A methodological approach for assessing flexibility and capacity value in renewable-dominated power systems: A Spanish case study in 2030

Maintaining the security of supply is one of the challenges that system operators face. Variability and uncertainty increase due to the penetration of variable renewable energy sources such as solar and wind, while flexible technologies such as traditional thermal units are phased out to reduce emissions. The current methods for assessing power system adequacy are based on historical operations and are generally intended to be applied to thermal-dominated electricity systems. Therefore, it is necessary to improve current adequacy assessment methods since they usually neglect the flexibility of power systems. This paper presents a methodological approach for jointly assessing the adequacy and flexibility of power systems. The methodology's usefulness is demonstrated through its application to the Spanish power system. For the case study, results show that new closed-looped pumped storage hydro technology provides 25% flexibility while contributing to adequacy due to higher installed capacity and round-trip efficiency. Due to shorter storage duration, batteries only contribute to flexibility, supplying 16% of the total operating reserves. Therefore, this study shows that metrics of flexibility and individual contribution to the power system adequacy complement each other and simultaneously enable the scarcities of power systems to be observed.This research has been carried out thanks to the Spanish Ministry of Economy and Competitiveness MINECO through BC3 María de Maeztu excellence accreditation MDM-2017-0714 Maria de Maeztu Grant

AUTHENTIC ASSESSMENT FOR IMPROVING TEACHING QUALITY: PORTFOLIO AND SLC IN PAPUA HARAPAN SCHOOL

Background of this paper based on researchers concern against a challenge in the world of education ahead of the 21st century. Researchers realize that to enter the 21st century, teachers must improve the quality of their teaching in implementing the curriculum in class. Currently, Indonesia has implemented use curriculum 2013. The curriculum 2013 use scientific approach rendering accompanied by some new change in Indonesia curriculum system. One of the things the form of renewal is in applying assessment to the students. Assessment is one of the most important part in the success of students and teachers. Hence, this study aims to describe and review research in implementing the model of authentic assessment to improve the teachers teaching quality at Papua Harapan School through portfolio and SLC (Students Led Conference). Through this study, researchers want to review of what the models authentic assessment which has been implemented in Papua Harapan School. The authentic assessment through portfolio and SLC (Students Led Conference) that is not focus only on the final result but rather than, assessment based on the learning process that has been traversed by the students. Based on the review of research obtained that authentic assessment able to improve the teaching quality of teachers. Teachers can make the authentic assessment as a result of achievement reflection of the learning objective so as to the teaching quality of teachers could be improved through the result of authentic assessment

Science for loss and damage. Findings and propositions

The debate on “Loss and Damage” (L&D) has gained traction over the last few years. Supported by growing scientific evidence of anthropogenic climate change amplifying frequency, intensity and duration of climate-related hazards as well as observed increases in climate-related impacts and risks in many regions, the “Warsaw International Mechanism for Loss and Damage” was established in 2013 and further supported through the Paris Agreement in 2015. Despite advances, the debate currently is broad, diffuse and somewhat confusing, while concepts, methods and tools, as well as directions for policy remain vague and often contested. This book, a joint effort of the Loss and Damage Network—a partnership effort by scientists and practitioners from around the globe—provides evidence-based insight into the L&D discourse by highlighting state-of-the-art research conducted across multiple disciplines, by showcasing applications in practice and by providing insight into policy contexts and salient policy options. This introductory chapter summarises key findings of the twenty-two book chapters in terms of five propositions. These propositions, each building on relevant findings linked to forward-looking suggestions for research, policy and practice, reflect the architecture of the book, whose sections proceed from setting the stage to critical issues, followed by a section on methods and tools, to chapters that provide geographic perspectives, and finally to a section that identifies potential policy options. The propositions comprise (1) Risk management can be an effective entry point for aligning perspectives and debates, if framed comprehensively, coupled with climate justice considerations and linked to established risk management and adaptation practice; (2) Attribution science is advancing rapidly and fundamental to informing actions to minimise, avert, and address losses and damages; (3) Climate change research, in addition to identifying physical/hard limits to adaptation, needs to more systematically examine soft limits to adaptation, for which we find some evidence across several geographies globally; (4) Climate risk insurance mechanisms can serve the prevention and cure aspects emphasised in the L&D debate but solidarity and accountability aspects need further attention, for which we find tentative indication in applications around the world; (5) Policy deliberations may need to overcome the perception that L&D constitutes a win-lose negotiation “game” by developing a more inclusive narrative that highlights collective ambition for tackling risks, mutual benefits and the role of transformation

Coupling circularity performance and climate action: from disciplinary silos to transdisciplinary modelling science

