26 research outputs found
Methods of probing the interactions between small molecules and disordered proteins
- Author
- A Bhowmick
- A Favier
- A Kiessling
- A Kiessling
- A Mashaghi
- A Solanki
- A Toto
- AB Singleton
- AC Bloomer
- ACM Ferreon
- ACM Ferreon
- AK Dunker
- AK Dunker
- AV Follis
- AV Follis
- B Brutscher
- B Bulic
- B Schuler
- BL Schwartz
- BR Brooks
- C Abrams
- C Camilloni
- C Camilloni
- C Camilloni
- C Dalvit
- C Galvagnion
- C Haass
- C Harrington
- C Lendel
- C Uetrecht
- CC Lee
- CM Dobson
- CR Connors
- D Chabas
- D Grote
- D Ringe
- D Schneidman-Duhovny
- DG Myszka
- DI Hammoudeh
- E Gazit
- E Hellstrand
- EA Mirecka
- F Jin
- F Palazzesi
- F-X Theillet
- FA Aprile
- FE Herrera
- Francesco A. Aprile
- FT Hane
- G Hummer
- G Larsson
- G Li
- G Meisl
- G Mustata
- G Platzer
- G Tóth
- G Xanthou
- Gabriella T. Heller
- GT Heller
- GT Heller
- GT Heller
- H Wang
- HJ Dyson
- HJ Dyson
- HJ Sass
- HV Erkizan
- I Bertini
- I Caesar
- I Liko
- IC Felli
- IC Felli
- J Concepcion
- J Dogan
- J Habchi
- J Habchi
- J Habchi
- J Hardy
- J Henriques
- J Li
- J Michel
- J Nováček
- J Sevigny
- J Shi
- J Wang
- JA McLaurin
- JF Ge
- JJ Ward
- JJ Zarranz
- JL Neira
- JM Perchiacca
- JR Forman
- K Kazimierczuk
- K Lindorff-Larsen
- K Tamiola
- K Uaesoontrachoon
- K Wüthrich
- K-C Jeong
- KA Conway
- KC Neuman
- KS Molnar
- KX Wang
- L Konermann
- L Xu
- L Young
- LI Iconaru
- LM Iakoucheva
- LM Young
- LT Vassilev
- M Bonomi
- M Bonomi
- M Bonomi
- M Convertino
- M Fuxreiter
- M Fuxreiter
- M Groenning
- M Mayer
- M Mobli
- M Necula
- M Perni
- M Pickhardt
- M Rückert
- M Sandal
- M Vidal
- M Zhu
- M-C Lo
- MA Freitas
- Marsh Ja
- MC Chartier-Harlin
- MD Carter
- MG Fried
- MH Polymeropoulos
- Michele Vendruscolo
- MM Babu
- MR Cookson
- MR Hansen
- MS Nasir
- N Cremades
- N Gassler
- N Krishnan
- N Tjandra
- NH Pawley
- NJ Greenfield
- NP Cowieson
- P Arosio
- P Arosio
- P Bernadó
- P Bernadó
- P Ibáñez
- P Joshi
- P Schanda
- P Sormanni
- P Sormanni
- P Tompa
- P Tompa
- P Tompa
- P Tompa
- PE Wright
- Q-L Ma
- R Beveridge
- R Cuchillo
- R Hovius
- R Konrat
- R Krüger
- R Lebel
- R Tycko
- S Gil
- S Rauscher
- S Sanglier
- S Shangary
- S Yin
- SA Sievers
- SIA Cohen
- SIA Cohen
- SIA Cohen
- SJ Eyles
- SJ Metallo
- SK Nair
- SL Cohen
- T Berg
- T Cohen
- TJ Burke
- TL Blundell
- TL Kukar
- TO Street
- TPJ Knowles
- TPJ Knowles
- UR Chowdhury
- V Csizmok
- V Hornak
- VN Uversky
- VN Uversky
- VN Uversky
- VN Uversky
- VN Uversky
- W Bermel
- W Bode
- W Kim
- WA Lea
- X Yin
- X Zheng
- Y Cheng
- Y Shimmyo
- Y Xie
- Y Xu
- Z Lv
- Z Solyom
- Publication venue
- Cellular and Molecular Life Sciences
- Publication date
- 19/06/2017
- Field of study
It is generally recognized that a large fraction of the human proteome is made up of proteins that remain disordered in their native states. Despite the fact that such proteins play key biological roles and are involved in many major human diseases, they still represent challenging targets for drug discovery. A major bottleneck for the identification of compounds capable of interacting with these proteins and modulating their disease-promoting behaviour is the development of effective techniques to probe such interactions. The difficulties in carrying out binding measurements have resulted in a poor understanding of the mechanisms underlying these interactions. In order to facilitate further methodological advances, here we review the most commonly used techniques to probe three types of interactions involving small molecules: (1) those that disrupt functional interactions between disordered proteins; (2) those that inhibit the aberrant aggregation of disordered proteins, and (3) those that lead to binding disordered proteins in their monomeric states. In discussing these techniques, we also point out directions for future developments.Gabriella T. Heller is supported by the Gates Cambridge Trust Scholarship. Francesco A. Aprile is supported by a Senior Research Fellowship award from the Alzheimer’s Society, UK (grant number 317, AS-SF-16-003)
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
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- Adenekan B
- Adeniran J
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- Adeniyi A
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- Agbedinu K
- Agius M
- Aglan A
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- Aguilar-Jimenez J
- Aguilera M
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- Ahlonsou G
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- Dias S
- Diaz Vico T
