Dedicatoria

Dedicatori

Guiding Jurors’ Damage Award Decisions: Experimental Investigations of Approaches Based on Theory and Practice

This is the author accepted manuscript. The final version is available from the American Psychological Association via the DOI in this recordTheory and practitioner “scaling” advice informed hypotheses that guidance to mock jurors should (a) increase validity (vertical equity), decrease variability (reliability), and improve coherence in awards; (b) improve subjective experience of jurors’ decision-making (rated helpfulness, confidence, and difficulty); and (c) have the greatest impact when it includes both verbal and numerical benchmarks. Three mock juror experiments (N = 197 students, N = 476 Amazon Mechanical Turk workers, and N = 391 students) tested novel scaling approaches and predictions from the Hans-Reyna model of damage award decision-making. Jurors reviewed a legal case and provided a dollar award to compensate plaintiffs for pain and suffering following concussions. Experiments varied injury severity (low vs. high) and the plaintiff attorney’s guidance (no guidance, verbal guidance, numerical guidance, and verbal-plus-numerical guidance) between subjects. Results support predictions that, even without guidance, mock jurors appropriately categorize the gist of injuries as low or high severity, and dollar awards reflect that gist. Participants gave a higher award for more severe injuries, indicating that they extracted the qualitative gist of damages. Also, as expected, guidance, particularly verbal-plus-numerical guidance, had beneficial effects on jurors’ subjective experience, with participants reporting that it was a helpful aid in decision-making. Numerical guidance, both with and without verbal guidance, reduced award variability in severe injury cases in all three experiments. Scaling guidance did not improve the already strong gist-verbatim correspondence or award validity. Both grasping the gist of damages and mapping that gist onto numbers are important, but jurors appear to benefit from assistance with numerical mapping

Self-Assembling Peptide Detergents Stabilize Isolated Photosystem Ion a Dry Surface for an Extended Time

We used a class of designed peptide detergents to stabilize photosystem I (PS-I) upon extended drying under N(2) on a gold-coated-Ni-NTA glass surface. PS-I is a chlorophyll-containing membrane protein complex that is the primary reducer of ferredoxin and the electron acceptor of plastocyanin. We isolated the complex from the thylakoids of spinach chloroplasts using a chemical detergent. The chlorophyll molecules associated with the PS-I complex provide an intrinsic steady-state emission spectrum between 650 and 800 nm at −196.15 °C that reflects the organization of the pigment-protein interactions. In the absence of detergents, a large blue shift of the fluorescence maxima from approximately 735 nm to approximately 685 nm indicates a disruption in light-harvesting subunit organization, thus revealing chlorophyll−protein interactions. The commonly used membrane protein-stabilizing detergents, N-dodecyl-β-D-maltoside and N-octyl-β-D-glucoside, only partially stabilized the approximately 735-nm complex with approximately 685-nm spectroscopic shift. However, prior to drying, addition of the peptide detergent acetyl- AAAAAAK at increasing concentration significantly stabilized the PS-I complex. Moreover, in the presence of acetyl- AAAAAAK, the PS-I complex is stable in a dried form at room temperature for at least 3 wk. Another peptide detergent, acetyl-VVVVVVD, also stabilized the complex but to a lesser extent. These observations suggest that the peptide detergents may effectively stabilize membrane proteins in the solid-state. These designed peptide detergents may facilitate the study of diverse types of membrane proteins

