Aroma Fingerprint Characterisation of La Mancha Red Wines

In the present study, Rojal, Moravia Dulce and Tortosí wines were elaborated across four harvests (2006to 2009) from minority red grape varieties cultivated in the La Mancha region of Spain. Wines werestudied by instrumental and sensory analysis to determine the influence of grape variety on the aromaof the wine. Aroma compounds were isolated by solid phase extraction (SPE) to later be analysed usinggas chromatography–mass spectrometry (GC/MS). The odour activity values (OAVs) for the differentcompounds were classified into seven odorant series that describe the aroma profile of these wines (1: fruity,2: floral, 3: green/fresh, 4: sweet, 5: spice, 6: fatty, and 7: other odours). The total intensities of everyaromatic series were calculated as sum of the OAV of each one of the compounds assigned to this series. Allwines showed the same sequence, with the highest aroma contribution being those of the sweet and fruityseries, followed by fatty. The sensory profile of Rojal, Moravia Dulce and Tortosí wines was evaluated byexperienced wine tasters using a non-structured scale. The panellists founded several differences betweentheir sensory profiles. This study provides a complete aromatic characterisation of these wines

Afectación tumoral del sistema nervioso periférico

Se han estudiado 18 pacientes con afectación del S.N.P. por lesiones tumorales tratados en nuestra unidad en un período de 8 años. La mayoría de estos tumores tenían una localización intraneural (14 casos), eran de naturaleza benigna (13 casos) y afectaban al miembro superior. La prueba diagnóstica más exacta fue la R.M.N. Destacamos la existencia en nuestra seria de algunos tumores de rara presentación en la clínica, como un caso de fibrolipoma, condroma intraneural y neurosarcoma de la variedad "Tritón", respectivamente.Eighteen patients who had tumours of peripheral nerves have been studied retrospectively. They were treated in our department for eight years. Most of these tumours were placed intraneuraly (14 cases), were benignant (13 cases), and located in the upper limb. The most precise test for diagnosis was the MRI. We want to emphasize the existence in our series of some tumours which rarely appears in clinic, for example a Fibrolipoma, a intraneural chondroma and a malignant triton tumour

Virtual reality in rehabilitation: WIITM as an occupational therapy tool in patients with spinal cord injuries

The use of virtual reality has gained importance in the rehabilitation sector over the last few years. The Wii™ console complements traditional treatment by exercising the motor skills in a motivating context, which is important in long-term interventions, such as spinal cord injury. Objectives: to describe our work with the Wii™ console and the different support products used in occupational therapy at the Fundación del Lesionado Medular, and to discuss advantages and disadvantages. Method: 63 patients with spinal cord injury (of whom 46 with quadriplegia and 17 with paraplegia), treated over the period of one year in weekly 30-minute sessions. Results: motor-skill improvements, more involvement of the patients in the treatment. Conclusion: the features of the console and the support products created by our department make the Wii™ accessible to patients, increase their motivation and enrich the treatment

Transcriptomic analysis of a near-isogenic line of melon with high fruit flesh firmness during ripening

This is the peer reviewed version of the following article: Zarid, M., García-Carpintero, V., Esteras, C., Esteva, J., Bueso, M.C., Cañizares, J., Picó, M.B., Monforte, A.J. and Fernández-Trujillo, J.P. (2021), Transcriptomic analysis of a near-isogenic line of melon with high fruit flesh firmness during ripening. J Sci Food Agric, 101: 754-777, which has been published in final form at https://doi.org/10.1002/jsfa.10688. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.[EN] BACKGROUND A near-isogenic line (NIL) of melon (SC10-2) with introgression in linkage group X was studied from harvest (at firm-ripe stage of maturity) until day 18 of postharvest storage at 20.5 degrees C together with its parental control ('Piel de Sapo', PS). RESULTS SC10-2 showed higher flesh firmness and whole fruit hardness but lower juiciness than its parental. SC10-2 showed a decrease in respiration rate accompanied by a decrease in ethylene production during ripening, both of which fell to a greater extent than in PS. The introgression affected 11 volatile organic compounds (VOCs), the levels of which during ripening were generally higher in SC10-2 than in PS. Transcriptomic analysis from RNA-Seq revealed differentially expressed genes (DEGs) associated with the effects studied. For example, 909 DEGs were exclusive to the introgression, and only 23 DEGs were exclusive to postharvest ripening time. Major functions of the DEGs associated with introgression or ripening time were identified by cluster analysis. About 37 genes directly and/or indirectly affected the delay in ripening of SC10-2 compared with PS in general and, more particularly, the physiological and quality traits measured and, probably, the differential non-climacteric response. Of the former genes, we studied in more detail at least five that mapped in the introgression in linkage group (LG) X, and 32 outside it. CONCLUSION There is an apparent control of textural changes, VOCs and fruit ripening by an expression quantitative trait locus located in LG X together with a direct control on them due to genes presented in the introgression (CmTrpD,CmNADH1,CmTCP15,CmGDSL esterase/lipase, andCmHK4-like) and CmNAC18.This work was funded by grants 11784/PI/09 (Seneca Foundation, Region of Murcia) and Ministry of Economy and Innovation (AGL2010-20858). M Zarid acknowledges an UE-Erasmus predoctoral fellowship, a program coordinated by the University of Murcia in the framework of CMN. Thanks are due to Semillas Fitó SA (Barcelona, Spain), for providing seeds of PS melons and IRTACRAG for the seeds of SC10-2. We acknowledge the assistance of P Varó and his team in CIFEA-Torre Pacheco for crop management, to N Dos-Santos, M Medina, M García-Gutiérrez, A Hakmaoui, E Cuadros, I Canales and AA Escudero (UPCT) for sampling and technical assistance, to SAIT-UPCT for GC-MS analysis, to AG Sifres (COMAV) for RNA extraction, and to CNAG (Barcelona) for professional assistance in RNA-Seq. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.Zarid, M.; García-Carpintero, V.; Esteras Gómez, C.; Esteva, J.; Bueso, MC.; Cañizares Sales, J.; Picó Sirvent, MB.... (2021). Transcriptomic analysis of a near-isogenic line of melon with high fruit flesh firmness during ripening. Journal of the Science of Food and Agriculture. 101(2):754-777. https://doi.org/10.1002/jsfa.10688S7547771012Ríos, P., Argyris, J., Vegas, J., Leida, C., Kenigswald, M., Tzuri, G., … Garcia-Mas, J. (2017). ETHQV6.3 is involved in melon climacteric fruit ripening and is encoded by a NAC domain transcription factor. The Plant Journal, 91(4), 671-683. doi:10.1111/tpj.13596Ezura, H., & Owino, W. O. (2008). Melon, an alternative model plant for elucidating fruit ripening. Plant Science, 175(1-2), 121-129. doi:10.1016/j.plantsci.2008.02.004Guo, X., Xu, J., Cui, X., Chen, H., & Qi, H. (2017). iTRAQ-based Protein Profiling and Fruit Quality Changes at Different Development Stages of Oriental Melon. BMC Plant Biology, 17(1). doi:10.1186/s12870-017-0977-7Chaparro-Torres, L. A., Bueso, M. C., & Fernández-Trujillo, J. P. (2015). Aroma volatiles obtained at harvest by HS-SPME/GC-MS and INDEX/MS-E-nose fingerprint discriminate climacteric behaviour in melon fruit. Journal of the Science of Food and Agriculture, 96(7), 2352-2365. doi:10.1002/jsfa.7350Pech, J. C., Bouzayen, M., & Latché, A. (2008). Climacteric fruit ripening: Ethylene-dependent and independent regulation of ripening pathways in melon fruit. Plant Science, 175(1-2), 114-120. doi:10.1016/j.plantsci.2008.01.003Dahmani-Mardas, F., Troadec, C., Boualem, A., Lévêque, S., Alsadon, A. A., Aldoss, A. A., … Bendahmane, A. (2010). Engineering Melon Plants with Improved Fruit Shelf Life Using the TILLING Approach. PLoS ONE, 5(12), e15776. doi:10.1371/journal.pone.0015776González, M., Xu, M., Esteras, C., Roig, C., Monforte, A. J., Troadec, C., … Picó, B. (2011). Towards a TILLING platform for functional genomics in Piel de Sapo melons. BMC Research Notes, 4(1). doi:10.1186/1756-0500-4-289Yano, R., Nonaka, S., & Ezura, H. (2017). Melonet-DB, a Grand RNA-Seq Gene Expression Atlas in Melon (Cucumis melo L.). Plant and Cell Physiology, 59(1), e4-e4. doi:10.1093/pcp/pcx193Perpiñá, G., Esteras, C., Gibon, Y., Monforte, A. J., & Picó, B. (2016). A new genomic library of melon introgression lines in a cantaloupe genetic background for dissecting desirable agronomical traits. BMC Plant Biology, 16(1). doi:10.1186/s12870-016-0842-0Pereira, L., Ruggieri, V., Pérez, S., Alexiou, K. G., Fernández, M., Jahrmann, T., … Garcia-Mas, J. (2018). QTL mapping of melon fruit quality traits using a high-density GBS-based genetic map. BMC Plant Biology, 18(1). doi:10.1186/s12870-018-1537-5Eduardo, I., Arús, P., & Monforte, A. J. (2005). Development of a genomic library of near isogenic lines (NILs) in melon (Cucumis melo L.) from the exotic accession PI161375. Theoretical and Applied Genetics, 112(1), 139-148. doi:10.1007/s00122-005-0116-yMoreno, E., Obando, J. M., Dos-Santos, N., Fernández-Trujillo, J. P., Monforte, A. J., & Garcia-Mas, J. (2007). Candidate genes and QTLs for fruit ripening and softening in melon. Theoretical and Applied Genetics, 116(4), 589-602. doi:10.1007/s00122-007-0694-yGalpaz, N., Gonda, I., Shem‐Tov, D., Barad, O., Tzuri, G., Lev, S., … Katzir, N. (2018). Deciphering genetic factors that determine melon fruit‐quality traits using RNA ‐Seq‐based high‐resolution QTL and eQTL mapping. The Plant Journal, 94(1), 169-191. doi:10.1111/tpj.13838Saladié, M., Cañizares, J., Phillips, M. A., Rodriguez-Concepcion, M., Larrigaudière, C., Gibon, Y., … Garcia-Mas, J. (2015). Comparative transcriptional profiling analysis of developing melon (Cucumis melo L.) fruit from climacteric and non-climacteric varieties. BMC Genomics, 16(1). doi:10.1186/s12864-015-1649-3Zhang, H., Wang, H., Yi, H., Zhai, W., Wang, G., & Fu, Q. (2016). Transcriptome profiling of Cucumis melo fruit development and ripening. Horticulture Research, 3(1). doi:10.1038/hortres.2016.14Eduardo, I., Arús, P., Monforte, A. J., Obando, J., Fernández-Trujillo, J. P., Martínez, J. A., … van der Knaap, E. (2007). Estimating the Genetic Architecture of Fruit Quality Traits in Melon Using a Genomic Library of Near Isogenic Lines. Journal of the American Society for Horticultural Science, 132(1), 80-89. doi:10.21273/jashs.132.1.80Nimmakayala, P., Tomason, Y. R., Abburi, V. L., Alvarado, A., Saminathan, T., Vajja, V. G., … Reddy, U. K. (2016). Genome-Wide Differentiation of Various Melon Horticultural Groups for Use in GWAS for Fruit Firmness and Construction of a High Resolution Genetic Map. Frontiers in Plant Science, 7. doi:10.3389/fpls.2016.01437Fernández-Trujillo, J. P., Fernández-Talavera, M., Ruiz-León, M., Roca, M. J., & Dos-Santos, N. (2012). AROMA VOLATILES DURING WHOLE MELON RIPENING IN A CLIMACTERIC NEAR-ISOGENIC LINE AND ITS INBRED NON-CLIMACTERIC PARENTS. Acta Horticulturae, (934), 951-957. doi:10.17660/actahortic.2012.934.127Obando-Ulloa, J. M., Moreno, E., García-Mas, J., Nicolai, B., Lammertyn, J., Monforte, A. J., & Fernández-Trujillo, J. P. (2008). Climacteric or non-climacteric behavior in melon fruit. Postharvest Biology and Technology, 49(1), 27-37. doi:10.1016/j.postharvbio.2007.11.004Obando-Ulloa, J. M., Nicolai, B., Lammertyn, J., Bueso, M. C., Monforte, A. J., & Fernández-Trujillo, J. P. (2009). Aroma volatiles associated with the senescence of