125 research outputs found
Diffractive Photon Production in Gamma-P and Gamma-Gamma Interactions
We study the diffractive production of photons in gamma-p and gamma-gamma
collisions. We specifically compute the rates for gamma*-p -> gamma-X and for
gamma*-gamma* -> gamma-gamma, where X denotes the proton dissociation. We focus
on the rates at large momentum transfers, -t >> Lambda^2, where we are most
confident in the use of QCD perturbation theory. However, our calculations do
allow us to study the -t -> 0 behaviour of the gamma*-gamma*-> gamma-gamma
process in the region where the incoming photons are sufficiently virtual.Comment: 17 pages, 4 figure
Diffractive production of high pt photons at HERA
We study the diffractive production of high pt photons at HERA. We have
implemented the process as a new hard sub-process in the HERWIG event generator
in order to prepare the ground for a future measurement.Comment: 4 pages, 4 figures. Contribution to the 1999 UK Phenomenology
Workshop on Collider Physics, Durham, U
Tagging Two-Photon Production at the LHC
Tagging two-photon production offers a significant extension of the LHC
physics programme. Effective luminosity of high-energy gamma-gamma collisions
reaches 1% of the proton-proton luminosity and the standard detector techniques
used for measuring very forward proton scattering should allow for a reliable
extraction of interesting two-photon interactions. Particularly exciting is a
possibility of detecting two-photon exclusive Higgs boson production at the
LHC.Comment: 9 pages and 4 figure
Recommended from our members
Membrane-initiated nuclear trafficking of the glucocorticoid receptor in hypothalamic neurons
Glucocorticoid binding to the intracellular glucocorticoid receptor (GR) stimulates the translocation of the GR from the cytosol to the nucleus, which leads to the transactivation or transrepression of gene transcription. However, multiple lines of evidence suggest that glucocorticoid signaling can also be initiated from the plasma membrane. Here, we provide evidence for membrane-initiated glucocorticoid signaling by a membrane-impermeant dexamethasone-bovine serum albumin (Dex-BSA) conjugate, which induced GR nuclear trafficking in hypothalamic neurons in vitro and in vivo. The GR nuclear translocation induced by a membrane-impermeant glucocorticoid suggests trafficking of an unliganded GR. The membrane-initiated GR trafficking was not blocked by inhibiting ERK MAPK, p38 MAPK, PKA, Akt, Src kinase, or calcium signaling, but was inhibited by Akt activation. Short-term exposure of hypothalamic neurons to dexamethasone (Dex) activated the glucocorticoid response element (GRE), suggesting transcriptional transactivation, whereas exposure to the Dex-BSA conjugate failed to activate the GRE, suggesting differential transcriptional activity of the liganded compared to the unliganded GR. Microarray analysis revealed divergent transcriptional regulation by Dex-BSA compared to Dex. Together, our data suggest that signaling from a putative membrane glucocorticoid receptor induces the trafficking of unliganded GR to the nucleus, which elicits a pattern of gene transcription that differs from that of the liganded receptor. The differential transcriptional signaling by liganded and unliganded receptors may contribute to the broad range of genetic regulation by glucocorticoids, and may help explain some of the different off-target actions of glucocorticoid drugs
Testing the dynamics of high energy scattering using vector meson production
I review work on diffractive vector meson production in photon-proton
collisions at high energy and large momentum transfer, accompanied by proton
dissociation and a large rapidity gap. This process provides a test of the high
energy scattering dynamics, but is also sensitive to the details of the
treatment of the vector meson vertex.
The emphasis is on the description of the process by a solution of the
non-forward BFKL equation, i.e. the equation describing the evolution of
scattering amplitudes in the high-energy limit of QCD. The formation of the
vector meson and the non-perturbative modeling needed is also briefly
discussed.Comment: 17 pages, 8 figures. Brief review to appear in Mod. Phys. Lett.
The QCD description of diffractive processes
We review the application of perturbative QCD to diffractive processes. We
introduce the two gluon exchange model to describe diffractive qq(bar) and
qq(bar)g production in deep inelastic scattering. We study the triple Regge
limit and briefly consider multiple gluon exchange. We discuss diffractive
vector meson production at HERA both at t = 0 and large |t|. We demonstrate the
non-factorization of diffractive processes at hadron colliders.Comment: 39 pages, 14 figures, LaTeX, new references added and some discussion
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TESLA Technical Design Report Part III: Physics at an e+e- Linear Collider
The TESLA Technical Design Report Part III: Physics at an e+e- Linear
ColliderComment: 192 pages, 131 figures. Some figures have reduced quality. Full
quality figures can be obtained from http://tesla.desy.de/tdr. Editors -
R.-D. Heuer, D.J. Miller, F. Richard, P.M. Zerwa
FLAIR* to visualize veins in white matter lesions: A new tool for the diagnosis of multiple sclerosis?
Royal College of Radiologists (pump priming grant to RJPS).
MEM is partly funded (20%) by the Barts and the London National Institute for Health Research
Cardiovascular Biomedical Research Unit.
Additional study support provided by the Intramural Research Program of
the National Institute of Neurological Disorders and Stroke, USA
Adhesion and proliferation of living cell on surface functionalized with glycine nanostructures
This research presents the application of glycine amino acid for establishing firm cell-substrate interaction instead of expensive adhesion proteins, peptides and peptide derivatives. The glycine amino acid is chemically functionalized on the coverslip to achieve self-assembled nanostructure. Glycine self-assembly on NaCl treated coverslips is initiated with SiONa+:COO− linkage while their nanostructure is achieved with formation of glycine chain through NH3+:COO− covalent linkage between the adjacent molecules. The functionalization steps are confirmed by Fourier-transform infrared spectroscopy (FTIR) investigation. The atomic force microscopy (AFM) and scanning electron microscopy (SEM) investigations reveal that glycine growth initiates at 4 Hours (H) post-treatment while maximum growth appears after 8H-10H. Both the vertical and horizontal growth of nanostructures show dependence on functionalization periods. Various levels of glycine functionalized surface show different levels of baby hamster kidney (BHK-21) cell adhesion and proliferation efficiency with maximum performance for 10H functionalized surface. The adhesion and proliferation performance of 10H glycine functionalized surface shows negligible difference when compared with glycine-aspartic acid (RGD) functionalized surface. Finally, growth curves obtained from both glycine and RGD functionalized surface reveal exponential growth phage up to 48H followed by stationary phage between 48H and 72H while death of many cells appears from 72H to 96H. Thus, this research concluded that glycine functionalized surface is equally effective for cell adhesion and proliferation
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations
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