Dark matter distribution in Milky Way-analog galaxies

Our current understanding of how dark matter (DM) is distributed within the Milky Way (MW) halo, particularly in the solar neighborhood, is based on either careful studies of the local stellar orbits or model assumptions on the global shape of the MW halo. In this work, we undertake a study of external galaxies, with the intent of providing insight to the DM distribution in MW-analog galaxies. For this, we carefully select a sample of galaxies similar to the MW, based on maximum atomic hydrogen (HI) rotational velocity (v=200-280 km s^{-1}) and morphological type (Sab-Sbc) criteria. With a need for deep, highly-resolved HI, our resulting sample is composed of 5 galaxies from the VIVA and THINGS surveys. To perform our baryonic analysis, we use deep Spitzer mid-IR images at 3.6 and 4.5 {\mu}m from the S4G survey. Based on the dynamical three-dimensional modeling software 3D-Barolo, we construct RCs and derive the gas and stellar contributions from the galaxy\'s gaseous- and stellar-disks mass surface density profiles. Through a careful decomposition of their rotation curves into their baryonic (stars, gas) and DM components, we isolate the DM contribution by using an MCMC-based approach. Based on the Sun\'s location and the MW\'s R_{25}, we define the corresponding location of the solar neighborhood in these systems. We put forward a window for the DM density (\rho=0.21-0.46 GeV cm^{-3}) at these galactocentric distances in our MW analog sample, consistent with the values found for the MW\'s local DM density, based on more traditional approaches found in the literature.Comment: 16 pages, 6 figures, 3 tables, submitted to Ap

Quantifying the impact of the Large Magellanic Cloud on the structure of the Milky Way's dark matter halo using Basis Function Expansions

Indications of disequilibrium throughout the Milky Way (MW) highlight the need for compact,flexible, non-parametric descriptions of phase--space distributions of galaxies. We present a new representation of the current Dark Matter (DM) distribution and potential derived from N-body simulations of the Milky Way and Large Magellanic Cloud (LMC) system using Basis Function Expansions (BFEs). We incorporate methods to maximize the physical signal in the representation. As a result, the simulations of $10^8$ DM particles representing the MW--LMC system can be described by 354 coefficients. We find that the LMC induces asymmetric perturbations (odd l, m) to the MW's halo, which are not well-described by oblate, prolate, or triaxial halos. Furthermore, the energy in high-order even modes (l,m $\geq$ 2) is similar to average triaxial halos found in cosmological simulations. As such, the response of the MW's halo to the LMC must be accounted for in order to recover the imprints of its assembly history. The LMC causes the outer halo ($\geq$ 30 kpc) to shift from the disk center of mass (COM) by $\sim$15-25 kpc at present day, manifesting as a dipole in the BFE and in the radial velocities of halo stars. The shift depends on the LMC's infall mass, the distortion of the LMC's halo and the MW halo response. Within 30 kpc, halo tracers are expected to orbit the COM of the MW's disk, regardless of LMC infall mass. The LMC's halo is also distorted by MW tides, we discuss the implications for its mass loss and the subsequent effects on current Magellanic satellites.Comment: 35 pages, 25 figures, Accepted for publication in ApJ. 3d movie can be found here: https://vimeo.com/54620711

The Relative Impact of Climate Change on the Extinction Risk of Tree Species in the Montane Tropical Andes.

There are widespread concerns that anthropogenic climate change will become a major cause of global biodiversity loss. However, the potential impact of climate change on the extinction risk of species remains poorly understood, particularly in comparison to other current threats. The objective of this research was to examine the relative impact of climate change on extinction risk of upper montane tree species in the tropical Andes, an area of high biodiversity value that is particularly vulnerable to climate change impacts. The extinction risk of 129 tree species endemic to the region was evaluated according to the IUCN Red List criteria, both with and without the potential impacts of climate change. Evaluations were supported by development of species distribution models, using three methods (generalized additive models, recursive partitioning, and support vector machines), all of which produced similarly high AUC values when averaged across all species evaluated (0.82, 0.86, and 0.88, respectively). Inclusion of climate change increased the risk of extinction of 18-20% of the tree species evaluated, depending on the climate scenario. The relative impact of climate change was further illustrated by calculating the Red List Index, an indicator that shows changes in the overall extinction risk of sets of species over time. A 15% decline in the Red List Index was obtained when climate change was included in this evaluation. While these results suggest that climate change represents a significant threat to tree species in the tropical Andes, they contradict previous suggestions that climate change will become the most important cause of biodiversity loss in coming decades. Conservation strategies should therefore focus on addressing the multiple threatening processes currently affecting biodiversity, rather than focusing primarily on potential climate change impacts

Desenvolvimento de ontologias e linguagem de domínio específico para análises de complexidade semântica em nanotecnologia agrícola.

