729 research outputs found

    Hannah Arendt, Thought and Evil.

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     En este artículo se da cuenta del análisis de dos conceptos centrales de la obra de Hannah Arendt: el mal radical y la banalidad del mal. En el desarrollo, se exploran las relaciones entre las condiciones del ser moral y el ser político. La tesis principal sostiene que la aparición del mal radical en la historia del siglo xx excluye la acción política de las relaciones humanas y que lo político nace en la pluralidad de las relaciones humanas, y su destrucción tiene que ver con la actitud irreflexiva, la incapacidad para pensar y juzgar las acciones propias y de las otras personas; sin embargo, el ámbito político puede ser protegido si las personas reafirman su diferencia, si son capaces de encontrarse consigo mismas en la actividad del pensamiento, al menos en ciertos momentos de crisis social. Puede que el pensamiento no proteja a los hombres de la maldad, pero sí mantiene la condición de la pluralidad humana.In this article, the analysis of two central concepts of the work of Hannah Arendt: the radical evil and the bana-lity of evil is realized. In development, the relationships between the conditions of the moral being and the poli-tical being are explored. The main thesis holds that the emergence of radical evil in the history of the twentieth century excludes the political action of human relations and that the political is born in the plurality of human relations, and its destruction has to do with unreflective attitude, To think and judge one’s own actions and those of other people; However, the political sphere can be protected if people reaffirm their difference if they are able to find themselves in the activity of thought, at least in certain moments of social crisis. Thought may not pro-tect men from evil, but it does maintain the condition of human plurality

    Hannah Arendt, el pensamiento y el mal

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      En este artículo se da cuenta del análisis de dos conceptos centrales de la obra de Hannah Arendt: el mal radical y la banalidad del mal. En el desarrollo, se exploran las relaciones entre las condiciones del ser moral y el ser político. La tesis principal sostiene que la aparición del mal radical en la historia del siglo xx excluye la acción política de las relaciones humanas y que lo político nace en la pluralidad de las relaciones humanas, y su destrucción tiene que ver con la actitud irreflexiva, la incapacidad para pensar y juzgar las acciones propias y de las otras personas; sin embargo, el ámbito político puede ser protegido si las personas reafirman su diferencia, si son capaces de encontrarse consigo mismas en la actividad del pensamiento, al menos en ciertos momentos de crisis social. Puede que el pensamiento no proteja a los hombres de la maldad, pero sí mantiene la condición de la pluralidad humana

    Hannah Arendt, el pensamiento y el mal

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    Este trabajo analiza dos conceptos centrales en la obra de Hannah Arendt: el mal radical y la banalidad del mal. En el desarrollo se explora las relaciones entre las condiciones del ser moral y el ser político. La tesis principal sostiene que la aparición del mal radical en la historia del siglo XX excluye la acción política de las relaciones humanas. Lo político nace en la pluralidad de las relaciones humanas, y su destrucción tiene que ver con la actitud irreflexiva, la incapacidad para pensar y juzgar las acciones propias y de las otras personas. Sin embargo, el ámbito político puede ser protegido si las personas reafirman su diferencia, si son capaces de encontrarse consigo mismos en la actividad del pensamiento, al menos en ciertos momentos de crisis social. Puede que el pensamiento no proteja a los hombres de la maldad, pero sí mantiene la condición de la pluralidad humana. / Abstract. This paper analyzes two central concepts in of Hannah Arendt‟s work: radical evil and the banality of evil. It explores the relationship between the conditions of the moral and political subject. The main thesis argues that the emergence of radical evil in the history of twentieth century excludes political action from human relationships. Political action is born in the plurality of human relationships and its destruction has to do with thoughtless attitude, inability to think and judge your own actions and those of others. However, the political sphere can be protected if people reaffirm their difference, if they can find themselves in the activity of thought, at least at certain moments of social crisis. Thinking may not protect men from evil, but maintains the condition of human plurality.Maestrí

    Snowfall events in the Cantabrian Mountains of northwestern Spain: WRF multiphysics ensemble assessment based on ground and multi-satellite observations

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    [EN] Snowfall in elevated areas of the mid-latitudes has a strong impact on infrastructure, freshwater availability, and the climate system. The Cantabrian Mountains of the northwestern Iberian Peninsula are very vulnerable to climate change because of their moderate altitudes, which limits their snowfall. Monitoring snow events is essential for the evaluation of weather and climate prediction models. However, measurement networks are scarce in mountainous areas and have great uncertainties because of blizzards. In this study, a multiphysics ensemble of the Weather Research and Forecasting (WRF) model was designed using three microphysics and two planetary boundary layer (PBL) schemes to simulate nine snowfall events in the Cantabrian Mountains during autumn and winter 2021–2022. The WRF was validated using several snow characteristics, such as liquid water equivalent, snow cover, and snow depth. Liquid water equivalent was evaluated using snow-gauge networks and satellite products in an assessment of snow cover. In addition, a monitoring network of webcams and snow poles was implemented, improving the low density of snow observations in the mountains. The results showed good model performance for detection of snow cover and slight overestimation of liquid water equivalent and snow thickness, which may have been caused by under-catchment that is generally an effect of wind on the measurement systems and by snow compaction, respectively. Morrison microphysics and Mellor-Yamada-Nakanishi-Niino (MYNN PBL) yielded better results for liquid water equivalent at higher altitudes and output greater snow cover. The results help determine the best configurations for snow modelling in the study area to develop future studies of the spatiotemporal patterns of snow distribution.S

    Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma

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    Fusions transcripts have been proven to be strong drivers for neoplasia-associated mutations, although their incidence in T-cell lymphoblastic lymphoma needs to be determined yet. Using RNA-Seq we have selected 55 fusion transcripts identified by at least two of three detection methods in the same tumour. We confirmed the existence of 24 predicted novel fusions that had not been described in cancer or normal tissues yet, indicating the accuracy of the prediction. Of note, one of them involves the proto oncogene TAL1. Other confirmed fusions could explain the overexpression of driver genes such as COMMD3-BMI1, LMO1 or JAK3. Five fusions found exclusively in tumour samples could be considered pathogenic (NFYG-TAL1, RIC3-TCRBC2, SLC35A3-HIAT1, PICALM MLLT10 and MLLT10-PICALM). However, other fusions detected simultaneously in normal and tumour samples (JAK3-INSL3, KANSL1-ARL17A/B and TFG-ADGRG7) could be germ-line fusions genes involved in tumour-maintaining tasks. Notably, some fusions were confirmed in more tumour samples than predicted, indicating that the detection methods underestimated the real number of existing fusions. Our results highlight the potential of RNA-Seq to identify new cryptic fusions, which could be drivers or tumour-maintaining passenger genes. Such novel findings shed light on the searching for new T-LBL biomarkers in these haematological disorders.The authors would like to thank the Spanish Biobanks integrated in the Spanish Hospital Biobanks Network (RetBioH; www.redbiobancos.es) for providing us with the necessary T-LBL samples to elaborate this work. We thank all patients who were willing to donate their samples without their support the research work would not be possible. And to Isabel Sastre for her technical support. This work was supported by the Spanish Ministry of Economy and Competitiveness (SAF2015-70561-R; MINECO/FEDER, EU); the Autonomous Community of Madrid, Spain (B2017/BMD-3778; LINFOMAS-CM) and the Spanish Association Against Cancer (AECC, 2018; PROYE18054PIRI). Institutional grants from the Fundación Ramón Areces and Banco de Santander are also acknowledged.S

    Mountain waves analysis in the vicinity of the Madrid-Barajas Airport using the WRF model

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    Turbulence and aircraft icing associated with mountain waves are weather phenomena potentially affecting aviation safety. In this paper, these weather phenomena are analysed in the vicinity of the Adolfo Su´arez Madrid-Barajas Airport (Spain). Mountain waves are formed in this area due to the proximity of the Guadarrama mountain range. Twenty different weather research and forecasting (WRF) model configurations are evaluated in an initial analysis. .is shows the incompetence of some experiments to capture the phenomenon. .e two experiments showing the best results are used to simulate thirteen episodes with observed mountain waves. Simulated pseudosatellite images are validated using satellite observations, and an analysis is performed through several skill scores applied to brightness temperature. Few differences are found among the different skill scores. Nevertheless, the .ompson microphysics scheme combined with the Yonsei university PBL scheme shows the best results. .e simulations produced by this scheme are used to evaluate the characteristic variables of the mountain wave episodes at windward and leeward and over the mountain. .e results show that north-northwest wind directions, moderate wind velocities, and neutral or slightly stable conditions are the main features for the episodes evaluated. In addition, a case study is analysed to evidence the WRF ability to properly detect turbulence and icing associated with mountain waves, even when there is no visual evidence available..is work was partially supported by the following research projects: PID2019-105306RB-I00, PCIN-2014-013-C07-04, and PCIN2016-080 (UE ERA-NET Plus NEWA Project), CGL2016-78702-C2-1-R and CGL2016-78702-C2-2-R (SAFEFLIGHT Project), FEI-EU-17-16 and SPESMARTand SPESVALE (ECMWF Special Projects)

    Major bleeding predictors in patients with left atrial appendage closure: The iberian registry II

