460 research outputs found
Influence of intrafamilial abuse in children's change of values towards their parents
The socialization that parents and society exercise on children instills in them a set of values towards parents. Some of these values are not lying, feeling affection for the parents, and wanting to have contact with them. In this work, we attempt to determine whether these values change in the face of intrafamilial abuse. To that end, an incidental sample was used, consisting of 2730 minors aged between 6 to 18 years, who had never suffered abuse. They were asked to put themselves in the place of the main character of a story. The story varied depending on the conditions to be studied: observation and direct suffering or account of the abuse by another, type of abuse (physical or psychological), who perpetrated the abuse (custodian or non-custodial), and who received it (the other custodian or the minor). The results show that, as a rule, children lie to conceal both parents' abusive behavior; they love their parents and want to have contact with them, even in the presence of abuse. Notwithstanding that in the presence of abuse by one of their parents, children still love them and want to have contact with both parents, a significant number of children, however, stop loving them or want to have contact with the abusive parent. These results undermine what is defended by theories like PAS with no scientific evidence, and underline the need to use scientific procedures to test the reliability of minors’ testimony based on the idea that children tell the truth.Die von Eltern und Gesellschaft initiierten Sozialisationsprozesse erziehen Kindern eine Reihe von Werten im Umgang mit ihren Eltern an. Einige dieser Werte sind beispielsweise: nicht zu lügen, eine Zuneigung zu den Eltern zu verspüren und Kontakt zu ihnen haben zu wollen. In dieser wissenschaftlichen Arbeit wird versucht zu untersuchen, ob sich diese Werte bei innerfamilialem Missbrauch verändern. Zu diesem Zweck wurde eine Stichprobe von 2730 Minderjährigen im Alter zwischen 6 und 18 Jahren, die noch nie missbraucht wurden, herangezogen. Sie wurden gebeten, sich in die Hauptfigur einer Geschichte hineinzuversetzen. Die Geschichte variierte je nach den zu untersuchenden Bedingungen: Beobachtung und direktes Erleiden oder Erzählung des Missbrauchs durch andere, Art des Missbrauchs (physisch oder psychisch), wer den Missbrauch begangen hat (erziehungsberechtigter oder nicht erziehungsberechtigter Elternteil) und wer dem Missbrauch ausgesetzt war (der andere Elternteil oder das Kind). Die Ergebnisse zeigen, dass Kinder in der Regel lügen, wenn es darum geht das missbräuchliche Verhalten von einem der beiden Elternteile zu verbergen. Sie lieben ihre Eltern und möchten Kontakt zu ihnen haben, selbst im Falle von Missbrauch. Ungeachtet dessen, das einige Kinder bei Misshandlung durch einen ihrer Elternteile, beide Eltern immer noch lieben und Kontakt zu ihnen haben wollen, hört eine signifikante Anzahl von Kinder auf, den missbrauchenden Elternteil zu lieben oder Kontakt zu ihm haben zu wollen. Diese Ergebnisse falsifizieren, was von Theorien wie PAS ohne wissenschaftliche Beweise behauptet wird und unterstreichen die Notwendigkeit der Verwendung wissenschaftlicher Verfahren, die auf der Idee fußen, dass Kinder die Wahrheit sagen, zur zuverlässigen Untersuchung der Zeugenaussagen von Kindern
Semantic Context Forests for Learning-Based Knee Cartilage Segmentation in 3D MR Images
The automatic segmentation of human knee cartilage from 3D MR images is a
useful yet challenging task due to the thin sheet structure of the cartilage
with diffuse boundaries and inhomogeneous intensities. In this paper, we
present an iterative multi-class learning method to segment the femoral, tibial
and patellar cartilage simultaneously, which effectively exploits the spatial
contextual constraints between bone and cartilage, and also between different
cartilages. First, based on the fact that the cartilage grows in only certain
area of the corresponding bone surface, we extract the distance features of not
only to the surface of the bone, but more informatively, to the densely
registered anatomical landmarks on the bone surface. Second, we introduce a set
of iterative discriminative classifiers that at each iteration, probability
comparison features are constructed from the class confidence maps derived by
previously learned classifiers. These features automatically embed the semantic
context information between different cartilages of interest. Validated on a
total of 176 volumes from the Osteoarthritis Initiative (OAI) dataset, the
proposed approach demonstrates high robustness and accuracy of segmentation in
comparison with existing state-of-the-art MR cartilage segmentation methods.Comment: MICCAI 2013: Workshop on Medical Computer Visio
Relocating Underwater Features Autonomously Using Sonar-Based SLAM
