R-local Delaunay inhibition model

Let us consider the local specification system of Gibbs point process with inhib ition pairwise interaction acting on some Delaunay subgraph specifically not con taining the edges of Delaunay triangles with circumscribed circle of radius grea ter than some fixed positive real value $R$. Even if we think that there exists at least a stationary Gibbs state associated to such system, we do not know yet how to prove it mainly due to some uncontrolled "negative" contribution in the expression of the local energy needed to insert any number of points in some large enough empty region of the space. This is solved by introducing some subgraph, called the $R$-local Delaunay graph, which is a slight but tailored modification of the previous one. This kind of model does not inherit the local stability property but satisfies s ome new extension called $R$-local stability. This weakened property combined with the local property provides the existence o f Gibbs state.Comment: soumis \`{a} Journal of Statistical Physics 27 page

Prospects on the application of necessary optimality conditions on the resolution of the Goddard problem with unknown bounded parameters using interval arithmetics

International audienc

Prospects on solving an optimal control problem with bounded uncertainties on parameters using interval arithmetic

An interval method based on Pontryagin’s Minimum Principle is proposed to enclose the solutions of an optimal control problem with embedded bounded uncertainties. This method is used to compute an enclosure of all optimal trajectories of the problem, as well as open loop and closed loop enclosures meant to validate an optimal guidance algorithm on a concrete system with inaccurate knowledge of the parameters. The differences in geometry of these enclosures are exposed, and showcased on a simple system. These enclosures can guarantee that a given optimal control problem will yield a satisfactory trajectory for any realization of the uncertainties. Contrarily, the probability of failure may not be eliminated and the problem might need to be adjusted

Antialactone: A New γ-Lactone from Antiaris africana, and its Absolute Configuration Determined from TDDFT CD Calculations

Four compounds were isolated from the stem bark of Antiaris africana. One of them, a γ-lactone named antialactone (1a), is reported for the first time as a natural product. The structures were determined by comprehensive analyses of their 1D and 2D NMR spectra and EI MS data. The absolute configuration of antialactone acetate (1b) was established by TDDFT CD calculations and comparison with measured CD spectra. The remaining three known compounds were identified, by comparing their spectroscopic data with those reported in the literature, as lichenxanthone, β-sitosterol, and betulinic acid

Activation biophysique chez des patients schizophrènes sous différents traitements médicamenteux pris en charge au Service d’Addictologie et Hygiène Mentale d’Abidjan