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake TM
- Drake TM
- Drake TM
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Dwydar A
- Ebdewi H
- Ebidy M
- Ebidy MM
- Ebrahim OS
- Eduard P
- Edwards J
- Edye M
- Eid MM
- Eisner L
- Ekow M
- El Ashal G
- El Dahab AA
- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
- Farhad M
- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler AJ
- Fozard T
- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
- Gad MO
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaignard E
- Gaignard E
- Gaizauskas V
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
- Galvez CP
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
- Gan C
- Gan YY
- Gani MA
- Garaycochea O
- Garcia Bernardo C
- Garcia Florez LJ
- Garcia Septiem J
- Garcia Torres CP
- Garcia-Florez L
- Garland A
- Gash K
- Gash K
- Gash K
- Gastaldi P
- Gasteratos K
- Gaujoux S
- Gavagna L
- Gbessi DG
- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
- Germanos S
- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
- Ghandora N
- Ghanem A
- Ghanem E
- Ghanem S
- Ghanem S
- Ghannam M
- Gharib A
- Gharib A
- Ghazy AA
- Gheith A
- Ghetia M
- Ghetia M
- Ghonaim MA
- Ghoneem M
- Ghoneim O
- Giacci L
- Giardino FR
- Giavarini L
- Giglio MC
- Gilbert R
- Gilbert RW
- Giles J
- Gillespie M
- Gimzewska M
- Giraldo RSR
- Giuliani S
- Giuliani S
- Giuriato TF
- Gkiokas G
- Glasbey J
- Glasbey J
- Glasbey JC
- GlobalSurg Collaborative
- Glover TE
- Glover-Addy H
- Glynn M
- Gobin N
- Gobin N
- Goh CC
- Goh CC
- Goh W
- Gohar ME-SAM
- Gokani S
- Goldin E
- Golding D
- Gomaa A
- Gomah M
- Gonzales Montejo MS
- Gonzales Stuva JP
- Gonzalez M
- Goodstein M
- Gosling S
- Gosling SG
- Gouda A
- Gould L
- Gouldthorpe C
- Gouvas N
- Gouws J
- Graffeille V
- Graffieille V
- Gran M
- Grandinetti PP
- Grant A
- Grasset E
- Grasset E
- Grassi V
- Gratton R
- Gravante G
- Gravante G
- Gray D
- Grech N
- Green N
- Grella MG
- Gribauskaite J
- Griffiths E
- Griffiths E
- Griffiths M
- Grima T
- Grisin E
- Grizhja B
- Grobler DC
- Grosos C
- Grossart C
- Gubeli A
- Gudal A
- Gudal A
- Gudal A
- Gudlaugsdottir K
- Guevara Torres S
- Guevara R
- Guglielmo V
- Gui D
- Gul E
- Gulbinas A
- Gulcicek OB
- Gulielmi A
- Gultom PA
- Gumar M
- Gunaseelan K
- Gunawan R
- Guner A
- Gunnarsson U
- Guo W
- Gupta A
- Gustafsson U
- Guzman Duenas C
- Gyamfi FE
- Gyanchandani N
- Gyedu A
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- Habeeb O
- Habeebullah A
- Hache-Marliere M
- Haddad N
- Hafez AT
- Hafez M
- Hafez M
- Hafez S
- Haffreingue A
- Hafiz S
- Hagan R
- Hagar A
- Haines M
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- Hajeh H
- Hakim H
- Halhouli O
- Halhouli O
- Halicioglu I
- Hall E
- Hall N
- Hall NJ
- Hall TF
- Hallam S
- Haloho A
- Hamad MGM
- Hamarshi A
- Hamasaki Hamaguchi JL
- Hamasaki J
- Hamdan A
- Hamdan M
- Hamed MF
- Hamill D
- Hammad A
- Hammad A
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- Hampton M
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- Hamsho W
- Hanafy M
- Hand C
- Hanks A
- Hanley I
- Hanoun S
- Hanrahan M
- Hanrahan M
- Hanrahan M
- Hanrahan M
- Hantour U
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- Hany E
- Haque M
- Har PAL
- Haraux E
- Harbord P
- Haroun A
- Harper E
- Harrison EM
- Harrison EM
- Harrison N
- Harrison P
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- Hartford L
- Harvey N
- Hasan A
- Hasan A
- Hasan D
- Hasanah A
- Hasanain D
- Hascoet J
- Hashad E
- Hasheminia A
- Hashim A
- Hashish A
- Hashish M
- Haslegrave A
- Hassaan A
- Hassaan A
- Hassan A
- Hassan A
- Hassan A
- Hassan ATA
- Hassan I
- Hassan M
- Hassan OMM
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- Hassan Z
- Hassanain M
- Hassanain M
- Hassanein AB
- Havemann I
- Hawkins W
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- Hegazy EM
- Hegazy Y
- Helene F-C
- Helguero-Santin LM
- Hemeda D
- Hemingway D
- Hemmila M
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- Henderson L
- Henderson L
- Heng HE
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- Henshall DE
- Herebat A
- Herikstad R
- Herrera Matta JJ
- Herrera Puma CM
- Herrera N
- Herrera-Matta J
- Herrod P
- Hervieux E
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- Hesham O
- Hettiarachchi TS
- Hewage K
- Heywood EG
- Highcock S
- Hilal K
- Hinojosa C
- Hjertberg M
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- Hmila S
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- Huaman E
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- Hutch W
- Huwait A
