Estado del arte del programa de implante coclear del Hospital Dr. Luis Calvo Mackenna

Tesis (Fonoaudiología)En Chile, desde hace 24 años se han estado realizando cirugías de implante coclear. Por consiguiente, el año 2008 se crea un convenio entre el Programa de Salud del Estudiante de la JUNAEB y el Hospital Dr. Luis Calvo Mackenna, formalizando un programa de implantes auditivos, es por esto por lo que surge la pregunta: ¿Cuán efectivo es el programa de implante coclear del Hospital Dr. Luis Calvo Mackenna? De la pregunta de investigación surgen los siguientes objetivos: en primer lugar, determinar la efectividad del programa de implante coclear dentro del Hospital Dr. Luis Calvo Mackenna durante los últimos 10 años. Lo anterior mediante la comparación de resultados antes y después de la implantación considerando variables como PTP, Categoría de Percepción Acústica y Escolaridad. La metodología utilizada para el cumplimiento de estos objetivos fue la revisión de fichas clínicas de los usuarios pertenecientes al programa, extrayendo las variables antes mencionadas. Además de revisar la literatura compatible para una discusión crítica de los resultados. La muestra final estuvo constituida por 37 usuarios, arrojando como resultado diferencias estadísticamente significativas en la mayoría de estos, mostrando avances en el PTP y Categoría de Percepción Acústica, repercutiendo de manera positiva en la reinserción escolar. Se demostró la efectividad del programa con los resultados propuestos, además se incluyen los alcances de generar estudios que integren distintas instituciones para mejorar la salud de los usuarios, así también las limitaciones de esta

Construcción de significados en la comunidad educativa de la Escuela Orlando Peña Carvajal en relación al tiempo libre

Tesis (Terapia Ocupacional)La presente investigación es el medio para obtener el título de Terapeutas Ocupacionales de la Universidad Andrés Bello Viña del mar. Una de las áreas de esta disciplina se centra en educación, por lo que nuestro foco de interés es contextualizar, averiguar e interpretar las concepciones y experiencias de la comunidad educativa en relación al tiempo libre y cómo estas repercuten en el bienestar y desarrollo de los niño/as de la escuela Orlando Peña Carvajal ubicada en la comuna de Viña del mar, Región de Valparaíso, Chile. El lineamiento que guía esta investigación comienza con las problemáticas identificadas por lo/as investigadores, priorizando y destacando las experiencias de lo/as niño/as en el área educativa, desde una mirada crítica tanto del contexto social como del contexto educativo, continuando con la relevancia disciplinar que implica ampliar la mirada de Terapia Ocupacional en educación, dando énfasis al actual rol de un terapeuta ocupacional en ámbitos educativos y cómo este podría potenciarse. Además,se considera el estado del arte el cual contiene y contrasta investigaciones de diversas disciplinas que son un aporte al presente seminario de investigación. Lo mencionado anteriormente permite formular la pregunta de investigación y planteamiento de objetivos. Siendo la pregunta ¿Cuáles son los significados que construye la comunidad educativa de la escuela Orlando Peña Carvajal de Viña del Mar, en relación al tiempo libre existente en el contexto escolar para el desarrollo y bienestar infantil?, el objetivo general comprender los significados que construye la comunidad educativa perteneciente a la Escuela Orlando Peña Carvajal de Viña del Mar, en relación al tiempo libre existente en el contexto escolar para el desarrollo y bienestar infantil con objetivos específicos como conocer el significado que construyen sobre el tiempo libre en el contexto escolar la comunidad educativa pertenecientes a la Escuela Orlando Peña Carvajal de Viña del Mar, analizar la concepción de sujetos que emerge en torno a la experiencia de ser niño/a en el contexto escolar y su relación con el bienestar y desarrollo infantil, en la comunidad educativa de la Escuela Orlando Peña Carvajal de Viña del Mar y contextualizar socio histórica y culturalmente los significados construidos por la comunidad educativa del establecimiento, en relación al tiempo libre en el contexto escolar y la concepción de sujeto que emerge en torno a la experiencia de ser niño/a..

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Healing

Our film is based on our one word: Healing. We believe that healing is an important part of our community. When the community goes through a tough or difficult time, healing is a critical part of getting past the obstacles that we encounter in our lives. Our film revolves around a group of classmates. They all go to a Tea Talk on healing in the multicultural center on campus. The characters recall flashbacks of experiences when they were either hurt in the past or of a time they hurt someone else. Throughout the talk, they come to realize that even through the pain they must be able to heal in order to get on with their lives. Our film addresses current social problems and conflicts that we see occurring in our society today, including: Islamophobia, LGBT+ community issues, racial prejudices (interracial couples), and foster care. The relationships and friendships in the film are representative of these issues and used to show how we as a community can be able to heal and fix the problems we are facing today

Healing

Our film is based on our one word: Healing. We believe that healing is an important part of our community. When the community goes through a tough or difficult time, healing is a critical part of getting past the obstacles that we encounter in our lives. Our film revolves around a group of classmates. They all go to a Tea Talk on healing in the multicultural center on campus. The characters recall flashbacks of experiences when they were either hurt in the past or of a time they hurt someone else. Throughout the talk, they come to realize that even through the pain they must be able to heal in order to get on with their lives. Our film addresses current social problems and conflicts that we see occurring in our society today, including: Islamophobia, LGBT+ community issues, racial prejudices (interracial couples), and foster care. The relationships and friendships in the film are representative of these issues and used to show how we as a community can be able to heal and fix the problems we are facing today

