-high-vacuum
resistance furnace attached to a mass spectrometer, thus also allowing 40Ar/39Ar geochronology. Conjoint
inversion of these datasets allowed estimation of the relevant diffusion parameters, which were then used to
forward model the effect of arbitrary temperature–time histories. Simulations used Monte Carlo methods to
improve approximations to the observed age spectra. Two periods of rapid cooling could be inferred. The
South Cyclades Shear Zone commenced operation during or shortly after the Eocene–Oligocene transition. Episodes of south-directed movement continued into Early Miocene time, however, with the footwall still hot
enough to cause biotite ± garnet metamorphic mineral growth at the base of the overlying, already substantially
exhumed, eclogite–blueschist unit. Since its footwall continued to cool, the South Cyclades Shear Zone was an
extensional shear zone during both episodes of its operation.Support from an Australian
Research Council Discovery Project, DP12010187
Klondike-Arabia Mountain Local Historic District
Prepared by the Spring 2016 Preservation Planning Class. The proposed Klondike-Arabia Mountain Local Historic District encompasses not just the mountain, but many unique natural and historic resources that are virtually non-existent anywhere else in DeKalb County. The Guidelines are designed to assist the Historic Preservation Commission and property owners on the treatment of historic properties within the district, and based on the Secretary of the Interior\u27s Standards for the Treatment of Historic Propertieshttps://scholarworks.gsu.edu/history_heritagepreservation/1021/thumbnail.jp
Central of Georgia Depot
This interpretive plan gives a brief and condensed history of the central of Georgia Depot. Alongside a history of the depot, this resource provides potential interpretive themes for the historic site to pursue in future programs. The resource also contains reproductions of many historic photographs, as well as survey information regarding the depot\u27s events and programming.https://scholarworks.gsu.edu/history_heritagepreservation/1017/thumbnail.jp
Mesozoic Paleo-Pacific Subduction Beneath SW Borneo: U-Pb Geochronology of the Schwaner Granitoids and the Pinoh Metamorphic Group
The Schwaner Mountains in southwestern Borneo form a large igneous province with a complex magmatic history and poorly known tectonic history. Previously it was known that Cretaceous granitoids intruded metamorphic rocks of the Pinoh Metamorphic Group assumed to be of Paleozoic age. Jurassic granitoids had been reported from the southern Schwaner Mountains. Most ages were based on K-Ar dating. We present new geochemistry, zircon U-Pb and 40Ar/39Ar age data from igneous and metamorphic rocks from the Schwaner Mountains to investigate their tectono-magmatic histories. We subdivide the Schwaner Mountains into three different zones which record rifting, subduction-related and post-collisional magmatism. The Northwest Schwaner Zone (NWSZ) is part of the West Borneo Block which in the Triassic was within the Sundaland margin. It records Triassic to Jurassic magmatism during early Paleo-Pacific subduction. In contrast, the North Schwaner Zone (NSZ) and South Schwaner Zone (SSZ) are part of the SW Borneo (Banda) Block that separated from NW Australia in the Jurassic. Jurassic granitoids in the SSZ are within-plate (A-type) granites interpreted to have formed during rifting. The SW Borneo (Banda) Block collided with eastern Sundaland at c. 135 Ma. Following this, large I-type granitoid plutons and arc volcanics formed in the NWSZ and NSZ between c. 90 and 132 Ma, associated with Cretaceous Paleo-Pacific subduction. The largest intrusion is the c. 110 to 120 Ma Sepauk Tonalite. After collision of the East Java-West Sulawesi (Argo) Block, subduction ceased and post-collisional magmatism produced the c. 78 to 85 Ma Sukadana Granite and the A-type 72 Ma Sangiyang Granite in the SSZ. Rocks of the Pinoh Metamorphic Group mainly exposed in the NSZ, previously assumed to represent Paleozoic basement, contain abundant Early Cretaceous (110 to 135 Ma) zircons. They are interpreted as volcaniclastic sediments that formed contemporaneously with subduction-related volcanic rocks of the NSZ subsequently metamorphosed during intrusion of Cretaceous granitoids. There are no igneous rocks older than Cretaceous in the NSZ and older than Jurassic in the SSZ and there is no evidence for a continuation of a Triassic volcanic arc crossing Borneo from Sundaland to the east.This project was funded by the SE Asia Research Group of Royal
Holloway University of London, which is supported by a
consortium of oil companies
Bacterial Endophytes Enhance Competition by Invasive Plants
Premise of the study: Invasive plants can alter soil microbial communities and profoundly alter ecosystem processes. In the invasive grass Sorghum halepense, these disruptions are consequences of rhizome-associated bacterial endophytes. We describe the effects of N2-fixing bacterial strains from S. halepense (Rout and Chrzanowski, 2009) on plant growth and show that bacteria interact with the plant to alter soil nutrient cycles, enabling persistence of the invasive. Methods: We assessed fluxes in soil nutrients for ~4 yr across a site invaded by S. halepense. We assayed the N2-fixing bacteria in vitro for phosphate solubilization, iron chelation, and production of the plant-growth hormone indole-3-acetic acid (IAA). We assessed the plant’s ability to recruit bacterial partners from substrates and vertically transmit endophytes to seeds and used an antibiotic approach to inhibit bacterial activity in planta and assess microbial contributions to plant growth. Key results: We found persistent alterations to eight biogeochemical cycles (including nitrogen, phosphorus, and iron) in soils invaded by S. halepense. In this context, three bacterial isolates solubilized phosphate, and all produced iron siderophores and IAA in vitro. In growth chamber experiments, bacteria were transmitted vertically, and molecular analysis of bacterial community fingerprints from rhizomes indicated that endophytes are also horizontally recruited. Inhibiting bacterial activity with antibiotics resulted in significant declines in plant growth rate and biomass, with pronounced rhizome reductions. Conclusions: This work suggests a major role of endophytes on growth and resource allocation of an invasive plant. Indeed, bacterial isolate physiology is correlated with invader effects on biogeochemical cycles of nitrogen, phosphate, and iron
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development
Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic regulator SMCHD1 mapping to the extended ATPase domain of the encoded protein cause BAMS in all 14 cases studied. All mutations were de novo where parental DNA was available. Biochemical tests and in vivo assays in Xenopus laevis embryos suggest that these mutations may behave as gain-of-function alleles. This finding is in contrast to the loss-of-function mutations in SMCHD1 that have been associated with facioscapulohumeral muscular dystrophy (FSHD) type 2. Our results establish SMCHD1 as a key player in nasal development and provide biochemical insight into its enzymatic function that may be exploited for development of therapeutics for FSHD
Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity
Polycomb group proteins are transcriptional repressors that play a central role in the establishment and maintenance of gene expression patterns during development. Using mice with an N-ethyl-N-nitrosourea (ENU)-induced mutation in Suppressor of Zeste 12 (Suz12), a core component of Polycomb Repressive Complex 2 (PRC2), we show here that loss of Suz12 function enhances hematopoietic stem cell (HSC) activity. In addition to these effects on a wild-type genetic background, mutations in Suz12 are sufficient to ameliorate the stem cell defect and thrombocytopenia present in mice that lack the thrombopoietin receptor (c-Mpl). To investigate the molecular targets of the PRC2 complex in the HSC compartment, we examined changes in global patterns of gene expression in cells deficient in Suz12. We identified a distinct set of genes that are regulated by Suz12 in hematopoietic cells, including eight genes that appear to be highly responsive to PRC2 function within this compartment. These data suggest that PRC2 is required to maintain a specific gene expression pattern in hematopoiesis that is indispensable to normal stem cell function
Glycerol Monolaurate and Dodecylglycerol Effects on Staphylococcus aureus and Toxic Shock Syndrome Toxin-1 In Vitro and In Vivo
BACKGROUND:Glycerol monolaurate (GML), a 12 carbon fatty acid monoester, inhibits Staphylococcus aureus growth and exotoxin production, but is degraded by S. aureus lipase. Therefore, dodecylglycerol (DDG), a 12 carbon fatty acid monoether, was compared in vitro and in vivo to GML for its effects on S. aureus growth, exotoxin production, and stability. METHODOLOGY/PRINCIPAL FINDINGS:Antimicrobial effects of GML and DDG (0 to 500 microg/ml) on 54 clinical isolates of S. aureus, including pulsed-field gel electrophoresis (PFGE) types USA200, USA300, and USA400, were determined in vitro. A rabbit Wiffle ball infection model assessed GML and DDG (1 mg/ml instilled into the Wiffle ball every other day) effects on S. aureus (MN8) growth (inoculum 3x10(8) CFU/ml), toxic shock syndrome toxin-1 (TSST-1) production, tumor necrosis factor-alpha (TNF-alpha) concentrations and mortality over 7 days. DDG (50 and 100 microg/ml) inhibited S. aureus growth in vitro more effectively than GML (p<0.01) and was stable to lipase degradation. Unlike GML, DDG inhibition of TSST-1 was dependent on S. aureus growth. GML-treated (4 of 5; 80%) and DDG-treated rabbits (2 of 5; 40%) survived after 7 days. Control rabbits (5 of 5; 100%) succumbed by day 4. GML suppressed TNF-alpha at the infection site on day 7; however, DDG did not (<10 ng/ml versus 80 ng/ml, respectively). CONCLUSIONS/SIGNIFICANCE:These data suggest that DDG was stable to S. aureus lipase and inhibited S. aureus growth at lower concentrations than GML in vitro. However, in vivo GML was more effective than DDG by reducing mortality, and suppressing TNF-alpha, S. aureus growth and exotoxin production, which may reduce toxic shock syndrome. GML is proposed as a more effective anti-staphylococcal topical anti-infective candidate than DDG, despite its potential degradation by S. aureus lipase
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