A Nanotecnologia consiste no conjunto de técnicas utilizadas para visualização, caracterização, produção e manipulação da matéria na escala de átomos e moléculas (escala nano). As vantagens e aplicações são inúmeras, por isso estratégias de mineração e análises textuais são relevantes para a elaboração de estruturas de genealogia acadêmica para elaboração de grafos que permitam identificar os limites da fronteira do conhecimento e estabelecer métricas para definição de estratégias e políticas de incentivo à pesquisa. Nesse contexto foram empregadas ferramentas de busca acadêmica orientadas a ampliar e analisar um número maior de artigos científicos para permitir a seleção e sistematização das informações técnicas mais relevantes para a Nanotecnologia na Agricultura, para as bases de ontologias agrícolas. Na área de Nanotecnologia foram realizadas buscas em bases científicas internacionais, além de relatório institucionais. Para o desenvolvimento das ontologias foi utilizada a ferramenta Protege utilizando o plugin de OWL e algumas ontologias foram representadas utilizando (CMap). A ontologia final dos descritores da Nanotecnologia para agricultura gerou um mapa conceitual com um framework de organização para os dados de riscos mais relevantes para a liberação e uso da tecnologia. ?- Nanotechnology consists of the set of techniques used for visualization, characterization, production and manipulation of matter at the scale of atoms and molecules (nano scale). The advantages and applications are numerous, so data mining strategies and textual analysis are relevant for the proposition of academic genealogy structures and for the formulation of graphs that allow to identify the limits of the knowledge frontier and to establish metrics for the definition of strategies and policies to encourage search. In this context, academic search tools were used to expand and analyze a larger number of scientific articles to allow the selection and systematization of the most relevant technical information for Nanotechnology in Agriculture, in agricultural ontologies issue. In the area of nanotechnologies it was carried out searches on international scientific bases, as well as institutional reports. For the development of the ontology the Protege tool was used using the OWL plugin and some indicators were showed using the CMap toll. The final ontology of the descriptors of nanotechnology for agriculture generated a conceptual map with an organization framework for the most relevant risk data for the release and use of technology

Patterns of Sequence Divergence and Evolution of the S1 Orthologous Regions between Asian and African Cultivated Rice Species

A strong postzygotic reproductive barrier separates the recently diverged Asian and African cultivated rice species, Oryza sativa and O. glaberrima. Recently a model of genetic incompatibilities between three adjacent loci: S1A, S1 and S1B (called together the S1 regions) interacting epistatically, was postulated to cause the allelic elimination of female gametes in interspecific hybrids. Two candidate factors for the S1 locus (including a putative F-box gene) were proposed, but candidates for S1A and S1B remained undetermined. Here, to better understand the basis of the evolution of regions involved in reproductive isolation, we studied the genic and structural changes accumulated in the S1 regions between orthologous sequences. First, we established an 813 kb genomic sequence in O. glaberrima, covering completely the S1A, S1 and the majority of the S1B regions, and compared it with the orthologous regions of O. sativa. An overall strong structural conservation was observed, with the exception of three isolated regions of disturbed collinearity: (1) a local invasion of transposable elements around a putative F-box gene within S1, (2) the multiple duplication and subsequent divergence of the same F-box gene within S1A, (3) an interspecific chromosomal inversion in S1B, which restricts recombination in our O. sativa×O. glaberrima crosses. Beside these few structural variations, a uniform conservative pattern of coding sequence divergence was found all along the S1 regions. Hence, the S1 regions have undergone no drastic variation in their recent divergence and evolution between O. sativa and O. glaberrima, suggesting that a small accumulation of genic changes, following a Bateson-Dobzhansky-Muller (BDM) model, might be involved in the establishment of the sterility barrier. In this context, genetic incompatibilities involving the duplicated F-box genes as putative candidates, and a possible strengthening step involving the chromosomal inversion might participate to the reproductive barrier between Asian and African rice species