A simple model for the evolution of the dust population in protoplanetary disks

Context: The global size and spatial distribution of dust is an important ingredient in the structure and evolution of protoplanetary disks and in the formation of larger bodies, such as planetesimals. Aims: We aim to derive simple equations that explain the global evolution of the dust surface density profile and the upper limit of the grain size distribution and which can readily be used for further modeling or for interpreting of observational data. Methods: We have developed a simple model that follows the upper end of the dust size distribution and the evolution of the dust surface density profile. This model is calibrated with state-of-the-art simulations of dust evolution, which treat dust growth, fragmentation, and transport in viscously evolving gas disks. Results: We find very good agreement between the full dust-evolution code and the toy model presented in this paper. We derive analytical profiles that describe the dust-to-gas ratios and the dust surface density profiles well in protoplanetary disks, as well as the radial flux by solid material "rain out", which is crucial for triggering any gravity assisted formation of planetesimals. We show that fragmentation is the dominating effect in the inner regions of the disk leading to a dust surface density exponent of -1.5, while the outer regions at later times can become drift-dominated, yielding a dust surface density exponent of -0.75. Our results show that radial drift is not efficient in fragmenting dust grains. This supports the theory that small dust grains are resupplied by fragmentation due to the turbulent state of the disk.Comment: 12 pages, 10 figures, accepted to A&

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies

Monoclonal anti-SARS-CoV-2 immunoglobulins represent a treatment option for COVID-19. However, their production in mammalian cells is not scalable to meet the global demand. Single-domain (VHH) antibodies (also called nanobodies) provide an alternative suitable for microbial production. Using alpaca immune libraries against the receptor-binding domain (RBD) of the SARS-CoV-2 Spike protein, we isolated 45 infection-blocking VHH antibodies. These include nanobodies that can withstand 95°C. The most effective VHH antibody neutralizes SARS-CoV-2 at 17–50 pM concentration (0.2–0.7 µg per liter), binds the open and closed states of the Spike, and shows a tight RBD interaction in the X-ray and cryo-EM structures. The best VHH trimers neutralize even at 40 ng per liter. We constructed nanobody tandems and identified nanobody monomers that tolerate the K417N/T, E484K, N501Y, and L452R immune-escape mutations found in the Alpha, Beta, Gamma, Epsilon, Iota, and Delta/Kappa lineages. We also demonstrate neutralization of the Beta strain at low-picomolar VHH concentrations. We further discovered VHH antibodies that enforce native folding of the RBD in the E. coli cytosol, where its folding normally fails. Such “fold-promoting” nanobodies may allow for simplified production of vaccines and their adaptation to viral escape-mutations

Cometary dust analogues for physics experiments

The CoPhyLab (Cometary Physics Laboratory) project is designed to study the physics of comets through a series of earth-based experiments. For these experiments, a dust analogue was created with physical properties comparable to those of the non-volatile dust found on comets. This "CoPhyLab dust" is planned to be mixed with water and CO$_2$ ice and placed under cometary conditions in vacuum chambers to study the physical processes taking place on the nuclei of comets. In order to develop this dust analogue, we mixed two components representative for the non-volatile materials present in cometary nuclei. We chose silica dust as representative for the mineral phase and charcoal for the organic phase, which also acts as a darkening agent. In this paper, we provide an overview of known cometary analogues before presenting measurements of eight physical properties of different mixtures of the two materials and a comparison of these measurements with known cometary values. The physical properties of interest are: particle size, density, gas permeability, spectrophotometry, mechanical, thermal and electrical properties. We found that the analogue dust that matches the highest number of physical properties of cometary materials consists of a mixture of either 60\%/40\% or 70\%/30\% of silica dust/charcoal by mass. These best-fit dust analogue will be used in future CoPhyLab experiments

First detection of a diamagnetic cavity at comet 67P/Churyumov-Gerasimenko

International audienceContext: The Rosetta magnetometer RPC-MAG has been exploring the plasma environment of comet 67P/Churyumov-Gerasimenko since August 2014. The first months were dominated by low-frequency waves which evolved into more complex features. However, at the end of July 2015, close to perihelion, the magnetometer detected a region that did not contain any magnetic field at all.Aims: These signatures match the appearance of a diamagnetic cavity as was observed at comet 1P/Halley in 1986. The cavity here is more extended than previously predicted by models and features unusual magnetic field configurations, which need to be explainedMethods: The onboard magnetometer data were analyzed in detail and used to estimate the outgassing rate. A minimum variance analysis was used to determine boundary normals.Results. Our analysis of the data acquired by the Rosetta Plasma Consortium instrumentation confirms the existence of a diamagnetic cavity. The size is larger than predicted by simulations, however. One possible explanation are instabilities that are propagating along the cavity boundary and possibly a low magnetic pressure in the solar wind. This conclusion is supported by a change in sign of the Sun-pointing component of the magnetic field. Evidence also indicates that the cavity boundary is moving with variable velocities ranging from 230−500 m/s

