The SVOM gamma-ray burst mission

We briefly present the science capabilities, the instruments, the operations, and the expected performance of the SVOM mission. SVOM (Space-based multiband astronomical Variable Objects Monitor) is a Chinese-French space mission dedicated to the study of Gamma-Ray Bursts (GRBs) in the next decade. The SVOM mission encompasses a satellite carrying four instruments to detect and localize the prompt GRB emission and measure the evolution of the afterglow in the visible band and in X-rays, a VHF communication system enabling the fast transmission of SVOM alerts to the ground, and a ground segment including a wide angle camera and two follow-up telescopes. The pointing strategy of the satellite has been optimized to favor the detection of GRBs located in the night hemisphere. This strategy enables the study of the optical emission in the first minutes after the GRB with robotic observatories and the early spectroscopy of the optical afterglow with large telescopes to measure the redshifts. The study of GRBs in the next decade will benefit from a number of large facilities in all wavelengths that will contribute to increase the scientific return of the mission. Finally, SVOM will operate in the era of the next generation of gravitational wave detectors, greatly contributing to searches for the electromagnetic counterparts of gravitational wave triggers at Xray and gamma-ray energies.Comment: 13 pages, 5 figures, published by PoS, proceedings of the conference Swift: 10 Years of Discovery, 2-5 December 2014, La Sapienza University, Rome, Ital

The role of calcium ions in toxic cell injury.

Calcium ions have been increasingly implicated as a mediator of the mechanisms generating lethal cell injury under a variety of pathologic circumstances. An overview of the various roles suggested for such alterations in cellular calcium homeostasis is presented. The central role of plasma membrane damage in the genesis of irreversible cell injury is used to divide the postulated roles for calcium ions into two major mechanisms. On the one hand, calcium ions have been proposed as mediators of the functional consequences of plasma membrane injury. An influx of extracellular calcium ions across a damaged permeability barrier and down a steep concentration gradient may convert potentially reversible injury into irreversible injury. On the other hand, alterations in intracellular calcium homeostasis are postulated to participate in the mechanisms generating potentially lethal plasma membrane injury. The release of calcium stores sequestered within intracellular organelles raises the cytosolic concentration of free calcium, a process that may activate, in turn, a number of membrane-disruptive processes. The data supporting these two distinct actions of calcium are reviewed and discussed

The enhanced X-ray Timing and Polarimetry mission – eXTP: an update on its scientific cases, mission profile and development status

The enhanced X-ray Timing and Polarimetry mission (eXTP) is a flagship observatory for X-ray timing, spectroscopy and polarimetry developed by an International Consortium. Thanks to its very large collecting area, good spectral resolution and unprecedented polarimetry capabilities, eXTP will explore the properties of matter and the propagation of light in the most extreme conditions found in the Universe. eXTP will, in addition, be a powerful X-ray observatory. The mission will continuously monitor the X-ray sky, and will enable multiwavelength and multi-messenger studies. The mission is currently in phase B, which will be completed in the middle of 2022

The LOFT mission concept: a status update

The Large Observatory For x-ray Timing (LOFT) is a mission concept which was proposed to ESA as M3 and M4 candidate in the framework of the Cosmic Vision 2015-2025 program. Thanks to the unprecedented combination of effective area and spectral resolution of its main instrument and the uniquely large field of view of its wide field monitor, LOFT will be able to study the behaviour of matter in extreme conditions such as the strong gravitational field in the innermost regions close to black holes and neutron stars and the supra-nuclear densities in the interiors of neutron stars. The science payload is based on a Large Area Detector (LAD, >8m2 effective area, 2-30 keV, 240 eV spectral resolution, 1 degree collimated field of view) and a Wide Field Monitor (WFM, 2-50 keV, 4 steradian field of view, 1 arcmin source location accuracy, 300 eV spectral resolution). The WFM is equipped with an on-board system for bright events (e.g., GRB) localization. The trigger time and position of these events are broadcast to the ground within 30 s from discovery. In this paper we present the current technical and programmatic status of the mission

The wide field monitor onboard the eXTP mission

The eXTP (enhanced X-ray Timing and Polarimetry) mission is a major project of the Chinese Academy of Sciences (CAS) and China National Space Administration (CNSA) currently performing an extended phase A study and proposed for a launch by 2025 in a low-earth orbit. The eXTP scientific payload envisages a suite of instruments (Spectroscopy Focusing Array, Polarimetry Focusing Array, Large Area Detector and Wide Field Monitor) offering unprecedented simultaneous wide-band X-ray timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study and it is expected to provide key hardware elements, including a Wide Field Monitor (WFM). The WFM instrument for eXTP is based on the design originally proposed for the LOFT mission within the ESA context. The eXTP/WFM envisages a wide field X-ray monitor system in the 2-50 keV energy range, achieved through the technology of the large-area Silicon Drift Detectors. The WFM will consist of 3 pairs of coded mask cameras with a total combined Field of View (FoV) of 90×180 degrees at zero response and a source localization accuracy of ~1 arcmin. In this paper we provide an overview of the WFM instrument design, including new elements with respect to the earlier LOFT configuration, and anticipated performance