21 research outputs found

    Energy dependence of ϕ meson production at forward rapidity in pp collisions at the LHC

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    The production of ϕ\phi mesons has been studied in pp collisions at LHC energies with the ALICE detector via the dimuon decay channel in the rapidity region 2.5<y<42.5< y < 4. Measurements of the differential cross section d2σ/dydpT\mathrm{d}^2\sigma /\mathrm{d}y \mathrm{d}p_{\mathrm {T}} are presented as a function of the transverse momentum (pTp_{\mathrm {T}}) at the center-of-mass energies s=5.02\sqrt{s}=5.02, 8 and 13 TeV and compared with the ALICE results at midrapidity. The differential cross sections at s=5.02\sqrt{s}=5.02 and 13 TeV are also studied in several rapidity intervals as a function of pTp_{\mathrm {T}}, and as a function of rapidity in three pTp_{\mathrm {T}} intervals. A hardening of the pTp_{\mathrm {T}}-differential cross section with the collision energy is observed, while, for a given energy, pTp_{\mathrm {T}} spectra soften with increasing rapidity and, conversely, rapidity distributions get slightly narrower at increasing pTp_{\mathrm {T}}. The new results, complementing the published measurements at s=2.76\sqrt{s}=2.76 and 7 TeV, allow one to establish the energy dependence of ϕ\phi meson production and to compare the measured cross sections with phenomenological models. None of the considered models manages to describe the evolution of the cross section with pTp_{\mathrm {T}} and rapidity at all the energies.publishedVersio

    ϒ production in p–Pb collisions at sNN=8.16 TeV

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    ϒproduction in p–Pbinteractions is studied at the centre-of-mass energy per nucleon–nucleon collision √sNN=8.16TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03 &lt;3.53and −4.46 &lt;−2.96, down to zero transverse momentum. In this work, results on the ϒ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the ϒ(1S) yields with respect to ppcollisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the ϒ(2S) nuclear modification factor is evaluated, suggesting a suppression similar to that of the ϒ(1S). A first measurement of the ϒ(3S) has also been performed. Finally, results are compared with previous ALICE measurements in p–Pbcollisions at √sNN=5.02TeV and with theoretical calculations

    Prompt and nonprompt ψ (2S) production in pPb collisions at √sNN = 8. 16 TeV

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    The production of ψ(2S) mesons in proton-lead collisions at a centre-of-mass energy per nucleon pair of √sNN = 8.16 TeV is studied with the LHCb detector using data corresponding to an integrated luminosity of 34 nb−1. The prompt and nonprompt ψ(2S) production cross-sections and the ratio of the ψ(2S) to J/ψ cross-section are measured as a function of the meson transverse momentum and rapidity in the nucleon-nucleon centre-of-mass frame, together with forward-to-backward ratios and nuclear modification factors. The production of prompt ψ(2S) is observed to be more suppressed compared to pp collisions than the prompt J/ψ production, while the nonprompt productions have similar suppression factors

    Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

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    We have synthesized a family of rhein–huprine hybrids to hit several key targets for Alzheimer’s disease. Biological screening performed in vitro and in Escherichia coli cells has shown that these hybrids exhibit potent inhibitory activities against human acetylcholinesterase, butyrylcholinesterase, and BACE-1, dual Aβ42 and tau antiaggregating activity, and brain permeability. Ex vivo studies with the leads (+)- and (−)-<b>7e</b> in brain slices of C57bl6 mice have revealed that they efficiently protect against the Aβ-induced synaptic dysfunction, preventing the loss of synaptic proteins and/or have a positive effect on the induction of long-term potentiation. In vivo studies in APP-PS1 transgenic mice treated ip for 4 weeks with (+)- and (−)-<b>7e</b> have shown a central soluble Aβ lowering effect, accompanied by an increase in the levels of mature amyloid precursor protein (APP). Thus, (+)- and (−)-<b>7e</b> emerge as very promising disease-modifying anti-Alzheimer drug candidates

    Probing the chiral magnetic wave with charge-dependent flow measurements in Pb-Pb collisions at the LHC

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    The Chiral MagneticWave (CMW) phenomenon is essential to provide insights into the strong interaction in QCD, the properties of the quark-gluon plasma, and the topological characteristics of the early universe, offering a deeper understanding of fundamental physics in high-energy collisions. Measurements of the charge-dependent anisotropic flow coefficients are studied in Pb-Pb collisions at center-of-mass energy per nucleon-nucleon collision v sNN = 5.02TeV to probe the CMW. In particular, the slope of the normalized difference in elliptic (v2) and triangular (v3) flow coefficients of positively and negatively charged particles as a function of their event-wise normalized number difference, is reported for inclusive and identified particles. The slope rNorm 3 is found to be larger than zero and to have a magnitude similar to rNorm 2, thus pointing to a large background contribution for these measurements. Furthermore, rNorm 2 can be described by a blast wave model calculation that incorporates local charge conservation. In addition, using the event shape engineering technique yields a fraction of CMW (fCMW) contribution to this measurement which is compatible with zero. This measurement provides the very first upper limit for fCMW, and in the 10-60% centrality interval it is found to be 26% (38%) at 95% (99.7%) confidence level

