14 research outputs found
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field
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Laurence F. Gross. The Course of Industrial Decline: The Boott Cotton Mills of Lowell, Massachusetts, 1835â1955. Baltimore and London: The Johns Hopkins University Press, 1993. xvii + 279. $42.00 cloth.
William Gibbs McAdoo: A Passion for Change 1863â1917. By John J. Broesamle. Port Washington, N.Y., Kennikat Press, 1974. Pp. xii + 304. $15.00.
Book Reviews
Gerald G. Eggert reviews Forging America: Ironworkers, Adventurers, and the Industrious Revolution by John BezĂs-Selfa.David M. Stameshkin reviews The Making of Princeton University: From Woodrow Wilson to the Present by James AxtellHerbert Ershkowitz reviews Mysteries of My Father by Thomas Flemin