36 research outputs found

    The influence of stereotypes about old age on the perception of elderly employees’ labor activity

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    In this article the problem of increasing retirement age in terms of age discrimination and creating conditions encouraging elderly people to continue to work is discussed. This paper presents a study of stereotypes that affect students of management specialties in Russian institutions of higher education between the ages of 20 to 25 years old. The stereotype is investigated in the context of emotionally colored image of reality simplifying the process of perceiving it. The correlation between the students’ existing stereotypes about elderly people and their perception of older employees has been conducted. As a result, 5 stereotypes that exist in young people have been defined. An analysis of the words chosen by students to describe the elderly shows little diversity in young people’s perception of them. Lexical analysis shows that in the Russian language there are practically no concepts which allow creating a positive image of the elderly. The influence of the stereotypes on the perception of elderly people in terms of employment shows that older specialists are perceived as people with experience and knowledge but these experience and knowledge are irrelevant to the present

    Publisher Correction: Biodiversity, environmental drivers, and sustainability of the global deep-sea sponge microbiome

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    The original version of the Description of Additional Supplementary Files associated with this Article contained errors in the legends of Supplementary Data 5–8 and omitted legends for the Source Data. The HTML has been updated to include a corrected version of the Description of Additional Supplementary Files; the original incorrect version of this file can be found as Supplementary Information associated with this Correction

    Biodiversity, environmental drivers, and sustainability of the global deep-sea sponge microbiome

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    In the deep ocean symbioses between microbes and invertebrates are emerging as key drivers of ecosystem health and services. We present a large-scale analysis of microbial diversity in deep-sea sponges (Porifera) from scales of sponge individuals to ocean basins, covering 52 locations, 1077 host individuals translating into 169 sponge species (including understudied glass sponges), and 469 reference samples, collected anew during 21 ship-based expeditions. We demonstrate the impacts of the sponge microbial abundance status, geographic distance, sponge phylogeny, and the physical-biogeochemical environment as drivers of microbiome composition, in descending order of relevance. Our study further discloses that fundamental concepts of sponge microbiology apply robustly to sponges from the deep-sea across distances of >10,000 km. Deep-sea sponge microbiomes are less complex, yet more heterogeneous, than their shallow-water counterparts. Our analysis underscores the uniqueness of each deep-sea sponge ground based on which we provide critical knowledge for conservation of these vulnerable ecosystems

    Relationships between the structure of insulin and its physiological effects - Thyronine insulin analogues

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    Elucidation of the structure of insulin has provided opportunities to explain its physiological properties. Following secretion directly into the hepatic portal vein, which flows directly to the liver, it acts initially to modulate hepatic glucose output, an effect primarily responsible for glucose homeostasis. Only 50% of secreted insulin passes from the liver to the other tissues where it has a role in controlling lipolysis and glucose uptake particularly after meals. In evolutionary terms selection pressure may have acted to optimize the affinity of the insulin to insulin receptor interaction in order to define the most appropriate relative hepatic to peripheral ratio of insulin action. Therapeutically insulin is given subcutaneously. This unphysiological route results in relative under-exposure of the liver to insulin with peripheral hyperinsulinaemia. By exploiting the peripheral capillary endothelium as a molecular sieve it is proving possible to design insulin analogues which compensate for this imbalance

    Structural organization of the human insulin receptor ectodomain

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