Technological breakthroughs and policy measures targeting energy efficiency and clean energy alone will not suffice to deliver Paris Agreement-compliant greenhouse gas emissions trajectories in the next decades. Strong cases have recently been made for acknowledging the decarbonisation potential lying in transforming linear economic models into closed-loop industrial ecosystems and in shifting lifestyle patterns towards this direction. This perspective highlights the research capacity needed to inform on the role and potential of the circular economy for climate change mitigation and to enhance the scientific capabilities to quantitatively explore their synergies and trade-offs. This begins with establishing conceptual and methodological bridges amongst the relevant and currently fragmented research communities, thereby allowing an interdisciplinary integration and assessment of circularity, decarbonisation, and sustainable development. Following similar calls for science in support of climate action, a transdisciplinary scientific agenda is needed to co-create the goals and scientific processes underpinning the transition pathways towards a circular, net-zero economy with representatives from policy, industry, and civil society. Here, it is argued that such integration of disciplines, methods, and communities can then lead to new and/or structurally enhanced quantitative systems models that better represent critical industrial value chains, consumption patterns, and mitigation technologies. This will be a crucial advancement towards assessing the material implications of, and the contribution of enhanced circularity performance to, mitigation pathways that are compatible with the temperature goals of the Paris Agreement and the transition to a circular economy

Fasciola hepatica calcium-binding protein FhCaBP2: structure of the dynein light chain-like domain

The common liver fluke Fasciola hepatica causes an increasing burden on human and animal health, partly because of the spread of drug-resistant isolates. As a consequence, there is considerable interest in developing new drugs to combat liver fluke infections. A group of potential targets is a family of calcium-binding proteins which combine an N-terminal domain with two EF-hand motifs and a C-terminal domain with predicted similarity to dynein light chains (DLC-like domain)

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

Type-2 Familial Partial Lipodystrophy is caused by LMNA mutations. Patients gradually lose subcutaneous fat from the limbs, while they accumulate adipose tissue in the face and neck. Several studies have demonstrated that autophagy is involved in the regulation of adipocyte differentiation and the maintenance of the balance between white and brown adipose tissue. We identified deregulation of autophagy in laminopathic preadipocytes before induction of differentiation. Moreover, in differentiating white adipocyte precursors, we observed impairment of large lipid droplet formation, altered regulation of adipose tissue genes, and expression of the brown adipose tissue marker UCP1. Conversely, in lipodystrophic brown adipocyte precursors induced to differentiate, we noticed activation of autophagy, formation of enlarged lipid droplets typical of white adipocytes, and dysregulation of brown adipose tissue genes. In agreement with these in vitro results indicating conversion of FPLD2 brown preadipocytes toward the white lineage, adipose tissue from FPLD2 patient neck, an area of brown adipogenesis, showed a white phenotype reminiscent of its brown origin. Moreover, in vivo morpho-functional evaluation of fat depots in the neck area of three FPLD2 patients by PET/CT analysis with cold stimulation showed the absence of brown adipose tissue activity. These findings highlight a new pathogenetic mechanism leading to improper fat distribution in lamin A-linked lipodystrophies and show that both impaired white adipocyte turnover and failure of adipose tissue browning contribute to disease.We thank FPLD2 patients for donating biological samples. We thank the Italian Network for Laminopathies and the European Consortium of Lipodystrophies (ECLip) for support and helpful discussion. We thank Aurelio Valmori for the technical support. The studies were supported by Rizzoli Orthopedic Institute “5 per mille” 2014 project to MC, AIProSaB project 2016 and Fondazione Del Monte di Bologna e Ravenna grant 2015–2016 “New pharmacological approaches in bone laminopathies based on the use of antibodies neutralizing TGF beta 2” to GL. GL is also supported by PRIN MIUR project 2015FBNB5Y.S

LOW CLIMATE STABILISATION UNDER DIVERSE GROWTH AND CONVERGENCE SCENARIOS

International audienceFew papers have analysed the consequences of low climate stabilisation. Most models and scenarios assume that future trends in global GDP will be similar to the growth experienced in the past century, which would imply multiplying current output nineteen-fold in this century. However, natural resource and environmental constraints suggest that future global economic growth may not be so high. Furthermore, the environmental implications of such growth depend on how it is distributed across countries. This paper studies the implications on GHG abatement policies of different assumptions on global GDP growth and convergence levels. A partial equilibrium model (POLES) of the world's energy system is used to provide detailed projections up to 2050 for the different regions of the world. The results suggest that while low stabilisation is technically feasible and economically viable for the world in all the scenarios considered, it is more likely to occur with more modest global growth. Convergence in living standards on the other hand places greater pressures in terms of the required reduction in emissions. In general we find that there are major differences between regions in terms of the size and the timing of abatement costs and economic impact