- Iacono C
- Iannone I
- Ibraheem AAF
- Ibraheem HI
- Ibrahem AA
- Ibrahem AA
- Ibrahim A
- Ibrahim A
- Ibrahim A
- Ibrahim AM
- Ibrahim E
- Ibrahim EM
- Ibrahim I
- Ibrahim K
- Ibrahim M
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- Ibrahim Y
- Idress T
- Idris F
- Idris SAI
- Iftekhar F
- Iftikhar Z
- Iftikhar Z
- Ignatavicius P
- Ihediwa G
- Imoro O
- Ingabire JCA
- Ingabire JCA
- Ingabire JCA
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- Ioannidis O
- Iordache F-M
- Iqbal FM
- Iqbal MR
- Ireland P
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- Kamarulzamil SNA
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- Kanani A
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- Merlo MS
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- Mohamed M
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- Samaraweera DI
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- Tansoker I
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- Ukwenya Y
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- Urbanavicius L
- Urbina Rojas NM
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- Wondoh P
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- Wong CS
- Wong CY
- Wong F
- Wong HY
- Wood G
- Woodward H
- Worku M
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- Worku T
- Wredberg C
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- Wright NJ
- Xerri T
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- Yahaya MT
- Yakubu M
- Yallop L
- Yam SY
- Yang J
- Yap S
- Yaseen T
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- Yau JD
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- Yeang LJ
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- Yeo LS
- Yeung ENW
- Yeung MHA
- Yifieyeh A
- Yildirim R
- Yip C
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif JH
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- Yusufali T
- Zaa'treh R
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- Zalabia MF
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- Zanini N
- Zanini N
- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zeta Solis LA
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
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- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Methods of probing the interactions between small molecules and disordered proteins
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- A Mashaghi
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- ACM Ferreon
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- FA Aprile
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- GT Heller
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- K Wüthrich
- K-C Jeong
- KA Conway
- KC Neuman
- KS Molnar
- KX Wang
- L Konermann
- L Xu
- L Young
- LI Iconaru
- LM Iakoucheva
- LM Young
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- M Fuxreiter
- M Fuxreiter
- M Groenning
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- Marsh Ja
- MC Chartier-Harlin
- MD Carter
- MG Fried
- MH Polymeropoulos
- Michele Vendruscolo
- MM Babu
- MR Cookson
- MR Hansen
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- N Gassler
- N Krishnan
- N Tjandra
- NH Pawley
- NJ Greenfield
- NP Cowieson
- P Arosio
- P Arosio
- P Bernadó
- P Bernadó
- P Ibáñez
- P Joshi
- P Schanda
- P Sormanni
- P Sormanni
- P Tompa
- P Tompa
- P Tompa
- P Tompa
- PE Wright
- Q-L Ma
- R Beveridge
- R Cuchillo
- R Hovius
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- S Gil
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- S Shangary
- S Yin
- SA Sievers
- SIA Cohen
- SIA Cohen
- SIA Cohen
- SJ Eyles
- SJ Metallo
- SK Nair
- SL Cohen
- T Berg
- T Cohen
- TJ Burke
- TL Blundell
- TL Kukar
- TO Street
- TPJ Knowles
- TPJ Knowles
- UR Chowdhury
- V Csizmok
- V Hornak
- VN Uversky
- VN Uversky
- VN Uversky
- VN Uversky
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- W Bermel
- W Bode
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- X Yin
- X Zheng
- Y Cheng
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- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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- De Franciscis S
- De Freitas AVC
- De La Medina AR
- de Leó
- De Leon MZP
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- de Lima CVB
- De Luca E
- De Marco P
- De Sousa AV
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- Deane C
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- Decker E
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- Dedey F