Synthesis and characterization of the first cyrhetrenyl-appended calix[4]arene macrocycle and its application as an electrochemical sensor for the determination of Cu(II) in bivalve mollusks using square wave anodic stripping voltammetry

An electrochemical sensor for the determination of Cu(II) in bivalve mollusks using a glassy carbon electrode modified with p-tert-butylcalix [4]arene-bis-cyrhetrenylimine (Cy2(Calix [4])) by square wave anodic stripping voltammetry (SWASV) has been developed. The organometallic compound was synthesized from cyrhetrene-carboxaldehyde and 25,26-bis-(2-aminoethoxy)-26,28-dihydrocalix [4]arene through a condensation reaction. Metalloligand (Cy2(Calix [4])) was characterized by FT-IR and 1H-13C 2D NMR spectroscopies and monocrystal X-ray diffraction and was obtained as a single isolated isomer (E). The optimum chemical and electrochemical conditions for the modified electrode were optimized and the methodology was applied in different samples of bivalve mollusks with satisfactory results. A cooperative effect between the organometallic fragment and the calixarene macrocycle improves the preconcentration capacity of the electrochemical sensor, creating a new opportunity to perform rapid and sensitive analyses in the detection of copper in marine resources

Enhanced removal of mercury and lead by a novel and efficient surface-functionalized imogolite with nanoscale zero-valent iron material

A novel hybrid nanomaterial, nanoscale zero-valent iron (nZVI)-grafted imogolite nanotubes (Imo), was synthesized via a fast and straightforward chemical procedure. The as-obtained nanomaterial (Imo-nZVI) was characterized using transmission electron microscopy (TEM), electrophoretic mobility (EM), and vibrating sample magnetometry (VSM). The prepared Imo-nZVI was superparamagnetic at room temperature and could be easily separated by an external magnetic field. Sorption batch experiments were performed for single- and multicomponent systems and demonstrated that Hg2+ and Pb2+ could be quantitatively adsorbed at pH 3.0. For multicomponent systems, maximum adsorption capacities of 61.6 mg·g−1 and 76.9 mg·g−1 were obtained for Hg2+ and Pb2+ respectively. It was observed that the functional groups in Imo-nZVI interact preferentially with analytes according to the Misono softness parameter. The higher performance of Imo-nZVI compared with Imo and nZVI is related to the increased number of adsorption sites in the functionalized nanomaterial. The sorption equilibrium data obeyed the Langmuir model, while kinetic studies demonstrated that the sorption processes of Hg2+ and Pb2+ followed the pseudo-second-order model. This study suggests that the Imo-nZVI composite can be used as a promising sorbent to provide a simple and fast separation method to remove Hg and Pb ions from contaminated water.Fil: Martinis, Estefanía Mabel. Universidad Nacional de Cuyo. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; ArgentinaFil: Denardin, Juliano Casagrande. Universidad de Santiago de Chile; ChileFil: Calderón, Raul. Universidad Bernardo O’Higgins; ChileFil: Flores, Cristóbal. Universidad de Santiago de Chile; ChileFil: Manquián Cerda, Karen. Universidad de Santiago de Chile; ChileFil: Maldonado, Tamara. Universidad de Santiago de Chile; ChileFil: Arancibia Miranda, Nicolás. Universidad de Santiago de Chile; Chil

Tubulin is retained throughout the human hematopoietic/erythroid cell differentiation process and plays a structural role in sedimentable fraction of mature erythrocytes

We investigated the properties of tubulin present in the sedimentable fraction (“Sed-tub”) of human erythrocytes, and tracked the location and organization of tubulin in various types of cells during the process of hematopoietic/erythroid differentiation. Sed-tub was sensitive to taxol/nocodazole (drugs that modify microtubule assembly/disassembly), but was organized as part of a protein network rather than in typical microtubule form. This network had a non-uniform “connected-ring” structure, with tubulin localized in the connection areas and associated with other proteins. When tubulin was eliminated from Sed-tub fraction, this connected-ring structure disappeared. Spectrin, a major protein component in Sed-tub fraction, formed a complex with tubulin. During hematopoietic differentiation, tubulin shifts from typical microtubule structure (in pro-erythroblasts) to a disorganized structure (in later stages), and is retained in reticulocytes following enucleation. Thus, tubulin is not completely lost when erythrocytes mature; it continues to play a structural role in the Sed-tub fraction.Fil: Nigra, Ayelén Denise. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Santander, Verónica Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Dircio Maldonado, Roberto. MSS National Medical Center; MéxicoFil: Amaiden, Marina Rafaela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Monesterolo, Noelia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Flores Guzmán, Patricia. MSS National Medical Center; MéxicoFil: Muhlberger, Tamara. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Rivelli Antonelli, Juan Franco. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Campetelli, Alexis Nazareno. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Mayani, Héctor. MSS National Medical Center; MéxicoFil: Casale, Cesar Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentin