TÓXICO. UN PROYECTO DE AUTOEDICIÓN

[ES] Este proyecto consiste en la autoedición de una tirada de siete ejemplares de un libro ilustrado mediante la técnica de la serigrafía. Cada ejemplar contiene tres libros numerados del 1 al 3, marcando el orden de lectura, en una caja contenedor. A lo largo del trabajo hablaremos sobre la autoedición, y más concretamente sobre el fanzine y la evolución desde sus inicios underground y los límites actuales entre, fanzine y otras publicaciones como libros de artista o libro ilustrado. En el desarrollo del proyecto hablaremos de la técnica de la serigrafía y trataremos el tema de los elementos interactivos propios de los libros infantiles, y como se aplican a esta y a otras publicaciones adultas.García Ortiz, M. (2015). TÓXICO. UN PROYECTO DE AUTOEDICIÓN. http://hdl.handle.net/10251/58929.TFG

WOMANHAUS. Historia ilustrada de las artistas de la Bauhaus

[ES] Un proyecto editorial que recorre la historia de la escuela alemana Bauhaus de la mano de sus alumnas y profesoras. Su lucha y sus obras en una época de cambios históricos. El objetivo de este trabajo es, aunando investigación y diseño, contar la historia de estas mujeres que ha quedado oculta y que sin embargo fue fundamental en el desarrollo de la famosa escuela y cuyo legado sigue vigente en el diseño actual.[EN] An editorial project that reviews the history of the German school Bauhaus by the hand of its female students and teachers. Her struggle and her works in a time of historical changes. The objective of this work is, joining research and design, to tell the story of these women who has been hidden and however was fundamental in the development of the famous school and whose legacy remains in force in the current design.García Ortiz, M. (2021). WOMANHAUS. Historia ilustrada de las artistas de la Bauhaus. Universitat Politècnica de València. http://hdl.handle.net/10251/178295TFG

Chloroplasts modulate elongation responses to canopy shade by retrograde pathways involving HY5 and abscisic acid

Plants use light as energy for photosynthesis but also as a signal of competing vegetation. Using different concentrations of norflurazon and lincomycin, we found that the response to canopy shade in Arabidopsis (Arabidopsis thaliana) was repressed even when inhibitors only caused a modest reduction in the level of photosynthetic pigments. High inhibitor concentrations resulted in albino seedlings that were unable to elongate when exposed to shade, in part due to attenuated light perception and signaling via phytochrome B and phytochrome-interacting factors. The response to shade was further repressed by a retrograde network with two separate nodes represented by the transcription factor LONG HYPOCOTYL 5 and the carotenoid-derived hormone abscisic acid. The unveiled connection among chloroplast status, light (shade) signaling, and developmental responses should contribute to achieve optimal photosynthetic performance under light-changing conditions

DOES LISTENING TO LIVE MUSIC DURING HEMODIALYSIS SESIONS AFFECT THE QUALITY OF LIFE?

Serrano, M.; Garcia-Testal, A.; Rico-Salvador, I.; Carrascosa López, C.; Ortiz Ramón, R.; Villalon Coca, J.; Royo-Maicas, P.... (2021). DOES LISTENING TO LIVE MUSIC DURING HEMODIALYSIS SESIONS AFFECT THE QUALITY OF LIFE?. Oxford University Press. 458-458. http://hdl.handle.net/10251/177492S45845

In vivo computer-aided diagnosis of colorectal polyps using white light endoscopy