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    Introduction and objective: Major bleeding events in patients undergoing left atrial appendage closure (LAAC) range from 2.2 to 10.3 per 100 patient-years in di erent series. This study aimed to clarify the bleeding predictive factors that could influence these di erences. Methods: LAAC was performed in 598 patients from the Iberian Registry II (1093 patient-years; median, 75.4 years). We conducted a multivariate analysis to identify predictive risk factors for major bleeding events. The occurrence of thromboembolic and bleeding events was compared to rates expected from CHA2DS2-VASc (congestive heart failure, hypertension, age, diabetes, stroke history, vascular disease, sex) and HAS-BLED (hypertension, abnormal renal and liver function, stroke, bleeding, labile INR, elderly, drugs or alcohol) scores. Results: Cox regression analysis revealed that age 75 years (HR: 2.5; 95% CI: 1.3 to 4.8; p = 0.004) and a history of gastrointestinal bleeding (GIB) (HR: 2.1; 95% CI: 1.1 to 3.9; p = 0.020) were two factors independently associated with major bleeding during follow-up. Patients aged <75 or 75 years had median CHA2DS2-VASc scores of 4 (IQR: 2) and 5 (IQR: 2), respectively (p < 0.001) and HAS-BLED scores were 3 (IQR: 1) and 3 (IQR: 1) for each group (p = 0.007). Events presented as follow-up adjusted rates according to age groups were stroke (1.2% vs. 2.9%; HR: 2.4, p = 0.12) and major bleeding (3.7 vs. 9.0 per 100 patient-years; HR: 2.4, p = 0.002). Expected major bleedings according to HAS-BLED scores were 6.2% vs. 6.6%, respectively. In patients with GIB history, major bleeding events were 6.1% patient-years (HAS-BLED score was 3.8 1.1) compared to 2.7% patients-year in patients with no previous GIB history (HAS-BLED score was 3.4 1.2; p = 0.029). Conclusions: In this high-risk population, GIB history and age 75 years are the main predictors of major bleeding events after LAAC, especially during the first year. Age seems to have a greater influence on major bleeding events than on thromboembolic risk in these patient

    Red de excelencia Cervera Hysgrid+: Comunidades locales energéticamente positivas con sistemas híbridos de generación renovable y almacenamiento

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    [ES] Las comunidades energéticas locales son un modelo clave para lograr una transición energética sostenible y justa cuyo despliegue en las redes de distribución dará lugar a multitud de beneficios ambientales y sociales, dando mayor seguridad al suministro y mayor soberanía energética a los consumidores. En este contexto, la red de excelencia Cervera HySGrid+ se ha constituido con el fin último de investigar y desarrollar soluciones tecnológicas novedosas que faciliten la creación de comunidades energéticas locales con balance neto positivo de alta eficiencia y basadas en sistemas híbridos de generación renovable y almacenamiento, así como para contribuir a desarrollar un marco regulatorio y de estandarización que faciliten su despliegue real.Este artículo se enmarca dentro de HySGrid+, una red española de Centros de Excelencia que cuenta con el apoyo del Ministerio de Ciencia e Innovación a través del organismo CDTI, en el marco del programa Cervera "CER-20191019.González-Cobos, N.; Arcos Usero, L.; Diaz-Cabrera, JC.; Riquelme Santos, JM.; Chicote, MA.; Samaniego Muñoz, J.; Bujedo Nieto, LÁ.... (2020). Red de excelencia Cervera Hysgrid+: Comunidades locales energéticamente positivas con sistemas híbridos de generación renovable y almacenamiento. Grupo Tecma Red. 144-149. http://hdl.handle.net/10251/178570S14414

    Avances en Informática y Automática. Décimo Workshop

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    [ES]El Máster Oficial en Sistemas Inteligentes de la Universidad de Salamanca tiene como principal objetivo promover la iniciación de los estudiantes en el ámbito de la investigación. El congreso organizado por el Departamento de Informática y Automática que se celebra dentro del Máster en Sistemas Inteligentes de la Universidad de Salamanca proporciona la oportunidad ideal para que sus estudiantes presenten los principales resultados de sus Trabajos de Fin de Máster y obtengan una realimentación del interés de los mismos. La décima edición del workshop “Avances en Informática y Automática”, correspondiente al curso 2015 - 2016, ha sido un encuentro interdisciplinar donde se han presentado trabajos pertenecientes a un amplio abanico de líneas de investigación, desde los sistemas biométricos y la visualización de la información hasta la minería de datos pasando por otros campos relacionados. Todos los trabajos han sido supervisados por investigadores de reconocido prestigio pertenecientes a la Universidad de Salamanca, proporcionando el marco idóneo para sentar las bases de una futura tesis doctoral. Entre los principales objetivos del congreso se encuentran: Ofrecer a los estudiantes un marco donde exponer sus primeros trabajos de investigación. Proporcionar a los participantes un foro donde discutir ideas y encontrar nuevas sugerencias de compañeros, investigadores y otros asistentes a la reunión. Permitir a cada estudiante una realimentación de los participantes sobre su trabajo y una orientación sobre las futuras direcciones de investigación. Contribuir al desarrollo del espíritu de colaboración en la investigación
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