Phase-curve analysis of comet 67P/Churyumov-Gerasimenko at small phase angles

Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Open Access funding provided by Max Planck Society.The Rosetta-OSIRIS images acquired at small phase angles in three wavelengths during the fly-by of the spacecraft on 9-10 April 2016 provided a unique opportunity to study the opposition effect on the surface of comet 67P/Churyumov-Gerasimenko (67P). Our goal is to study phase curves of the nucleus at small phase angles for a variety of surface structures to show the differences in their opposition effect and to determine which surface properties cause the differences.© N. Masoumzadeh et al. 2019OSIRIS was built by a consortium of the Max-Planck-Institut fur Sonnensystemforschung, Gottingen, Germany; the CISAS University of Padova, Italy; the Laboratoire d'Astrophysique de Marseille, France; the Instituto de Astrofisica de Andalucia, CSIC, Granada, Spain; the Research and Scientific Support Department of the ESA, Noordwijk, Netherlands; the Instituto Nacional de Tecnica Aeroespacial, Madrid, Spain; the Universidad Politechnica de Madrid, Spain; the Department of Physics and Astronomy of Uppsala University, Sweden; and the Institut fur Datentechnik und Kommunikationsnetze der Technischen Universitat Braunschweig, Germany. The support of the national funding agencies of Germany (DLR), France (CNES), Italy (ASI), Spain (MEC), Sweden (SNSB), and the ESA Technical Directorate is gratefully acknowledged. We thank the Rosetta Science Operations Centre and the Rosetta Mission Operations Centre for the successful rendezvous with comet 67P/Churyumov-Gerasimenko. This research has made use of the USGS Integrated Software for Imagers and Spectrometers (ISIS). We gratefully acknowledge the developers of SPICE and NAIF/PDS resources. This research has made use of the scientific software shapeViewer www.comet-toolbox.com.L.K.acknowledges a support from the NASA SSW grant 80NSSC17K0731

Surface evolution of the Anhur region on comet 67P/Churyumov-Gerasimenko from high-resolution OSIRIS images

Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The southern hemisphere of comet 67P/Churyumov-Gerasimenko (67P) became observable by the Rosetta mission in March 2015, a few months before cometary southern vernal equinox. The Anhur region in the southern part of the comet's larger lobe was found to be highly eroded, enriched in volatiles, and highly active. Aims. We analyze high-resolution images of the Anhur region pre- and post-perihelion acquired by the OSIRIS imaging system on board the Rosetta mission. The Narrow Angle Camera is particularly useful for studying the evolution in Anhur in terms of morphological changes and color variations. Methods. Radiance factor images processed by the OSIRIS pipeline were coregistered, reprojected onto the 3D shape model of the comet, and corrected for the illumination conditions. Results. We find a number of morphological changes in the Anhur region that are related to formation of new scarps; removal of dust coatings; localized resurfacing in some areas, including boulders displacements; and vanishing structures, which implies localized mass loss that we estimate to be higher than 50 million kg. The strongest changes took place in and nearby the Anhur canyon-like structure, where significant dust cover was removed, an entire structure vanished, and many boulders were rearranged. All such changes are potentially associated with one of the most intense outbursts registered by Rosetta during its observations, which occurred one day before perihelion passage. Moreover, in the niche at the foot of a new observed scarp, we also see evidence of water ice exposure that persisted for at least six months. The abundance of water ice, evaluated from a linear mixing model, is relatively high (>20%). Our results confirm that the Anhur region is volatile-rich and probably is the area on 67P with the most pristine exposures near perihelion.© S. Fornasier et al. 2019OSIRIS was built by a consortium led by the Max-Planck-Institut fur Sonnensystemforschung, Goettingen, Germany, in collaboration with CISAS, University of Padova, Italy, the Laboratoire d'Astrophysique de Marseille, France, the Instituto de Astrofisica de Andalucia, CSIC, Granada, Spain, the Scientific Support Office of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Tecnica Aeroespacial, Madrid, Spain, the Universidad Politechnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut fur Datentechnik und Kommunikationsnetze der Technischen Universitat Braunschweig, Germany. The support of the national funding agencies of Germany (DLR), France (CNES), Italy (ASI), Spain (MEC), Sweden (SNSB), and the ESA Technical Directorate is gratefully acknowledged. We thank the Rosetta Science Ground Segment at ESAC, the Rosetta Mission Operations Centre at ESOC and the Rosetta Project at ESTEC for their outstanding work enabling the science return of the Rosetta Mission. SF acknowledges the financial support from the France Agence Nationale de la Recherche (programme Classy, ANR-17-CE31-0004). The authors thank Dr. E. Howell for her comments and suggestions which helped us to improve this article