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- Del Basso C
- Del Pilar Paucar A
- Delforge X
- Delgado Jm
- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
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- Despotidis V
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- Devadasar Gh
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- Diab A
- Diaconescu B
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- Dias S
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- Din F
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- Dissanayake T
- Djivoh F
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- Dragatas D
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- Duane T
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- El Halawany M
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- El Hamid NA
- El Jamassi A
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- El Mesery S
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- El Sayed IM
- El Shoura Y
- El Slam MA
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- El-Din Ra
- El-Din Sa
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- El-Kashef H
- El-Latif Nka
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- El-Sagheer N
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- Eldamaty L
- Eldeeb Az
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- Elhamouly S
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- Elhoseny G
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- Elkadsh I
- Elkady F
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- Elkelany A
- Elkhadrawi M
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- Elkorashy Am
- Ellison Q
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- Elzowawi F
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- Eyssartier E
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- Faccincani R
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- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
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- Fermani C
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- Fernandez-Bueno F
- Fernandez-Vega L
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- Fontana T
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- Forno W
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- Fowler Aj
- Fozard T
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- Frade F
- Fraga Gp
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- Fujii F
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- Grizhja B
- Grobler Dc
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- Guevara R
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- Halhouli O
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- Halicioglu I
- Hall E
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- Hamarshi A
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- Hasanah A
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- Hashad E
- Hasheminia A
- Hashim A
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- Haslegrave A
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- Hassaan A
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- Ibrahem Aa
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- Ibrahim A
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- Ibrahim Am
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- Ibrahim I
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- Ibrahim M
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- Imoro O
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- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud Ma
- Mahmoud Mi
- Mahmoud S
- Mahmoud Sme
- Mahmud K
- Maillot B
- Maimbo M
- Maimbo M
- Mairs Ng
- Maison K
- Maistry N
- Majauskyté
- Majbar A
- Majid Ahha
- Majid K
- Major Cp
- Major P
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- Mak T
- Mak T
- Makama J
- Makinde M
- Makupe A
- Malavenda M
- Malik K
- Malik P
- Malik Ta
- Mamdouh E
- Mamdouh R
- Manatakis Dk
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
- Marey As
- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
- Mcaleer E
- Mcaleer S
- Mccarthy K
- Mccarthy M
- Mccarthy M
- McCullagh D
- Mcdonald R
- McGarvie S
- Mcguigan A
- McIntosh K
- Mcintosh R
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- Mcintyre N
- Mcintyre R
- Mckechnie D
- Mclachlan G
- Mclean Al
- Mclean K
- McMorran D
- Mcnish D
- Mcphee A
- Mealy K
- Mehdi A
- Mehrez S
- Mejia Agv
- Melo R
- Melo R
- Mendel H
- Mendez M
- Mendez N
- Mendizabal Caa
- Mendoza I
- Menegussi J
- Mensah E
- Menshawy A
- Mentula P
- Meqbil J
- Mericliler M
- Merlini D
- Merlini D
- Merlo Ms
- Mesbah N
- Meshref A
- Metwally Mm
- Migliore M
- Miguel Gps
- Mihaljevic Al
- Mihanovic J
- Mihanovic J
- Mijuskovic B
- Mikalauskas S
- Mikalauskas S
- Mikuckyte D
- Mikwar Z
- Milligan W
- Milligan W
- Mingrone P
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
- Mironescu As
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
- Mitroudis N
- Mittal A
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- Miyasato Hs
- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
- Morgan C
- Morshedy Em
- Morsi A
- Morsi M
- Morton D
- Morton D
- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
- Muntean Li
- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
- Mustafa M
- Mustafa M
- Mustafa Ma
- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
- Mutlu V
- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
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- Nasr M
- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
- Nawawi A
- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
- Ne&apos
- Negida A
- Negoi I
- Nel D
- Nemeth K
- Neo Yn
- Neo Yt
- Neophytou C
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nesaratnam A
- Nessa A
- Nestorovic M
- Nevieraite V
- Newton T
- Ng S
- Ng Yk
- Ng Zh
- Ngayu N
- Ngwa Te
- Niazi Ak
- Nicholson L
- Nighat B
- Nigo S
- Nikberg M
- Nikoloudis N
- Nikoloudis N
- Niragire A
- Niranjan N
- Nirumal Mk
- Niska K
- Nita Ge
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- Niyirera E
- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
- Normile C
- North As
- Notarnicola M
- Notarnicola M
- Nouh T
- Nouh T
- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
- Nymo L
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- Obute Rd
- Occhionorelli S
- Odeyemi B
- Odeyemi B
- Odutola O
- Ogunsua O
- Ogunyemi A
- Oh J
- Oh J
- Ohene-Yeboah M
- Ojeda Rrb
- Okenabirhie O
- Olajide To
- Olaolorun A
- Olivier J
- Olori S
- Olori S
- Oludara M
- Oludara M
- Olugbemi M
- Omar Aa
- Omar Me
- Omar Mfw
- Omara S
- Omer Oa
- Onimowo J
- Onuoha C
- Oosterkamp A
- Opoku-Agyeman R
- Oram S
- Orbegozo Pat
- Orchard M
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- Ortega-Vazquez I
- Ortiz N
- Orton P
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- Osei-Nketiah S
- Oshati O
- Oshodi O
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- Osinowo A
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- Osman O
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- Othman M
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- Oumer R
- Owen C
- Owusu F
- Owusu F
- Ozben V
- Ozkan Bb
- Ozkan Bb
- Ozkan Bb
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- Paž
- Pabla G
- Pacheco Rda
- Padmore G
- Pagano G
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- Pagnozzi J
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- Palliyil M
- Palliyil Mm
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- Palma Af
- Paludi Ma
- Paludi Ma
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- Panez Wr
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- Panteli C
- Papageorgiou D
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- Papandrea M
- Papaskarlatos Ia
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- Parreno-Sacdalan Md
- Parseliunas A
- Parthiban S
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- Pasquali S
- Pastora J
- Pata D
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- Pata F
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- Pata F
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- Patoulias I
- Paul M
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- Perino M
- Peros G
- Perrotta G
- Pesenti G
- Petrikenas S
- Peycelon M
- Peycelon M
- Pezas T
- Pezas T
- Pezelj N
- Phillips N
- Picardo A
- Picciariello A
- Pimenta Ml
- Pineñ
- Pinkney T
- Pinkney Td
- Pinnagoda K
- Pino W
- Pitt Sk
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- Pluke K
- Poš
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- Popoola A
- Porter J
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- Poskus T
- Poskus T
- Poskus T
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- Powell A
- Pozo Dar
- Prabhudesai A
- Pranevicius R
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- Preckailaite E
- Primavesi F
- Prins M
- Proctor Vk
- Pronin S
- Prudhomme T
- Psaila J
- Psarianos K
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- Pugliesi Tb
- Pujol-Cano N
- Puma Cmh
- Punja V
- Purwaningsih Na
- Puttick M
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- Qawasmi I
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- Quezada Jhj
- Qumbos Aa
- Qureshi Au
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- Radojkovic M
- Rahantasoa Fcfp
- Rahmah Df
- Rahmawati Fn
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- Rajmohan S
- Rakauskas R
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- Ramadan Mt
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- Rashad M
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- Rashwan H
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- Rasoaherinomenjanahary F
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- Raza A
- Raza I
- Raza I
- Razek T
- Razmdjou S
- Razuri C
- Razzaque J
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- Recinos G
- Recinos G
- Recinos G
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- Reda A
- Reddy Y
- Redgrave N
- Redota Map
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- Rees Cm
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- Renaux-Petel M
- Restrepo Im
- Restrepo J
- Reunis E
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- Riente F
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- Ripa M
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- Robert E
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- Roche Mo
- Rocke A
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- Rodriguez X
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- Runigamugabo E
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- Saad Ha
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- Sabour Fa
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- Sahel S
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- Salama M
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- Sallinen V
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- Salma M
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- Samaniego Cs
- Samaraweera Di
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- Sammarco G
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- Schivo D
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- Senanayake Kj
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- Septiem Jg
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- Shahbaz Ar
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- Soeselo Da
- Sokratous A
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- Urniež
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- Vasquez I
- Veen T
- Vega Gmm
- Vega Gmm
- Velá
- Velá
- Velasquez R
- Vella-Baldacchino M
- Venclauskas L
- Vendramin E
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venugopal C
- Verbeek A
- Vergara Alc
- Verjee A
- Vermaas M
- Veronese E
- Viš
- Vianna P
- Vicario E
- Vico Td
- Vida Lc
- Vida Lc
- Vilč
- Villa R
- Villalobos S
- Villegas Mi
- Vimalachandran D
- Vincent J
- Violi P
- Vivekanantham S
- Vlachogiorgos A
- Voulgaris E
- Vth Le
- Wael N
- Wagener M
- Wakefield R
- Walę
- Waleed H
- Walker M
- Walker N
- Walls L
- Walsh M
- Walsh U
- Waqar M
- Ward Ae
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick Am
- Waterman A
- Watson Nf
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein Ms
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini Ta
- Widmer Lw
- Wijayarathna Ls
- Wild Jrl
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson Ms
- Wilson Msj
- Wimalge Pmsn
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
- Woin E
- Wold Tb
- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong Cs
- Wong Cy
- Wong F
- Wong Hy
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright Nj
- Xerri T
- Xerri T
- Yahaya Mt
- Yakubu M
- Yallop L
- Yam Sy
- Yang J
- Yap S
- Yaseen T
- Yaseen Tm
- Yau Jd
- Yavuz Ma
- Ye J
- Yeang Lj
- Yee J
- Yeo Ls
- Yeung En
- Yeung Mha
- Yifieyeh A
- Yildirim R
- Yip C
- Yip Sbs
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong Co
- Yong Gl
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif Jh
- Yuksek Ma
- Yusufali T
- Zaa&apos
- Zachariades Dc
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
- Zakaria Y
- Zaki A
- Zakir M
- Zalabia Mf
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
- Zanini N
- Zanini N
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zerihun Ab
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zimmermann Ef
- Zohair A
- Zorrilla Cd
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbü
- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Cystatin C - an accurate marker of glomerular filtration rate after renal transplantation?
