Mapping Nairobi's dairy food system: An essential analysis for policy, industry and research

Demand for dairy products in sub-Saharan Africa, is expected to triple by 2050, while limited increase in supply is predicted. This poses significant food security risk to low income households. Understanding how the dairy food system operates is essential to identify mitigation measures to food insecurity impact. This study aims to determine the structure and functionality of Nairobi's dairy system using a value chain mapping approach

Quantifying the burden of rhodesiense sleeping sickness in Urambo district, Tanzania

Sleeping sickness (human African trypanosomiasis - HAT) is a disease transmitted by tsetse flies and is always fatal if left untreated. The disease occurs in foci affecting poor communities with limited access to health service provision and as such the disease is often left undiagnosed, mistaken for more common afflictions. Even if diagnosed, sleeping sickness is costly to treat, both for health services and patients and their families in terms of costs of diagnosis, transport, hospital care, and the prolonged period of convalescence. Here we estimate the health burden of the acute form T. b. rhodesiense sleeping sickness in Urambo District, Tanzania in terms of Disability Adjusted Life Years (DALYs), the yardstick commonly used by policy makers to prioritize disease management practices, representing a year of healthy life lost to disease. In this single district, the burden of the disease over one year was estimated at 979 DALYs and the estimated monetary costs to health services for the 143 treated patients at US$11,841 and to the patients themselves at US$ 3,673 for direct medical costs and US$ 9,781 for indirect non-medical costs. Sleeping sickness thus places a considerable burden on the affected rural communities and health services

Control of Taenia solium; a case for public and private sector investment

The zoonotic helminth T. solium is one of the leading causes of acquired epilepsy in endemic countries, resulting in a high burden both in human health and social stigma of affected people (1-3). In 2012 T. solium was highlighted as a priority for control in the World Health Assembly resolution 66.12 (4). Despite a call for validated control strategies by 2015 and a “Tool Kit” of control options being available, relatively few examples of successfully implemented and sustainable control programs are available (5-7). A minimal control strategy focusing solely on the porcine host has also been proposed although the cost-effectiveness of such has yet to be explored (8). Although acknowledgment has been made of the need for initiatives to be sustainable, we are yet to see sufficient consideration of the balance between the provision of public and private goods, and the need for engagement of the people and organizations in the pork value chains within T. solium control strategies. We utilized a food chain risk analysis model to determine the incremental cost-effectiveness ratio (ICER) in terms of $/infective meal avoided, of combining a pharmaceutical intervention in pigs with strengthened meat hygiene services. The addition of a vaccination and treatment protocol, at an additional 10.3% cost, was illustrated to have the potential to improve the ICER of improving meat inspection by 74.6%. The vaccination and treatment protocol also had the potential to reduce the losses borne by the pork industry of condemned meat by 66%, highlighting the potential to leverage private sector investment in T. solium control.</p

Giant Anisotropy of Spin-Orbit Splitting at the Bismuth Surface

We investigate the bismuth (111) surface by means of time and angle resolved photoelectron spectroscopy. The parallel detection of the surface states below and above the Fermi level reveals a giant anisotropy of the Spin-Orbit (SO) spitting. These strong deviations from the Rashba-like coupling cannot be treated in $\textbf{k}\cdot \textbf{p}$ perturbation theory. Instead, first principle calculations could accurately reproduce the experimental dispersion of the electronic states. Our analysis shows that the giant anisotropy of the SO splitting is due to a large out-of plane buckling of the spin and orbital texture.Comment: 5 pages, 4 figure

The VIMOS VLT Deep Survey - Evolution of the luminosity functions by galaxy type up to z=1.5 from first epoch data

From the first epoch observations of the VVDS up to z=1.5 we have derived luminosity functions (LF) of different spectral type galaxies. The VVDS data, covering ~70% of the life of the Universe, allow for the first time to study from the same sample and with good statistical accuracy the evolution of the LFs by galaxy type in several rest frame bands from a purely magnitude selected sample. The magnitude limit of the VVDS allows the determination of the faint end slope of the LF with unprecedented accuracy. Galaxies have been classified in four spectral classes, using their colours and redshift, and LFs have been derived in the U, B, V, R and I rest frame bands from z=0.05 to z=1.5. We find a significant steepening of the LF going from early to late types. The M* parameter is significantly fainter for late type galaxies and this difference increases in the redder bands. Within each of the galaxy spectral types we find a brightening of M* with increasing redshift, ranging from =< 0.5 mag for early type galaxies to ~1 mag for the latest type galaxies, while the slope of the LF of each spectral type is consistent with being constant with redshift. The LF of early type galaxies is consistent with passive evolution up to z~1.1, while the number of bright early type galaxies has decreased by ~40% from z~0.3 to z~1.1. We also find a strong evolution in the normalization of the LF of latest type galaxies, with an increase of more than a factor 2 from z~0.3 to z~1.3: the density of bright late type galaxies in the same redshift range increases of a factor ~6.6. These results indicate a strong type-dependent evolution and identifies the latest spectral types as responsible for most of the evolution of the UV-optical luminosity function out to z=1.5.Comment: 18 pages with encapsulated figures, revised version after referee's comments, accepted for publication in A&

