Famílias com filhos com NEE: a coparentalidade, a coesão e a adaptabilidade como promotores de resiliência

O nascimento de uma criança é uma etapa especial na vida de uma família. É considerada uma das fases mais complexas do ciclo vital da família, uma vez que requer por parte desta capacidade de adaptação para lidar com a integração de um novo membro no seu seio. O nascimento de um filho com Necessidades Educativas Especiais (NEE), implica não só adaptação familiar, como também aceitação, sendo que esta situação pode fortalecer as relações familiares ou pelo contrário desintegrá-las. Para que exista uma adaptação saudável do novo indivíduo na família, a coparentalidade, a coesão, a adaptabilidade e a resiliência, podem facilitar a dinâmica familiar. Como objetivo geral pretende-se analisar a coparentalidade, a coesão, a adaptabilidade e a resiliência em famílias com filhos com NEE. Mais especificamente pretende-se com a presente investigação averiguar de que forma a coparentalidade, a coesão e a adaptabilidade, se comportam como promotores de resiliência nas famílias com filhos com NEE. Participaram no estudo, descritivo e correlacional, 78 sujeitos, sendo 36 pais e 42 mães com filhos com NEE, com idades compreendidas entre os 24 e os 68 anos (M = 42,46; DP = 9,979). Com a aplicação de um Questionário Sócio-demográfico, um Questionário da Coparentalidade, a Escala de Avaliação da Adaptabilidade e Coesão Familiar (FACES III) e a Family Resilience Assessement Scale (FRAS), os resultados obtidos revelam que a maioria das famílias acabou por desenvolver resiliência. Os dados permitem ainda comprovar que, a coparentalidade, a coesão e a adaptabilidade destas famílias contribuem para a promoção de resiliência, sendo a coparentalidade a variável que mais contribui. Face aos resultados obtidos constata-se, desta forma, que estes pais com filhos com NEE dispõem de mecanismos que os ajudam a enfrentar situações de crise, advindas da presença de um filho com NEE, equilibrando a dinâmica familiar.The birth of a new child is a very special stage in the life of the families. It's considered one of the most complex phases of the life cycle. It requires adaptive capacity from the families to correctly deal with a new member's integration. The birth of a child with Special Educational Needs (SEN) implies not only family adaptation but also acceptance. Those can strengthen family relationships or disintegrate them. In order to guarantee a healthy adaptability to the new member with special needs, co-parenting, cohesion, adaptability, and resilience will improve the Family dynamic. The main purpose of this investigation is to analyze co-parenting, the cohesion, adaptability and resilience in families with children with SEN. We intend to investigate how co-parenting, cohesion and adaptability behave as promoters of resilience in families with children with SEN. A total of 78 subjects participated in the descriptive and correlate study, 36 parents and 42 mothers with children with SEN, aged between 24 to 68 years old (M = 42.46, SD = 9.979). With an application of a Socio-Demographic Questionnaire, a Co-parenting Questionnaire, a Family Adaptability and Cohesion Assessment Scale (FACES III) and a Family Resilience Assessment Scale (FRAS), the results obtained reveal that most families have developed resilience. The results also show that the co-parenting, cohesion and the adaptability of these families contribute to the promotion of resilience, with co-parenting being the variable that contributes the most. Thus, taking into account the obtained results, we conclude that the parents who have children with SEN have tools to help them dealing with crisis situations by balancing family dynamics

Consumo de álcool numa amostra portuguesa em idade

É objetivo deste estudo caraterizar e explorar o consumo de álcool (cerveja, vinho e bebidas brancas) numa amostra portuguesa de 68 indivíduos em idade adulta jovem, em função das variáveis sociodemográficas género e idade. Constataram-se percentagens de consumo superiores a 50%, na globalidade da amostra (51,5%), no género masculino (70%) e no grupo etário 22-45 anos (55,6%). No consumo por tipo de bebida, registam-se valores mais elevados no vinho, seguido de cerveja e finalmente de bebidas brancas, no grupo etário mais novo (17- 22 anos), enquanto nos mais velhos (≥22 anos) a cerveja passou a ocupar o primeiro lugar no consumo. Verificaram-se diferenças de género com consumo mais elevado nos masculinos e uma igualdade estatística em função da idade, apesar de percentagens superior de consumo nos mais velhos (≥22 anos). A gravidade do problema em termos de saúde pública exige intervenção precoce, estruturada e integrada, assim como um trabalho educativo contínuo.Abstract: This study aimed to characterize and explore alcohol consumption (beer, wine and spirits) in a Portuguese sample of 68 individuals in early adulthood, according to sociodemographic variables gender and age. Consumption were noted in percentages exceeding 50% in the overall sample (51.5%), in males (70%) and in the age group 22-45 years (55.6%). As regards the type of beverage, highest values were verified in wine, beer and followed finally by spirits, in the youngest age group (17-22 years), while in older (≥22 years) beer occupied the first place in consumption. Gender differences were recorded with greater male consumption. There were no age differences, despite higher rates of consumption in older (≥22 years). The severity of the problem in terms of public health requires early, structured and integrated interventions, as well as an ongoing educational work

Estratégias pedagógicas, planejamento e construção de Objetos de Aprendizagem para uso pedagógico

Este artigo descreve como a perspectiva teórica que fundamenta os objetos deaprendizagem, influencia diretamente as estratégias pedagógicas, planejamento e uso de umobjeto de aprendizagem na prática pedagógica. Os resultados apresentados são fruto de umapesquisa de Mestrado, do Programa de pós-graduação em Educação na linha de pesquisaInformática na Educação da Universidade Federal do Rio Grande do Sul. Através destabuscava-se inventariar quais estratégias pedagógicas são planejadas e usadas por professores nouso do objeto de aprendizagem “Nós no mundo”. Foram analisados estratégias descritas nosplanejamentos por professores do curso de extensão Oficina de Formação de Professores,realizado pelas pesquisadoras no Centro Interdisciplinar de Novas Tecnologias na Educação

Effect of chronic exercise on fluoride metabolism in fluorosis-susceptible mice exposed to high fluoride

Abstract The present study investigated the effect of chronic exercise on fluoride (F) metabolism in fluorosis-susceptible mice exposed to high-F and explored the relationship between F concentrations in bone and plasma. Thirty male mice were randomised into three groups: Group I (No-F, No-Exercise), Group II (50 ppmF, No-Exercise), Group III (50 ppmF, Exercise). Body weight and physical performance of all mice were measured at baseline and end of experiment. F concentrations of plasma and bone were measured at the end of experiment. Mean plasma F concentration was significantly higher (p < 0.001) in Groups II and III compared with Group I. Mean bone F concentration was also significantly higher (p < 0.01) in Groups II and III compared with Group I. There was a significant correlation (p = 0.01, r = 0.54) between F concentration of plasma and bone. Mean body weight of Group I mice was significantly higher than Group II (p < 0.001) and Group III (p = 0.001) mice at the end of the experiment. This study, which provides the first data on the effect of chronic exercise on F metabolism in fluorosis-susceptible mice, suggests no effect of chronic exercise on F in plasma and bone. However, exposure to high-F resulted in lower body weight and exercise capacity in mice

Effect of Physical Exercise and Genetic Background on Glucose Homeostasis and Liver/Muscle Proteomes in Mice.

We compared the parameters related to glucose homeostasis, and liver and muscle proteomes in fluorosis-susceptible (A/J; S) and fluorosis-resistant (129P3/J; R) mice in response to fluoride (F) exposure and exercise. Ninety male mice (45 R-mice and 45 S-mice) were randomized into three groups: (SI; RI) No-F, No-Exercise, (SII; RII) 50 ppm F, No-Exercise, (SIII; RIII) 50 ppm F, Exercise. Overall, mean F concentrations in the plasma and femur were significantly higher in R-mice compared with S-mice. In R-mice, exercise resulted in an increase in F accumulation in the femur. In S-mice, the mean plasma glucose level was significantly higher in Group II compared with Groups I and III. There was an increase in liver proteins involved in energy flux and antioxidant enzymes in non-exercise groups (I, II) of S-mice in comparison with the corresponding groups of R-mice. The results also showed a decrease in muscle protein expression in Group I S-mice compared with their R-mice counterparts. In conclusion, the findings suggest an increased state of oxidative stress in fluorosis-susceptible mice that might be exacerbated by the treatment with F. In addition, fluorosis-susceptible mice have plasma glucose levels higher than fluorosis-resistant mice on exposure to F, and this is not affected by exercise

Explorando estratégias pedagógicas através de “Nós no mundo”

Este artigo descreve o projeto de pesquisa de Mestrado de um grupo de pesquisa da Universidade Federal do Rio Grande do Sul, buscando inventariar quais estratégias pedagógicas são planejadas e usadas quando professores das séries iniciais do Ensino Fundamental utilizam o objeto de aprendizagem “Nós no mundo”. Será mostrado o objeto de aprendizagem em questão, assim como algumas estratégias pensadas a partir do uso deste objeto. Também serão apresentados dados da pesquisa-piloto realizada com um grupo de professores da rede particular de ensino

Association of urinary 90 kDa angiotensin- converting enzyme with family history of hypertension and endothelial function in normotensive individuals

We described angiotensin-I-converting enzyme (ACE) isoforms with molecular masses of 190, 90, and 65 kDa in the urine of normotensive offspring of hypertensive subjects. Since they did not appear in equal amounts, we suggested that 90 kDa ACE might be a marker for hypertension. We evaluated the endothelial response in normotensive offspring with or without family history of hypertension and its association with the 90 kDa ACE in urine. Thirty-five normotensive subjects with a known family history of hypertension and 20 subjects without a family history of hypertension, matched for age, sex, body weight, and blood pressure, were included in the study. Endothelial function was assessed by ultrasound and a sample of urine was collected for determination of ACE isoforms. In the presence of a family history of hypertension and detection of 90 kDa ACE, we noted a maximal flow mediated dilation of 12.1 ± 5.0 vs 16.1 ± 6.0% in those without a previous history of hypertension and lacking urinary 90 kDa ACE (P < 0.05). In subjects with a family history of hypertension and presenting 90 kDa ACE, there were lower levels of HDL-cholesterol (P < 0.05) and higher levels of triglycerides (P < 0.05). Subjects with 90 kDa ACE irrespective of hypertensive history presented a trend for higher levels of triglycerides and HDL-cholesterol (P = 0.06) compared to subjects without 90 kDa ACE. Our data suggest that the 90 kDa ACE may be a marker for hypertension which may be related to the development of early atherosclerotic changes.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de MedicinaFundação Oswaldo Ramos Universidade Federal de São Paulo (UNIFESP) e Hospital do Rim e Hipertensão Departamento de RadiologiaUNIFESP, EPM, Depto. de MedicinaFundação Oswaldo Ramos UNIFESP, e Hospital do Rim e Hipertensão Depto. de RadiologiaSciEL

Epidemiological evaluation and survival of children with acute myeloid leukemia

Objective: This study aims to describe the epidemiological characteristics and survival rates of children with acute myeloid leukemia treated in hospitals in southern Brazil and compare them with international data. Methods: A multicenter cohort study was conducted with retrospective data collection of all new patients with acute myeloid leukemia under 18 treated at five referral centers in pediatric hematology-oncology in southern Brazil between January 2005 and December 2015. Results: Of the 149 patients with acute myeloid leukemia, 63.0% (n = 94) were male. The median age at diagnosis was 10.5 years (range 0-18 years) and 40.3% (n = 60) had a white blood cell count below 50,000/mm2. The most common Franco-American-British (FAB) subtype was M3 (n = 43, 28.9%). Nine (6.0%) patients had central nervous system disease. In M3 patients, overall survival (OS) was 69.2% and 3-year event-free survival was 67.7%; in non-M3 patients, these rates were 45.3% and 36.7%, respectively. In non-M3 patients, OS was significantly different between transplanted (61.8%) and non-transplanted (38.2%) patients (p = 0.031). Conclusions: These results show a higher prevalence of the Franco-American-British M3 subtype than that reported in the international literature, as well as a decreased OS compared with that of developed countries. Further multicenter Brazilian studies with a larger sample size are encouraged to better understand the characteristics of acute myeloid leukemia, and to improve the treatment and prognosis in this population

Hematopoietic Stem Cell Transplantation in Primary Immunodeficiencies in Brazil-a Survey of the Working Group on Paediatric Transplantation of the Brazilian Society of Bone Marrow Transplantation

Inst Crianca HCFMUSP, Sao Paulo, BrazilHosp Israelita Albert Einstein, Sao Paulo, BrazilInst Oncol Pediat, Sao Paulo, BrazilHosp Clin Porto Alegre, Porto Alegre, RS, BrazilUniv Fed Parana, Bone Marrow Transplantat Unit, BR-80060000 Curitiba, Parana, BrazilCtr Oncol & Hematol, Jau, BrazilUSP Ribeirao Preto, Hosp Clin, Ribeirao Preto, BrazilUniv Fed Minas Gerais, Belo Horizonte, MG, BrazilUniv Fed Rio de Janeiro, Rio De Janeiro, BrazilCtr Nacl Transplate Medula Ossea CEMO, Inst Nacl Canc, Rio De Janeiro, BrazilUniv Fed Parana, Paediat Intens Care Unit, BR-80060000 Curitiba, Parana, BrazilNatl Inst Canc INCA, Rio De Janeiro, BrazilHosp Israelita Albert Einstein, Hematol & Bone Marrow Transplantat Dept, Sao Paulo, BrazilWeb of Scienc