climacteric or non-climacteric melon fruit. Postharvest Biology and Technology, 52(2), 146-155. doi:10.1016/j.postharvbio.2008.11.007Gonda, I., Bar, E., Portnoy, V., Lev, S., Burger, J., Schaffer, A. A., … Lewinsohn, E. (2010). Branched-chain and aromatic amino acid catabolism into aroma volatiles in Cucumis melo L. fruit. Journal of Experimental Botany, 61(4), 1111-1123. doi:10.1093/jxb/erp390Dos-Santos, N., Bueso, M. C., & Fernández-Trujillo, J. P. (2013). Aroma volatiles as biomarkers of textural differences at harvest in non-climacteric near-isogenic lines of melon. Food Research International, 54(2), 1801-1812. doi:10.1016/j.foodres.2013.09.031Obando, J., Fernández-Trujillo, J. P., Martínez, J. A., Alarcón, A. L., Eduardo, I., Arús, P., & Monforte, A. J. (2008). Identification of Melon Fruit Quality Quantitative Trait Loci Using Near-isogenic Lines. Journal of the American Society for Horticultural Science, 133(1), 139-151. doi:10.21273/jashs.133.1.139Gomes, M. H., Fundo, J., Obando-Ulloa, J. M., Fernández-Trujillo, J. P., & Almeida, D. P. F. (2010). GENETIC BACKGROUND OF QUALITY AND CELL WALL CHANGES IN FRESH-CUT MELONS. Acta Horticulturae, (877), 1011-1018. doi:10.17660/actahortic.2010.877.136Dos-Santos, N., Jiménez-Araujo, A., Rodríguez-Arcos, R., & Fernández-Trujillo, J. P. (2011). Cell Wall Polysaccharides of Near-Isogenic Lines of Melon (Cucumis melo L.) and Their Inbred Parentals Which Show Differential Flesh Firmness or Physiological Behavior. Journal of Agricultural and Food Chemistry, 59(14), 7773-7784. doi:10.1021/jf201155aFernández-Trujillo, J. P., Obando-Ulloa, J. M., Martínez, J. A., Moreno, E., García-Mas, J., & Monforte, A. J. (2008). Climacteric and non-climacteric behavior in melon fruit. Postharvest Biology and Technology, 50(2-3), 125-134. doi:10.1016/j.postharvbio.2008.04.007Fernández-Trujillo, J., Zarid, M., & Bueso, M. (2018). Methodology to Remove Strong Outliers of Non-Climacteric Melon Fruit Aroma at Harvest Obtained by HS-SPME GC-MS Analysis. Separations, 5(2), 30. doi:10.3390/separations5020030AndrewsS FastQC: a quality control tool for high throughput sequence data. Babraham Bioinformatics (2010). Available:http://www.bioinformatics.babraham.ac.uk/projects/fastqc.Kim, D., Langmead, B., & Salzberg, S. L. (2015). HISAT: a fast spliced aligner with low memory requirements. Nature Methods, 12(4), 357-360. doi:10.1038/nmeth.3317Pertea, M., Pertea, G. M., Antonescu, C. M., Chang, T.-C., Mendell, J. T., & Salzberg, S. L. (2015). StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nature Biotechnology, 33(3), 290-295. doi:10.1038/nbt.3122FuJ FrazeeAC Collado‐TorresL JaffeAEandLeekJT Ballgown: flexible isoform‐level differential expression analysis. R package version 2.12.0(2018).Howe, E. A., Sinha, R., Schlauch, D., & Quackenbush, J. (2011). RNA-Seq analysis in MeV. Bioinformatics, 27(22), 3209-3210. doi:10.1093/bioinformatics/btr490MEV Multi experiment viewer. TM4 MeV stand‐alone client(2018).http://mev.tm4.org/#/welcome. Available:https://sourceforge.net/projects/mev-tm4/[5 October 2018].Conesa, A., Gotz, S., Garcia-Gomez, J. M., Terol, J., Talon, M., & Robles, M. (2005). Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics, 21(18), 3674-3676. doi:10.1093/bioinformatics/bti610Paul, V., Pandey, R., & Srivastava, G. C. (2011). The fading distinctions between classical patterns of ripening in climacteric and non-climacteric fruit and the ubiquity of ethylene—An overview. Journal of Food Science and Technology, 49(1), 1-21. doi:10.1007/s13197-011-0293-4Perotti, V. E., Moreno, A. S., & Podestá, F. E. (2014). Physiological aspects of fruit ripening: The mitochondrial connection. Mitochondrion, 17, 1-6. doi:10.1016/j.mito.2014.04.010ARAÚJO, W. L., NUNES-NESI, A., NIKOLOSKI, Z., SWEETLOVE, L. J., & FERNIE, A. R. (2011). Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues. Plant, Cell & Environment, 35(1), 1-21. doi:10.1111/j.1365-3040.2011.02332.xMelo, A. M. P., Bandeiras, T. M., & Teixeira, M. (2004). New Insights into Type II NAD(P)H:Quinone Oxidoreductases. Microbiology and Molecular Biology Reviews, 68(4), 603-616. doi:10.1128/mmbr.68.4.603-616.2004Møller, I. M. (2001). PLANT MITOCHONDRIA AND OXIDATIVE STRESS: Electron Transport, NADPH Turnover, and Metabolism of Reactive Oxygen Species. Annual Review of Plant Physiology and Plant Molecular Biology, 52(1), 561-591. doi:10.1146/annurev.arplant.52.1.561Fatland, B. L., Ke, J., Anderson, M. D., Mentzen, W. I., Cui, L. W., Allred, C. C., … Wurtele, E. S. (2002). Molecular Characterization of a Heteromeric ATP-Citrate Lyase That Generates Cytosolic Acetyl-Coenzyme A in Arabidopsis,. Plant Physiology, 130(2), 740-756. doi:10.1104/pp.008110Sánchez, L. B., Galperin, M. Y., & Müller, M. (2000). Acetyl-CoA Synthetase from the Amitochondriate EukaryoteGiardia lamblia Belongs to the Newly Recognized Superfamily of Acyl-CoA Synthetases (Nucleoside Diphosphate-forming). Journal of Biological Chemistry, 275(8), 5794-5803. doi:10.1074/jbc.275.8.5794Fraser, M. E., James, M. N. G., Bridger, W. A., & Wolodko, W. T. (1999). A detailed structural description of Escherichia coli succinyl-CoA synthetase 1 1Edited by D. Rees. Journal of Molecular Biology, 285(4), 1633-1653. doi:10.1006/jmbi.1998.2324Causse, M. (2008). Genetic background of flavour: the case of the tomato. Fruit and Vegetable Flavour, 229-253. doi:10.1533/9781845694296.4.229Nishimura, C., Ohashi, Y., Sato, S., Kato, T., Tabata, S., & Ueguchi, C. (2004). Histidine Kinase Homologs That Act as Cytokinin Receptors Possess Overlapping Functions in the Regulation of Shoot and Root Growth in Arabidopsis. The Plant Cell, 16(6), 1365-1377. doi:10.1105/tpc.021477Kieber, J. J. (2002). Journal of Plant Growth Regulation, 21(1), 1-2. doi:10.1007/s003440010059Zhang, Z., Jiang, S., Wang, N., Li, M., Ji, X., Sun, S., … Chen, X. (2015). Identification of Differentially Expressed Genes Associated with Apple Fruit Ripening and Softening by Suppression Subtractive Hybridization. PLOS ONE, 10(12), e0146061. doi:10.1371/journal.pone.0146061Girard, A.-L., Mounet, F., Lemaire-Chamley, M., Gaillard, C., Elmorjani, K., Vivancos, J., … Bakan, B. (2012). Tomato GDSL1 Is Required for Cutin Deposition in the Fruit Cuticle. The Plant Cell, 24(7), 3119-3134. doi:10.1105/tpc.112.101055Hayashi, S., Ishii, T., Matsunaga, T., Tominaga, R., Kuromori, T., Wada, T., … Hirayama, T. (2008). The Glycerophosphoryl Diester Phosphodiesterase-Like Proteins SHV3 and its Homologs Play Important Roles in Cell Wall Organization. Plant and Cell Physiology, 49(10), 1522-1535. doi:10.1093/pcp/pcn120Ge, W., Song, Y., Zhang, C., Zhang, Y., Burlingame, A. L., & Guo, Y. (2011). Proteomic analyses of apoplastic proteins from germinating Arabidopsis thaliana pollen. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1814(12), 1964-1973. doi:10.1016/j.bbapap.2011.07.013Rose, J. K. C., Hadfield, K. A., Labavitch, J. M., & Bennett, A. B. (1998). Temporal Sequence of Cell Wall Disassembly in Rapidly Ripening Melon Fruit1. Plant Physiology, 117(2), 345-361. doi:10.1104/pp.117.2.345Daminato, M., Guzzo, F., & Casadoro, G. (2013). A SHATTERPROOF-like gene controls ripening in non-climacteric strawberries, and auxin and abscisic acid antagonistically affect its expression. Journal of Experimental Botany, 64(12), 3775-3786. doi:10.1093/jxb/ert214Lu, W., Mao, L., Chen, J., Han, X., Ren, X., Ying, T., & Luo, Z. (2018). Interaction of abscisic acid and auxin on gene expression involved in banana ripening. Acta Physiologiae Plantarum, 40(3). doi:10.1007/s11738-018-2621-zBarry, C. S., Llop-Tous, M. I., & Grierson, D. (2000). The Regulation of 1-Aminocyclopropane-1-Carboxylic Acid Synthase Gene Expression during the Transition from System-1 to System-2 Ethylene Synthesis in Tomato. Plant Physiology, 123(3), 979-986. doi:10.1104/pp.123.3.979Wang, L., Zhang, X., Wang, L., Tian, Y., Jia, N., Chen, S., … Pang, X. (2017). Regulation of ethylene-responsive SlWRKYs involved in color change during tomato fruit ripening. Scientific Reports, 7(1). doi:10.1038/s41598-017-16851-yZhang, C., Hou, Y., Hao, Q., Chen, H., Chen, L., Yuan, S., … Huang, W. (2015). Genome-Wide Survey of the Soybean GATA Transcription Factor Gene Family and Expression Analysis under Low Nitrogen Stress. PLOS ONE, 10(4), e0125174. doi:10.1371/journal.pone.0125174Sharma, M. K., Kumar, R., Solanke, A. U., Sharma, R., Tyagi, A. K., & Sharma, A. K. (2010). Identification, phylogeny, and transcript profiling of ERF family genes during development and abiotic stress treatments in tomato. Molecular Genetics and Genomics, 284(6), 455-475. doi:10.1007/s00438-010-0580-1Pirrello, J., Prasad, B. N., Zhang, W., Chen, K., Mila, I., Zouine, M., … Bouzayen, M. (2012). Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biology, 12(1). doi:10.1186/1471-2229-12-190Liu, M., Diretto, G., Pirrello, J., Roustan, J., Li, Z., Giuliano, G., … Bouzayen, M. (2014). The chimeric repressor version of an E thylene Response Factor ( ERF ) family member, Sl‐ ERF .B3 , shows contrasting effects on tomato fruit ripening. New Phytologist, 203(1), 206-218. doi:10.1111/nph.12771Jeong, M.-J., & Shih, M.-C. (2003). Interaction of a GATA factor with cis-acting elements involved in light regulation of nuclear genes encoding chloroplast glyceraldehyde-3-phosphate dehydrogenase in Arabidopsis. Biochemical and Biophysical Research Communications, 300(2), 555-562. doi:10.1016/s0006-291x(02)02892-9Tarze, A., Deniaud, A., Le Bras, M., Maillier, E., Molle, D., Larochette, N., … Brenner, C. (2006). GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene, 26(18), 2606-2620. doi:10.1038/sj.onc.1210074Zala, D., Hinckelmann, M.-V., Yu, H., Lyra da Cunha, M. M., Liot, G., Cordelières, F. P., … Saudou, F. (2013). Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport. Cell, 152(3), 479-491. doi:10.1016/j.cell.2012.12.029YANAKA, N. (2007). Mammalian Glycerophosphodiester Phosphodiesterases. Bioscience, Biotechnology, and Biochemistry, 71(8), 1811-1818. doi:10.1271/bbb.70062Zhu, M., Chen, G., Zhou, S., Tu, Y., Wang, Y., Dong, T., & Hu, Z. (2013). A New Tomato NAC (NAM/ATAF1/2/CUC2) Transcription Factor, SlNAC4, Functions as a Positive Regulator of Fruit Ripening and Carotenoid Accumulation. Plant and Cell Physiology, 55(1), 119-135. doi:10.1093/pcp/pct162Jaakola, L., Poole, M., Jones, M. O., Kämäräinen-Karppinen, T., Koskimäki, J. J., Hohtola, A., … Seymour, G. B. (2010). A SQUAMOSA MADS Box Gene Involved in the Regulation of Anthocyanin Accumulation in Bilberry Fruits    . Plant Physiology, 153(4), 1619-1629. doi:10.1104/pp.110.158279Seymour, G. B., Ryder, C. D., Cevik, V., Hammond, J. P., Popovich, A., King, G. J., … Manning, K. (2010). A SEPALLATA gene is involved in the development and ripening of strawberry (Fragaria×ananassa Duch.) fruit, a non-climacteric tissue*. Journal of Experimental Botany, 62(3), 1179-1188. doi:10.1093/jxb/erq360Obando-Ulloa, J. M., Ruiz, J., Monforte, A. J., & Fernández-Trujillo, J. P. (2010). Aroma profile of a collection of near-isogenic lines of melon (Cucumis melo L.). Food Chemistry, 118(3), 815-822. doi:10.1016/j.foodchem.2009.05.068Gaude, N., Nakamura, Y., Scheible, W.-R., Ohta, H., & Dörmann, P. (2008). Phospholipase C5 (NPC5) is involved in galactolipid accumulation during phosphate limitation in leaves of Arabidopsis. The Plant Journal, 56(1), 28-39. doi:10.1111/j.1365-313x.2008.03582.xLi, M., Qin, C., Welti, R., & Wang, X. (2005). Double Knockouts of Phospholipases Dζ1 and Dζ2 in Arabidopsis Affect Root Elongation during Phosphate-Limited Growth But Do Not Affect Root Hair Patterning. Plant Physiology, 140(2), 761-770. doi:10.1104/pp.105.070995Nakamura, Y., Koizumi, R., Shui, G., Shimojima, M., Wenk, M. R., Ito, T., & Ohta, H. (2009). Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation. Proceedings of the National Academy of Sciences, 106(49), 20978-20983. doi:10.1073/pnas.0907173106Nakamura, Y., Awai, K., Masuda, T., Yoshioka, Y., Takamiya, K., & Ohta, H. (2005). A Novel Phosphatidylcholine-hydrolyzing Phospholipase C Induced by Phosphate Starvation in Arabidopsis. Journal of Biological Chemistry, 280(9), 7469-7476. doi:10.1074/jbc.m408799200Tang, Y., Zhang, C., Cao, S., Wang, X., & Qi, H. (2015). The Effect of CmLOXs on the Production of Volatile Organic Compounds in Four Aroma Types of Melon (Cucumis melo). PLOS ONE, 10(11), e0143567. doi:10.1371/journal.pone.0143567Zhang, C., Cao, S., Jin, Y., Ju, L., Chen, Q., Xing, Q., & Qi, H. (2017). Melon13-lipoxygenase CmLOX18 may be involved in C6 volatiles biosynthesis in fruit. Scientific Reports, 7(1). doi