The VIRMOS deep imaging survey: I. overview and survey strategy

This paper presents the CFH12K-VIRMOS survey: a deep B, V, R and I imaging survey in four fields totalling more than 17 deg^2, conducted with the 30x40 arcmin^2 field CFH-12K camera. The survey is intended to be a multi-purpose survey used for a variety of science goals, including surveys of very high redshift galaxies and weak lensing studies. Four high galactic latitude fields, each 2x2 deg^2, have been selected along the celestial equator: 0226-04, 1003+01, 1400+05, and 2217+00. The 16 deg^2 of the "wide" survey are covered with exposure times of 2h, 1.5h, 1h, 1h, while the 1.3x1 deg^2 area of the "deep" survey at the center of the 0226-04 field is covered with exposure times of 7h, 4.5h, 3h, 3h, in B,V,R and I respectively. The data is pipeline processed at the Terapix facility at the Institut d'Astrophysique de Paris to produce large mosaic images. The catalogs produced contain the positions, shape, total and aperture magnitudes for the 2.175 million objects. The depth measured (3sigma in a 3 arc-second aperture) is I_{AB}=24.8 in the ``Wide'' areas, and I_{AB}=25.3 in the deep area. Careful quality control has been applied on the data as described in joint papers. These catalogs are used to select targets for the VIRMOS-VLT Deep Survey, a large spectroscopic survey of the distant universe (Le F\`evre et al., 2003). First results from the CFH12K-VIRMOS survey have been published on weak lensing (e.g. van Waerbeke & Mellier 2003). Catalogs and images are available through the VIRMOS database environment under Oracle ({\tt http://www.oamp.fr/virmos}). They will be open for general use on July 1st, 2003.Comment: 17 pages including 9 figures, submitted to A&

Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts

The recent recognition of neurocysticercosis as a major cause of epilepsy in Uganda and changes in pig demography have lead to a need to better understand the basic epidemiology of Taenia solium infections in pigs and humans. Human exposure is a function of the size of the animal reservoir of this zoonosis. This is the first field survey for porcine cysticercosis to investigate the prevalence of antigen-positive pigs across an entire rural district of south-east Uganda. In our field surveys, 8.6% of 480 pigs screened were seropositive for the parasite by B158/B60 Ag-ELISA. In addition, of the 528 homesteads surveyed 138 (26%) did not have pit latrines indicating a high probability of pigs having access to human faeces and thus T. solium eggs. This study thus indicates the need for better data on this neglected zoonotic disease in Uganda, with a particular emphasis on the risk factors for infection in both pigs and humans. In this regard, further surveys of pigs, seroprevalence surveys in humans and an understanding of cysticercosis-related epilepsy are required, together with risk-factor studies for human and porcine infections

Incorporating scale dependence in disease burden estimates:the case of human African trypanosomiasis in Uganda

The WHO has established the disability-adjusted life year (DALY) as a metric for measuring the burden of human disease and injury globally. However, most DALY estimates have been calculated as national totals. We mapped spatial variation in the burden of human African trypanosomiasis (HAT) in Uganda for the years 2000-2009. This represents the first geographically delimited estimation of HAT disease burden at the sub-country scale.Disability-adjusted life-year (DALY) totals for HAT were estimated based on modelled age and mortality distributions, mapped using Geographic Information Systems (GIS) software, and summarised by parish and district. While the national total burden of HAT is low relative to other conditions, high-impact districts in Uganda had DALY rates comparable to the national burden rates for major infectious diseases. The calculated average national DALY rate for 2000-2009 was 486.3 DALYs/100 000 persons/year, whereas three districts afflicted by rhodesiense HAT in southeastern Uganda had burden rates above 5000 DALYs/100 000 persons/year, comparable to national GBD 2004 average burden rates for malaria and HIV/AIDS.These results provide updated and improved estimates of HAT burden across Uganda, taking into account sensitivity to under-reporting. Our results highlight the critical importance of spatial scale in disease burden analyses. National aggregations of disease burden have resulted in an implied bias against highly focal diseases for which geographically targeted interventions may be feasible and cost-effective. This has significant implications for the use of DALY estimates to prioritize disease interventions and inform cost-benefit analyses