2,710 research outputs found

    Protocolo de actuación de Enfermería ante el Maltrato Infantil. Revisión Bibliográfica

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    [Resumen] El maltrato infantil es un problema que está teniendo un incremento preocupante en los últimos años. La mayor parte de estos casos se dan en personas de clase social baja, desempleo, alcoholismo… Y con el aumento de estas situaciones en nuestro país se ha producido un mayor número de casos. Aunque también cabe destacar que el maltrato infantil se encuentra en toda clase social. Ante este aumento se ha producido una necesidad de mejorar los mecanismos de coordinación interinstitucional en la prevención y la atención, lo cual ayude a una mejor formación y coordinación de los profesionales para lograr una detección precoz, una mejoría de la situación del niño y un descenso en el número de casos. El personal de enfermería tiene un papel fundamental en la prevención y detección precoz de los casos, pero diversos estudios demuestran el desconocimiento del personal enfermero respecto a su función en este tema, por eso nos planteamos la siguiente pregunta en este trabajo. ¿Cuál es la función de enfermería ante el maltrato infantil? Es por ello que se lleva a cabo una revisión bibliográfica consultando las principales bases de datos, en el ámbito de la salud. A lo largo de la revisión han sido seleccionados, un total de 9 artículos por ser aquellos que se adapten a los criterios de inclusión que se exponen en el trabajo. Esta revisión nos ha dejado claro que el trabajo de la enfermería es una parte muy importante para la reducción de casos de maltrato infantil, siempre trabajando coordinados con distintos profesionales dentro del personal sanitario como son: pediatras, psiquiatras, radiólogos o trabajadores sociales. A su vez este personal sanitario debe coordinarse con otros 4 estamentos claves para la reducción de casos de maltrato infantil como son el Educativo, Policial, Social y Judicial. Los enfermeros por su parte colaboran en este proceso recaudando la máxima información a través de distintas técnicas para la detección 6 | Protocolo enfermero ante el Maltrato Infantil. Revisión Bibliográfica. precoz de casos, y para el bienestar y la recuperación de aquellos que lo han padecido.Traballo fin de grao (UDC.FEP). Enfermaría. Curso 2014/201

    Approaching the violent stranger literary technics in the new journalism of the Salvadoran newspaper El Faro

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    Religion and Innovation in Europe: Implications for Product Life-Cycle Management

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    This paper analyzes the relationship between religion and innovation in Europe. To the best knowledge of the authors, no paper has been published about the association of religion with innovation and innovative products and services, at an individual level, for all the countries that belong to the European Union. This is the main goal of our paper. The results show that the orientation of innovativeness depends on religion. This study contains a segmentation of the main religions in Europe, taking into account their innovative profile. Connecting the characteristics of the religious segments found and the innovations life-cycle concept, companies have a tool to manage different innovations’ evolutive stages taking into consideration the religion of their customers. The European policy-makers, still dominated by a traditional innovation approach, gain a demand-side perspective to improve citizen’s innovativeness awareness and acceptance. Finally, religiosity does not seem to have a very strong relationship with attitudes towards innovation once we control for religious affiliation

    Le Sud dans le Nord. La rivière sans repos de Gabrielle Roy

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    L’estompage du primitivisme nordique sous la pression d’un Sud menaçant traduit la fragilité du territoire dans La rivière sans repos (1970), œuvre de Gabrielle Roy. Plus que le Nord, c’est le Sud dans le Nord qui semble s’inscrire dans ces récits. Par ailleurs, le va-et-vient des personnages, leurs voyages réels ou imaginaires entre la civilisation méridionale et les latitudes arctiques font émerger leur vulnérabilité, surtout dans le cas d’Elsa qui, anéantie par l’ébranlement identitaire, sombre dans l’aliénation

    TEDxBerkleeValencia

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    Description: This student organized a TEDx event at the Berklee Valencia campus featuring 12 speakers from all over the world. The topics of the talks ranged from dance to creating your own sound to food synced with music. This student was the marketing manager.https://remix.berklee.edu/graduate-studies-global-entertainment-business/1002/thumbnail.jp