This paper describes a system for reacquiring features of interest in a shallow-water ocean environment, using autonomous underwater vehicles (AUVs) equipped with low-cost sonar and navigation sensors. In performing mine countermeasures, it is critical to enable AUVs to navigate accurately to previously mapped objects of interest in the water column or on the seabed, for further assessment or remediation. An important aspect of the overall system design is to keep the size and cost of the reacquisition vehicle as low as possible, as it may potentially be destroyed in the reacquisition mission. This low-cost requirement prevents the use of sophisticated AUV navigation sensors, such as a Doppler velocity log (DVL) or an inertial navigation system (INS). Our system instead uses the Proviewer 900-kHz imaging sonar from Blueview Technologies, which produces forward-looking sonar (FLS) images at ranges up to 40 m at approximately 4 Hz. In large volumes, it is hoped that this sensor can be manufactured at low cost. Our approach uses a novel simultaneous localization and mapping (SLAM) algorithm that detects and tracks features in the FLS images to renavigate to a previously mapped target. This feature-based navigation (FBN) system incorporates a number of recent advances in pose graph optimization algorithms for SLAM. The system has undergone extensive field testing over a period of more than four years, demonstrating the potential for the use of this new approach for feature reacquisition. In this report, we review the methodologies and components of the FBN system, describe the system's technological features, review the performance of the system in a series of extensive in-water field tests, and highlight issues for future research.QC 20130822</p
Comparison of individual and pooled samples for quantification of antimicrobial resistance genes in swine feces by high-throughput qPCR
Effect of variation in oxytetracycline treatment of Lawsonia intracellularis diahrea in nursery pigs on treatment-efficacy and resistance development
A Danish research project, MINIRESIST, investigated the consequences of varying doses and treatment strategies for oxytetracycline treatment of Lawsonia intracellularis diarrhea in nursery pigs. Batches of nursery pigs in five herds were randomly allocated to one of five treatment protocols (batch treatment orally with high, normal and low doses; penwise treatment with normal dose and injection treatment with normal dose). Outcomes, in terms of reduction of L. intracellularis determined by qPCR, growth rate and fecal dry matter content (determined on 30 pigs per batch in 61 batches), and levels of tetracyclineresistant coliforms, and quantification of resistance genes in intestinal content (determined on 15 pigs per batch in 80 batches), were determined and analyzed statistically
Type VI secretion: a beginner's guide
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and the secreted VgrG and Hcp proteins. Type VI secretion is clearly a key virulence factor for some important pathogenic bacteria and has been implicated in the translocation of a potential effector protein into eukaryotic cells by at least one organism (Vibrio cholerae). However, type VI secretion systems (T6SSs) are widespread in nature and not confined to known pathogens. In accordance with the general rule that the expression of protein secretion systems is tightly regulated, expression of type VI secretion is controlled at both transcriptional and post-transcriptional levels
Early mortality from colorectal cancer in England: a retrospective observational study of the factors associated with death in the first year after diagnosis
Background: The United Kingdom performs poorly in international comparisons of colorectal cancer survival with much of the deficit owing to high numbers of deaths close to the time of diagnosis. This retrospective cohort study investigates the patient, tumour and treatment characteristics of those who die in the first year after diagnosis of their disease. Methods: Patients diagnosed with colon (n=65,733) or rectal (n=26,123) cancer in England between 2006 and 2008 were identified in the National Cancer Data Repository. Multivariable logistic regression was used to investigate the odds of death within 1 month, 1-3 months and 3-12 months after diagnosis. Results: In all, 11.5% of colon and 5.4% of rectal cancer patients died within a month of diagnosis: this proportion decreased significantly over the study period. For both cancer sites, older age, stage at diagnosis, deprivation and emergency presentation were associated with early death. Individuals who died shortly after diagnosis were also more likely to have missing data about important prognostic factors such as disease stage and treatment. Conclusion: Using routinely collected data, at no inconvenience to patients, we have identified some important areas relating to early deaths from colorectal cancer, which merit further research
