107 research outputs found
Budesonide/Glycopyrrolate/Formoterol for the Management of COPD in a UK Primary Care Population : Real-World Use and Early Medication Success
We thank Johann Castaneda for his contribution to protocol development, analysis and interpretation of data. Dr Ruth B Murray (Medscript NZ Ltd) provided medical writing assistance under the direction of the authors, funded by AstraZeneca.Peer reviewe
Microwave observations of spinning dust emission in NGC6946
We report new cm-wave measurements at five frequencies between 15 and 18GHz
of the continuum emission from the reportedly anomalous "region 4" of the
nearby galaxy NGC6946. We find that the emission in this frequency range is
significantly in excess of that measured at 8.5GHz, but has a spectrum from
15-18GHz consistent with optically thin free-free emission from a compact HII
region. In combination with previously published data we fit four emission
models containing different continuum components using the Bayesian spectrum
analysis package radiospec. These fits show that, in combination with data at
other frequencies, a model with a spinning dust component is slightly preferred
to those that possess better-established emission mechanisms.Comment: submitted MNRA
The National Clinical Assessment Tool for Medical Students in the Emergency Department (NCAT-EM)
Introduction: Clinical assessment of medical students in emergency medicine (EM) clerkships is
a highly variable process that presents unique challenges and opportunities. Currently, clerkship directors use institution-specific tools with unproven validity and reliability that may or may not address competencies valued most highly in the EM setting. Standardization of assessment practices and development of a common, valid, specialty-specific tool would benefit EM educators and students.
Methods: A two-day national consensus conference was held in March 2016 in the Clerkship Directors in Emergency Medicine (CDEM) track at the Council of Residency Directors in Emergency Medicine (CORD) Academic Assembly in Nashville, TN. The goal of this conference was to standardize assessment practices and to create a national clinical assessment tool for use in EM clerkships across the country. Conference leaders synthesized the literature, articulated major themes and questions pertinent to clinical assessment of students in EM, clarified the issues, and outlined the consensus- building process prior to consensus-building activities.
Results: The first day of the conference was dedicated to developing consensus on these key themes in clinical assessment. The second day of the conference was dedicated to discussing
and voting on proposed domains to be included in the national clinical assessment tool. A modified Delphi process was initiated after the conference to reconcile questions and items that did not reach an a priori level of consensus.
Conclusion: The final tool, the National Clinical Assessment Tool for Medical Students in Emergency Medicine (NCAT-EM) is presented here. [West J Emerg Med. 2018;19(1)66-74.
Instability results for the wave equation in the interior of Kerr black holes
We prove that a large class of smooth solutions to the linear wave
equation on subextremal rotating Kerr spacetimes which are
regular and decaying along the event horizon become singular at the Cauchy
horizon. More precisely, we show that assuming appropriate upper and lower
bounds on the energy along the event horizon, the solution has infinite
(non-degenerate) energy on any spacelike hypersurfaces intersecting the Cauchy
horizon transversally. Extrapolating from known results in the
Reissner--Nordstr\"om case, the assumed upper and lower bounds required for our
theorem are conjectured to hold for solutions arising from generic smooth and
compactly supported initial data on a Cauchy hypersurface. This result is
motivated by the strong cosmic censorship conjecture in general relativity
Bayesian analysis of weak gravitational lensing and Sunyaev-Zel'dovich data for six galaxy clusters
We present an analysis of observations made with the Arcminute Microkelvin
Imager (AMI) and the Canada-France-Hawaii Telescope (CFHT) of six galaxy
clusters in a redshift range of 0.16--0.41. The cluster gas is modelled using
the Sunyaev--Zel'dovich (SZ) data provided by AMI, while the total mass is
modelled using the lensing data from the CFHT. In this paper, we: i) find very
good agreement between SZ measurements (assuming large-scale virialisation and