Background and study aims Artificial intelligence is currently able to accurately predict the histology of colorectal polyps. However, systems developed to date use complex optical technologies and have not been tested in vivo. The objective of this study was to evaluate the efficacy of a new deep learning-based optical diagnosis system, ATENEA, in a real clinical setting using only high-definition white light endoscopy (WLE) and to compare its performance with endoscopists. Methods ATENEA was prospectively tested in real life on consecutive polyps detected in colorectal cancer screening colonoscopies at Hospital Clínic. No images were discarded, and only WLE was used. The in vivo ATENEA's prediction (adenoma vs non-adenoma) was compared with the prediction of four staff endoscopists without specific training in optical diagnosis for the study purposes. Endoscopists were blind to the ATENEA output. Histology was the gold standard. Results Ninety polyps (median size: 5 mm, range: 2-25) from 31 patients were included of which 69 (76.7 %) were adenomas. ATENEA correctly predicted the histology in 63 of 69 (91.3 %, 95 % CI: 82 %-97 %) adenomas and 12 of 21 (57.1 %, 95 % CI: 34 %-78 %) non-adenomas while endoscopists made correct predictions in 52 of 69 (75.4 %, 95 % CI: 60 %-85 %) and 20 of 21 (95.2 %, 95 % CI: 76 %-100 %), respectively. The global accuracy was 83.3 % (95 % CI: 74%-90 %) and 80 % (95 % CI: 70 %-88 %) for ATENEA and endoscopists, respectively. Conclusion ATENEA can accurately be used for in vivo characterization of colorectal polyps, enabling the endoscopist to make direct decisions. ATENEA showed a global accuracy similar to that of endoscopists despite an unsatisfactory performance for non-adenomatous lesions

The Neolithic of El Niño cave (Ayna, Albacete) in the Sierra del Segura context

Desde su excavación en el verano de 1973, la Cueva del Niño ha sido considerada un yacimiento de gran importancia para conocer el proceso de introducción de la economía de producción o de la tecnología cerámica en el sureste de la Península Ibérica, y especialmente para establecer cómo dicho proceso pudo haber afectado a las poblaciones ya asentadas en la región de la Sierra del Segura. Sin embargo, la información proporcionada por la Cueva del Niño resultaba muy fragmentaria, debido a la falta de un estudio de conjunto de las ocupaciones neolíticas del yacimiento. En este artículo, se presenta el análisis de las producciones cerámicas, la industria lítica y los restos de fauna, así como las dataciones existentes para los niveles holocenos del depósito. La revisión de las diversas evidencias proporcionadas por el yacimiento permite plantear que la Cueva del Niño habría actuado probablemente como una estación para el pastoreo y la caza, sirviendo como satélite de otros yacimientos de mayor entidad. No obstante, las limitaciones impuestas por el hecho de tratarse de una excavación efectuada hace cuarenta años impide aportar aspectos concluyentes sobre la dinámica del proceso de introducción del Neolítico en la Sierra del Segura.Since its excavation in the summer of 1973, El Niño cave has been considered a key site to understand the process of production economy and pottery technology introduction in South-eastern Iberian Peninsula, and especially to approach how such process could have affected people already settled in the Segura mountains. However, data from El Niño cave was very fragmentary, due to the lack of a broad study of Neolithic occupations of the site. In this paper, we present the analysis of pottery, lithic industry and faunal remains, as well as the existing dates from the site´s Holocene levels. The review of different evidence from the site allows suggesting that El Niño cave would have probably acted as a hunting and shepherding station, being a logistical site of larger places. However, limitations due to the fact that we are dealing with a 40- year-old excavation, prevent specifying how the process of Neolithic introduction in the Segura Mountains occurred

New Biocomposites for Innovative Construction Facades and Interior Partitions

Osirys is a European Research Project where a holistic solution for façades and interior partitions ready to be applied in building retrofitting and new construction has been developed. The project uses biocomposites as the base material to define different products: a multilayer façade, a curtain wall, a window, and an interior partition. The biocomposites developed have different functionalities able to meet the strictest requisites of the European Building Codes in relation to fire and structural performance, improve indoor air quality through the elimination of VOCs (volatile organic compounds) and microorganisms, increase thermal insulation, and increase the durability of construction elements. The new systems are lighter than traditional ones, leading to reductions in overall weight, thereby reducing implementation costs during both manufacturing and assembly processes, thanks to an industrialised concept that utilises modular elements. The project was developed with the collaboration of 18 European partners (5 research centres, 9 SMEs, 2 large industries, and 2 public bodies). The main activities were devoted to the establishment of requirements, the development of materials, the design of products, the integration of materials into products, the verification of properties by simulation and testing according to EU standards, the integration of products into real buildings, and economic and environmental assessment. The scope of this paper is to provide a general overview of the entire project work and results to demonstrate the feasibility of using biocomposites in envelope solutions with the aim of solving some of the main problems that exist in façade traditional solutions. The project finishes with the implementation of the developments in real buildings as prototypes; further research is required before industrial scale manufacturing of the systems can be launched into the market.This work was supported by the EU under the 7th Framework programme of research, technological development, and demonstration project titled: “Forest based composites for façades and interior partitions to improve indoor air quality in new builds and restoration” under grant agreement nº 609067. The development of this article and of this project would not have been possible without the collaboration of all consortium partners: Fundación Tecnalia, Acciona Infraestructuras, Teknologian Tutkimuskeskus VTT, Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung EV, Research Association of Plastic and Related Materials (AIMPLAS), IVL Svenska Miljoeinstitutet AB, Tartu Stad, Tecnaro Gesellschaft zur Industriellen Anwendung Nachwachsender Rohstoffe MBH, Netcomposites Limited, Omikron-Dokk Muanyagiparo kft, Conenor Oy, Van Berkel & Bos UN STUDIO B.V., Amorim Cork Composites SA, ENAR Envolventes arquitectónicas, Bergamo Tecnologie Spzoo, VISESA, SICC GMBH and Collanti Concorde SRL

Paromomycin is superior to metronidazole in Dientamoeba fragilis treatment

Dientamoeba fragilis is a trichomonad parasite of the human intestine that is found worldwide. However, the biological cycle and transmission of this parasite have yet to be elucidated. Although its pathogenic capacity has been questioned, there is increasing evidence that clinical manifestations vary greatly. Different therapeutic options with antiparasitic drugs are currently available; however, very few studies have compared the effectiveness of these drugs. In the present longitudinal study, we evaluate 13,983 copro-parasitological studies using light microscopy of stools, during 2013-2015, in Terrassa, Barcelona (Spain). A total of 1150 (8.2%) presented D. fragilis. Of these, 739 episodes were finally analyzed: those that involved a follow-up parasitology test up to 3 months later, corresponding to 586 patients with gastrointestinal symptoms (53% under 15 years of age). Coinfection by Blastocystis hominis was present in 33.6% of the subjects. Our aim was to compare therapeutic responses to different antiparasitic drugs and the factors associated with the persistence of D. fragilis post-treatment. Gender, age, and other intestinal parasitic coinfections were not associated with parasite persistence following treatment. Metronidazole was the therapeutic option in most cases, followed by paromomycin: 65.4% and 17.5% respectively. Paromomycin was found to be more effective at eradicating parasitic infection than metronidazole (81.8% vs. 65.4%; p = 0.007), except in children under six years of age (p = 0.538). Although Dientamoeba fragilis mainly produces mild clinical manifestations, the high burden of infection means we require better understanding of its epidemiological cycle and pathogenicity, as well as adequate therapeutic guidelines in order to adapt medical care and policies to respond to this health problem

El Niño Cave (Aýna, Albacete, Spain): Late Middle Palaeolithic, Rock Art, and Neolithic Occupations from Inland Iberia

RESUMEN: La Cueva del Niño, situada en el reborde sudeste de la Meseta castellana, alberga una secuencia discontinua que abarca desde el Paleolítico Medio hasta el Neolítico, además de pinturas rupestres paleolíticas y de estilo Levantino. Se trata por lo tanto de un yacimiento clave para comprender la ocupación del interior de la Península Ibérica durante el Paleolítico y la Prehistoria Reciente. Este artículo recoge los principales resultados de un proyecto multidisciplinar destinado a definir las diferentes ocupaciones del yacimiento a lo largo de la Prehistoria.ABSTRACT: El Niño cave, located on the south-eastern border of the Spanish Meseta, hosts a discontinuous sequence including Middle Palaeolithic and Neolithic levels, along with Upper Palaeolithic and Levantine style paintings. It is a key site for understanding human occupations of inland Iberia during the Palaeolithic and early prehistory. This paper summarises the main results of a multidisciplinary project aimed at defining the prehistoric human occupations at the site