Using LDGM Codes and Sparse Syndromes to Achieve Digital Signatures

In this paper, we address the problem of achieving efficient code-based digital signatures with small public keys. The solution we propose exploits sparse syndromes and randomly designed low-density generator matrix codes. Based on our evaluations, the proposed scheme is able to outperform existing solutions, permitting to achieve considerable security levels with very small public keys.Comment: 16 pages. The final publication is available at springerlink.co

Adverse events associated with nifurtimox treatment for chagas disease in children and adults

Nifurtimox (NF) is one of the only two drugs currently available for Chagas disease (ChD) treatment. However, data on NF safety are scarce, and many physicians defer or refuse NF treatment because of concerns about drug tolerance. In a retrospective study of adverse drug reactions (ADRs) associated with NF treatment of ChD, children received NF doses of 10 to 15 mg/kg/day for 60 to 90 days, and adults received 8 to 10 mg/kg/day for 30 days. A total of 215 children (median age, 2.6 years; range, 0 to 17 years) and 105 adults (median age, 34 years; range, 18 to 57 years) were enrolled. Overall, 127/320 (39.7%) patients developed ADRs, with an incidence of 64/105 adults and 63/215 children (odds ratio [OR] = 3.7; 95% confidence interval [CI], 2.2 to 6.3). We observed 215 ADRs, 131 in adults (median, 2 events/patient; interquartile range for the 25th to 75th percentiles [IQR25-75], 1 to 3) and 84 in children (median, 1 event/patient; IQR25-75 = 1 to 1.5) (Padjusted, 0.001). ADRs were mainly mild and moderate. Severe ADRs were infrequent (1.2% in children and 0.9% in adults). Nutritional, central nervous, and digestive systems were the most frequently affected, without differences between groups. Treatment was discontinued in 31/320 (9.7%) patients without differences between groups. However, ADR-related discontinuations occurred more frequently in adults than in children (OR = 5.5, 95% CI = 1.5 to 24). Our study supports the safety of NF for ChD treatment. Delaying NF treatment due to safety concerns does not seem to be supported by the evidence. (This study has been registered in ClinicalTrials.gov under identifier NCT04274101)

Dynamical properties of liquid Al near melting. An orbital-free molecular dynamics study

The static and dynamic structure of liquid Al is studied using the orbital free ab-initio molecular dynamics method. Two thermodynamic states along the coexistence line are considered, namely T = 943 K and 1323 K for which X-ray and neutron scattering data are available. A new kinetic energy functional, which fulfills a number of physically relevant conditions is employed, along with a local first principles pseudopotential. In addition to a comparison with experiment, we also compare our ab-initio results with those obtained from conventional molecular dynamics simulations using effective interionic pair potentials derived from second order pseudopotential perturbation theory.Comment: 15 pages, 12 figures, 2 tables, submitted to PR

The CaT strength in Seyfert nuclei revisited: analyzing young stars and non-stellar light contributions to the spectra

In a former paper (Garcia-Rissmann et al. 2005; hereafter Paper I), we have presented spectra of 64 active, 9 normal and 5 Starburst galaxies in the region around the near-IR Calcium triplet absorption lines and the [SIII]9069 line. In the present paper we analyze the CaT strength (WCaT), and kinematical products derived in that study, namely stellar and ionized gas velocity dispersions. Our main results may be summarized as follows: (1) Seyfert 2s show no sign of dilution in WCaT with respect to the values spanned by normal galaxies, even when optical absorption lines such as the CaII K band at 3933 A are much weaker than in old, bulge-like stellar populations. (2) The location of Seyfert 2s in the WCaT-WCaK plane is consistent with evolutionary synthesis models. The implication is that the source responsible for the dilution of optical lines in these AGN is a young stellar population, rather than an AGN featureless continuum, confirming the conclusion of the pioneer study of Terlevich, Diaz & Terlevich. (3) In Seyfert 1s, both W[SIII] and WCaT tend to be diluted due to the presence of a non-stellar component, in agreement with the unification paradigm. (4) A comparison of stellar and gas velocity dispersions confirms the existence of a correlation between the typical velocities of stars and clouds of the Narrow Line Region. The strength and scatter around this correlation are similar to those previously obtained from the [OIII]5007 line width.Comment: 14 pages, 15 figures. Paper accepted for publication in MNRA

Protection mechanisms for blast furnace crucible using titanium oxides

In modern steelmaking the duration of a working campaign for a blast furnace is related to the life of the crucible. Adding titanium oxide has been a frequent practice in the operation routines for modern blast furnaces, seeking the protection of the crucible walls, independently from its physical or chemical characteristics. These practices, as conventional operation of iron and steelmaking installations, present both advantages as well as undesirable consequences. The work proposes the incorporation of rutile (TiO2) or illmenite (FeO ·TiO2) in the refractory matrix of the linings, as a practice that results in a protection of the crucible without altering, under any circumstance, the regular operation of the installation