a gas-fraction prior) and lensing measurements of the total cluster masses out
to r_200; ii) perform the first multiple-component weak-lensing analysis of
A115; iii) confirm the unusual separation between the gas and mass components
in A1914; iv) jointly analyse the SZ and lensing data for the relaxed cluster
A611, confirming our use of a simulation-derived mass-temperature relation for
parameterizing measurements of the SZ effect.Comment: 22 pages, 12 figures, 12 tables, published by MNRA
The iCook 4-H Study: An Intervention and Dissemination Test of a Youth/Adult Out-of-School Program
Objective To describe outcomes from intervention and dissemination of iCook 4-H. Design Five-state, community-based participatory research and a randomized, controlled trial followed by a 5-state, nonrandomized dissemination test of the iCook 4-H curriculum with control and treatment groups. Setting Community and university sites. Participants Youths aged 9–10 years and their adult food preparer; 228 dyads in the intervention and 74 dyads in dissemination. Intervention(s) Theoretical frameworks were Social Cognitive Theory and the experiential 4-H learning model. Six 2-hour, biweekly sessions on cooking, eating, and playing together followed by monthly newsletters and boosters until 24 months, expanded to 8 sessions for dissemination. Main Outcome Measure(s) Youth body mass index (BMI) z-scores, measured height and weight, and youth/adult program outcome evaluations surveys. Analysis Linear mixed models, group, time, and group × time interaction for BMI z-score and program outcomes changes. Significance levels = P ≤ .05; interaction term significance = P ≤ .10. Results In intervention, treatment BMI z-scores increased compared with controls based on significant interaction (P = .04). For odds of being overweight or obese at 24 months, there was no significant interaction (P = .18). In dissemination, based on significant interaction, treatment youths increased cooking skills (P = .03) and treatment adults increased cooking together (P = .08) and eating together (P = .08) compared with controls. Conclusions and Implications iCook 4-H program outcomes were positive for mealtime activities of cooking and eating together. The program can be successfully implemented by community educators. The increase in BMI z-scores needs further evaluation for youths in cooking programs
High resolution AMI Large Array imaging of spinning dust sources: spatially correlated 8 micron emission and evidence of a stellar wind in L675
We present 25 arcsecond resolution radio images of five Lynds Dark Nebulae
(L675, L944, L1103, L1111 & L1246) at 16 GHz made with the Arcminute
Microkelvin Imager (AMI) Large Array. These objects were previously observed
with the AMI Small Array to have an excess of emission at microwave frequencies
relative to lower frequency radio data. In L675 we find a flat spectrum compact
radio counterpart to the 850 micron emission seen with SCUBA and suggest that
it is cm-wave emission from a previously unknown deeply embedded young
protostar. In the case of L1246 the cm-wave emission is spatially correlated
with 8 micron emission seen with Spitzer. Since the MIR emission is present
only in Spitzer band 4 we suggest that it arises from a population of PAH
molecules, which also give rise to the cm-wave emission through spinning dust
emission.Comment: accepted MNRA
Follow-up observations at 16 and 33 GHz of extragalactic sources from WMAP 3-year data: I - Spectral properties
We present follow-up observations of 97 point sources from the Wilkinson
Microwave Anisotropy Probe (WMAP) 3-year data, contained within the New
Extragalactic WMAP Point Source (NEWPS) catalogue between declinations of -4
and +60 degrees; the sources form a flux-density-limited sample complete to 1.1
Jy (approximately 5 sigma) at 33 GHz. Our observations were made at 16 GHz
using the Arcminute Microkelvin Imager (AMI) and at 33 GHz with the Very Small
Array (VSA). 94 of the sources have reliable, simultaneous -- typically a few
minutes apart -- observations with both telescopes. The spectra between 13.9
and 33.75 GHz are very different from those of bright sources at low frequency:
44 per cent have rising spectra (alpha < 0.0), where flux density is
proportional to frequency^-alpha, and 93 per cent have spectra with alpha <
0.5; the median spectral index is 0.04. For the brighter sources, the agreement
between VSA and WMAP 33-GHz flux densities averaged over sources is very good.
However, for the fainter sources, the VSA tends to measure lower values for the
flux densities than WMAP. We suggest that the main cause of this effect is
Eddington bias arising from variability.Comment: 12 pages, 13 figures, submitted to MNRA
The iCook 4-H Study: Report on Physical Activity and Sedentary Time in Youth Participating in a Multicomponent Program Promoting Family Cooking, Eating, and Playing Together
Objective To report physical activity and sedentary time outcomes of youth in iCook 4-H. Study Design and Setting iCook 4-H was a 5-state, randomized, control–treatment, family-based childhood obesity prevention intervention promoting cooking, eating, and playing together. Participants and Intervention Youth aged 9–10 years and the main preparer of their meals participated in the 12-week program followed by monthly newsletters and biyearly booster sessions until 24 months. Main Outcome Measure(s) A total of 155 youth were fitted with an Actigraph GT3X+ accelerometer, which they wore for 7 days at baseline and 4, 12, and 24 months to measure mean daily minutes per hour of waking wear time for sedentary time (ST), light physical activity (PA) (LPA), moderate PA, vigorous PA, and moderate to vigorous PA. Self-reported PA was assessed using the Block Kids Physical Activity Screener and additional questions querying for the program goal of the frequency of family actively playing together. Linear mixed models were used to determine differences from baseline to 24 months. Significance was set at P ≤ .05. Results There was a significant (P \u3c .05) group × time interaction for LPA (adjusted interaction B estimate, 95% confidence interval; 0.18 [0.05, 0.30]) and ST (−0.15 [−0.26, −0.04]); ST increased and LPA decreased in the treatment group. There were no differences in other accelerometer-derived PA measures, self-report Block Kids Physical Activity Screener measures, or frequency of family actively playing together at any time point. Conclusions and Implications iCook 4-H was a multicomponent program observing youth aged 9–10 years for 24 months that focused on enhancing cooking skills, mealtime behavior and conversation, and PA through daily family activities. Greater emphasis on developing PA skills, changing environmental factors, and increasing PA both in and after school may be needed
The iCook 4-HStudy: Report on Physical Activity and Sedentary Time in Youth Participating in a Multicomponent Program Promoting Family Cooking, Eating, and Playing Together
Objective: To report physical activity and sedentary time outcomes of youth in iCook 4-H. Study Design and Setting: iCook 4-H was a 5-state, randomized, control−treatment, family-based childhood obesity prevention intervention promoting cooking, eating, and playing together. Participants and Intervention: Youth aged 9−10 years and the main preparer of their meals participated in the 12-week program followed by monthly newsletters and biyearly booster sessions until 24 months. Main Outcome Measure(s): A total of 155 youth were fitted with an Actigraph GT3X+ accelerometer, which they wore for 7 days at baseline and 4, 12, and 24 months to measure mean daily minutes per hour of waking wear time for sedentary time (ST), light physical activity (PA) (LPA), moderate PA, vigorous PA, and moderate to vigorous PA. Self-reported PA was assessed using the Block Kids Physical Activity Screener and additional questions querying for the program goal of the frequency of family actively playing together. Linear mixed models were used to determine differences from baseline to 24 months. Significance was set at P ≤ .05. Results: There was a significant (P \u3c .05) group £ time interaction for LPA (adjusted interaction B estimate, 95% confidence interval; 0.18 [0.05, 0.30]) and ST (-0.15 [-0.26, -0.04]); ST increased and LPA decreased in the treatment group. There were no differences in other accelerometer-derived PA measures, self-report Block Kids Physical Activity Screener measures, or frequency of family actively playing together at any time point. Conclusions and Implications: iCook 4-H was a multicomponent program observing youth aged 9−10 years for 24 months that focused on enhancing cooking skills, mealtime behavior and conversation, and PA through daily family activities. Greater emphasis on developing PA skills, changing environmental factors, and increasing PA both in and after school may be needed
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