Competencias para el empleo: comunicación y emprendimiento

Depto. de Investigación y Psicología en EducaciónFac. de EducaciónFALSEsubmitte

Aplicación de las nuevas tecnologías en la rehabilitación del lesionado medular

Las nuevas tecnologías se han ido introduciendo como una herramienta más de neurorehabilitación durante los últimos años. Gracias a los últimos desarrollos tecnológicos y sus diferentes aplicaciones, contamos con diferentes dispositivos que facilitan la diversidad de actividades como complemento al tratamiento rehabilitador tradicional. En este artículo se realiza un breve repaso de ellos

Diseño e implementación de una biblioteca digital de recursos para la acción tutorial entre estudiantes universitarios

Memoria ID-207. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2018-2019

On logical relativity

One logic or many? I say—many. Or rather, I say there is one logic for each way of specifying the class of all possible circumstances, or models, i.e., all ways of interpreting a given language. But because there is no unique way of doing this, I say there is no unique logic except in a relative sense. Indeed, given any two competing logical theories T1 and T2 (in the same language) one could always consider their common core, T, and settle on that theory. So, given any language L, one could settle on the minimal logic T0 corresponding to the common core shared by all competitors. That would be a way of resisting relativism, as long as one is willing to redraw the bounds of logic accordingly. However, such a minimal theory T0 may be empty if the syntax of L contains no special ingredients the interpretation of which is independent of the specification of the relevant L-models. And generally—I argue—this is indeed the case

Evaluación de recursos digitales para la acción tutorial entre estudiantes universitarios

Memoria ID-223. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2019-2020