7,955 research outputs found
Flutter: A finite element program for aerodynamic instability analysis of general shells of revolution with thermal prestress
Documentation for the computer program FLUTTER is presented. The theory of aerodynamic instability with thermal prestress is discussed. Theoretical aspects of the finite element matrices required in the aerodynamic instability analysis are also discussed. General organization of the computer program is explained, and instructions are then presented for the execution of the program
Mineral fabrication and golgi apparatus activity in the mouse calvarium
There is diverse opinion about the mechanism of bone mineralization with only intermittent reports of any direct organellar role played by the golgi apparatus (juxtanuclear body). Light and laser confocal microscopy was combined with electron microscopy and elemental EDX (energy dispersive X-ray microanalysis) in comparing “young” osteocytes in situ in fresh and “slam” frozen developing mouse calvarium, with similar cells (MC3T3-E1) maintained in vitro. The distribution of “nascent” electron dense mineral was examined histochemically (von Kossa, GBHA), including tetracycline (TC) staining as a fluorescent complex with bone salt, while golgi body activity was demonstrated by transfection with a specific green fluorescent construct (GFP/mannosidase II). In tissue culture golgi body activity and mineralization were both blocked by brefeldin A (an established golgi inhibitor) and restored by forskolin, enabling an association with mineral fabrication to be quantified as changing fluorescence intensity (AU) of GFP or TC markers. Results from osteocytes in situ supported previous descriptions of intracellular electron dense objects (microspheres and nanospheres) in a juxtanuclear pattern, containing Ca, P and transitory Si, in a spectrum recapitulated in the calcifying culture after 10 days, when GFP fluorophore surged from 71.7 ± 1.4SD to 133.7 ± 2.7SD AU by 14 days (p < 0.0001). At this stage TC fluorophore mean intensity was 23.8 ± 3.7SD AU (14 days) rising to 45.0 ± 5.1SD AU by 17 days, compared to its stationary 21.7 ± 3.6SD when treated 3 days previously with BFA golgi inhibitor (p < 0.0001), until forskolin reversal. It was concluded from the changing juxtanuclear morphology, Si mineralization mediation and the variably controlled activity versus stasis that the inorganic phase of bone is a complex golgi-directed fabrication with implications for bone matrix biology and evolution
Graphitization of small carbonate samples for paleoceanographic research at the godwin radiocarbon laboratory, University of Cambridge
AbstractA new radiocarbon preparation facility was set up in 2010 at the Godwin Laboratory for Palaeoclimate Research, at the University of Cambridge. Samples are graphitized via hydrogen reduction on an iron powder catalyst before being sent to the Chrono Centre, Belfast, or the Australian National University for accelerator mass spectrometry (AMS) analysis. The experimental setup and procedure have recently been developed to investigate the potential for running small samples of foraminiferal carbonate. By analyzing background values of samples ranging from 0.04 to 0.6 mg C along with similar sized secondary standards, the setup and experimental procedures were optimized for small samples. “Background” modern 14C contamination has been minimized through careful selection of iron powder, and graphitization has been optimized through the use of “small volume” reactors, allowing samples containing as little as 0.08 mg C to be graphitized and accurately dated. Graphitization efficiency/fractionation is found not to be the main limitation on the analysis of samples smaller than 0.07 mg C, which rather depends primarily on AMS ion beam optics, suggesting further improvements in small sample analysis might yet be achieved with our methodology.We would like to thank James Rolfe for running the stable isotope measurements, as well as the Royal Society and NERC grant NE/L006421/1 for research support.This is the author accepted manuscript. The final version is available from Cambridge University Press via http://dx.doi.org/10.1017/RDC.2015.