The Dense Molecular Gas and Nuclear Activity in the ULIRG IRAS 13120-5453

We present new ALMA Band 7 ($\sim340$ GHz) observations of the dense gas tracers HCN, HCO$^+$, and CS in the local, single-nucleus, ultraluminous infrared galaxy IRAS 13120-5453. We find centrally enhanced HCN (4-3) emission, relative to HCO$^+$ (4-3), but do not find evidence for radiative pumping of HCN. Considering the size of the starburst (0.5 kpc) and the estimated supernovae rate of $\sim1.2$ yr$^{-1}$, the high HCN/HCO$^+$ ratio can be explained by an enhanced HCN abundance as a result of mechanical heating by the supernovae, though the active galactic nucleus and winds may also contribute additional mechanical heating. The starburst size implies a high $\Sigma_{IR}$ of $4.7\times10^{12}$ $L_{\odot}$ kpc$^{-2}$, slightly below predictions of radiation-pressure limited starbursts. The HCN line profile has low-level wings, which we tentatively interpret as evidence for outflowing dense molecular gas. However, the dense molecular outflow seen in the HCN line wings is unlikely to escape the galaxy and is destined to return to the nucleus and fuel future star formation. We also present modeling of Herschel observations of the H$_2$O lines and find a nuclear dust temperature of $\sim40$ K. IRAS 13120-5453 has a lower dust temperature and $\Sigma_{IR}$ than is inferred for the systems termed "compact obscured nuclei" (such as Arp 220 and Mrk 231). If IRAS 13120-5453 has undergone a compact obscured nucleus phase, we are likely witnessing it at a time when the feedback has already inflated the nuclear ISM and diluted star formation in the starburst/AGN core.Comment: accepted for publication in ApJ, 21 pages, 11 figure

The nature of V39: an LBV candidate or LBV impostor in the very low metallicity galaxy IC 1613?

[abridged] Context: Very few examples of luminous blue variable (LBV) stars or LBV candidates (LBVc) are known, particularly at metallicities below the SMC. The LBV phase is crucial for the evolution of massive stars, and its behavior with metallicity is poorly known. V39 in IC 1613 is a well-known photometric variable, with B-band changes larger than 1mag. over its period. The star, previously proposed to be a projection of a Galactic W Virginis and an IC 1613 red supergiant, shows features that render it a possible LBVc. Method: We investigate mid-resolution blue and red VLT-VIMOS spectra of V39, covering a time span of 40 days, and perform a quantitative analysis of the combined spectrum using the model atmosphere code CMFGEN. Results: We identify strong Balmer and FeII P-Cygni profiles, and a hybrid spectrum resembling a B-A supergiant in the blue and a G-star in the red. No significant Vrad variations are detected, and the spectral changes are small over the photometric period. Our analysis places V39 in the low-luminosity part of the LBV and LBVc region, but it is also consistent with a sgB[e] star. Conclusions: The radial velocity indicates that V39 belongs to IC 1613. The lack of Vrad changes and spectroscopic variations excludes binary scenarios. The features observed are not consistent with a W Virginis star, and this possibility is also discarded. We propose that the star is a B-A LBVc or sgB[e] star surrounded by a thick disk precessing around it. If confirmed, V39 would be the lowest metallicity resolved LBV candidate known to date. Alternatively, it could represent a new transient phase of massive star evolution, an LBV impostor.Comment: In press at A&A. 10 pages, 11 figure

A higher proportion of eicosapentaenoic acid (EPA) when combined with docosahexaenoic acid (DHA) in omega-3 dietary supplements provides higher antioxidant effects in human retinal cells

Retinal pigment epithelium (RPE) is a key regulator of retinal function and is directly related to the transport, delivery, and metabolism of long-chain n-3 polyunsaturated fatty acids (n3-PUFA), in the retina. Due to their functions and location, RPE cells are constantly exposed to oxidative stress. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have shown to have antioxidant effects by different mechanisms. For this reason, we designed an in vitro study to compare 10 formulations of DHA and EPA supplements from different origins and combined in different proportions, evaluating their effect on cell viability, cell proliferation, reactive oxygen species production, and cell migration using ARPE-19 cells. Furthermore, we assessed their ability to rescue RPE cells from the oxidative conditions seen in diabetic retinopathy. Our results showed that the different formulations of n3-PUFAs have a beneficial effect on cell viability and proliferation and are able to restore oxidative induced RPE damage. We observed that the n3-PUFA provided different results alone or combined in the same supplement. When combined, the best results were obtained in formulations that included a higher proportion of EPA than DHA. Moreover, n3-PUFA in the form of ethyl-esters had a worse performance when compared with triglycerides or phospholipid based formulations