42 research outputs found
Dynamic behavior and microstructural properties of cancellous bone
The aim of the presented study is to identify some properties of the dynamic
behavior of the cancellous bone and to identify the link between this
mechanical behavior and the microstructural properties. 7 cylinders of bovine
cancellous bone (diameter 41 mm, thickness 14 mm) were tested in quasi static
loading (0.001 s-1), 8 in dynamic loading (1000 s-1) and 10 in dynamic loading
(1500 s-1) with a confinement system. All the specimens were submitted to
imaging before the tests (pQCT) in order to indentify two microstructural
properties: Bone Volume / Total Volume ? BV/TV ? and Trabeculae Thickness ?
Tb.Th. The behavior of bovine cancellous bone under compression exhibits a
foam-type behavior over the whole range of strain rates explored in this study.
The results show that for the quasi-static tests only the stresses are
correlated with BV/TV. For the unconfined dynamic tests, the yield stress is
correlated to BV/TV and the plateau stress to BV/TV and Tb.Th. For the confined
tests, only the plateau stress is correlated to BV/TV and Tb.Th. The effect of
strain rate is an increase of the yield stress and the plateau stress. The
confinement has an effect on the measured values of compression stresses that
confirms the importance of marrow flow in the overall behavior
Gender differences in the use of cardiovascular interventions in HIV-positive persons; the D:A:D Study
Peer reviewe
EVALUATION DE TROIS TECHNIQUES DE DOSAGE DIRECT DU CHOLESTEROL LDL (DES BIOL. MED.)
GRENOBLE1-BU MĂ©decine pharm. (385162101) / SudocSudocFranceF
Traitement et perspectives de traitement du diabète de type II
BORDEAUX2-BU Santé (330632101) / SudocSudocFranceF
Dynamic behavior and microstructural properties of cancellous bone
International audienceThe aim of the presented study is to identify some properties of the dynamic behavior of the cancellous bone and to identify the link between this mechanical behavior and the microstructural properties. 7 cylinders of bovine cancellous bone (diameter 41 mm, thickness 14 mm) were tested in quasi static loading (0.001 s-1), 8 in dynamic loading (1000 s-1) and 10 in dynamic loading (1500 s-1) with a confinement system. All the specimens were submitted to imaging before the tests (pQCT) in order to indentify two microstructural properties: Bone Volume / Total Volume – BV/TV – and Trabeculae Thickness – Tb.Th. The behavior of bovine cancellous bone under compression exhibits a foam-type behavior over the whole range of strain rates explored in this study. The results show that for the quasi-static tests only the stresses are correlated with BV/TV. For the unconfined dynamic tests, the yield stress is correlated to BV/TV and the plateau stress to BV/TV and Tb.Th. For the confined tests, only the plateau stress is correlated to BV/TV and Tb.Th. The effect of strain rate is an increase of the yield stress and the plateau stress. The confinement has an effect on the measured values of compression stresses that confirms the importance of marrow flow in the overall behavior
Clinopyroxene-melt experiments of Holuhraun basalt, Iceland: implications for magma storage and transport in the crust
International audienc
Developing and Validating an Individual-Level Deprivation Index for Children’s Health in France
Background: Deprivation generates many health inequalities. This has to be taken in account to enhance appropriate access to care. This study aimed to develop and validate a pediatric individual-level index measuring deprivation, usable in clinical practice and in public health. Methods: The French Individual Child Deprivation Index (FrenChILD-Index) was designed in four phases: item generation then reduction using the literature review and expert opinions, and index derivation then validation using a cross-sectional study in two emergency departments. During these last two phases, concordance with a blinded evaluation by an expert enabled us to determine thresholds for two levels of moderate and severe deprivation. Results: The generation and reduction phases retained 13 items. These were administered to 986 children for the derivation and validation phases. In the validation phase, the final 12 items of the FrenChILD-Index showed for moderate deprivation (requiring single specific care for deprived children) a sensitivity of 96.0% [92.6; 98.7] and specificity of 68.3% [65.2; 71.4]. For severe deprivation (requiring a multidisciplinary level of care), the sensitivity was 96.3% [92.7; 100] and specificity was 91.1% [89.2; 92.9]. Conclusions: The FrenChILD-Index is the first pediatric individual-level index of deprivation validated in Europe. It enables clinical practice to address the social determinants of health and meet public health goals
Expanding the spectrum of congenital myopathy linked to recessive mutations in SCN4A
International audienc