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Comparison of astigmatism prediction error taken with the Pentacam measurements, Baylor nomogram, and Barrett formula for toric intraocular lens implantation
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ambulatory blood pressure and Doppler echocardiographic indexes of borderline hypertensive men presenting an exaggerated blood pressure response during dynamic exercise
- Author
- Boutouyrie P
- Bruce RA
- Chaitman BR
- Choong CY
- Devereaux RB
- Diazuzumba SB
- Dlin RN
- E.C. Vasquez
- E.G. Lima
- Eliason K
- Everson SA
- F.L. Herkenhoff
- Fagard R
- Fragola PV
- Fuad FM
- Graettinger WF
- Graettinger WF
- Hines EA
- ISH Scientific Committee
- J.G. Mill
- Jern S
- Kannel WB
- Kohler T
- Lafleche AB
- Mabaroti C
- Mancia G
- Mancia G
- Manolio TA
- Mantero A
- Matthews KA
- Mundal R
- Naughton JP
- Parati G
- Perloff DB
- Perloff DB
- Pickering TG
- Pickering TG
- Sahn DJ
- Sherwood A
- Stroop JP
- Sung BH
- Toto-Moukouo J
- Weder AB
- Publication venue
- Associação Brasileira de Divulgação Científica
- Publication date
- 01/10/2001
- Field of study
Borderline hypertension (BH) has been associated with an exaggerated blood pressure (BP) response during laboratory stressors. However, the incidence of target organ damage in this condition and its relation to BP hyperreactivity is an unsettled issue. Thus, we assessed the Doppler echocardiographic profile of a group of BH men (N = 36) according to office BP measurements with exaggerated BP in the cycloergometric test. A group of normotensive men (NT, N = 36) with a normal BP response during the cycloergometric test was used as control. To assess vascular function and reactivity, all subjects were submitted to the cold pressor test. Before Doppler echocardiography, the BP profile of all subjects was evaluated by 24-h ambulatory BP monitoring. All subjects from the NT group presented normal monitored levels of BP. In contrast, 19 subjects from the original BH group presented normal monitored BP levels and 17 presented elevated monitored BP levels. In the NT group all Doppler echocardiographic indexes were normal. All subjects from the original BH group presented normal left ventricular mass and geometrical pattern. However, in the subjects with elevated monitored BP levels, fractional shortening was greater, isovolumetric relaxation time longer, and early to late flow velocity ratio was reduced in relation to subjects from the original BH group with normal monitored BP levels (P<0.05). These subjects also presented an exaggerated BP response during the cold pressor test. These results support the notion of an integrated pattern of cardiac and vascular adaptation during the development of hypertension
Transpressional tectonics and nappe stacking along the Southern Variscan Front of Morocco
- Author
- A Michard
- A Piqué
- A Sebai
- Alessandro Ellero
- Andrea Cerrina Feroni
- B Kübler
- B Kübler
- B Tikoff
- C Choubert
- C Hoepffner
- D Gasquet
- D Shelley
- E Landing
- E Tavarnelli
- EA Toto
- Giovanni Musumeci
- Giuseppe Ottria
- H Hollard
- H Ouanaimi
- J Hindermeyer
- JC Ramsay
- JJ Álvaro
- JP Brun
- JS Oldow
- KB Knight
- Leonardo Leoni
- M Berrahma
- M Hubbard
- M Lezzerini
- M Malusà
- M Malusà
- M Mattauer
- Marco G. Malusà
- MR Houari
- N Hamoumi
- P Matte
- Riccardo Polino
- RR Jones
- S Soualhine
- W Buggisch
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Renal-Artery Stenosis
- Author
- Beregi JP
- Blaufox MD
- Boisclair C
- Border WA
- Cambria RP
- Canzanello VJ
- Caps MT
- Chaikof EL
- Conlon PJ
- Dean RH
- Diehl JT
- Dorros G
- Guzman RP
- Hollenberg NK
- Jackson B
- Kaufman JA
- Kidney D
- Klinge J
- Libertino JA
- Libertino JA
- Mailloux LU
- Novick AC
- O'Neill EA
- Oei HY
- Plouin PF
- Reilly JM
- Roche Z
- Sang CN
- Sawicki PT
- Scoble JE
- Setaro JF
- Shanley PF
- Sigmon DH
- Sos TA
- Tegtmeyer CJ
- Textor SC
- Textor SC
- Toto RD
- Xue F
- Zierler RE
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- Field of study
The Tectonic and Geological Environment of Coastal South America
- Author
- AMP Mizusaki
- Bowin C (1976) Caribbean gravity field and plate tectonics. Geol Soc Am Spec Pap 169 Lande SC Leslie RB
- C Dengo
- C Hoorn
- C Mpodozis
- DL Inman
- E Norabuena
- EA Toto
- EJ Milani
- FC Ponte
- G Keller
- Gonzalez-Ferran 0
- H Duque-Caro
- H Duque-Caro
- HAO Ojeda
- HD Rangel
- HE Asmus
- HG Greene
- HK Chang
- J Bourgois
- J Macharé
- JC Vicente
- JE Case
- JF Dewey
- JL Pindell
- JN Kellogg
- KG Souza
- KHA Gohrbandt
- L Keigwin
- LAP Gamboa
- LFG de Almeida
- LS Demercian
- M Barazangi
- M Schmitz
- MA Gutscher
- MA Gutscher
- PD Rabinowitz
- PE Potter
- PR Cobbold
- PV Zalân
- R von Huene
- RMD Matos
- RW Allmendinger
- SB Kroonenberg
- WD Pennington
- WU Mohriak
- WU Mohriak
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2001
- Field of study