412 research outputs found
Realistic following behaviors for crowd simulation
International audienceWhile walking through a crowd, a pedestrian experiences a large number of interactions with his neighbors. The nature of these interactions is varied, and it has been observed that macroscopic phenomena emerge from the combination of these local interactions. Crowd models have hitherto considered collision avoidance as the unique type of interactions between individuals, few have considered walking in groups. By contrast, our paper focuses on interactions due to the following behaviors of pedestrians. Following is frequently observed when people walk in corridors or when they queue. Typical macroscopic stop-and-go waves emerge under such traffic conditions. Our contributions are, first, an experimental study on following behaviors, second, a numerical model for simulating such interactions, and third, its calibration, evaluation and applications. Through an experimental approach, we elaborate and calibrate a model from microscopic analysis of real kinematics data collected during experiments. We carefully evaluate our model both at the microscopic and the macroscopic levels. We also demonstrate our approach on applications where following interactions are prominent
Ultrastructural changes of the intracellular surfactant pool in a rat model of lung transplantation-related events
<p>Abstract</p> <p>Background</p> <p>Ischemia/reperfusion (I/R) injury, involved in primary graft dysfunction following lung transplantation, leads to inactivation of intra-alveolar surfactant which facilitates injury of the blood-air barrier. The alveolar epithelial type II cells (AE2 cells) synthesize, store and secrete surfactant; thus, an intracellular surfactant pool stored in lamellar bodies (Lb) can be distinguished from the intra-alveolar surfactant pool. The aim of this study was to investigate ultrastructural alterations of the intracellular surfactant pool in a model, mimicking transplantation-related procedures including flush perfusion, cold ischemia and reperfusion combined with mechanical ventilation.</p> <p>Methods</p> <p>Using design-based stereology at the light and electron microscopic level, number, surface area and mean volume of AE2 cells as well as number, size and total volume of Lb were determined in a group subjected to transplantation-related procedures including both I/R injury and mechanical ventilation (I/R group) and a control group.</p> <p>Results</p> <p>After I/R injury, the mean number of Lb per AE2 cell was significantly reduced compared to the control group, accompanied by a significant increase in the luminal surface area per AE2 cell in the I/R group. This increase in the luminal surface area correlated with the decrease in surface area of Lb per AE2. The number-weighted mean volume of Lb in the I/R group showed a tendency to increase.</p> <p>Conclusion</p> <p>We suggest that in this animal model the reduction of the number of Lb per AE2 cell is most likely due to stimulated exocytosis of Lb into the alveolar space. The loss of Lb is partly compensated by an increased size of Lb thus maintaining total volume of Lb per AE2 cell and lung. This mechanism counteracts at least in part the inactivation of the intra-alveolar surfactant.</p
A Medium-Resolution Near-Infrared Spectral Library of Late Type Stars: I
We present an empirical infrared spectral library of medium resolution
(R~2000-3000) H (1.6 micron) and K (2.2 micron) band spectra of 218 red stars,
spanning a range of [Fe/H] from ~-2.2 to ~+0.3. The sample includes Galactic
disk stars, bulge stars from Baade's window, and red giants from Galactic
globular clusters. We report the values of 19 indices covering 12 spectral
features measured from the spectra in the library. Finally, we derive
calibrations to estimate the effective temperature, and diagnostic
relationships to determine the luminosity classes of individual stars from
near-infrared spectra.
This paper is part of a larger effort aimed at building a near-IR spectral
library to be incorporated in population synthesis models, as well as, at
testing synthetic stellar spectra.Comment: 34 pages, 12 figures; accepted for publication at ApJS; the spectra
are available from the authors upon reques
Shape optimization for the generalized Graetz problem
We apply shape optimization tools to the generalized Graetz problem which is a convection-diffusion equation. The problem boils down to the optimization of generalized eigen values on a two phases domain. Shape sensitivity analysis is performed with respect to the evolution of the interface between the fluid and solid phase. In particular physical settings, counterexamples where there is no optimal domains are exhibited. Numerical examples of optimal domains with different physical parameters and constraints are presented. Two different numerical methods (level-set and mesh-morphing) are show-cased and compared
Synthetic High-Resolution Line Spectra of Star-Forming Galaxies Below 1200A
We have generated a set of far-ultraviolet stellar libraries using spectra of
OB and Wolf-Rayet stars in the Galaxy and the Large and Small Magellanic Cloud.
The spectra were collected with the Far Ultraviolet Spectroscopic Explorer and
cover a wavelength range from 1003.1 to 1182.7A at a resolution of 0.127A. The
libraries extend from the earliest O- to late-O and early-B stars for the
Magellanic Cloud and Galactic libraries, respectively. Attention is paid to the
complex blending of stellar and interstellar lines, which can be significant,
especially in models using Galactic stars. The most severe contamination is due
to molecular hydrogen. Using a simple model for the H line strength, we
were able to remove the molecular hydrogen lines in a subset of Magellanic
Cloud stars. Variations of the photospheric and wind features of CIII 1176, OVI
1032, 1038, PV 1118, 1128, and SIV 1063, 1073, 1074 are discussed as a function
of temperature and luminosity class. The spectral libraries were implemented
into the LavalSB and Starburst99 packages and used to compute a standard set of
synthetic spectra of star-forming galaxies. Representative spectra are
presented for various initial mass functions and star formation histories. The
valid parameter space is confined to the youngest ages of less than 10 Myr for
an instantaneous burst, prior to the age when incompleteness of spectral types
in the libraries sets in. For a continuous burst at solar metallicity, the
parameter space is not limited. The suite of models is useful for interpreting
the restframe far-ultraviolet in local and high-redshift galaxies.Comment: 33 pages including 13 figures, accepted for publication in Ap
The OSACA Database and a Kinematic Analysis of Stars in the Solar Neighborhood
We transformed radial velocities compiled from more than 1400 published
sources, including the Geneva--Copenhagen survey of the solar neighborhood
(CORAVEL-CfA), into a uniform system based on the radial velocities of 854
standard stars in our list. This enabled us to calculate the average weighted
radial velocities for more than 25~000 HIPPARCOS stars located in the local
Galactic spiral arm (Orion arm) with a median error of +-1 km/s. We use these
radial velocities together with the stars' coordinates, parallaxes, and proper
motions to determine their Galactic coordinates and space velocities. These
quantities, along with other parameters of the stars, are available from the
continuously updated Orion Spiral Arm CAtalogue (OSACA) and the associated
database. We perform a kinematic analysis of the stars by applying an
Ogorodnikov-Milne model to the OSACA data. The kinematics of the nearest single
and multiple main-sequence stars differ substantially. We used distant
(r\approx 0.2 kpc) stars of mixed spectral composition to estimate the angular
velocity of the Galactic rotation -25.7+-1.2 km/s/kpc, and the vertex
deviation,l=13+-2 degrees, and detect a negative K effect. This negative K
effect is most conspicuous in the motion of A0-A5 giants, and is equal to
K=-13.1+-2.0 km/s/kpc.Comment: 16 pages, 8 figure
GYES, a multifibre spectrograph for the CFHT
We have chosen the name of GYES, one of the mythological giants with one
hundred arms, offspring of Gaia and Uranus, for our instrument study of a
multifibre spectrograph for the prime focus of the Canada-France-Hawaii
Telescope. Such an instrument could provide an excellent ground-based
complement for the Gaia mission and a northern complement to the HERMES project
on the AAT. The CFHT is well known for providing a stable prime focus
environment, with a large field of view, which has hosted several imaging
instruments, but has never hosted a multifibre spectrograph. Building upon the
experience gained at GEPI with FLAMES-Giraffe and X-Shooter, we are
investigating the feasibility of a high multiplex spectrograph (about 500
fibres) over a field of view 1 degree in diameter. We are investigating an
instrument with resolution in the range 15000 to 30000, which should provide
accurate chemical abundances for stars down to 16th magnitude and radial
velocities, accurate to 1 km/s for fainter stars. The study is led by
GEPI-Observatoire de Paris with a contribution from Oxford for the study of the
positioner. The financing for the study comes from INSU CSAA and Observatoire
de Paris. The conceptual study will be delivered to CFHT for review by October
1st 2010.Comment: Contributed talk at the Gaia ELSA conference 2010, S\`evres 7-11 June
2010, to be published on the EAS Series, Editors: C. Turon, F. Arenou & F.
Meynadie
Extracellular Hsp72 concentration relates to a minimum endogenous criteria during acute exercise-heat exposure
Extracellular heat-shock protein 72 (eHsp72) concentration increases during exercise-heat stress when conditions elicit physiological strain. Differences in severity of environmental and exercise stimuli have elicited varied response to stress. The present study aimed to quantify the extent of increased eHsp72 with increased exogenous heat stress, and determine related endogenous markers of strain in an exercise-heat model. Ten males cycled for 90 min at 50% O2peak in three conditions (TEMP, 20°C/63% RH; HOT, 30.2°C/51%RH; VHOT, 40.0°C/37%RH). Plasma was analysed for eHsp72 pre, immediately post and 24-h post each trial utilising a commercially available ELISA. Increased eHsp72 concentration was observed post VHOT trial (+172.4%) (P<0.05), but not TEMP (-1.9%) or HOT (+25.7%) conditions. eHsp72 returned to baseline values within 24hrs in all conditions. Changes were observed in rectal temperature (Trec), rate of Trec increase, area under the curve for Trec of 38.5°C and 39.0°C, duration Trec ≥ 38.5°C and ≥ 39.0°C, and change in muscle temperature, between VHOT, and TEMP and HOT, but not between TEMP and HOT. Each condition also elicited significantly increasing physiological strain, described by sweat rate, heart rate, physiological strain index, rating of perceived exertion and thermal sensation. Stepwise multiple regression reported rate of Trec increase and change in Trec to be predictors of increased eHsp72 concentration. Data suggests eHsp72 concentration increases once systemic temperature and sympathetic activity exceeds a minimum endogenous criteria elicited during VHOT conditions and is likely to be modulated by large, rapid changes in core temperature
On the nature of the Be star HR 7409 (7 Vul)
HR 7409 (7 Vul) is a newly identified Be star possibly part of the Gould Belt
and is the massive component of a 69-day spectroscopic binary. The binary
parameters and properties of the Be star measured using high-dispersion spectra
obtained at Ondrejov Observatory and at Rozhen Observatory imply the presence
of a low mass companion (~ 0.5-0.8 M_sun). If the pair is relatively young
(<50-80 Myr), then the companion is a K V star, but, following another, older
evolutionary scenario, the companion is a horizontal-branch star or possibly a
white dwarf star. In the latter scenario, a past episode of mass transfer from
an evolved star onto a less massive dwarf star would be responsible for the
peculiar nature of the present-day, fast-rotating Be star.Comment: Accepted for publication in MNRA
A catalog of visual double and multiple stars with eclipsing components
A new catalog of visual double systems containing eclipsing binaries as one
component is presented. The main purpose of this catalog is to compile a
complete list of all known multiples of this variety, both for current analysis
and to highlight those in need of additional observations. All available
photometric and astrometric data were analyzed, resulting in new orbits for
eight systems and new times of minimum light for a number of the eclipsing
binaries. Some of the systems in the catalog have acceptable solutions for
their visual orbits, although in most cases their orbital periods are too long
for simultaneous analysis. Also included, however, are a number of systems
which currently lack an orbital solution but which may be suitable for
simultaneous analysis in the future.Comment: 15 pages, 8 figures, 4 tables, published in A
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