    <math><mrow><msup><mi>K</mi><mo>*</mo></msup><msup><mrow><mo>(</mo><mn>892</mn><mo>)</mo></mrow><mn>0</mn></msup></mrow></math> and <math><mrow><mi>ϕ</mi><mo>(</mo><mn>1020</mn><mo>)</mo></mrow></math> production in <math><mi>p</mi><mtext>-</mtext><mi>Pb</mi></math> collisions at <math><mrow><msqrt><msub><mi>s</mi><mrow><mi>N</mi><mi>N</mi></mrow></msub></msqrt><mo>=</mo><mn>8.16</mn><mo> </mo><mi>TeV</mi></mrow></math>

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    International audienceThe production of K*(892)0and ϕ(1020)resonances has been measured in p-Pb collisions at sNN = 8.16 TeV using the ALICE detector. Resonances are reconstructed via their hadronic decay channels in the rapidity interval −0.5 &lt; y &lt; 0 and the transverse momentum spectra are measured for various multiplicity classes up to pT = 20 GeV/c for K*(892)0and pT = 16 GeV/c for ϕ(1020). The pT-integrated yields and mean transverse momenta are reported and compared with previous results in pp, p-Pb and Pb-Pb collisions. The xT scaling for K*(892)0and ϕ(1020)resonance production is newly tested in p-Pb collisions and found to hold in the high-pT region at Large Hadron Collider energies. The nuclear modification factors (RpPb) as a function of pT for K*0 and ϕ at sNN = 8.16 TeV are presented along with the new RpPb measurements of K*0, ϕ, Ξ, and Ω at sNN = 5.02 TeV. At intermediate pT (2–8 GeV/c), RpPb of Ξ, Ω show a Cronin-like enhancement, while K*0 and ϕ show no or little nuclear modification. At high pT (&gt;8 GeV/c), the RpPb values of all hadrons are consistent with unity within uncertainties. The RpPb of K*(892)0and ϕ(1020)at sNN = 8.16 and 5.02 TeV show no significant energy dependence

    Accessing the strong interaction between Λ baryons and charged kaons with the femtoscopy technique at the LHC

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    The interaction between Lambda baryons and kaons/antikaons is a crucial ingredient for the strangeness S= 0 and S= -2 sector of the meson-baryon interaction at low energies. In particular, the Lambda(K) over bar might help in understanding the origin of states such as the Xi(1620), whose nature and properties are still under debate. Experimental data on Lambda-K and Lambda-(K) over bar systems are scarce, leading to large uncertainties and tension between the available theoretical predictions constrained by such data. In this Letter we present the measurements of Lambda-K+ circle plus (Lambda) over bar -K- and Lambda-K- circle plus (Lambda) over bar -K+ correlations obtained in the high-multiplicity triggered data sample in pp collisions at root s= 13TeV recorded by ALICE at the LHC. The correlation function for both pairs is modeled using the Lednicky-Lyuboshits analytical formula and the corresponding scattering parameters are extracted. The Lambda-K- circle plus (Lambda) over bar -K+ correlations show the presence of several structures at relative momenta k* above 200 MeV/c, compatible with the Omega baryon, the Xi(1690), and Xi(1820) resonances decaying into Lambda-K- pairs. The low k* region in the Lambda-K- circle plus (Lambda) over bar -K+ also exhibits the presence of the Xi(1620) state, expected to strongly couple to the measured pair. The presented data allow to access the Lambda K+ and Lambda K- strong interaction with an unprecedented precision and deliver the first experimental observation of the Xi(1620) decaying into Lambda K-. (c) 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP3

    Λ+c production in pp and in p-Pb collisions at √sNN=5.02 TeV

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    The production cross section of prompt Λ+c charm baryons was measured with the ALICE detector at the LHC at midrapidity in proton-proton (pp) and proton-lead (p–Pb) collisions at a center-of-mass energy per nucleon pair of √sNN=5.02 TeV. The Λ+c and Λ¯−c baryons were reconstructed in the hadronic decay channels Λ+c→pK−π+ and Λ+c→pK0S and respective charge conjugates. The measured differential cross sections as a function of transverse momentum (pT) and the pT-integrated Λ+c production cross section in pp and in p–Pb collisions are presented. The Λ+c nuclear modification factor (RpPb), calculated from the cross sections in pp and in p–Pb collisions, is presented and compared with the RpPb of D mesons. The Λ+c/D0 ratio is also presented and compared with the light-flavor baryon-to-meson ratios p/π and Λ/K0S, and measurements from other LHC experiments. The results are compared to predictions from model calculations and Monte Carlo event generators
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