Pengaruh Model Cooperative Learning Metode Two Stay Two Stray (TSTS) dan Numbered Head Together (NHT) terhadap Pemahaman Konsep Akuntansi Siswa ditinjau dari Kemampuan Awal Siswa : studi quasi eksperimen pada materi laporan keuangan perusahaan jasa mata pelajaran siklus akuntansi perusahaan jasa kelas X SMK Negeri 1 Kota Tasikmalaya tahun Ajaran 2014/2015
Penelitian ini dilakukan untuk melihat pengaruh model cooperative learning metode TSTS dan NHT terhadap pemahaman konsep akuntansi ditinjau dari kemampuan awal siswa dalam mata pelajaran akuntansi kelas X Akuntansi SMKN 1 Kota Tasikmalaya. Metode yang digunakan adalah quasi eksperimen dengan pengambilan sampel cluster random sampling yaitu kelas X-Ak 1 dan X-Ak 3. Kemampuan awal setiap kelas dibagi menjadi dua kategori, yaitu kemampuan awal tinggi dan kemampuan awal rendah. Data penelitian dikumpulkan melalui tes tulis yaitu tes kemampuan awal, pre test, dan pos test. Uji Hipotesis menggunakan uji anova between subject design faktorial 2x2. Hasil penelitian menunjukan ada pengaruh metode pembelajaran NHT dan TSTS terhadap pemahaman konsep akuntansi. Ada pengaruh kemampuan awal terhadap pemahaman konsep akuntansi. Ada pengaruh dan interaksi penggunaan metode TSTS dan NHT terhadap peningkatan pemahaman konsep akuntansi ditinjau dari kemampuan awal. Pemahaman konsep siswa yang memiliki kemampuan awal tinggi dengan metode NHT lebih tinggi dari penggunaan metode TSTS dengan kemampuan awal yang sama. Peningkatan pemahaman konsep siswa dengan kemampuan awal rendah metode TSTS lebih baik dari metode NHT.
This research was conducted to see the effect of cooperative learning model of Two Stay Two Stray method and Numbered Head Together method toward the understanding of accounting concepts seen from the student’s prior knowledge.The research method was is quasi experimental with cluster random sampling in class X-Ak 1 and X-Ak 3. Prior Knowledge of each class is divided into two categories, namely high prior knowledge and low prior knowledge. The instrument used in this research was tests, was prerequisite test, pre test and post test. Hypothesis test using ANOVA test between subject 2x2 factorial design.The findings of this research are: there is the influence of the use of methods TSTS and NHT toward the increase of the understanding of accounting concepts. There is also the influence of the prior knowledge toward the increase of the understanding of accounting concepts. Moreover an effect of interaction between TSTS method and NHT method with the student’s prior knowledge toward the increase of the understanding of accounting concepts. The use of NHT method and TSTS method increased the understanding of the concept of students who have a high prior knowledge. Meanwhile, the use of TSTS method is better than NHT method in improving student comprehension with low prior knowledge
Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome, a devastating inflammatory condition characterized by neutrophil recruitment and accumulation of protein-rich edema fluid causing impaired lung function. We hypothesized that targeting the intracellular protein myeloid cell leukemia 1 (Mcl-1) by a cyclin-dependent kinase inhibitor (AT7519) or a flavone (wogonin) would accelerate neutrophil apoptosis and resolution of established inflammation, but without detriment to bacterial clearance. Mcl-1 loss induced human neutrophil apoptosis, but did not induce macrophage apoptosis nor impair phagocytosis of apoptotic neutrophils. Neutrophil-dominant inflammation was modelled in mice by either endotoxin or bacteria (Escherichia coli). Downregulating inflammatory cell Mcl-1 had anti-inflammatory, pro-resolution effects, shortening the resolution interval (R(i)) from 19 to 7 h and improved organ dysfunction with enhanced alveolar–capillary barrier integrity. Conversely, attenuating drug-induced Mcl-1 downregulation inhibited neutrophil apoptosis and delayed resolution of endotoxin-mediated lung inflammation. Importantly, manipulating lung inflammatory cell Mcl-1 also accelerated resolution of bacterial infection (R(i); 50 to 16 h) concurrent with enhanced bacterial clearance. Therefore, manipulating inflammatory cell Mcl-1 accelerates inflammation resolution without detriment to host defense against bacteria, and represents a target for treating infection-associated inflammation
Fabrication and Properties of Ag-nanoparticles Embedded Amorphous Carbon Nanowire/CNT Heterostructures
Carbon nanotubes were subjected to doping with an energetic Ag ion beam, and the carbon nanotubes on the top of the array were transformed into amorphous carbon nanowires with embedded Ag-nanoparticles. The field emission characteristics of these nanowires were investigated. The minimum turn-on and threshold fields were 0.68 and 1.09 V/μm, respectively, which were lower than those of the as-grown carbon nanotubes. This was probably because Ag-nanoparticles embedded in the carbon nanowires reduced the effective work function from 4.59 to 4.23 eV. Large doping amounts produced serious structural damage at the top of the nanowires and impaired the field emission characteristics
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