    Why have poverty and income inequality increased so much? Argentina 1991-2002

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    This paper analyzes the sources of changes in poverty and income inequality among Argentine households during the 1991-2001 period. We assess the effect of changes in labor market participation, unemployment, education levels, and returns to human capital on income inequality and poverty by using a micro-simulation approach. This procedure allows us to evaluate the impact of each one of those changes on several measures of income inequality and poverty during the nineties. We found that unemployment accounts for a large part of the increase in income inequality and poverty that this country experienced in the last decade. In January 2002, Argentina declared the default on its external debt and devaluated the peso 40% ending the convertibility period. Since then, a growing inflation is affecting the purchasing power of Argentine households for the first time in more than ten years. Using our methodology we estimate the effect of the emerging inflation on poverty among households. Our findings indicate that inflation increases poverty significantly at least in the short run.Para cualquier uso del contenido del presente documento debe ponerse en contacto con el autor

    Usefulness of melatonin as complementary to chemotherapeutic agents at different stages of the angiogenic process

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    Chemotherapeutics are sometimes administered with drugs, like antiangiogenic compounds, to increase their effectiveness. Melatonin exerts antitumoral actions through antiangiogenic actions. We studied if melatonin regulates the response of HUVECs to chemotherapeutics (docetaxel and vinorelbine). The inhibition that these agents exert on some of the processes involved in angiogenesis, such as, cell proliferation, migratory capacity or vessel formation, was enhanced by melatonin. Regarding to estrogen biosynthesis, melatonin impeded the negative effect of vinorelbine, by decreasing the activity and expression of aromatase and sulfatase. Docetaxel and vinorelbine increased the expression of VEGF-A, VEGF-B, VEGF-C, VEGFR-1, VEGFR-3, ANG1 and/or ANG-2 and melatonin inhibited these actions. Besides, melatonin prevented the positive actions that docetaxel exerts on the expression of other factors related to angiogenesis like JAG1, ANPEP, IGF-1, CXCL6, AKT1, ERK1, ERK2, MMP14 and NOS3 and neutralized the stimulating actions of vinorelbine on the expression of FIGF, FGFR3, CXCL6, CCL2, ERK1, ERK2, AKT1, NOS3 and MMP14. In CAM assay melatonin inhibited new vascularization in combination with chemotherapeutics. Melatonin further enhanced the chemotherapeutics-induced inhibition of p-AKT and p-ERK and neutralized the chemotherapeuticscaused stimulatory effect on HUVECs permeability by modifying the distribution of VE cadherin. Our results confirm that melatonin blocks proangiogenic and potentiates antiangiogenic effects induced by docetaxel and vinorelbine enhancing their antitumor effectiveness.This work was supported by grants from the Spanish Economy and Competitiveness Ministry (SAF2016-77103-P) and from Instituto de Investigación Sanitaria Valdecilla (IDIVAL) (APG/12)

    Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF 7 human breast cancer cells

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    Results from clinical trials and multiple in vivo and in vitro studies point to melatonin as a promising adjuvant molecule with many beneficial effects when concomitantly administered with chemotherapy. Melatonin palliates side?effects and enhances the efficacy of chemotherapeutic agents. However, the mechanisms through which melatonin regulates molecular changes induced by chemotherapeutic agents remain largely unknown. In this study, we demonstrated that melatonin enhanced the anti-proliferative and apoptotic responses to low doses of docetaxel in breast cancer cells. Importantly, these effects were more potent when melatonin was added prior to docetaxel. Treatment with 1 µM docetaxel (equivalent to the therapeutic dosage) induced changes in gene expression profiles and melatonin modulated these changes. Specifically, docetaxel downregulated TP53, cyclin-dependent kinase inhibitor 1A (CDKN1A) and cadherin 13 (CDH13), and upregulated mucin 1 (MUC1), GATA binding protein 3 (GATA3) and c-MYC, whereas melatonin counteracted these effects. Melatonin further stimulated the expression of the pro-apoptotic BAD and BAX genes, and enhanced the inhibition of the anti-apoptotic gene BCL-2 induced by docetaxel. The findings of this study suggest that melatonin is a molecule with potential for use as an adjuvant in cancer chemotherapy, which may have implications for designing clinical trials using chemotherapeutic drugs in combination with melatonin.Acknowledgements: The present study was supported by grants from the Spanish Science Technology and Innovation Ministry (grant no. SAF2016 77103-P) and the Research Institute Valdecilla (grant no. APG/12)
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