Body Composition Measurement in Children with Cerebral Palsy, Spina Bifida and Spinal Cord Injury: A Systematic Review of the Literature
Pediatric obesity is a major health concern that has an increased prevalence in children with special needs. In order to categorize a child’s weight, an assessment of body composition is needed. Obtaining an accurate body composition measurement in children with special needs has many challenges associated with it. This perplexing scenario limits the provider’s ability to screen, prevent and treat an abnormal weight status in this vulnerable population. This systematic review summarizes common methods of body composition measurements, their strengths and limitations and reviews the literature when measurements were used in children with cerebral palsy, spina bifida and spinal cord injury. Following PRISMA guidelines, 222 studies were identified. The application of the inclusion and exclusion criteria yielded a final sample of nine studies included in this review. Overall, articles reinforced the inconsistencies of body composition measurement and methodology when used with children with special needs. Concerns include small sample sizes, the need to validate prediction equations for this population, and the lack of controlled trials and reporting of measurement methodology. Healthcare providers need to be aware of the complexities associated with measuring body composition in children with special needs and advocate for further testing of these measurements. Additional studies addressing the reliability and validity of these measures are needed to facilitate appropriate health promotion in children
51 Eri and GJ 3305: A 10-15 Myr old binary star system at 30 parsecs
Following the suggestion of Zuckerman et al. (2001, ApJ, 562, L87), we
consider the evidence that 51 Eri (spectral type F0) and GJ 3305 (M0),
historically classified as unrelated main sequence stars in the solar
neighborhood, are instead a wide physical binary system and members of the
young beta Pic moving group (BPMG). The BPMG is the nearest (d < 50 pc) of
several groups of young stars with ages around 10 Myr that are kinematically
convergent with the Oph-Sco-Cen Association (OSCA), the nearest OB star
association. Combining SAAO optical photometry, Hobby-Eberly Telescope
high-resolution spectroscopy, Chandra X-ray data, and UCAC2 catalog kinematics,
we confirm with high confidence that the system is indeed extremely young. GJ
3305 itself exhibits very strong magnetic activity but has rapidly depleted
most of its lithium. The 51 Eri/GJ 3305 system is the westernmost known member
of the OSCA, lying 110 pc from the main subgroups. The system is similar to the
BPMG wide binary HD 172555/CD -64d1208 and the HD 104237 quintet, suggesting
that dynamically fragile multiple systems can survive the turbulent
environments of their natal giant molecular cloud complexes, while still being
imparted high dispersion velocities. Nearby young systems such as these are
excellent targets for evolved circumstellar disk and planetary studies, having
stellar ages comparable to that of the late phases of planet formation.Comment: 27 pages, 7 figures. Accepted for publication in the Astronomical
Journal. For a version with high resolution figures, see
http://www.astro.psu.edu/users/edf/51Eri.pd
Mineral Acquisition from Clay by Budongo Forest Chimpanzees
Chimpanzees of the Sonso community, Budongo Forest, Uganda were observed eating clay and drinking clay-water from waterholes. We show that clay, clay-rich water, and clay obtained with leaf sponges, provide a range of minerals in different concentrations. The presence of aluminium in the clay consumed indicates that it takes the form of kaolinite. We discuss the contribution of clay geophagy to the mineral intake of the Sonso chimpanzees and show that clay eaten using leaf sponges is particularly rich in minerals. We show that termite mound soil, also regularly consumed, is rich in minerals. We discuss the frequency of clay and termite soil geophagy in the context of the disappearance from Budongo Forest of a formerly rich source of minerals, the decaying pith of Raphia farinifera palms
Experimental evaluation of mobile phone sensors
Smart phone has become an important part of people's daily life. Most of current smart phone are equipped with a rich set of built-in sensors. The mobile applications such as geo-location based video annotation and indoor positioning require precise measurements from sensors. In addition, understanding the sensing performance of a smart phone device is helpful for implementing a mobile application that needs sensor data. This paper presents an experimental evaluation of key sensors in a state of the art smart phone - Google Nexus 4. The sensors chosen in the paper are accelerometer, gyroscope, magnetometer and GPS. Substantial tests have been executed to evaluate the sensors' accuracy, precision, maximum sampling frequency, sampling period jitter, energy consumption
Relative spins and excitation energies of superdeformed bands in 190Hg: Further evidence for octupole vibration
An experiment using the Eurogam Phase II gamma-ray spectrometer confirms the
existence of an excited superdeformed (SD) band in 190Hg and its very unusual
decay into the lowest SD band over 3-4 transitions. The energies and dipole
character of the transitions linking the two SD bands have been firmly
established. Comparisons with RPA calculations indicate that the excited SD
band can be interpreted as an octupole-vibrational structure.Comment: 12 pages, latex, 4 figures available via WWW at
http://www.phy.anl.gov/bgo/bc/hg190_nucl_ex.htm
Active Galactic Nuclei under the scrutiny of CTA
Active Galactic Nuclei (hereafter AGN) produce powerful outflows which offer
excellent conditions for efficient particle acceleration in internal and
external shocks, turbulence, and magnetic reconnection events. The jets as well
as particle accelerating regions close to the supermassive black holes
(hereafter SMBH) at the intersection of plasma inflows and outflows, can
produce readily detectable very high energy gamma-ray emission. As of now, more
than 45 AGN including 41 blazars and 4 radiogalaxies have been detected by the
present ground-based gamma-ray telescopes, which represents more than one third
of the cosmic sources detected so far in the VHE gamma-ray regime. The future
Cherenkov Telescope Array (CTA) should boost the sample of AGN detected in the
VHE range by about one order of magnitude, shedding new light on AGN population
studies, and AGN classification and unification schemes. CTA will be a unique
tool to scrutinize the extreme high-energy tail of accelerated particles in
SMBH environments, to revisit the central engines and their associated
relativistic jets, and to study the particle acceleration and emission
mechanisms, particularly exploring the missing link between accretion physics,
SMBH magnetospheres and jet formation. Monitoring of distant AGN will be an
extremely rewarding observing program which will inform us about the inner
workings and evolution of AGN. Furthermore these AGN are bright beacons of
gamma-rays which will allow us to constrain the extragalactic infrared and
optical backgrounds as well as the intergalactic magnetic field, and will
enable tests of quantum gravity and other "exotic" phenomena.Comment: 28 pages, 23 figure
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