Henri Temianka Correspondence; (getting)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/2176/thumbnail.jp

Characterization of Cracks in Thick Plates by Lamb Wave Diffraction Studies

The object of the work is a combined theroretical and experimental study of diffraction of Lamb waves by two- and three-dimensional cracks in a plate. An important motivation for this project is the desire to develop a technique capable of detecting and characterizing cracks in weldments in plates. We want to analyze the dependence of the scattered signals on the dimension, angle of inclination and depth of burial of the crack. The basic measurement techniques requires the accurate determination of minute normal surface displacements at ultrasonic frequencies. Such measurements have recently been made possible by the development in our laboratory of a new surface displacement capacitive tranducer [1]. The measured displacements will be compared with the theoretical predictions.</p

The interface between orthodontics and aesthetic dentistry.

The object of the work is a combined theroretical and experimental study of diffraction of Lamb waves by two- and three-dimensional cracks in a plate. An important motivation for this project is the desire to develop a technique capable of detecting and characterizing cracks in weldments in plates. We want to analyze the dependence of the scattered signals on the dimension, angle of inclination and depth of burial of the crack. The basic measurement techniques requires the accurate determination of minute normal surface displacements at ultrasonic frequencies. Such measurements have recently been made possible by the development in our laboratory of a new surface displacement capacitive tranducer [1]. The measured displacements will be compared with the theoretical predictions

Weak Functional Coupling of the Melanocortin-1 Receptor Expressed in Human Adipocytes

The melanocortin (MC) receptor type-1 (MC1-R) is the only one of the five MC receptor subtypes expressed in human adipose tissue explants, human mesenchymal stem cells (MSCs), and MSC-derived adipocytes. Following our recent expression studies (Obesity 2007, 15, 40-49), we now investigated the functional role of MC1-R in these tissues and cells to deduce the coupling state of MC1-R to intracellular output signals in human fat cells and tissue. Expression of MC1-R by undifferentiated and differentiated MSCs was quantified by real-time TaqMan PCR. Intracellular output signals (cAMP, lipolysis, secretion of IL-6, IL-10, and TNF-alpha), as well as effects on the metabolic rate and proliferation of human MSCs were analyzed by standard assays, exposing undifferentiated and differentiated MSCs and, in part, human adipose tissue explants to the potent MC1-R agonist, [Nle(4), D-Phe(7)]-alpha-MSH (NDP-MSH). This agonist induced a weak cAMP signal in MSC-derived adipocytes. However, it did not affect lipolysis in these cells or in adipose tissue explants, nor did it modulate cytokine release and mRNA expression of IL-6, IL-8, and TNF-alpha upon LPS stimulation. In undifferentiated MSCs, NDP-MSH did not alter the metabolic rate, but it showed a significant antiproliferative effect. Therefore, it appears that MC1-R-effector coupling in (differentiated) human adipocytes is too weak to induce a regulatory effect on lipolysis or inflammation; by contrast, MC1-R stimulation in undifferentiated MSCs induces an inhibitory signal on cell proliferation