La résilience biophysique des patients schizophrènes semble dépendre du traitement médicamenteux dont ils bénéficient. La prise en compte du traitement antipsychotique dans l’ajustement de l’activation biophysiologique chez ces derniers est loin d’être suffisamment explorée. La présente étude se propose d’examiner l’activation biophysique chez des schizophrènes en fonction du type de traitement médicamenteux auquel ils sont soumis. Elle porte sur 145 patients ayant un âge compris entre 16 à 35 ans avec 91 sujets dont 40 femmes et 51 hommes qui sont sous un traitement antipsychotique de première génération et 54 sujets dont 26 femmes et 28 hommes bénéficiant d’un traitement antipsychotique de deuxième génération. L’examen des résultats de l’activation biophysique s’est fait, en considérant le poids, l’IMC, le tour de taille et le tour de hanche. Ceux-ci ont été obtenus par l’utilisation d’une balance électronique (le poids) et d’un ruban mètre pour la mesure du tour de tailles et le tour de hanches. Les traitements antipsychotiques ont été évalués par l’examen des dossiers de consultation de chaque sujet malade. La normalité de la distribution des données a été testée statiquement en utilisant le test de Shapiro-Wilk (p-value= 0,964).  Les résultats au test de t student montrent que les schizophrènes mis sous un traitement antipsychotique de première génération présentent une activation biophysique qui diffère de celle de leurs homologues bénéficiant d’un traitement antipsychotique de deuxième génération (p-value= 0,000 < 0,05). Les schizophrènes sous un traitement antipsychotique de première génération présentent un profil biophysique supérieur à ceux de leurs pairs soumis à un traitement antipsychotique de seconde génération. Le type de traitement médicamenteux exerce un effet différent sur le fonctionnement biophysique des schizophrènes.   The biophysical resilience of schizophrenic patients seems to depend on the medication they receive. The role of antipsychotic treatment in the adjustment of biophysiological activation in schizophrenic patients is far from being sufficiently explored.  The present study examines biophysiological activation in schizophrenics as a function of the type of drug treatment they receive. It involved 145 patients aged between 16 and 35, with 91 subjects (40 women and 51 men) on first-generation antipsychotic treatment and 54 subjects (26 women and 28 men) on second-generation antipsychotic treatment. The results of biophysical activation were examined in terms of weight, BMI, waist circumference and hip circumference. These were obtained using an electronic scale (weight) and a tape measure for waist and hip circumferences. Antipsychotic treatments were assessed by examining the consultation records of each patient. The normality of the data distribution was statically tested using the Shapiro-Wilk test (p-value= 0.964).  The results of the t-student test show that schizophrenics on first-generation antipsychotic treatment have a biophysical activation that differs from that of their counterparts on second-generation antipsychotic treatment (p-value= 0.000 < 0.05). Schizophrenics undergoing first-generation antipsychotic treatment show a more superior biophysical profile than their peers undergoing second-generation antipsychotic treatment. The type of drug treatment has a different effect on the biophysical functioning of schizophrenics

3D-Voronoi Diagramme zur quantitativen Bildanalyse in der Interphase-Cytogenetik

Um die Anordnung von Chromosomen in Zellkernen der Interphase zu untersuchen, wurde ein Verfahren aus der Computergeometrie adaptiert. Dieser Ansatz basiert auf der Zerlegung von dreidimensionalen Bildvolumen mithilfe des Voronoi-Diagramms in konvexe Polyeder. Die graphenorientierte, geometrische Struktur dieses Verfahrens ermöglicht sowohl eine schnelle Extraktion von Objekten im Bildraum als auch die Berechnung morphologischer Parameter wie Volumina, Oberflächen und Rundheitsfaktoren. In diesem Beitrag wird exemplarisch die dreidimensionale Morphologie von XChromosomen in weiblichen Interphasezellkernen mithilfe dieser drei Parameter untersucht. Um diese Zellkerne mit lichtoptischen Methoden zu untersuchen, wurden die Territorien der X-Chromosomen mit einem molekularcytogenetischen Verfahren fluoreszierend dargestellt. Zur Unterscheidung des aktiven und inaktiven X-Chromosoms wurde das Barr-Körperchen zusätzlich markiert und mithilfe eines Epifluoreszenzmikroskops, ausgerüstet mit einer CCD-Kamera, aufgenommen. Anschließend wurden 1 2 - 2 5 äquidistante, lichtoptische Schnitte der X-Chromosomenterritorien mit einem konfokalen Laser Scanning Mikroskop (CLSM) aufgenommen. Diese lichtoptischen Schnitte wurden mithilfe des Voronoi-Verfahrens segmentiert und analysiert. Methoden aus der Computergraphik wurden zur Visualisierung der Ergebnisse eingesetzt. Es konnte gezeigt werden, daß mithilfe des Voronoi-Verfahrens Chromosomen- Territorien anhand der morphologischen Parameter zuverlässig beschrieben werden können

Taxys = Esterel + Kronos: A tool for verifying real-time properties of embedded systems

The goal of TAXYS is to provide a framework for developing real-time embedded code and verifying its correct behavior with respect to quantitative timing requirements. To achieve so, TAXYS connects France Telecom's ESTEREL compiler SAXO-RT with VERIMAG's model-checker KRONOS. TAXYS has been successfully applied on real industrial telecommunication systems, such as a GSM radio link from Alcatel and a phone prototype from France Telecom

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal